scholarly journals Comparative study of neem leaf (Azadirachta indica) suspension and toltrazuril against coccidiosis in Sonali chicken

2020 ◽  
Vol 17 (2) ◽  
Author(s):  
R. Roy ◽  
M. H. Hasan ◽  
F. B. Aziz ◽  
R. Islam ◽  
S. Sarkar

Background: Coccidiosis is recognized as the parasitic disease with the greatest economic impact on poultry industries worldwide. Sonali chicken are commonly affected by coccidiosis in Bangladesh. Recently, the concerns about possible drug resistance have aroused great caution in the usage of drug in the animal industry. As an alternative herbal extracts are used and Neem leaves (Azadirachta indica) have anti-coccidial property. This study was conducted to evaluate the comparative efficacy of Neem leaves suspension and toltrazuril on coccidial load, blood constituents, growth performance of Sonali chicken infected with Eimeria tenella. Methods: The study was conducted in the laboratory and experimental shed under the department of physiology and pharmacology, HSTU, Dinajpur during, 2nd January to 3rd February, 2019. Eighty (80) Sonali chicken of seven days old were randomly divided into four groups named T0, T1 T2 and T3 and each group contained 20 birds. All groups were supplied E. tenella orally except T0 group and after 3 days T2 group was treated with Neem leaves suspension (5%) for 15 days and T3 groups was treated with toltrazuril (topzuril ®) solution (1 ml/lit) for 2 days. Results: Results showed that protozoal load decreased significantly (P<0.01) in T2 & T3 groups whereas increased significantly (P<0.01) in T0 and T1 group. The total erythrocyte count and hemoglobin in different treatment groups were similar and the differences were non-significant (P>0.05) statistically except total leukocyte count (TLC). The body weight of T0, T1, T2 and T3 group at day 30 were 432.65, 469.81, 548.81, 489.22 gm respectively which is statistically significant (P<0.01) and highest body weight gain was recorded from Neem leaves suspension treated group. Conclusion: Neem leaves suspension have significant effects on protozoal load, body weight and no significant effect on haematological parameters except TLC.

1970 ◽  
Vol 8 (1) ◽  
pp. 75-80 ◽  
Author(s):  
AR Das ◽  
M Mostofa ◽  
ME Hoque ◽  
S Das ◽  
AK Sarkar

The present study was investigated the comparative efficacy of extract of Neem (Azadirachta indica) and Metformin hydrochloride (Comet®) in respect of their hypoglycemic activity in Streptozotocin (STZ)-induced diabetic rats. Extract of Neem was administered @ 500 mg/kg body-weight (bwt) and 250 mg/kg bwt. Metformin hydrochloride @ 500 mg/kg bwt and 250 mg/kg daily orally for 21 days. Changes in the blood glucose level and body weight were measured and the results were compared statistically using Anova test. The extract of Neem leaves and Metformin hydrochloride showed significant (p<0.01) hypoglycemic effect and neem extracts at 250 mg/kg bwt showed more potent effects. The Neem extracts significantly (p<0.01) increased body weight @ 250 mg/kg. From this experiment it was observed that extracts of Neem leaves had hypoglycemic and body weight gain effect. For definite conclusion, details study is needed. DOI = 10.3329/bjvm.v8i1.8353 Bangl. J. Vet. Med. (2010). 8(1): 75-80


2014 ◽  
Vol 9 (10) ◽  
pp. 1934578X1400901 ◽  
Author(s):  
Qing Liu ◽  
Sang Hyun Kim ◽  
Seon Beom Kim ◽  
Yang Hee Jo ◽  
Eun Sil Kim ◽  
...  

The effect of the extract of Ligustrum lucidum fruits (LFE) and its major secoiridoid (LFS), (8- E)-nüzhenide, on obesity was investigated using high fat-diet (HFD)-induced C58BL/6J obese mice. LFE and LFS were administered at the doses of 300 mg/kg and 30 mg/kg, respectively, for 6 weeks. The anti-obesity activity was evaluated by measuring body weight, epididymal fat and metabolic plasma parameters. On Day 42, the body weight of the LFS-treated group was significantly lower compared with the HFD-treated group. Body weight gain was also reduced by 23.2% and 32.0% in the LFE- and LFS-treated groups, respectively, compared with the HFD group. In addition, the weight of the epididymal fat in the mice was significantly decreased in the HFD+LFS group. The food efficiency ratios (FERs) of the HFD+LFE and HFD+LFS groups were also lower compared with the HFD group with the same food intake. Metabolic parameters that had increased in the HFD group were decreased in the HFD+LFE and HFD+LFS groups. In particular, the increased triglyceride values were significantly reduced in the HFD+LFS group. These results show that treatment with LFE and LFS decreased HFD-induced obesity, mainly by improving metabolic parameters, such as fats and triglycerides. Therefore, LFE and LFS have potential benefits in regulation of obesity.


