scholarly journals Maternal outcome in pregnant women with anaemia

2018 ◽  
Vol 17 (3) ◽  
pp. 446-454 ◽  
Author(s):  
Neerja Singal ◽  
Geetanjali Setia ◽  
Bal Krishan Taneja ◽  
Kiran Kumar Singal

Background: Anaemia in pregnancy is one of the most important and common public health problem not only in India but also in most of the South East Asian countries. Anaemia is the most common nutritional deficiency disorder in the world. There is predominance of iron deficiency anaemia (nutritional anaemia). In pregnancy, it is one of the leading causes responsible for maternal morbidity and mortality.Objective: To find out the maternal outcome in pregnant women with anaemia at MMIMSR during the study period with special reference to the severity of the disease.Methods: The study was conducted in Department of Obstetrics and Gynaecology, MMIMSR, Mullana, Ambala(India). The study was carried out between the period of october 2012 to September 2014.A total of 200 cases of moderate and severe anaemia were included in the study on the basis of simple random sampling method and 200 cases of non anaemic subjects were included to serve as controls for the anaemic group, during the study period. Hb gm/dl was taken as criteria for deciding anaemia cases and also to classify them according to the severity. Cases were classified according to WHO criteria.Results: Out of 200 cases of anaemia, 70% were moderately anaemic (Hb 7 – 9.9gm/dl) and 30% were severly anaemic (Hb < 7gm/dl). Microcytic hypochromic type of anaemia (82.5%) was more prevalent suggesting nutritional inadequacies as cause of anaemia. Higher incidence of preterm (17%), PPH (7.5%), maternal morbidity (14.5%) was found in anaemic group as compared to non anaemic controls.Conclusion: Anaemia in pregnancy has adverse maternal outcome in the form of maternal morbidity, preterm labour, and increased incidence of operative delivery.Bangladesh Journal of Medical Science Vol.17(3) 2018 p.446-454

2018 ◽  
Vol 17 (4) ◽  
pp. 583-592 ◽  
Author(s):  
Neerja Singal ◽  
Geetanjali Setia ◽  
Bal Krishan Taneja ◽  
Kiran Kumar Singal

Background: Anaemia in pregnancy is one of the most important and common public health problem not only in India but also in most of the South East Asian countries. Anaemia is the most common nutritional deficiency disorder in the world. There is predominance of iron deficiency anaemia (nutritional anaemia). In pregnancy, it is one of the leading causes responsible for maternal and perinatal morbidity and mortality.Objective: To find out the risk factors associated with anaemia in pregnant women at MMIMSR during the study period with special reference to the severity of the disease.Methods: The study was conducted in Department of Obstetrics and Gynaecology, MMIMSR, Mullana, Ambala. The study was carried out between the period of october 2012 to September 2014.A total of 200 cases of moderate and severe anaemia were included in the study on the basis of simple random sampling method and 200 cases of non anaemic subjects were included to serve as controls for the anaemic group, during the study period. Hb gm/dl was taken as criteria for deciding anaemia cases and also to classify them according to the severity. Cases were classified according to WHO criteria.Results: Out of 200 cases of anaemia, 70% were moderately anaemic (Hb 7 – 9.9gm/dl) and 30% were severly anaemic (Hb < 7gm/dl). Microcytic hypochromic type of anaemia (82.5%) was more prevalent suggesting nutritional inadequacies as cause of anaemia.Conclusion: In the present study maternal illiteracy, low SES, inadequate antenatal care, close birth spacing, poor nutrition were all risk factors for anaemia in pregnancy Microcytic hypochromic type of anaemia (82.5%) was more prevalent suggesting nutritional inadequacies as cause of anaemia.Bangladesh Journal of Medical Science Vol.17(4) 2018 p.583-592


2018 ◽  
Vol 18 (1) ◽  
pp. 63-72 ◽  
Author(s):  
Neerja Singal ◽  
Bal Krishan Taneja ◽  
Geetanjali Setia ◽  
Kiran Kumar Singal

