scholarly journals Randomised Control Trial Comparing Cypermethrin-Based Preparations in the Prevention of Infectious Bovine Keratoconjunctivitis in Cattle

Animals ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 184
Author(s):  
Jennifer Allan ◽  
Steven Van Winden

Infectious bovine keratoconjunctivitis (IBK) caused by Moraxella bovis is commonly seen in the summer months spread by face flies. This trial investigated the difference in incidence of IBK cases from natural exposure between two groups of animals, one treated with Cypermethrin pour-on preparation (PON, n = 98) and one with Cypermethrin impregnated ear tags (TAG, n = 99). Daily Live Weight Gain (DLWG) difference was investigated between animals with cases and those without and between treatment groups. A randomised positive control study, enrolled 197 animals split into two treatment groups. Cases of IBK and DLWG were recorded over the grazing season (April–November 2018). Fifty-four cases of IBK were recorded. There was no association between the two treatment groups (p = 0.362) and case status. Breed and under 12 months old were significant factors for having a case; (OR 2.3, p = 0.014 and OR 3.5, p < 0.001 respectively). There was no difference in DLWG between animals that had a case and animals that had not (p = 0.739) or between the two treatment groups (p = 0.215). Based on our results, there is no significant difference between PON or TAG preparations in the prevention of IBK. Younger animals and white-faced breeds are significantly more likely to suffer with IBK.

2022 ◽  
Vol 78 (01) ◽  
pp. 6608-2022
Author(s):  
SYAFRUDDIN SYAFRUDDIN ◽  
SRI WAHYUNI ◽  
GHOLIB GHOLIB ◽  
TONGKU NIZWAN SIREGAR

This study was conducted to compare several methods for inducing pseudopregnancy in local rabbits. The study used 25 clinically healthy rabbits of local breeds, aged 1-1.5 years, with a bodyweight of 1.8-2.2 kg. The rabbits were divided into five treatment groups (n = 5): R1, R2, R3, R4, and R5. Each group was given a different treatment. Group R1 was injected intramuscularly with 100 IU PMSG and mated with males three days later, which was followed by an intravenous injection of 75 IU hCG. Pseudopregnancy in group R2 was induced through artificial copulation by inserting a 1 cm long cotton bud into vaginal lumen at 5 a.m. Pseudopregnancy in group R3 was induced using 50 IU hCG intramuscularly. Group R4 was injected intravenously with 5 g GnRH and then intramuscularly with 100 IU PMSG and three days later with 75 IU hCG. Blood samples were collected on days 2, 4, 6, and 8 for estrogen and progesterone measurement, whereas an ovarian histological observation of all groups was performed on day 8. The results show that the highest concentration of estrogen was obtained in group R2, which was significantly different from the other groups (P <0.05), but the difference in examination time was not statistically significant (P > 0.05). Furthermore, the concentration of progesterone in all groups fluctuated at various times of the day. Progesterone concentrations were higher in group R5, in which pseudopregnancy was induced with PMSG and hCG. Group R5 showed a significant difference (P <0.05) with R2, R3, and R4, but the difference with the positive control group (R1) was not significant (P > 0.05). The numbers of corpora lutea in groups R1, R2, R3, R4, and R5 were, respectively, 6.87 ± 1.58, 6.22 ± 2.71, 6.74 ± 1.94, 5.98 ± 2.04, and 8.8 ± 1.90, and the largest diameter was obtained in R5 (1.65 ± 0.37 mm). In conclusion, the best method of inducing pseudopregnancy in local rabbits is the administration of PMSG and hCG.


2017 ◽  
Vol 2 (2) ◽  
pp. 147
Author(s):  
Triswanto Sentat ◽  
Susiyanto Pangestu

Kersen leaf (Muntingia calabura L.) contains tannins, flavonoids and polyphenol compounds allegedly have analgesic effect. The objective was to determine the analgesic effect of ethanol extract of kersen leaves and to determine the most effective analgesic dose. This study was an experimental research. Leaves were extracted with ethanol 70% and the analgesic effect test was divided into 5 groups: negative control treatment (distilled water), positive control (mefenamic acid 2.6mg/kg), kersen leaf ethanol extract first dose (100mg/kg), second dose (200mg/kg) and tthird dose (400mg/kg). Giving treatments by oral, after 30 minutes, the mices were given a pain inductor with 0.5% acetic acid by intra peritonial administration. Analgesic power was calculated by counting the number of writhing in mice for 1 hour. The results showed that the ethanol extract of cherry leaf has analgesic effect. From the calculation of the first dose analgesic power (42.9%), second dose (59.4%) and the third dose 69.9%. Statistical test results kruskal wallis value of p=0.011 (p<0.05) showed a significant difference between all analgesic treatment groups. The conclusion of this study is all of the ethanol extract had analgesic effects on male white mice, whereas a dose of 400mg/kg is the most effective analgesic dose.