2013 ◽  
Vol 13 (2) ◽  
pp. 7-14
Author(s):  
Dedhi Yustendi ◽  
Dasrul Dasrul ◽  
Didy Rachmadi

The addition of katuk leaf meal (saurupus androgynus l.merr) in feeds on body weight gain and scrotal circumference  male ettawa grade goatsABSTRACT. This research was aimed to study the effect of addition of katuk leaf meal (Sauropus androgynus L. Merr)  in feed on body weight gain and scrotal circumference of male Ettawa grade goat. The research lasted for eight months, starting Agustus 2012 to Maret 2013, with feeding trial for two months. Twenty male Ettawa grade goats of 18 to 24 months old, were divided into 4 treatment groups. Treatment groups were added with 0% Katuk leaf meal (R0);  5% (R1);  10%  (R2) and 15%  (R3), with 5  goats in each replication. Treatment diets were feed in the morning and afternoon for 60 days. Weighing body weight and measuring scrotal circumference was done every week. Data were analyzed using analysis of variance (ANOVA) and if there was significantly different, the data were further tested using Duncan multiple range test. The result shows that the body weight gain of the treatment were, R0 (2,39 ± 0,43 kg); R1 (2,84 ± 0,36 kg); R2 (2,85 ± 0,20 kg) and R3 (3,42 ± 0,78 kg) respectively. Scrotal circumference were, R0 (0,74 ± 0,10 cm); R1 (1,24 ± 0,26 cm); R2 (1,26 ± 0,40 cm) dan R3 (1,32 ± 0,32 cm) respectively. The result of this research indicated that the addition of katuk leaf meal in feed had significant effects (P0,05) on body weight gain and scrotal circumference of Ettawa grade goat.


2020 ◽  
Vol 13 (1) ◽  
pp. 113-119
Author(s):  
K.K. Igwe ◽  
I.E. Otuokere ◽  
O. V. Ikpeazu

The leaves of Azadirachta indica plant was screened for haematological, toxic and serum enzyme activities in rats. Twenty rats were used and were grouped into 4 of 5 rats each. Group 1 was the negative control group administered distilled water. Groups 2, 3, and 4 were the treatment groups received 200, 400 and 800 mg/kg body weight of the A. indica extract respectively. The rats were dosed for 14 days, thereafter were sacrificed and blood collected by cardiac puncture for analysis. The effect of A. indica extract was checked on haematological parameters and serum enzymes activities. All results in treatment groups were compared with the normal control at statistical confidence of 95% (p<0.05). There was progressive reduction of haematological parameters as the dose of the extract increased from 200, 400, to 800 mg/kg body weight. Haematological parameters, PCV, RBC, Haemoglobin showed decrease value which was not statistically significant at (p<0.05). Total leukocyte count, showed progressively elevation by the extract though not statistically significant. Differential leukocyte count indicated very mild lymphocytosis neutropeania, monocytopeania and eosinopeania which were not statistically significant. Clinical biochemical parameters, A. indica extract demonstrated normal levels of the serum enzymes (AST, ALT and ALP) though there was slight decrease in a dose dependent fashion.Total protein was within normal range. The normal MCV, MCH and MCHC values suggests normocytic normochromic anaemic condition. The extract of A. indica is safe to blood cells, liver and kidney marker enzymes at dose < 800 mg/kg body weight.