Objective: To find out the situation and causes of anaemia in pregnant women at MMIMSR during the study period with special reference to the severity of the disease and to find out foetal outcome in pregnant women with anaemia. Methods: The study was conducted in Department of Obstetrics and Gynaecology, MMIMSR, Mullana, Ambala(India). The study was carried out between the period of october 2012 to September 2014.A total of 200 cases of moderate and severe anaemia were included in the study on the basis of simple random sampling method and 200 cases of non anaemic subjects were included to serve as controls for the anaemic group, during the study period. Hb gm/dl was taken as criteria for deciding anaemia cases and also to classify them according to the severity. Cases were classified according to WHO criteria. Results: Out of 200 cases of anaemia, 70% were moderately anaemic (Hb 7 – 9.9gm/dl) and 30% were severly anaemic (Hb < 7gm/dl). Microcytic hypochromic type of anaemia (82.5%) was more prevalent suggesting nutritional inadequacies as cause of anaemia. Adverse foetal outcome in the form of preterm birth (17%), still birth (3.5%), low birth weight babies (27.5%), neonatal morbidity (23.3%) was more in the anaemic group than non anaemic controls Conclusion: Anaemia in pregnancy has adverse foetal outcome in the form of decreased birth weight, increased perinatal morbidity and mortality. Bangladesh Journal of Medical Science Vol.18(1) 2019 p.63-72


2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Temitope Elizabeth Adeboye ◽  
Akinkunmi Paul Okekunle

Abstract IntroductionAnaemia in pregnancy is a global public health problem and about half of all anaemia cases among pregnant women in developing countries are attributable to iron (Fe) deficiency. Perhaps, nutritional knowledge on the vitality of Fe-containing foods among pregnant women is lacking. In the light of the perpetually high burden of anaemia in pregnancy in Nigeria, we conducted a study to assess the knowledge of Fe-containing foods among pregnant women in Lagos, Nigeria.Materials and MethodsFour hundred and thirty two (432) pregnant women in the 2nd and 3rd trimester of pregnancy (across eight Primary Health Centers in a local government area) from Lagos Nigeria identified through multi-stage sampling method completed validated semi-structured questionnaires on socio-demographic characteristic and knowledge of Fe-containing foods using a validated 10-question knowledge scale (designed by nutrition experts) measured on a 2-point scale. Knowledge score (KS) was categories as poor (2 test was used to evaluate the association between age groups, education, marital status and knowledge of Fe-containing foods (at P < 0.05).ResultsMean age of all respondents was 28.5 ± 4.6years and 43.3% were below 28years. Mean gestational age was 31.3 ± 4.1weeks, 6.5% and 1.9% reported having a primary formal education only and never married respectively. Mean knowledge score of all respondents was 6.7 ± 2.2 and 34.7% had poor KS about Fe-containing foods. While age of respondents was insignificantly associated with KS, proportion of pregnant women who had good KS was significantly higher (χ2 = 6.6, P = 0.01) among those with at least a college education (66.8%) compared to their counterpart having at a primary formal education only (42.9%). In addition, proportion of respondents with poor KS was significantly lower (χ2 = 9.9, P = 0.007) among those ever married (34.8%) compared to respondents who never married (75.0%).ConclusionAside nutrition education, the vitality of adequate formal education for women prior to pregnancy and care giving roles cannot be undermined in advancing the knowledge of women on anemia and alleviating the burden anaemia in pregnancy in developing countries.


2019 ◽  
Vol 3 (2) ◽  
pp. p47
Author(s):  
Isah Balarabe Adamu ◽  
Azeez Shareef Ayotunde ◽  
Kehinde Joseph Awosan ◽  
Edzu Usman Yunusa

Background: Anaemia in pregnancy remains a major cause of maternal death in Sub-Saharan Africa, and it mostly results from a deficiency of iron and folate.Objectives: To determine the prevalence of anemia and the factors associated with it among pregnant women in Bunza, Nigeria. Materials and Method: A cross-sectional study conducted among 327 pregnant women attending ANC in General Hospital Bunza, Kebbi State, Nigeria. Data were collected using a pretested questionnaire. Estimation of packed cell volume and RDT were alsodone for the participants; datawereanalysedusing IBMSPSS version 20. Results: The mean packed cell volume of the respondents was 30.7, with a SD 3.7 and majority of the respondents were having anemia 240(75.7%). Level of education of the respondents and their spouses, age at first pregnancy, spouses’ occupation, and the trimester at which the respondents booked were found to be significant p ?0.05for anemic status. Conclusion: The prevalence of anemia in pregnancy is high among pregnant women in Bunza, Nigeria, with the factors associated with it being the levels of education of the woman and that of her spouse, spouse’s occupation, having the first pregnancy before the age of 19 years, and late booking. Recommendations: Anemia in Pregnancy should be considered a public health problem in the LGA and state in general and girl child education should be given priority as a long term measure.