2018 ◽  
Vol 47 ◽  
pp. 07006
Author(s):  
Saryono Saryono ◽  
Hesti Devinta ◽  
Abdul Haris Budi Widodo ◽  
Arif Imam Hidayat

Contaminated water often affects the occurrence of periodontitis in the coastal area. The diabetic hypercholesterolemia-induced periodontitis in Indonesia is very high. The use of coenzyme Q10 to treat this disease has never been investigated yet. Therefore, this study aimedto analyze the effect of coenzyme Q10 on the lipid profile of diabetic hypercholesterolemia-induced periodontitis.Twenty four rats were randomized into 6 groups (G1-G6). The groups (G1-G3) are healthy, negative and positive control group respectively. The treatment groups (G4-G6) are diabetic hypercholesterolemia-induced rats given coenzyme q10 dose of 13,5; 27 and 54 mg/kg respectively. Rats were induced by periodontitis, hypercholesterolemia and diabetes mellitus. Coenzyme Q10 was administered orally using 2 mL gastric tube once a day for 14 days. Lipid profile including triglycerides, HDL, and atherogenic index (IA) was measured enzymatically by the CHOD-PAP method. Data were analyzed by one-way ANOVA test and followed by the Least Significant Difference (LSD) post hoc test.Coenzyme Q10 with a dose of 54 mg/kgis effective in lowering triglyceride, and atherogenic index and increasing HDL level in diabetic hyperlipidemia-induced periodontitis rats model. This research supports the potential effects of coenzyme Q10 supplementation to improve lipid profile in diabetic hypercholesterolemia-induced periodontitis in the coastal area.


2018 ◽  
Vol 1 (2) ◽  
pp. 1-17
Author(s):  
Fahcreza ◽  
Elsa Iskandar ◽  
Rachmat Hidayat ◽  
Petty Purwanita ◽  
Anang Tribowo ◽  
...  

Abstract Background: Chemical trauma to the cornea is an emergency condition of the eye that requires early diagnosis and good treatment. Alkaline have ability to saponify fatty acids in cells and cell membranes which can make penetration into the stroma and destroy proteoglycans and collagen in cells. Aloe vera (AV) contains several active substances that are reported to have anti-inflammatory, immunomodulatory, and wound healing effects. AV has been reported to accelerate the healing process of corneal epithelial defects by increasing fibroblast proliferation, collagen production and growth factor production. This study aims to determine the difference between the effect of aloe vera extract with a concentration of 10%, 20%, 40% and BSS on the healing of extensive corneal lesions in white wistar rats alkaline trauma models. Method: This study was an experimental study with a pre and posttest only with control group design in vivo approach to 30 Wistar white rats which were divided into 5 treatment groups for 3 days. Comparative analysis of effectiveness using the ANNOVA test or the Kruskal Wallis test and continued by the post hoc test. Results: Based on the one way ANOVA test there was a statistically significant difference in effectiveness between the five treatment groups on the percentage of corneal wound healing area and TGF-β expression with an assessment of p = 0,000 each. The administration of alloevera (AV) concentration of 20% had a significant difference in percentage of healing of corneal lesions and TGF-β expression compared with other treatment groups with p = 0,000 each. Large differences in the area of corneal lesions in the 40% AV group were -0.45 in the BBS group, 0.146 in the 10% AV group, 0.493 in the 20% AV group. The difference in the AV group 10% was 0.30 in the BBS group, -064 in the AV group 20%, and -0.14 in the AV group 40%. However, TGFβ expression in the normal control group that did not receive treatment was 54.94 (53.21-56-12). TGFβ levels in the BSS group were 10.44, the 10% aloe vera group was 25.43, 47.99 for the 20% aloe vera group and 37.95 for the 40% aloe vera group. Conclusion: There is a difference between the effect of aloe vera extract with concentrations of 10%, 20%, 40% and BSS on the extensive healing of corneal lesions in white wistar rats with alkaline chemical trauma models.


2018 ◽  
Vol 33 (01) ◽  
pp. 067-072 ◽  
Author(s):  
Fırat Seyfettinoğlu ◽  
Özkan Köse ◽  
Hasan Ulaş Oğur ◽  
Ümit Tuhanioğlu ◽  
Hakan Çiçek ◽  
...  

