scholarly journals Effect of Administration of Lidocaine at Body Temperature on Anesthesia Success in Rodent Model: A Behavior and Electrophysiology Study

2021 ◽  
pp. 1-18
Author(s):  
Sina Kakooei ◽  
◽  
Mohammad Reza Afarinesh ◽  
Masoud Parirokh ◽  
Reza Nikzad ◽  
...  
Keyword(s):  
Body Temperature ◽  
Success Rate ◽  
Room Temperature ◽  
Clinical Medicine ◽  
Cell Membrane Permeability ◽  
Male Rats ◽  
Unit Recording ◽  
Temperature Changes ◽  
Anesthetic Agents ◽  
Different Temperatures

Introduction: Success in anesthesia administration relieves the perception of pain during surgery. Lidocaine is the most commonly used local anesthetic agent in clinical medicine. Moreover, anesthetic agents' temperature changes can influence cell membrane permeability. Here, the effectiveness of different temperatures of lidocaine (Lid.) on anesthesia success rate in rats has been investigated in rats. Methods: Wistar male rats were pretreated by fast lidocaine or saline injection into hind paw or intradermal cheek at room (RT) and body (BT) temperatures (22 and 37 °C, respectively), and rat behaviors were evaluated by formalin-induced hind paw pain and orofacial pain tests, respectively. Moreover, using a single-unit recording technique, the spontaneous activity of the marginal nerve was recorded at room temperature in RT-Lid. and BT-Lid. groups. Results: Data analysis revealed that lidocaine had significant anti-nociceptive effects in both the BT-Lid. and RT-Lid. groups compared to their control groups (p < 0.05). Also, the number of spikes in the BT-Lid. and RT-Lid. groups was significantly lower than their baselines (p < 0.05). However, lidocaine at body temperature decreased the total time spent licking the hind paw, the number of lip rubbings, and the number of spikes firing about 10–15% compared to room temperature. Conclusion: In both behavioral and neural levels of the study, our results showed that an increase in the temperature of lidocaine toward body temperature could increase anesthesia success rate compared to administration of lidocaine at room temperature. This finding can be considered in the treatment of patients.

scholarly journals The effect of temperature change on fluoride uptake from a mouthrinse by enamel specimens

2012 ◽  
Vol 06 (04) ◽  
pp. 361-369 ◽  
Author(s):  
Serdar Baglar ◽  
Adil Nalcaci ◽  
Mustafa Tastekin
Keyword(s):  
Body Temperature ◽  
Room Temperature ◽  
Hot Water ◽  
Effect Of Temperature ◽  
Distilled Water ◽  
Fluoride Solution ◽  
Fluoride Uptake ◽  
Significant Difference ◽  
Human Body Temperature ◽  
Different Temperatures

ABSTRACTObjective: The aim of this study was to examine the effect of temperature on fluoride uptake by enamel specimens from a 0.05% NaF-fluoridated mouthrinse (Oral-B Advantage; Oral-B Laboratories, Newbridge, UK).Methods: Enamel specimens were prepared from extracted human maxillary central incisors. A fluoride-specific ion electrode was used to measure the uptake from a 2 ppm fluoride solution containing 50.0 mL of distilled water, total ion strength adjustment buffer, and fluoridated rinse at 3 different temperatures (room temperature, 25°C; human body temperature, 37°C; hyper-fever temperature, 43°C). One-way analysis of variance and least significant difference were used to assess intragroup and intergroup differences (P<.05).Results: The study found that both the amount and the rate of fluoride uptake increased significantly with increase in temperature. This effect was particularly noticeable at 43°C.Conclusions: The temperature of the NaF mouthrinse may easily and safely be increased beyond room temperature by placing a container of the NaF mouthrinse in a bowl of hot water, allowing greater fluoride penetration into the enamel from the mouthrinse when used at home as a routine prophylactic agent. (Eur J Dent 2012;6:361-369)

scholarly journals Acoustic studies of some non-transforming and transforming special steels at low temperatures

1936 ◽  
Vol 156 (888) ◽  
pp. 383-393 ◽  
Keyword(s):  
Room Temperature ◽  
Maximum Stress ◽  
Brinell Hardness ◽  
Acoustic Method ◽  
Internal Damping ◽  
Temperature Changes ◽  
Point Reduction ◽  
Different Temperatures ◽  
Reduction Of Area ◽  
Special Steels

