scholarly journals DNA Nanodevice-Based Drug Delivery Systems

Biomolecules ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 1855
Author(s):  
Chaoyang Guan ◽  
Xiaoli Zhu ◽  
Chang Feng
Keyword(s):  
Biomedical Applications ◽  
Chemical Properties ◽  
Tumor Treatment ◽  
Controllable Release ◽  
Dna Materials ◽  
Version 2.0 ◽  
Good Biocompatibility ◽  
Chemical Stimuli ◽  
Physical And Chemical ◽  
And Chemical Properties

DNA, a natural biological material, has become an ideal choice for biomedical applications, mainly owing to its good biocompatibility, ease of synthesis, modifiability, and especially programmability. In recent years, with the deepening of the understanding of the physical and chemical properties of DNA and the continuous advancement of DNA synthesis and modification technology, the biomedical applications based on DNA materials have been upgraded to version 2.0: through elaborate design and fabrication of smart-responsive DNA nanodevices, they can respond to external or internal physical or chemical stimuli so as to smartly perform certain specific functions. For tumor treatment, this advancement provides a new way to solve the problems of precise targeting, controllable release, and controllable elimination of drugs to a certain extent. Here, we review the progress of related fields over the past decade, and provide prospects for possible future development directions.

Carbon Dots: Synthesis, Properties and Biomedical Applications

2021 ◽  
Author(s):  
Guili Ge ◽  
Lin Li ◽  
Dan Wang ◽  
Mingjian Chen ◽  
Zhaoyang Zeng ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Biomedical Applications ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Synthesis Properties ◽  
New Type ◽  
Low Toxicity ◽  
Good Biocompatibility ◽  
Physical And Chemical ◽  
And Chemical Properties

Carbon dots (CDs) are a new type of carbon nanomaterial that have unique physical and chemical properties, good biocompatibility, low toxicity, easy surface functionalization, making them widely used in biological...

scholarly journals Biocompatible Material from Indonesian Natural Resource of Wild Silkmoth Cocoon

2018 ◽  
Vol 1 (2) ◽  
pp. 47
Author(s):  
Tjokorda Gde Tirta Nindhia ◽  
Zdenek Knejzlík ◽  
Tomáš Ruml ◽  
I Wayan Surata ◽  
Tjokorda Sari Nindhia
Keyword(s):  
Mechanical Properties ◽  
Natural Resource ◽  
Chemical Properties ◽  
Hot Water ◽  
Physical And Chemical Properties ◽  
Living Things ◽  
Biocompatibility Testing ◽  
Good Biocompatibility ◽  
Physical And Chemical ◽  
And Chemical Properties

Silk can be produced by spider or insect and have prospect as biomaterial for regenerative healing in medical treatment. Silk having physical and chemical properties that support biocompatibility in the living things..In this research, silk that was obtained from Indonesia natural resource of Attacus atlas silkmoth was explored and then will be  developed for biocompatible biomaterial. The treatment with NaOH was developed to separate the fiber from the cocoon. The obtained fiber is investigated its mechanical property by performing tensile test for single fiber. The biocompatibility testing was conducted with human cell (osteosarccoma) cultivation. The result identify that separation by using NaOH yield better better mechanical properties comparing konvenstional method with boiling in hot water. Biocompatibility testing indicate that the the fiber having good biocompatibility.

Sensing Uric Acid with Bimetallic Nano Ag-Pt Particles

2013 ◽  
Vol 543 ◽  
pp. 72-75
Author(s):  
Balakrishnan Karthikeyan ◽  
Marimuthu Murugavelu
Keyword(s):  
Uric Acid ◽  
High Surface ◽  
Chemical Properties ◽  
Major Product ◽  
Physical And Chemical Properties ◽  
Sensing Applications ◽  
Wide Range ◽  
Good Biocompatibility ◽  
Physical And Chemical ◽  
And Chemical Properties

The emergence of nanoparticles (NPs) has opened new opportunities in analytical chemistry [. These NPs exhibit different properties and functionalities when compared to monometallic particles. In particular, they show enhanced selectivity and reactivity when used as catalysts and sensors [2-. The NPs have large surface area, high surface free energy, good biocompatibility and suitability, and it has been used in constructing electrochemical biosensors [7, . The fascinating physical and chemical properties of NPs offer excellent prospects for a wide range of bio sensing applications [ . Uric acid (UA) is the principal final product of purine metabolism in the human body [1. It has been shown that extreme abnormalities of UA levels are symptoms of several diseases (e.g. gout, hyper uricaemia and LeschNyhan syndrome)[11,1.In general, electro active UA can be irreversibly oxidized in aqueous solution and the major product is allantoin [1. In continuation of our interest with the bimetal nanoparticle (BNP) sensing here in this study, we employed Ag/Pt BNPs for detecting of UA.

