scholarly journals Clinical Applications of Neuropsychoanalysis: Hypotheses Toward an Integrative Model

2021 ◽  
Vol 12 ◽  
Author(s):  
Daniela Flores Mosri
Keyword(s):  
Clinical Applications ◽  
Integrative Model ◽  
Human Suffering ◽  
Affective Neuroscience ◽  
The Unconscious ◽  
Psychoanalytic Technique ◽  
Neurological Patients ◽  
Gradual Development ◽  
The Mind

Neuropsychoanalysis has been established as a field based on the dialog between psychoanalysis and the neurosciences. Freud was a neurologist for 20 years and used the neuroscientific knowledge of his time as the foundation of his metapsychology. Psychoanalysis has predominantly relied on its own method to develop techniques for the different psychoanalytic treatments. It rarely uses contributions from fields outside psychoanalysis that could enrich its understanding of the mind. Neuropsychoanalysis has informed and revised several topics in psychoanalysis, for example consciousness and the unconscious, dreams, and affect amongst many others. Clear clinical applications of neuropsychoanalysis can be appreciated in the work with neurological patients. However, a constant question from clinicians is whether neuropsychoanalytic findings can contribute to psychoanalytic treatments with non-neurological patients. This paper explores clinical applications of neuropsychoanalysis mainly based on affective neuroscience to propose an analysis of emotions that may contribute to the gradual development of a neuropsychoanalytically informed psychotherapy. The task of integrating neuroscientific knowledge into psychoanalytic technique is still considered a challenge of accentuated complexity, but it is at the same time a necessary and promising endeavor that aims at improving the quality of the treatments available for human suffering and psychopathology.

The Cognitive-Affective Neuroscience of the Unconscious

CNS Spectrums ◽  
2006 ◽  
Vol 11 (8) ◽  
pp. 580-583 ◽  
Author(s):  
Dan J. Stein ◽  
Mark Solms ◽  
Jack van Honk
Keyword(s):  
Recent Work ◽  
Computational Models ◽  
Laboratory Data ◽  
Clinical Material ◽  
Clinical Implications ◽  
Affective Neuroscience ◽  
Ongoing Debate ◽  
The Unconscious ◽  
Unconscious Cognition ◽  
The Mind

ABSTRACTThere is an ongoing debate about how best to conceptualize the unconscious. Early psychodynamic views employed theories influenced by physics to explain clinical material, while subsequent cognitivist views relied on computational models of the mind to explain laboratory data. More recently, advances in cognitive-affective neuroscience have provided new insights into the workings of unconscious cognition and affect. We briefly review some of this recent work and its clinical implications.

Reflecting the Sky in Water

2017 ◽  
Vol 3 (1) ◽  
pp. 112-126 ◽  
Author(s):  
Ilaria Cristofaro
Keyword(s):  
The Unconscious ◽  
Related Case ◽  
Quality Of Water ◽  
Fluid Properties ◽  
Phenomenological Perspective ◽  
Auto Ethnography ◽  
The Individual ◽  
Artificial Water ◽  
Land Water

From a phenomenological perspective, the reflective quality of water has a visually dramatic impact, especially when combined with the light of celestial phenomena. However, the possible presence of water as a means for reflecting the sky is often undervalued when interpreting archaeoastronomical sites. From artificial water spaces, such as ditches, huacas and wells to natural ones such as rivers, lakes and puddles, water spaces add a layer of interacting reflections to landscapes. In the cosmological understanding of skyscapes and waterscapes, a cross-cultural metaphorical association between water spaces and the underworld is often revealed. In this research, water-skyscapes are explored through the practice of auto-ethnography and reflexive phenomenology. The mirroring of the sky in water opens up themes such as the continuity, delimitation and manipulation of sky phenomena on land: water spaces act as a continuation of the sky on earth; depending on water spaces’ spatial extension, selected celestial phenomena can be periodically reflected within architectures, so as to make the heavenly dimension easily accessible and a possible object of manipulation. Water-skyscapes appear as specular worlds, where water spaces are assumed to be doorways to the inner reality of the unconscious. The fluid properties of water have the visual effect of dissipating borders, of merging shapes, and, therefore, of dissolving identities; in the inner landscape, this process may represent symbolic death experiences and rituals of initiation, where the annihilation of the individual allows the creative process of a new life cycle. These contextually generalisable results aim to inspire new perspectives on sky-and-water related case studies and give value to the practice of reflexive phenomenology as crucial method of research.

scholarly journals High Integrity and Fidelity of Long-Term Cryopreserved Umbilical Cord Blood for Transplantation