Author(s):  
Geetanjali Kanwar ◽  
Shweta Rani Prasad ◽  
Rekha Ratnani

Background: Anemia in pregnancy is an important public health problem in developing countries like India. Anemia results in poor pregnancy outcome and also affects fetal outcome. The present study was conducted to asses maternal and fetal outcome in relation anemia. Aim and objectives of the study was to determine incidence, risk factors and maternal-fetal outcome of anemia in the admitted pregnant women attending obstetrics and gyanecology department, shanakarcharya institute of medical sciences, Bhilai.Methods: This is retrospective observational study conducted among pregnant women admitted in labor room over a period of one year after getting approval from the institutional ethical committee.Results: Out of total 1503 delivery during study period 675 patients were found to be anaemic which gives incidence of 44.5%. Most the pregnant women were moderately anaemic i.e. 50.96% followed by mild (45.04%) and severe (4%) repectively. Among the pregnant women most common type of anaemia is Iron deficiency anaemia (69.65%) followed by Sickle cell anaemia (15.4%). In the present study,90.4% of subject received oral iron, 26.9% received parenteral iron and 19.4% received blood transfusion. Common maternal outcome related to anemia found to be low birth weight (25.2%) followed by premature delivery (22.96%) and fetal outcome in anemic mother in the form of preterm (22.9%) followed by NICU admission (14.37%) and FGR (8.6%).Conclusions: Anemia being one of the most important cause of poor feto maternal outcome should be treated preconceptionaly. There is a need of health education programmes and adequate intake of iron rich diet during pregnancy, to be strengthened for safe maternal and foetal outcomes.


Author(s):  
Esther Ijeoma Nonye-Enyidah ◽  
Basil Omieibi A. Altraide ◽  
Awopola I. Jumbo

Background: Anaemia in pregnancy is the commonest haematological condition seen in pregnant women in most developing countries. It is a global public health problem causing maternal and fetal morbidity and mortality. Objective was to determine the prevalence of anaemia and associated socio-demographic factors among pregnant women at booking at Rivers State University Teaching Hospital (RSUTH).Methods: A retrospective study conducted from 1st January, 2015 to 31st December, 2020 at the antenatal clinic (ANC) of RSUTH. The laboratory records of 9990 pregnant women who booked for antenatal care were retrieved and reviewed. This included the socio-demographic characteristics and routine investigations. Data was extracted, coded and analyzed using the IBM statistical package for social sciences (SPSS) version 23.0 (Armonk, NY). P value <0.05 was considered statistically significant.Results: Total number of women who booked for antenatal care was 9990 women. Of this, 8635 women were anaemic giving a prevalence rate of 86.4%. Mild anaemia was seen in 7061 (70.68%); 1546 (15.48%) had moderate anaemia and 28 (0.28%) had severe anaemia. Of 8635 (86.4%) women who were anaemic, 1647 (19.07%), 5036 (58.32%) and 1952 (22.61%) were seen in the first, second and third trimesters respectively. Mean and modal packed cell volume (PCV) were 29±3.1% and 29% respectively. The range of PCV was 18-42%. Mean age was 31±4.7 years and age range was 15-48 years. Modal parity was zero. Nulliparous and multiparous women accounted for 3586 (35.9%) and 3751 (37.5%) of the women respectively. There was a significant correlation between anaemia and age, parity, level of education, occupation and genotype at booking.Conclusions: The prevalence of anaemia was unacceptably high. There is need for education on anaemia at the antenatal clinics and close monitoring of the interventional measures put in place to prevent anaemia in pregnancy, in order to improve the pregnancy outcome.


Author(s):  
Prashant D. ◽  
Jaideep K. C. ◽  
Girija A. ◽  
Mallapur M. D.

Background: Anaemia in pregnancy accounts for one fifth of maternal deaths worldwide and is a major factor responsible for low birth weight. In India, 16% of maternal deaths are attributed to anaemia. Prevalence of anaemia is higher among pregnant women and it persists in India despite of the availability of effective, low-cost interventions for prevention and treatment. The objective was to study the prevalence of anaemia among rural pregnant women and also to study various socio-demographic factors associated with anaemia in pregnancy.Methods:A cross-sectional study was carried out between February to July 2016 amongst 400 pregnant women residing in PHC Handignur were interviewed using pre-tested pre-designed questionnaire. Hb percentage was estimated by using Sahli’s method.Results: Total of 291 pregnant women were found out to have Hb levels less than 11 gm%. 9 pregnant women were found to have severe anaemia, 149 had moderate anaemia, 133 had mild anaemia. Factors such as literacy status, open air defecation were found to be significantly associated with the prevalence of anaemia in pregnancy.Conclusions:Prevalence of anaemia among the pregnant women was found to be 72.75%. Early detection and effective management of anaemia in pregnancy can contribute substantially to reduction in maternal mortality. 