AbstractThis study was aimed to investigate the role of anatomic variations in patellofemoral alignment in patients with or without Osgood-Schlatter disease (OSD) and to determine the potential anatomic risk factors that may play role in the etiology. This prospective observational case-control study was conducted on two groups of adolescent patients. Group 1 comprised patients who were diagnosed as having OSD and group 2 consisted of an equal number of age-matched patients who presented to the outpatient clinic with traumatic knee injury and underwent knee radiographic examination but without a diagnosis of OSD. Age, height, weight, body mass index (BMI), dominant side, and level of sporting activity were recorded. Quadriceps (Q) angles were measured using a long-arm goniometer with patients lying in the supine position with their knees in full extension and contracting the Q muscles. On anteroposterior, lateral knee, and tangential patella (Merchant and Laurin views) radiographs, the following measurements were performed: Insall–Salvati (IS), Caton–Deschamps (CD), and Blackburne–Peel (BP) indexes, congruence angles, lateral patellofemoral angles, sulcus angles, and patella type according to Grelsamer's morphology classification. Both groups were similar in respect of age (p = 0.160), sex (p = 0.311), height (p = 0.326), weight (p = 0.596), BMI (p = 0.153), and dominancy (p = 0.500). The rate of patients engaged in sports activities was significantly greater in the OSD group (p = 0.003). No significant difference was determined between the groups in respect to IS index, CD index, BP index, sulcus angle, lateral patellofemoral angle, and congruence angle (p–values: 0.358, 0.995, 0.912, 0.802, 1.000, and 0.907, respectively). The mean Q angle was measured as 15.6 ± 2.2 degrees in the OSD group and 14.3 ± 2.5 degrees in the control group (p = 0.014). Despite the difference being statistically significant, it was clinically insignificant because the difference was only 1.3 degrees. The principle etiologic factor seems to be increased physical activity rather than subtle variations is patellofemoral anatomy and alignment of extensor mechanism.


1975 ◽  
Vol 20 (1) ◽  
pp. 123-131 ◽  
Author(s):  
P. H. Brooks ◽  
D. J. A. Cole ◽  
W. J. N. Jennings

SUMMARYThe carcass characteristics of young adult female pigs (gilts) slaughtered after weaning their first litters have been investigated using three groups of 19 Landrace × (Landrace×Large White) gilts. In two treatment groups gilts were mated at their pubertal oestrus and suckled their piglets for 5 to 11 and 35 to 42 days respectively. These gilts were slaughtered on average 10 days after weaning. A third control group consisted of unmated gilts slaughtered at 118 kg live weight.There was no significant difference in the killing-out percentage for the three groups. The carcasses of the gilts which farrowed contained significantly less fat (P<0·001) than those of the unmated controls. The carcasses of the farrowed gilts had significantly lighter middle sections (P<0·001) and significantly heavier shoulders (P<0·001) than the controls.Despite the variations in tissue yield and distribution, the yield of prime joints for the gilts which had farrowed was only 0·62 percentage units less than that of the controls.No commercially significant variations between groups in meat quality were observed.


1960 ◽  
Vol 2 (01) ◽  
pp. 45-57 ◽  
Author(s):  
J. A. Crichton ◽  
J. N. Aitken ◽  
A. W. Boyne

1. The four systems of rearing dairy heifer calves, described in Part 1 of this series are now studied for their effect on absolute and relative growth rates to maturity.2. Data on live-weights and measurements and the percentages of mature size attained by these at 44, 80, 104, 132, 182, 260 and 312 weeks of age are tabulated.3. In all groups the measurement to reach maturity earliest was circumference of metacarpus followed in order by length of back, height at withers and width of hooks.4. By 6 years of age all groups had attained approximately the same body size. Maturity in the LL group in terms of four skeletal measurements was delayed by only 9 months, and in the case of HL and LH animals by 5 and 4 months respectively.5. All groups showed the same general pattern of relative growth but the effect of restricted feeding was to increase at the younger ages the difference i n percentage of mature size between early and late maturing measurements. After 44 weeks of age the rate of growth was most rapid in those measurements which were furthest from maturity then.6. The rate of tissue deposition was markedly increased in high plane animals during early pregnancy compared with low plane. Evidence is presented to show that much of this was lost during lactation.7. At first oestrus, animals in all four treatment groups had reached the same percentage of mature size for each body dimension (except for length of back in the LL group).8. From data on 5 animals it is shown that although growth in height at withers and length of back ceased by 6 years of age there was slow but continuous growth in live-weight, middle and heart girths and width of hooks to 9 years of age.