2018 ◽  
Vol 3 (4) ◽  
pp. 521-528
Author(s):  
Mohammad Salahuddin ◽  
Zahirul Haque Khandaker ◽  
Mohammad Mohiuddin ◽  
Md Mostain Billah

An experiment was conducted in the poultry rearing unit of Sahjalal Animal Nutrition Field Laboratory, Bangladesh Agricultural University, Mymensingh for a period of 30 days by using 108 one week aged straight run Starbro broiler chicks to find out the effect of vitamin E and selenium as feed supplement for the performance of broiler. Chicks were distributed into 4 dietary treatment groups each having three replications (R1, R2, R3) and each replication contains 9 chicks. Dietary treatment groups were T0 (Control i.e. without supplemental vitamin E and Selenium), T1 (Control + 50 mg vitamin E 0.11 mg selenium per kg diet), T2 (Control + 100 mg vitamin and 0.22 mg Selenium per kg diet and T3 (Control + 150 mg vitamin E and 0.33 mg Selenium per kg diet). At end of the feeding trail the body weight of birds were 1238.28, 1231.85, 1272.59, and 1218.33 gm/bird in treatment groups T0, T1, T2 and T3 respectively which differ significantly (p<0.05) where highest body weight observed in T2 group . Body weight gain was highest in T2 (control+100mg vitamin E and 0.22 mg Selenium per kg diet) and lowest in T0 (control). Total Feed consumption during the experimental period was 2480.30, 2523.80, 2564.56 and 2555.39 g for T0, T1, T2 and T3 respectively. At 2nd and 3rd week of age, weekly feed conversion ratio were significantly (p<0.05) higher in T2 group than the other groups including control. Meat yield parameter of broilers showed significant (P<0.05) differences in dressing weight, breast weight and shank weight. Based on the above findings, the result suggest that supplementation of Vitamin E 100 mg and 0.22 mg Selenium per kg diet from ‘‘Lolyvit-ES’’ as a source of Vitamin E and Selenium may be used in broiler rations.Asian J. Med. Biol. Res. December 2017, 3(4): 521-528


2019 ◽  
Vol 20 (1) ◽  
pp. 62-66
Author(s):  
Magdy Amer

This study was performed on to evaluate the effect of some probiotic strains (Pediococcus acidophilus and Pedicoccus pentosaceus) on performance, blood picture and some biochemical parameters in serum of treated calves (10 weaned calves 90-115 kg). Calves were classified into 2 equal groups (each of 5 calves). The 1st group was served as the control group while the second group was given Maxboost® (20gm/head/day) in drinking water (after fermentation for 2-3 hours) for five months. Calves were weighed monthly to calculate the body weight gain till the end of the experiment whole blood weight and serum were collected from both groups at 1st, 2nd, 3rd, 4th and 5th month. Results revealed a significant increase in total body weight, body gain, total erythrocytes count, hemoglobin content, total leucocytes count, total protein and mean corpuscular hemoglobin. On the other hand, there were a significant decrease in serum aspartate transaminase (AST), serum alanine transaminase (ALT) and urea in pediococcus treated group compared to the control one.


2016 ◽  
Vol 5 (1) ◽  
pp. 35-40 ◽  
Author(s):  
F Akter ◽  
MMR Howlader ◽  
MK Hossain ◽  
MMI Hasan ◽  
S Islam ◽  
...  

This study was carried out to evaluate the effects of supplementation of commercial layer feed on body weight, egg production and haematological profile of the laying ducks rearing under the rural condition of Bangladesh. Twenty indigenous ducks (Khaki Campbell x Local duck) of 24 weeks old was selected from a farm and randomly divided into four equal groups (n=5) and numbered as group T0, T1, T2 & T3. The different amount of feed was supplied into four groups for three months. The all four groups (T0, T1, T2 and T3) were fed with routine feeding in scavenging condition. But T1 group supplemented with 120 gm, T2 group 60 gm and T3 group 30 gm of commercial feed. Significant differences were found in both egg production and haematological profile of ducks in compared to control group. Egg production was significantly (P<0.01) higher in T1 group compared to other groups. During the study the body weight gain were shown the same pattern being significantly (P<0.05) higher in T1 group compared to T0, T2 and T3 groups. On the other hand, the values of total erythrocyte count (TEC), total leukocyte count (TLC), haemoglobin content (Hb) and packed cell volume (PCV) increased significantly (P<0.05) in the groups of T1 and T2 compared to the control group (T0). But the value of MCV, MCH and MCHC of T1, T2 & T3 groups decreased significantly (P<0.05) than that of the control group. Results of the present study revealed that the amount of supplementation of commercial layer feeds was very important for improving the haematological profile and egg production of ducks. So, the additional commercial layer feed supplementation may be beneficial for duck farming.International Journal of Natural Sciences (2015), 5(1) 35-40