2021 ◽  
Vol 10 (2) ◽  
pp. 293
Author(s):  
Gee-Hye Kim ◽  
Jihye Kwak ◽  
Sung Hee Kim ◽  
Hee Jung Kim ◽  
Hye Kyung Hong ◽  
...  
Keyword(s):  
Stem Cell ◽  
Cord Blood ◽  
Umbilical Cord ◽  
Umbilical Cord Blood ◽  
Clinical Applications ◽  
Hematopoietic Stem ◽  
Cd34 Cells ◽  
Hsc Transplantation

Umbilical cord blood (UCB) is used as a source of donor cells for hematopoietic stem cell (HSC) transplantation. The success of transplantation is dependent on the quality of cord blood (CB) units for maximizing the chance of engraftment. Improved outcomes following transplantation are associated with certain factors of cryopreserved CB units: total volume and total nucleated cell (TNC) count, mononuclear cell (MNC) count, and CD34+ cell count. The role of the storage period of CB units in determining the viability and counts of cells is less clear and is related to the quality of cryopreserved CB units. Herein, we demonstrate the recovery of viable TNCs and CD34+ cells, as well as the MNC viability in 20-year-old cryopreserved CB units in a CB bank (MEDIPOST Co., Ltd., Seongnam-si, Gyeonggi-do, Korea). In addition, cell populations in CB units were evaluated for future clinical applications. The stable recovery rate of the viability of cryopreserved CB that had been stored for up to 20 years suggested the possibility of uses of the long-term cryopreservation of CB units. Similar relationships were observed in the recovery of TNCs and CD34+ cells in units of cryopreserved and fresh CB. The high-viability recovery of long-term cryopreserved CB suggests that successful hematopoietic stem cell (HSC) transplantation and other clinical applications, which are suitable for treating incurable diseases, may be performed regardless of long-term storage.

scholarly journals Coenzyme Q10: Clinical Applications beyond Cardiovascular Diseases

Nutrients ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 1697
Author(s):  
Lara Testai ◽  
Alma Martelli ◽  
Lorenzo Flori ◽  
Alessandro Colletti ◽  
Arrigo F. G. Cicero
Keyword(s):  
Cardiovascular Diseases ◽  
Coenzyme Q10 ◽  
Inverse Correlation ◽  
Chronic Fatigue ◽  
Clinical Applications ◽  
Blood Levels ◽  
Muscle Disorders ◽  
Fatigue Syndrome ◽  
Antioxidant Agent

Coenzyme Q10 (CoQ10) is an essential cofactor in oxidative phosphorylation (OXPHOS), present in mitochondria and cell membranes in reduced and oxidized forms. Acting as an energy transfer molecule, it occurs in particularly high levels in the liver, heart, and kidneys. CoQ10 is also an anti-inflammatory and antioxidant agent able to prevent the damage induced by free radicals and the activation of inflammatory signaling pathways. In this context, several studies have shown the possible inverse correlation between the blood levels of CoQ10 and some disease conditions. Interestingly, beyond cardiovascular diseases, CoQ10 is involved also in neuronal and muscular degenerative diseases, in migraine and in cancer; therefore, the supplementation with CoQ10 could represent a viable option to prevent these and in some cases might be used as an adjuvant to conventional treatments. This review is aimed to summarize the clinical applications regarding the use of CoQ10 in migraine, neurodegenerative diseases (including Parkinson and Alzheimer diseases), cancer, or degenerative muscle disorders (such as multiple sclerosis and chronic fatigue syndrome), analyzing its effect on patients’ health and quality of life.

COMMITTEE ON NUTRITION

PEDIATRICS ◽  
1956 ◽  
Vol 18 (3) ◽  
pp. 509-510
Author(s):  
Keyword(s):  
Code Of Ethics ◽  
Medical Profession ◽  
Consumer Good ◽  
Childhood And Adolescence ◽  
Promotional Material ◽  
Executive Board ◽  
American Academy Of Pediatrics ◽  
The Status ◽  
The Mind

THE Committee on Nutrition has been designated by the Executive Board of the American Academy of Pediatrics to serve in a consultative capacity in determining the suitability of advertisements of nutritional products in the official publications of the Academy. Understanding between industry and the medical profession will be fostered by a readily available statement of the basis upon which judgment of advertisements of nutritional products will be made. Assurance can be given that this will be applied objectively, fairly and with sympathetic understanding of the position of industry. It is hoped that thereby this statement can assume the status of a Code of Ethics and Etiquette in the promotion of products intended for maintenance of optimal nutrition or treatment of disorders of nutrition in infancy, childhood and adolescence. The Committee on Nutrition will remain receptive to counsel from all sources, and sensitive to the implications of its own statements and actions. The following principles will be continuously re-examined in the light of experience and pertinent evidence. Good Advertising Good advertising serves the interest of both merchant and consumer. Good advertising begins with a reliable product. Good advertising achieves a pleasant informative memory of the product and its usefulness in the mind of the consumer. In short, this implies an honest product, truthfully and artistically advertised. Honesty is the best cornerstone upon which to build the type of promotion that will serve the mutual interest of industry, the consumer, and the medical profession. Quality of the Product Proof of quality of the product must at all times be available to those who must evaluate promotional material. This applies to foods and to individual ingredients such as vitamins, minerals, amino acids, fatty acids, etc.

