Deep Cavitand Calixarene–Solubilized Fullerene as a Potential Photodynamic Agent

Fullerene has attracted much attention in biomedical research due to its unique physical and chemical properties. However, the hydrophobic nature of fullerene is limited to deploy in the body, given that the biofluids are mainly water. In this study, a water-soluble supramolecular nanoformulation based on a deep cavitand calixarene (SAC4A) and fullerene is developed to overcome the hydrophobicity of fullerene and is used as a potential photodynamic agent. SAC4A solubilizes fullerene very well with a simple grinding method. The significantly increased water solubility of fullerene enables efficient activation of reactive oxygen species. The host–guest strategy to solubilize fullerene can not only provide a new method to achieve water solubility but also expand the biomedical applications of fullerene.

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TO THE QUESTION OF INDUSTRIAL AEROSOL CONTROL IN THE PROCESSING OF BLISTER COPPER

10.31089/978-5-6042929-2-1-2021-1-185-190 ◽

2021 ◽

Author(s):

O.G. Drugova ◽

◽

A.A. Fedoruk ◽

T.N. Shtin

Keyword(s):

Chemical Properties ◽

The Body ◽

Industrial Control ◽

Silicon Iron ◽

Carcinogenic Effect ◽

Copper Zinc ◽

Toxic Potential ◽

Physical And Chemical ◽

Industrial Aerosol ◽

And Chemical Properties

Abstract. Due to the predominance of PM1 particles in the air samples, the following metals were found in the aerosol: copper, zinc, silicon, iron, lead, sulfur, arsenic, aluminum, antimony, tin, magnesium, cadmium and several other metals. The content of sulfates was significantly noted. These physical and chemical properties show a considerable toxic potential of industrial aerosol. The MPC of lead, sulfur and silicon dioxides, as well as nitrogen oxides and formaldehyde were detected in the working air. Meanwhile, copper, zinc, and iron did not exceed their MPC. Moreover, an underestimation of the aerosol was observed within the framework of industrial control. It has been found that the aerosol components may have an irritating, reprotoxic, allergenic, and carcinogenic effect on the body. Further consideration of the dispersed and chemical composition of the aerosol is required to determine the concentration of identified substances in the working air and the limiting components determining its biological effect.

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On eccentricity-based topological descriptors of water-soluble dendrimers

Zeitschrift für Naturforschung C ◽

10.1515/znc-2018-0123 ◽

2018 ◽

Vol 74 (1-2) ◽

pp. 25-33 ◽

Cited By ~ 11

Author(s):

Zahid Iqbal ◽

Muhammad Ishaq ◽

Adnan Aslam ◽

Wei Gao

Keyword(s):

Molecular Structure ◽

Chemical Properties ◽

Topological Indices ◽

Water Soluble ◽

Connectivity Index ◽

Topological Descriptors ◽

Physical And Chemical Properties ◽

Eccentric Connectivity Index ◽

Physical And Chemical ◽

And Chemical Properties

AbstractPrevious studies show that certain physical and chemical properties of chemical compounds are closely related with their molecular structure. As a theoretical basis, it provides a new way of thinking by analyzing the molecular structure of the compounds to understand their physical and chemical properties. The molecular topological indices are numerical invariants of a molecular graph and are useful to predict their bioactivity. Among these topological indices, the eccentric-connectivity index has a prominent place, because of its high degree of predictability of pharmaceutical properties. In this article, we compute the closed formulae of eccentric-connectivity–based indices and its corresponding polynomial for water-soluble perylenediimides-cored polyglycerol dendrimers. Furthermore, the edge version of eccentric-connectivity index for a new class of dendrimers is determined. The conclusions we obtained in this article illustrate the promising application prospects in the field of bioinformatics and nanomaterial engineering.

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Carbon Dots: Synthesis, Properties and Biomedical Applications

Journal of Materials Chemistry B ◽

10.1039/d1tb01077h ◽

2021 ◽

Author(s):

Guili Ge ◽

Lin Li ◽

Dan Wang ◽

Mingjian Chen ◽

Zhaoyang Zeng ◽

...

Keyword(s):

Carbon Dots ◽

Biomedical Applications ◽

Chemical Properties ◽

Physical And Chemical Properties ◽

Synthesis Properties ◽

New Type ◽

Low Toxicity ◽

Good Biocompatibility ◽

Physical And Chemical ◽

And Chemical Properties

Carbon dots (CDs) are a new type of carbon nanomaterial that have unique physical and chemical properties, good biocompatibility, low toxicity, easy surface functionalization, making them widely used in biological...