The present investigation on some special steels and on Swedish charcoal iron was undertaken at the request of Sir Robert Hadfield, following my published note describing a simple acoustic method of studying the presistence of vibration of transversely vibrating metals bars at different temperatures. In the present work the vibration frequencies have also been determined. The r wo series of observations give information regarding the internal damping and Young's elastic modulus respectively. Secular as well as temperature changes have been recorded in transforming nickel steels. The experiments have been made between -183ºC and room temperature, and the results, whenever possible, compared with the Hadfield, Dewar-Hadfield, and De Hass-Hadfield low temperature researches on the maximum stress, elongation, yield point, reduction of area, and Brinell hardness of some of the same steels ( see Table III). A list of the materials investigated is given in Table I, together with the data supplied by Sir Robert Hadfield regarding their composition, treatment, Brinell hardness, and specfic magnetism.

scholarly journals Stability of the Combination of Ceftazidime and Cephazolin in Icodextrin or PH Neutral Peritoneal Dialysis Solution

2014 ◽  
Vol 34 (2) ◽  
pp. 212-218 ◽  
Author(s):  
Rahul P. Patel ◽  
Madhur D. Shastri ◽  
Mohammad Bakkari ◽  
Troy Wanandy ◽  
Matthew D. Jose
Keyword(s):  
Peritoneal Dialysis ◽  
Body Temperature ◽  
High Performance ◽  
Room Temperature ◽  
Storage Conditions ◽  
Initial Concentration ◽  
Dialysis Solution ◽  
Different Temperatures ◽  
Colour Changes ◽  
The Stability

IntroductionThe objective of this study was to investigate the stability of ceftazidime and cephazolin in a 7.5% icodextrin or pH neutral peritoneal dialysis (PD) solution.MethodsCeftazidime and cephazolin were injected into either a 7.5% icodextrin or pH neutral PD bag to obtain the concentration of 125 mg/L of each antibiotic. A total of nine 7.5% icodextrin or pH neutral PD bags containing ceftazidime and cephazolin were prepared and stored at 1 of 3 different temperatures: 4°C in a domestic refrigerator; 25°C at room temperature; or 37°C (body temperature) in an incubator. An aliquot was withdrawn immediately before (0 hour) or after 12, 24, 48, 96, 120, 144, 168 and 336 hours of storage. Each sample was analyzed in duplicate for the concentration of ceftazidime and cephazolin using a stability-indicating high-performance liquid chromatography technique. Ceftazidime and cephazolin were considered stable if they retained more than 90% of their initial concentration. Samples were also assessed for pH, colour changes and evidence of precipitation immediately after preparation and on each day of analysis.ResultsCeftazidime and cephazolin in both types of PD solution retained more than 90% of their initial concentration for 168 and 336 hours respectively when stored at 4°C. Both of the antibiotics lost more than 10% of the initial concentration after 24 hours of storage at 25 or 37°C. There was no evidence of precipitation at any time under the tested storage conditions. Change in the pH and color was observed at 25 and 37°C, but not at 4°C.ConclusionPremixed ceftazidime and cephazolin in a 7.5% icodextrin or pH neutral PD solution is stable for at least 168 hours when refrigerated. This allows the preparation of PD bags in advance, avoiding the necessity for daily preparation. Both the antibiotics are stable for at least 24 hours at 25 and 37°C, permitting storage at room temperature and pre-warming of PD bags to body temperature prior to its administration.

Comparative Labelling and Biokinetic Studies of 99mTc-EDTA(Sn) and 99mTc-DTPA(Sn)

1977 ◽  
Vol 16 (01) ◽  
pp. 30-35 ◽  
Author(s):  
N. Agha ◽  
R. B. R. Persson
Keyword(s):  
Complex Formation ◽  
Significant Influence ◽  
Room Temperature ◽  
Ph Value ◽  
Maximum Activity ◽  
Reduction Step ◽  
Labelling Yield ◽  
Different Temperatures ◽  
Kinetics Of