Salivary peptide histatin 1 mediated cell adhesion: a possible role in mesenchymal-epithelial transition and in pathologies

2018 ◽  
Vol 399 (12) ◽  
pp. 1409-1419 ◽  
Author(s):  
Irene A. van Dijk ◽  
Enno C.I. Veerman ◽  
Eric A.J. Reits ◽  
Jan G.M. Bolscher ◽  
Jan Stap
Keyword(s):  
Cell Adhesion ◽  
Oral Cavity ◽  
Potential Function ◽  
Clinical Applications ◽  
Epithelial Barrier ◽  
Salivary Peptide ◽  
Mesenchymal To Epithelial Transition ◽  
Mesenchymal Epithelial Transition

Abstract Histatins are histidine-rich peptides present in the saliva of humans and higher primates and have been implicated in the protection of the oral cavity. Histatin 1 is one of the most abundant histatins and recent reports show that it has a stimulating effect on cellular adherence, thereby suggesting a role in maintaining the quality of the epithelial barrier and stimulating mesenchymal-to-epithelial transition. Here we summarize these findings and discuss them in the context of previous reports. The recent findings also provide new insights in the physiological functions of histatin 1, which are discussed here. Furthermore, we put forward a possible role of histatin 1 in various pathologies and its potential function in clinical applications.

The Evolution of the Colour Sense

1901 ◽  
Vol 47 (199) ◽  
pp. 678-679
Author(s):  
F. W. Edridge-Green
Keyword(s):  
Nerve Impulse ◽  
The Other ◽  
Physiological Basis ◽  
Black And White ◽  
Normal Distance ◽  
Colour Sense ◽  
Two Factors ◽  
Colour Blindness ◽  
The Mind

All the facts which can be gathered from the study of museums or literature point to the conclusion that the sense of light was developed first, then the sense of colour. The tendency has been to regard colour-blindness as “chromic myopia;” but this is not correct unless there is a defective perception of light as well, as shown by the cases which I have recorded. A man may be able to see light of all colours at twice the normal distance, and yet be colour-blind. I specially wish to emphasise the fact that there is no definite relation between light and colour. When light falls upon the eye it sets up a nerve impulse, which is conveyed to the brain. In the impulse itself we have the physiological basis of light, and in the quality of the impulse the physiological basis of colour. My contention is that these two factors are perceived by two entirely different sets of cerebral cells, those devoted to the perception of colour being developed at a later period than those conveying to the mind the sensation of light. All the evidence which can be obtained shows that all objects were first seen as in a photograph, that is, in different degrees of black and white. In the evolution of the colour sense those waves which differ most physically, namely, red and violet, were first recognised as different, the remainder of the spectrum appearing grey. Homer's colour vision was of this class, which represents the degree just preceding total colour-blindness. I have recorded a case of this kind of a man who was colour-blind with one eye, and who was therefore able to tell me exactly how objects appeared with this eye. He said that the spectrum appeared nearly all grey, but with a tinge of red at one end and a tinge of violet at the other; he could see very much better with the colour-blind eye than with the other.

scholarly journals Recent Developments in Clinical Applications of Mesenchymal Stem Cells in the Treatment of Rheumatoid Arthritis and Osteoarthritis

2021 ◽  
Vol 12 ◽  
Author(s):  
Joel Jihwan Hwang ◽  
Yeri Alice Rim ◽  
Yoojun Nam ◽  
Ji Hyeon Ju
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Trials ◽  
Clinical Applications ◽  
Clinical Settings ◽  
Positive Outcomes ◽  
Joint Function ◽  
Safety And Efficacy ◽  
High Expectations ◽  
Recent Developments

Mesenchymal stem cell (MSC) therapies have been used as cell-based treatments for decades, owing to their anti-inflammatory, immunomodulatory, and regenerative properties. With high expectations, many ongoing clinical trials are investigating the safety and efficacy of MSC therapies to treat arthritic diseases. Studies on osteoarthritis (OA) have shown positive clinical outcomes, with improved joint function, pain level, and quality of life. In addition, few clinical MSC trials conducted on rheumatoid arthritis (RA) patients have also displayed some optimistic outlook. The largely positive outcomes in clinical trials without severe side effects establish MSCs as promising tools for arthritis treatment. However, further research is required to investigate its applicability in clinical settings. This review discusses the most recent advances in clinical studies on MSC therapies for OA and RA.

Sign in / Sign up

Export Citation Format

Share Document