2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Gayani Shashikala Amarasinghe ◽  
Thilini Chanchala Agampodi ◽  
Vasana Mendis ◽  
Krishanthi Malawanage ◽  
Chamila Kappagoda ◽  
...  

Abstract Background The Sustainable development goals, which focus strongly on equity, aim to end all forms of malnutrition by 2030. However, a significant cause of intergenerational transfer of malnutrition, anaemia in pregnancy, is still a challenge. It is especially so in the low- and middle-income settings where possible context-specific aetiologies leading to anaemia have been poorly explored. This study explores the prevalence of etiological factors significantly contributing to anaemia in pregnancy in Sri Lanka, a lower-middle-income country with a high prevalence of malnutrition albeit robust public health infrastructure. Methods All first-trimester pregnant women registered in the public maternal care programme in the Anuradhapura district from July to September 2019 were invited to participate in Rajarata Pregnancy Cohort (RaPCo). After a full blood count analysis, high-performance liquid chromatography, peripheral blood film examination, serum B12 and folate levels were performed in anaemic participants, guided by an algorithm based on the red cell indices in the full blood count. In addition, serum ferritin was tested in a random subsample of 213 participants. Anaemic women in this subsample underwent B12 and folate testing. Results Among 3127 participants, 14.4% (95%CI 13.2–15.7, n = 451) were anaemic. Haemoglobin ranged between 7.4 to 19.6 g/dl. 331(10.6%) had mild anaemia. Haemoglobin ≥13 g/dl was observed in 39(12.7%). Microcytic, normochromic-normocytic, hypochromic-normocytic and macrocytic anaemia was observed in 243(54%), 114(25.3%), 80(17.8%) and two (0.4%) of full blood counts in anaemic women, respectively. Microcytic anaemia with a red cell count ≥5 * 106 /μl demonstrated a 100% positive predictive value for minor haemoglobinopathies. Minor hemoglobinopathies were present in at least 23.3%(n = 105) of anaemic pregnant women. Prevalence of iron deficiency, B12 deficiency and Southeast Asian ovalocytosis among the anaemic was 41.9% (95%CI 26.4–59.2), 23.8% (95%CI 10.6–45.1) and 0.9% (95%CI 0.3–2.3%), respectively. Folate deficiency was not observed. Conclusion Even though iron deficiency remains the primary cause, minor hemoglobinopathies, B 12 deficiency and other aetiologies substantially contribute to anaemia in pregnancy in this study population. Public health interventions, including screening for minor hemoglobinopathies and multiple micronutrient supplementation in pregnancy, should be considered in the national programme for areas where these problems have been identified.


F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 223
Author(s):  
Gayani Amarasinghe ◽  
Vasana Mendis ◽  
Thilini Agampodi

Background: Anaemia in pregnancy, which can lead to adverse maternal and fetal outcomes, is a significant global health problem. Despite Sri Lanka’s strong public health system and commitment towards prevention, maternal anaemia remains a major problem in the country. While prevention is focused on iron deficiency, detailed etiological studies on this topic are scarce. Moreover, estimates of socio demographic and economic factors associated with anaemia in pregnancy, which can provide important clues for anaemia control, are also lacking. This study aims to evaluate the hemoglobin distribution, spatial distribution, etiology and associated factors for anaemia in pregnant women in Anuradhapura, Sri Lanka. Methods: This is a cross sectional study of pregnant women in their first trimester registered for antenatal care from July to September 2019 in the Anuradhapura district. The minimal sample size was calculated to be 1866. Initial data collection has already been carried out in special field clinics for pregnant women between June to October 2019. An interviewer-administered questionnaire, a self-completed dietary questionnaire and an examination checklist were used for data collection. In addition, all participants underwent complete blood count testing. Further investigations are being conducted for predicting the etiology of anaemia based on a developed algorithm (such as high-performance liquid chromatography [HPLC] and peripheral blood film analysis). Discussion: Being the largest study on anaemia during pregnancy in a single geographical area in Sri Lanka, this study will provide important clues about geographical clustering of anaemia cases with similar etiology, associated factors and etiologies which would help to develop interventions to improve the health of pregnant women in the area. The possibility of selection bias is a potential limitation associated with the study design.


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