SummaryGelchromatography column scanning has been used to study the fractions of 99mTc-pertechnetate, 99mTcchelate and reduced hydrolyzed 99mTc in preparations of 99mTc-EDTA(Sn) and 99mTc-DTPA(Sn). The labelling yield of 99mTc-EDTA(Sn) chelate was as high as 90—95% when 100 μmol EDTA · H4 and 0.5 (Amol SnCl2 was incubated with 10 ml 99mTceluate for 30—60 min at room temperature. The study of the influence of the pH-value on the fraction of 99mTc-EDTA shows that pH 2.8—2.9 gave the best labelling yield. In a comparative study of the labelling kinetics of 99mTc-EDTA(Sn) and 99mTc- DTPA(Sn) at different temperatures (7, 22 and 37°C), no significant influence on the reduction step was found. The rate constant for complex formation, however, increased more rapidly with increased temperature for 99mTc-DTPA(Sn). At room temperature only a few minutes was required to achieve a high labelling yield with 99mTc-DTPA(Sn) whereas about 60 min was required for 99mTc-EDTA(Sn). Comparative biokinetic studies in rabbits showed that the maximum activity in kidneys is achieved after 12 min with 99mTc-EDTA(Sn) but already after 6 min with 99mTc-DTPA(Sn). The long-term disappearance of 99mTc-DTPA(Sn) from the kidneys is about five times faster than that for 99mTc-EDTA(Sn).

Rolling Resistance Calculation Procedure Using the Finite Element Method

2019 ◽  
Vol 48 (3) ◽  
pp. 224-248
Author(s):  
Pablo N. Zitelli ◽  
Gabriel N. Curtosi ◽  
Jorge Kuster
Keyword(s):  
Finite Element ◽  
Energy Dissipation ◽  
Rolling Resistance ◽  
Element Model ◽  
The Finite Element Method ◽  
Temperature Changes ◽  
Rubber Compounds ◽  
Different Temperatures ◽  
Materials Used ◽  
Account Temperature

ABSTRACT Tire engineers are interested in predicting rolling resistance using tools such as numerical simulation and tests. When a car is driven along, its tires are subjected to repeated deformation, leading to energy dissipation as heat. Each point of a loaded tire is deformed as the tire completes a revolution. Most energy dissipation comes from the cyclic loading of the tire, which causes the rolling resistance in addition to the friction force in the contact patch between the tire and road. Rolling resistance mainly depends on the dissipation of viscoelastic energy of the rubber materials used to manufacture the tires. To obtain a good rolling resistance, the calculation method of the tire finite element model must take into account temperature changes. It is mandatory to calibrate all of the rubber compounds of the tire at different temperatures and strain frequencies. Linear viscoelasticity is used to model the materials properties and is found to be a suitable approach to tackle energy dissipation due to hysteresis for rolling resistance calculation.

Core body temperature changes after sauna exposition in healthy subjects

2012 ◽  
Vol 26 (2) ◽  
Author(s):  
Joanna Pawlak ◽  
Paweł Zalewski ◽  
Jacek J. Klawe ◽  
Monika Zawadka ◽  
Anna Bitner ◽  
...  
Keyword(s):  
Body Temperature ◽  
Healthy Subjects ◽  
Core Body Temperature ◽  
Temperature Changes ◽  
Core Body

ADAPTATION OF WHITE MICE (MUS MUSCULUS) TO REPEATED COOLING

1967 ◽  
Vol 45 (3) ◽  
pp. 321-327 ◽  
Author(s):  
David M. Ogilvie
Keyword(s):  
Body Temperature ◽  
Rectal Temperature ◽  
Cold Exposure ◽  
Mus Musculus ◽  
Room Temperature ◽  
The Body ◽  
Progressive Decrease

The effects, on the body temperature of white mice, of repeated short exposures to cold were investigated using two methods of restraint. Animals held in a flattened posture became hypothermic at room temperature, cooled more than five times as fast at −10 °C as mice that could adopt a heat-conserving posture, and continued to cool for some time after they were removed from the cold. With repeated tests, cooling at room temperature decreased, and an improvement in re warming ability was observed. In addition, with lightly restrained mice, the fall in rectal temperature during cold exposure showed a progressive decrease, a phenomenon not observed with severely restrained animals.

scholarly journals Temperature dependence of the rigid amorphous fraction of poly(butylene succinate)