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Biocompatibility in regenerative nanomedicine

Nanomedicine ◽

10.2217/nnm-2019-0140 ◽

2019 ◽

Vol 14 (20) ◽

pp. 2763-2775 ◽

Cited By ~ 2

Author(s):

Fatih Zor ◽

Fatma Nurefsan Selek ◽

Giuseppe Orlando ◽

David F Williams

Keyword(s):

Chemical Properties ◽

The Body ◽

Common Word ◽

Target Cells ◽

Physical And Chemical Properties ◽

Foreign Material ◽

Biomaterial Science ◽

Physical And Chemical ◽

And Chemical Properties

Biocompatibility is a very common word that is used within biomaterial science and used for description of the interactions between the foreign material and the body. However, the meaning of biocompatibility as well as the mechanisms that collectively constitutes is still unclear. With the advance of nanotechnology, new concerns have been observed related to biocompatibility of these biomaterials. Due to their small size and variability of their physical and chemical properties, nanoparticles’ (NP) distribution within the body and interactions with the target cells and tissues are highly variable. Here, we tried to provide an overview about NPs, the concept of biocompatibility and biocompatibility-related issues in nanomedicine and several different NPs.

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Current Progress in Cross-Linked Peptide Self-Assemblies

International Journal of Molecular Sciences ◽

10.3390/ijms21207577 ◽

2020 ◽

Vol 21 (20) ◽

pp. 7577

Author(s):

Noriyuki Uchida ◽

Takahiro Muraoka

Keyword(s):

Self Assembly ◽

Three Dimensional ◽

Chemical Properties ◽

Water Soluble ◽

Cross Linking ◽

Physical And Chemical Properties ◽

Cell Scaffold ◽

Scaffold Materials ◽

Physical And Chemical ◽

And Chemical Properties

Peptide-based fibrous supramolecular assemblies represent an emerging class of biomaterials that can realize various bioactivities and structures. Recently, a variety of peptide fibers with attractive functions have been designed together with the discovery of many peptide-based self-assembly units. Cross-linking of the peptide fibers is a key strategy to improve the functions of these materials. The cross-linking of peptide fibers forming three-dimensional networks in a dispersion can lead to changes in physical and chemical properties. Hydrogelation is a typical change caused by cross-linking, which makes it applicable to biomaterials such as cell scaffold materials. Cross-linking methods, which have been conventionally developed using water-soluble covalent polymers, are also useful in supramolecular peptide fibers. In the case of peptide fibers, unique cross-linking strategies can be designed by taking advantage of the functions of amino acids. This review focuses on the current progress in the design of cross-linked peptide fibers and their applications.

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Quantification of Hydrophobic Recovery and Temporal Bonding in Polydimethylsiloxane

The Journal of Undergraduate Research at the University of Illinois at Chicago ◽

10.5210/jur.v1i1.7455 ◽

2007 ◽

Vol 1 (1) ◽

Author(s):

N. Zachariah ◽

J. S. Mohammed ◽

D. T. Eddington

Keyword(s):

Chemical Properties ◽

Time Frame ◽

Physical And Chemical Properties ◽

Methyl Group ◽

Plasma Activation ◽

Micro Fluidics ◽

Hydrophobic Recovery ◽

Hydrophobic Nature ◽

Physical And Chemical ◽

And Chemical Properties

Polydimethylsiloxane is used ubiquitously in micro fluidics both as a mold and as a device in and of itself due to the polymer's distinct physical and chemical properties. This elastomer is intrinsically hydrophobic due to the methyl group that is a part of its chemical backbone. Hydrophilicity is induced by plasma activation but is short lived as this elastomer regains its hydrophobic nature as uncrosslinked PDMS chains start to reorient back to the surface. Quantifying the bonding time frame will prove invaluable for any and all research applications that revolve around PDMS.

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2D Materials for Environment, Energy, and Biomedical Applications

Journal of Biomedical Research & Environmental Sciences ◽

10.37871/jbres1340 ◽

2021 ◽

Vol 2 (10) ◽

pp. 977-984

Author(s):

Divya Chauhan ◽

Mohammad Ashfaq ◽

Neetu Talreja ◽

Ramalinga Viswanathan Managalraja

Keyword(s):

Electronic Structure ◽

Biomedical Applications ◽

Short Communication ◽

Biomedical Application ◽

2D Materials ◽

Chemical Properties ◽

Physical And Chemical Properties ◽

Energy Environment ◽

Physical And Chemical ◽

And Chemical Properties

Recently 2D materials are booming in the field of energy, environment, and biomedical application. Incorporation of metal/non-metal within 2D materials significantly influences the physical and chemical properties, making them intriguing materials for various applications. The advancement of 2D material requires strategic modification by manipulating the electronic structure, which remains a challenge. Herein, we describe 2D materials for the environment, energy, and biomedical application. A predominant aim of this short communication is to summarize the literature on the advanced environment, energy, and biomedical application (especially COVID-19).