1966 ◽  
Vol 8 (1) ◽  
pp. 29-38 ◽  
Author(s):  
G. A. Lodge ◽  
F. W. H. Elsley ◽  
R. M. MacPherson

1. Twelve sets of 3 litter-sister Large White gilts were mated at first oestrus after reaching 250 lb. live-weight and given daily during 3 successive pregnancies either 6 lb. (A), 3 lb. (B) or 3 lb. for 76 days then 6 lb. until parturition (C) of the same meal mixture. During an 8-week lactation all were given 4 lb. meal plus 0·8 lb. per piglet suckled.2. There was a significant linear increase in numbers born with successive parities (P<0·05) but no significant differences between treatment or sister groups. There was a highly significant difference between treatment groups in mean piglet birth weight (P< 0·001) but no parity effect; mean birth weights were 2·76, 2·40 and 2·58 Ib. for Groups A, B and C respectively. Differences between sister groups in mean piglet birth weight were also significant (P<0·05).3. Post-natal litter performance was poor for all groups, probably because of the presence of E. coli, but there was no evidence of treatment effects other than on 3-week weight of third litters, which was significantly greater in Group C than in A or B (P<0·05). There were no significant effects on either number or weight of piglets at 8 weeks.


Author(s):  
C. Sudharsan ◽  
S. Senthil Murugan ◽  
Biju Chacko ◽  
Sanis Juliet ◽  
Suresh N. Nair ◽  
...  

Background: Fat and oil are commonly used in poultry diets to increase energy density and also to increase the palatability of feed, feed efficiency and for deposition of fat in broilers. Thus a study was proposed to find the effects of dietary replacement of saturated fatty acid rich palm oil (PO) by omega-3 rich rapeseed oil (RO) on growth performance and economics in broilers. Method: The growth performance feeding trial was conducted in 160 day-old broilers (vencobb 400) with four treatment groups (G1, G2, G3 and G4) with four replicates of ten chicks each. The basal diet (R1) was prepared with palm oil included at the rate of 1.5, 3, and 4.5 per cent in pre-starter, starter and finisher ration, respectively and fed to G1. The other treatment groups G2, G3 and G4 received R2, R3 and R4 experimental rations respectively. The experimental rations R2, R3 and R4 were prepared with rapeseed oil replacing 25, 50 and 100 per cent of palm oil which was included in R1. Result: The broiler ration prepared with rapeseed oil at 50 and 100 per cent level (G3 and G4) replacing palm oil showed increased body weight gain (P less than 0.01) and better feed conversion ratio (P less than 0.05) than G1 group. There was no significant difference in the feed intake among the different treatment groups. Profit per kg live weight in G3 (Rs.12.06) and G4 (Rs.11.14) was more than G1 (Rs.8.21) and G2 (Rs.6.57). The supplementation of omega-3 rich rapeseed oil had significantly improved the performance of broilers.


1961 ◽  
Vol 3 (1) ◽  
pp. 19-28 ◽  
Author(s):  
G. A. Lodge ◽  
R. M. McPherson

1. Nine groups of 4 litter-mate Wessex Saddleback gilts were divided on a within-litter basis between 4 treatments so that they were reared from 8 weeks of age to 200 1b. live-weight according to different levels of total feed intake; (a) a high level rising to 8·0 1b. meal per day at 200 1b. live-weight, (b) a medium level approximately 80% of the high, (c) a low level approximately 60% of the high and (d) changing from the low to the medium level between 14 and 16 weeks of age. From 200 1b. live-weight to mating at first heat after reaching 300 1b. all were fed to the medium scale (6·5 1b. meal per day), and all were treated alike during each of 3 pregnancies and lactations.2. Mean rate of growth from weaning to 100 1b. and from 100 to 200 1b. differed significantly between treatments (P<0·001), and mean efficiency of feed conversion of the low-plane group was significantly poorer than that of the high-plane group (P<0·05) from weaning to 100 1b. live-weight.3. All gilts, regardless of treatment, reached puberty at approximately the same age (25 weeks), with the result that mean weight at puberty differed markedly between treatments (P<0·001); 116, 154, 189 and 147 1b. for treatments (a) to (d) respectively.4. Gilts reared on medium and high planes of feeding exhibited oestrus less strongly than those reared on the low-plane, with the result that mean weight at successful mating was significantly greater in these two groups (P<0·05).5. Four gilts in the low-plane group and one in the high-plane group failed to conceive after repeated matings, but numbers were insufficient to indicate the significance of this.6. From the original 36 gilts, 27 first litters, 26 second litters and 25 third litters were produced and reared to 8 weeks of age. There was no significant difference between treatment groups in litter size at birth, mean weight of piglets at 3 or 8 weeks of age or total litter weight at weaning.7. Trouble from temporary collapse of the legs was experienced in all but one gilt of the high-plane group between 6½ and 7½ months of age.


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