RSC Advances ◽  
2021 ◽  
Vol 11 (41) ◽  
pp. 25731-25737
Author(s):  
Maria Cristina Righetti ◽  
Maria Laura Di Lorenzo ◽  
Patrizia Cinelli ◽  
Massimo Gazzano
Keyword(s):  
Body Temperature ◽  
Temperature Dependence ◽  
Human Body ◽  
Room Temperature ◽  
Rigid Amorphous Fraction ◽  
Butylene Succinate ◽  
Amorphous Fraction ◽  
Human Body Temperature ◽  
Rigid Amorphous

At room temperature and at the human body temperature, all the amorphous fraction is mobile in poly(butylene succinate).

scholarly journals Temperature-Dependent Stimulated Emission Cross-Section in Nd3+:YLF Crystal

Materials ◽  
2021 ◽  
Vol 14 (2) ◽  
pp. 431
Author(s):  
Giorgio Turri ◽  
Scott Webster ◽  
Michael Bass ◽  
Alessandra Toncelli
Keyword(s):  
Cross Section ◽  
Cross Sections ◽  
Room Temperature ◽  
Radiative Decay ◽  
Emission Cross Section ◽  
Spectroscopic Properties ◽  
Stimulated Emission ◽  
Different Temperatures ◽  
Stimulated Emission Cross Section ◽  
Semi Empirical

Spectroscopic properties of neodymium-doped yttrium lithium fluoride were measured at different temperatures from 35 K to 350 K in specimens with 1 at% Nd3+ concentration. The absorption spectrum was measured at room temperature from 400 to 900 nm. The decay dynamics of the 4F3/2 multiplet was investigated by measuring the fluorescence lifetime as a function of the sample temperature, and the radiative decay time was derived by extrapolation to 0 K. The stimulated-emission cross-sections of the transitions from the 4F3/2 to the 4I9/2, 4I11/2, and 4I13/2 levels were obtained from the fluorescence spectrum measured at different temperatures, using the Aull–Jenssen technique. The results show consistency with most results previously published at room temperature, extending them over a broader range of temperatures. A semi-empirical formula for the magnitude of the stimulated-emission cross-section as a function of temperature in the 250 K to 350 K temperature range, is presented for the most intense transitions to the 4I11/2 and 4I13/2 levels.

Proteinase and phospholipase activities and development at different temperatures of yeasts isolated from bovine milk

2011 ◽  
Vol 78 (4) ◽  
pp. 385-390 ◽  
Author(s):  
Priscilla A Melville ◽  
Nilson R Benites ◽  
Monica Ruz-Peres ◽  
Eugenio Yokoya
Keyword(s):  
Dairy Products ◽  
Room Temperature ◽  
Bovine Milk ◽  
Raw Milk ◽  
Pathogenic Potential ◽  
Proteinase Production ◽  
Different Temperatures ◽  
Quality Of Milk ◽  
Means Of Transmission

The presence of yeasts in milk may cause physical and chemical changes limiting the durability and compromising the quality of the product. Moreover, milk and dairy products contaminated by yeasts may be a potential means of transmission of these microorganisms to man and animals causing several kinds of infections. This study aimed to determine whether different species of yeasts isolated from bovine raw milk had the ability to develop at 37°C and/or under refrigeration temperature. Proteinase and phospholipase activities resulting from these yeasts were also monitored at different temperatures. Five genera of yeasts (Aureobasidium sp., Candida spp., Geotrichum spp., Trichosporon spp. and Rhodotorula spp.) isolated from bovine raw milk samples were evaluated. All strains showed one or a combination of characteristics: growth at 37°C (99·09% of the strains), psychrotrophic behaviour (50·9%), proteinase production (16·81% of the strains at 37°C and 4·09% under refrigeration) and phospholipase production (36·36% of the isolates at 37°C and 10·9% under refrigeration), and all these factors may compromise the quality of the product. Proteinase production was similar for strains incubated at 37°C (16·81% of the isolates) and room temperature (17·27%) but there was less amount of phospholipase-producing strains at room temperature (15·45% of the isolates were positive) when compared with incubation at 37°C (36·36%). Enzymes production at 37°C by yeasts isolated from milk confirmed their pathogenic potential. The refrigeration temperature was found to be most efficient to inhibit enzymes production and consequently ensure better quality of milk. The viability of yeasts and the activity of their enzymes at different temperatures are worrying because this can compromise the quality of dairy products at all stages of production and/or storage, and represent a risk to the consumer.

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