scholarly journals 2D Materials for Environment, Energy, and Biomedical Applications

2021 ◽  
Vol 2 (10) ◽  
pp. 977-984
Author(s):  
Divya Chauhan ◽  
Mohammad Ashfaq ◽  
Neetu Talreja ◽  
Ramalinga Viswanathan Managalraja
Keyword(s):  
Electronic Structure ◽  
Biomedical Applications ◽  
Short Communication ◽  
Biomedical Application ◽  
2D Materials ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Energy Environment ◽  
Physical And Chemical ◽  
And Chemical Properties

Recently 2D materials are booming in the field of energy, environment, and biomedical application. Incorporation of metal/non-metal within 2D materials significantly influences the physical and chemical properties, making them intriguing materials for various applications. The advancement of 2D material requires strategic modification by manipulating the electronic structure, which remains a challenge. Herein, we describe 2D materials for the environment, energy, and biomedical application. A predominant aim of this short communication is to summarize the literature on the advanced environment, energy, and biomedical application (especially COVID-19).

BIOMEDICAL APPLICATIONS OF ELECTROSPUN NANOFIBERS

2020 ◽  
Vol 27 (11) ◽  
pp. 2030001
Author(s):  
ZHANG YANCONG ◽  
DOU LINBO ◽  
MA NING ◽  
WU FUHUA ◽  
NIU JINCHENG
Keyword(s):  
Biomedical Applications ◽  
Three Dimensional ◽  
Chemical Properties ◽  
Electrospun Nanofibers ◽  
High Porosity ◽  
Nanofiber Diameter ◽  
Surface Microscopy ◽  
Different Shapes ◽  
Physical And Chemical ◽  
And Chemical Properties

Electrospun technology is a simple and flexible method for preparation of nanofiber materials with unique physical and chemical properties. The nanofiber diameter is adjustable from several nanometers to few microns during the preparation. Electrospun nanofiber materials are easy to be assembled into different shapes of three-dimensional structures. These materials exhibit high porosity and surface area and can simulate the network structures of collagen fibers in a natural extracellular matrix, thereby providing a growth microenvironment for tissue cells. Electrospun nanofibers therefore have extensive application prospects in the biomedicine field, including in aerospace, filtration, biomedical applications, and biotechnology. Nanotechnology has the potential to revolutionize many fields, such as surface microscopy, silicon fabrication, biochemistry, molecular biology, physical chemistry, and computational engineering, while the advent of nanofibers has increased the understanding of nanotechnology among academia, industry, and the general public. This paper mainly introduces the application of nanofiber materials in tissue engineering, drug release, wound dressing, and other biomedicine fields.

scholarly journals Crosslinking Collagen Constructs: Achieving Cellular Selectivity Through Modifications of Physical and Chemical Properties

2020 ◽  
Vol 10 (19) ◽  
pp. 6911
Author(s):  
Malavika Nair ◽  
Serena M. Best ◽  
Ruth E. Cameron
Keyword(s):  
Tissue Engineering ◽  
Cell Viability ◽  
Biomedical Applications ◽  
Engineering Application ◽  
Chemical Properties ◽  
Tissue Engineering Application ◽  
Physical And Chemical Properties ◽  
Crosslinking Process ◽  
Physical And Chemical ◽  
And Chemical Properties

Collagen-based constructs have emerged in recent years as ideal candidates for tissue engineering implants. For many biomedical applications, collagen is crosslinked in order to improve the strength, stiffness and stability of the construct. However, the crosslinking process may also result in unintended changes to cell viability, adhesion or proliferation on the treated structures. This review provides a brief overview of some of both the most commonly used and novel crosslinkers used with collagen, and suggests a framework by which crosslinking methods can be compared and selected for a given tissue engineering application.

