scholarly journals RF Remote Blood Glucose Sensor and a Microfluidic Vascular Phantom for Sensor Validation

Biosensors ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. 494
Author(s):  
Muhammad Farhan Affendi Mohamad Yunos ◽  
Rémi Manczak ◽  
Cyril Guines ◽  
Ahmad Fairuzabadi Mohd Mansor ◽  
Wing Cheung Mak ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Blood Sugar ◽  
Glucose Sensor ◽  
Blood Glucose Monitoring ◽  
Human Hand ◽  
Device Structure ◽  
Major Health Problem ◽  
Resonance Frequencies ◽  
Stepped Impedance Resonator ◽  
Sugar Levels

Diabetes has become a major health problem in society. Invasive glucometers, although precise, only provide discrete measurements at specific times and are unsuitable for long-term monitoring due to the injuries caused on skin and the prohibitive cost of disposables. Remote, continuous, self-monitoring of blood sugar levels allows for active and better management of diabetics. In this work, we present a radio frequency (RF) sensor based on a stepped impedance resonator for remote blood glucose monitoring. When placed on top of a human hand, this RF interdigital sensor allows detection of variation in blood sugar levels by monitoring the changes in the dielectric constant of the material underneath. The designed stepped impedance resonator operates at 3.528 GHz with a Q factor of 1455. A microfluidic device structure that imitates the blood veins in the human hand was fabricated in PDMS to validate that the sensor can measure changes in glucose concentrations. To test the RF sensor, glucose solutions with concentrations ranging from 0 to 240 mg/dL were injected into the fluidic channels and placed underneath the RF sensor. The shifts in the resonance frequencies of the RF sensor were measured using a network analyzer via its S11 parameters. Based on the change in resonance frequencies, the sensitivity of the biosensor was found to be 264.2 kHz/mg·dL−1 and its LOD was calculated to be 29.89 mg/dL.

scholarly journals UJI AKTIVITAS ANTIDIABETES KOMBINASI EKSTRAK ETANOL DAUN ECENG GONDOK (Eichhornia crassipes (Mart.)Solms) DAN DAUN SINTRONG (Crassocephalum crepidioides (Benth.) S. Moore) PADA MENCIT

2021 ◽  
Vol 4 (1) ◽  
pp. 44-53
Author(s):  
Andri Priyoherianto ◽  
◽  
Panji Ratih Suci ◽  
Putri Rizki Cahya Fatimah ◽  
Atik Nur Wijayanti
Keyword(s):  
Blood Glucose ◽  
Blood Sugar ◽  
Water Hyacinth ◽  
Leaf Extract ◽  
Positive Control ◽  
Negative Control ◽  
Glucose Levels ◽  
Normal Limits ◽  
Blood Glucose Levels ◽  
Sugar Levels

Diabetes mellitus is a chronic metabolic disorder that occurs due to destruction of pancreatic ? cells characterized by blood glucose levels that exceed normal limits. The purpose of this study was to determine the therapeutic effect of the combination of water hyacinth leaf extract and Sintrong leaf in reducing blood glucose levels in alloxan-induced experimental animals. Water hyacinth leaf powder and Sintrong leaves were extracted using the maceration method with 70% ethanol as a solvent. A total of 25 mice were divided into 5 groups, namely negative control CMC-Na 0.5%, positive control glibenclamide 0.00065 mg / g BW, water hyacinth leaf extract 17.5 mg / kg BW, Sintrong leaf extract 10.5 mg/ kg BW and a combination of water hyacinth leaf extract 17.5 mg / kg BW and sintrong leaf 10.5 mg / kg BW. The results showed that a single extract of water hyacinth and Sintrong leaves was able to reduce blood sugar levels for 7 days. The combination dose was effective in reducing blood sugar levels with a combination dose of 17.5 mg/ kg water hyacinth leaf extract in combination for 7 days.

The Impact of Fasting in Ramadan on Metabolic and Anthropometric Indices in Trained Type ΙΙ Diabetic Patients: A Prospective Observational Study

2020 ◽  
Author(s):  
Tayebe Yazdanyar ◽  
Mehrnoush Sohrab ◽  
Atena Ramezani ◽  
Zahra Kashi ◽  
Parastoo Karimi Ali Abadi ◽  
...  
Keyword(s):  
Blood Glucose ◽  
Observational Study ◽  
Blood Sugar ◽  
Prospective Observational Study ◽  
Eating Habits ◽  
Glucose Monitoring ◽  
Blood Glucose Monitoring ◽  
Diabetic Patients ◽  
Anthropometric Indices ◽  
Ramadan Fasting