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WILDIERS' BIOS AND THE LACTIC ACID BACTERIA: THE RELATION OF BIOS TO THE WATER-SOLUBLE B-VITAMINS

Canadian Journal of Research ◽

10.1139/cjr38b-005 ◽

1938 ◽

Vol 16b (2) ◽

pp. 46-53 ◽

Cited By ~ 3

Author(s):

Blythe Alfred Eagles ◽

Olga Okulitch ◽

Arthur Stephen Kadzielawa

Keyword(s):

Lactic Acid ◽

Lactic Acid Bacteria ◽

Chemical Properties ◽

Water Soluble ◽

Vitamin B ◽

Physical And Chemical Properties ◽

Heat Stable ◽

Physical And Chemical ◽

Growth Of Animals ◽

And Chemical Properties

The influence of three distinct activators prepared from tomatoes, yeast, or liver, on the metabolism of two species of lactic acid bacteria has been studied. One of these activators is Bios II A, and the other two have been shown to be components constituting Bios II B. On the basis of their physical and chemical properties, it is suggested that the growth stimulants required by the lactic acid bacteria are identical with certain of the heat-stable accessory food factors of the Vitamin-B complex essential for the growth of animals.

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BIOMEDICAL APPLICATIONS OF ELECTROSPUN NANOFIBERS

Surface Review and Letters ◽

10.1142/s0218625x20300014 ◽

2020 ◽

Vol 27 (11) ◽

pp. 2030001

Author(s):

ZHANG YANCONG ◽

DOU LINBO ◽

MA NING ◽

WU FUHUA ◽

NIU JINCHENG

Keyword(s):

Biomedical Applications ◽

Three Dimensional ◽

Chemical Properties ◽

Electrospun Nanofibers ◽

High Porosity ◽

Nanofiber Diameter ◽

Surface Microscopy ◽

Different Shapes ◽

Physical And Chemical ◽

And Chemical Properties

Electrospun technology is a simple and flexible method for preparation of nanofiber materials with unique physical and chemical properties. The nanofiber diameter is adjustable from several nanometers to few microns during the preparation. Electrospun nanofiber materials are easy to be assembled into different shapes of three-dimensional structures. These materials exhibit high porosity and surface area and can simulate the network structures of collagen fibers in a natural extracellular matrix, thereby providing a growth microenvironment for tissue cells. Electrospun nanofibers therefore have extensive application prospects in the biomedicine field, including in aerospace, filtration, biomedical applications, and biotechnology. Nanotechnology has the potential to revolutionize many fields, such as surface microscopy, silicon fabrication, biochemistry, molecular biology, physical chemistry, and computational engineering, while the advent of nanofibers has increased the understanding of nanotechnology among academia, industry, and the general public. This paper mainly introduces the application of nanofiber materials in tissue engineering, drug release, wound dressing, and other biomedicine fields.

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Crosslinking Collagen Constructs: Achieving Cellular Selectivity Through Modifications of Physical and Chemical Properties

Applied Sciences ◽

10.3390/app10196911 ◽

2020 ◽

Vol 10 (19) ◽

pp. 6911

Author(s):

Malavika Nair ◽

Serena M. Best ◽

Ruth E. Cameron

Keyword(s):

Tissue Engineering ◽

Cell Viability ◽

Biomedical Applications ◽

Engineering Application ◽

Chemical Properties ◽

Tissue Engineering Application ◽

Physical And Chemical Properties ◽

Crosslinking Process ◽

Physical And Chemical ◽

And Chemical Properties

Collagen-based constructs have emerged in recent years as ideal candidates for tissue engineering implants. For many biomedical applications, collagen is crosslinked in order to improve the strength, stiffness and stability of the construct. However, the crosslinking process may also result in unintended changes to cell viability, adhesion or proliferation on the treated structures. This review provides a brief overview of some of both the most commonly used and novel crosslinkers used with collagen, and suggests a framework by which crosslinking methods can be compared and selected for a given tissue engineering application.

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