2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Ahmed Abdel-Megeed ◽  
Arifa Tahir

The present study was conducted to reduce phosphorus pollution from broilers waste by supplementing phytase enzyme in broilers fee. Two hundred two-week-old broilers (Hubbard) were selected and randomly allocated to three dietary treatment groups, one control group (without phytase) and two trial groups (group A with 300 U/kg phytase and group B with 600 U/kg phytase). Each group was composed of 5 replicates with 10 chicks. Broilers fed the control diet (without phytase) gained weight slower (P< 0.05) than the other treatment groups. A significant increase in body weight gain of group A (28.00 ± 2.97) and group B (29.75 ± 3.45) was observed as compared to control group (26.75 ± 2.78). The feed intake of the birds fed the diets containing microbial phytase 600 U/kg was the highest. Phytase significantly (P> 0.05) reduces excreta P and Ca level. Phytase addition did not affect excreta pH. The presence of phytase in feed mixtures significantly (P> 0.05) improves the body weight gain and feed intake of broiler chickens.


2001 ◽  
Vol 64 (11) ◽  
pp. 1780-1784 ◽  
Author(s):  
ROGER B. HARVEY ◽  
THOMAS S. EDRINGTON ◽  
LEON F. KUBENA ◽  
GEORGE E. ROTTINGHAUS ◽  
JAMES R. TURK ◽  
...  

In two studies, the effects of moniliformin (M)-contaminated diets from Fusarium fujikuroi culture material on growing barrows were evaluated. In the first study, six barrows (three replicates of two each, mean body weight = 17.8 kg) per group (four groups; 24 barrows total) were fed diets calculated to contain 0 mg M/kg feed (control); 25 mg M/kg feed; 50 mg M/kg feed; or 100 mg M/kg feed for 28 days. In the second study, the same experimental design and numbers of barrows (mean body weight = 15.3 kg) were used, and diets were formulated to contain 0 mg M/kg feed (control); 50 mg M/kg feed; 100 mg M/kg feed; or 200 mg M/kg feed. Diets of 100 mg or 200 mg M/kg feed reduced body weight, body weight gain, and feed consumption. Serum biochemical analytes were affected by 100 to 200 mg M/kg feed. Hematologic values were affected by 50, 100, and 200 mg M/kg feed. In the first study, one barrow in the 100 mg M-treated group died, and in the second study, one barrow died in the 100 mg M-treated group, and five barrows died in the 200 mg M-treated group. Relative heart weight was increased in the 200 mg M-treated barrows, yet tissues from organs collected from treatment groups were generally histologically unimpressive. The most consistent sign of M toxicity in barrows appeared to be death induced within 2 to 5 days by 100 to 200 mg M/kg feed.


2014 ◽  
Vol 84 (1-2) ◽  
pp. 5-11 ◽  
Author(s):  
Eun Y. Jung ◽  
Sung C. Jun ◽  
Un J. Chang ◽  
Hyung J. Suh

Previously, we have found that the addition of L-ascorbic acid to chitosan enhanced the reduction in body weight gain in guinea pigs fed a high-fat diet. We hypothesized that the addition of L-ascorbic acid to chitosan would accelerate the reduction of body weight in humans, similar to the animal model. Overweight subjects administered chitosan with or without L-ascorbic acid for 8 weeks, were assigned to three groups: Control group (N = 26, placebo, vehicle only), Chito group (N = 27, 3 g/day chitosan), and Chito-vita group (N = 27, 3 g/day chitosan plus 2 g/day L-ascorbic acid). The body weights and body mass index (BMI) of the Chito and Chito-vita groups decreased significantly (p < 0.05) compared to the Control group. The BMI of the Chito-vita group decreased significantly compared to the Chito group (Chito: -1.0 kg/m2 vs. Chito-vita: -1.6 kg/m2, p < 0.05). The results showed that the chitosan enhanced reduction of body weight and BMI was accentuated by the addition of L-ascorbic acid. The fat mass, percentage body fat, body circumference, and skinfold thickness in the Chito and Chito-vita groups decreased more than the Control group; however, these parameters were not significantly different between the three groups. Chitosan combined with L-ascorbic acid may be useful for controlling body weight.


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