Hancornia speciosa latex for biomedical applications: physical and chemical properties, biocompatibility assessment and angiogenic activity

2014 ◽  
Vol 25 (9) ◽  
pp. 2153-2162 ◽  
Author(s):  
Luciane Madureira Almeida ◽  
Juliana Ferreira Floriano ◽  
Thuanne Pires Ribeiro ◽  
Lais Nogueira Magno ◽  
Lígia Souza Lima Silveira da Mota ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Angiogenic Activity ◽  
Hancornia Speciosa ◽  
Physical And Chemical ◽  
And Chemical Properties

Recent Progress on the Synthesis and Biomedical Properties of Natural Biopolymer Composites

2020 ◽  
Vol 28 ◽  
Author(s):  
Shan Liu ◽  
Xing-Xiang Ji ◽  
Jie-Fang Zhu
Keyword(s):  
Mechanical Property ◽  
Biomedical Applications ◽  
Recent Progress ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Preparation Methods ◽  
Biopolymer Composites ◽  
Physical And Chemical ◽  
Morphology Characteristics ◽  
And Chemical Properties

Background: Natural biopolymers have drawn extensive attention because of their great biocompatibility, biodegradability, renewability, and the availability of various reactive functional groups for modifying and introducing novel components. In the last few years, numerous natural biopolymer composites have been exploited to improve their physical and chemical properties and add new functionalities. Methods: Herein, we summarize the current progress of three common classes of natural biopolymer-based composites including alginate, chitosan, and gelatin. Results: The morphology characteristics, preparation methods, and unique functionalities of these biopolymer composites are also analyzed and discussed. Results: The morphology characteristics, preparation methods, and unique functionalities of these biopolymer composites are also analyzed and discussed. Conclusion: Finally, the article offers an overview of recent progress of the main biomedical applications such as tissue engineering, wound-healing, and drug delivery, which inspires further progress of biopolymer composites with tailored mechanical property and stable characteristics for pharmaceutical and biomedical applications.

scholarly journals Melanin-Like Nanomedicine in Photothermal Therapy Applications

2021 ◽  
Vol 22 (1) ◽  
pp. 399
Author(s):  
Yale Yue ◽  
Xiao Zhao
Keyword(s):  
Photothermal Therapy ◽  
Chemical Properties ◽  
Treatment Method ◽  
The Body ◽  
Tumor Treatment ◽  
Photothermal Conversion ◽  
The Past ◽  
Internal Mechanism ◽  
Physical And Chemical ◽  
And Chemical Properties

Photothermal therapy (PTT) mediated by nanomaterial has become an attractive tumor treatment method due to its obvious advantages. Among various nanomaterials, melanin-like nanoparticles with nature biocompatibility and photothermal conversion properties have attracted more and more attention. Melanin is a natural biological macromolecule widely distributed in the body and displays many fascinating physicochemical properties such as excellent biocompatibility and prominent photothermal conversion ability. Due to the similar properties, Melanin-like nanoparticles have been extensively studied and become promising candidates for clinical application. In this review, we give a comprehensive introduction to the recent advancements of melanin-like nanoparticles in the field of photothermal therapy in the past decade. In this review, the synthesis pathway, internal mechanism and basic physical and chemical properties of melanin-like nanomaterials are systematically classified and evaluated. It also summarizes the application of melanin-like nanoparticles in bioimaging and tumor photothermal therapy (PTT)in detail and discussed the challenges they faced in clinical translation rationally. Overall, melanin-like nanoparticles still have significant room for development in the field of biomedicine and are expected to applied in clinical PTT in the future.

scholarly journals Functionalization of metal nanoclusters for biomedical applications

The Analyst ◽  
2016 ◽  
Vol 141 (11) ◽  
pp. 3126-3140 ◽  
Author(s):  
Xiao-Rong Song ◽  
Nirmal Goswami ◽  
Huang-Hao Yang ◽  
Jianping Xie
Keyword(s):  
Biomedical Applications ◽  
Chemical Properties ◽  
Physical And Chemical Properties ◽  
Metal Nanoclusters ◽  
Functional Nanomaterials ◽  
New Class ◽  
Strong Luminescence ◽  
Physical And Chemical ◽  
Homo Lumo ◽  
And Chemical Properties

Metal nanoclusters (NCs) are emerging as a new class of functional nanomaterials in the area of biological sensing, labelling, imaging and therapy due to their unique physical and chemical properties, such as ultrasmall size, HOMO–LUMO transition, strong luminescence together with good photostability and biocompatibility.

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