Abstract Background: Fasting has certain effects on metabolic and anthropometric parameters in diabetic patients. It is, therefore, necessary for patients to receive proper education related to their physical activities, eating habits, blood glucose monitoring, and medications. The aim of this study was to investigate the effects of Ramadan fasting on metabolic and anthropometric indices in type ΙΙ diabetic patients.Methods: This prospective observational study was performed during Ramadan 2018. The study population consisted of diabetic patients who desired to fast and received information on physical activity, eating habits, blood glucose monitoring, and taking their medications before Ramadan. Fasting blood sugar (FBS), blood sugar 2-hour postprandial (BS2hpp), glycosylated hemoglobin (HbA1C), and the lipids profile were assessed before and after Ramadan month. FBS and BS2hpp were also evaluated on the fifteenth day of Ramadan. The significance level for data analysis was considered p<0.05.Results: Out of 40 diabetic cases who completed the study, 6 (15%) were male and 34 (75%) were female. The mean age of participants was 55.2 ± 9.3 years. The anthropometric variables, including weight, BMI, waist, and blood pressure, decreased significantly after Ramadan fasting (p<0.05). FBS decreased significantly (125.1 ± 27.4 vs 105.2 ± 21.4, p<0.0001) and serum triglyceride increased significantly (127.5 ± 45.5 vs 166.5±53.5 mg/dl, p<0.001) after fasting compared to pre-Ramadan measurement. Other variables remained unchanged.Conclusion: The results of this study indicate that type II diabetic patients who have controlled blood sugar and received information based on clinical guidelines about their lifestyle and medications can fast safely during the holy month of Ramadan.

scholarly journals THE EFFECTS OF CORN FLOUR WITH TEMPEH FLOUR SUPPLEMENTATION FEEDING IN DIABETES MELLITUS WISTAR RATS TOWARD BLOOD GLUCOSE LEVEL

2017 ◽  
Vol 4 (2) ◽  
pp. 24
Author(s):  
Fatifa Asmarani ◽  
Bambang Wirjatmadi ◽  
Merryana Adriani
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Sugar ◽  
Wistar Rats ◽  
Control Group ◽  
Standard Diet ◽  
Corn Flour ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Sugar Levels

Background: Diabetes mellitus (DM) is metabolic disorder syndrome characterized by hyperglycemia due to deficiency of insulin secretion. Patients of diabetic patients increases each year, so it needs proper handling. Corn flour is a source of carbohydrates with a low glycemic index to help reduce the rise in blood sugar levels. In addition, supplementation with tempeh flour containing isoflavones act to protect cells from free radical thereby inhibiting damage cells. Fiber in tempeh affect blood glucose levels because it slows the absorption of glucose.Objective: To determine the effect supplementation of corn flour with tempeh flour on blood sugar levels in diabetes mellitus Wistar rats.Methods: The study was true experimental design with Pre-posttest control group design, samples were 20 male Wistar rats aged 2-3 months were then divided into 4 groups (T0, T1, T2, T3.) T0 was injected with alloxan as 30 mg / 150 grams of BB rats are subsequently treated with standard diet; T1 was dministered by standard diet 50% + 50% corn flour; T2 was administered by standard diet 50% + 30% + corn flour tempeh flour 20%; and T3 was administered by standard diet of corn flour 50% + 15% + 35% tempeh flour for 2 weeks. Blood glucose levels were measured with a glucose kit (GOD FS). Research data were analyzed by One Way ANOVA followed by Tukey's Post Hoc test p-value <0.05.Results: There were significant differences on blood sugar levels in all groups (p = 0.000): control group (only dietary standards), T1 (administered by standard diet 50% + corn flour 50%), T2 (administered by a standard diet 50% + cornstarch 30% tempeh flour + 20%) and T3 (administered by standard diet of corn flour 50% + 15% + 35% tempeh flour).Conclusion: corn flour with tempeh flour supplementation effect on decresing of blood sugar levels.

scholarly journals Assessment of Cardio-metabolic Risk Factors of Pre-diabetes/Diabetes among University Students: A Cross Sectional-study at Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

2018 ◽  
pp. 1-9
Author(s):  
Bright Oppong Afranie ◽  
Sampson Donkor ◽  
Simon Koffie ◽  
Selorm Philip Segbefia ◽  
Joseph Badu Gyapong ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Glucose ◽  
Blood Sugar ◽  
Prevalence Rate ◽  
Metabolic Risk Factors ◽  
Fasting Blood Sugar ◽  
Metabolic Risk ◽  
Glucose Levels ◽  
Kwame Nkrumah ◽  
Sugar Levels

Introduction: Diabetes is one of the most common chronic diseases globally and its complications include retinopathy, nephropathy and neuropathy. Early detection of the risk factors and management of pre-diabetes can however reduce the risk of developing diabetes-related complications. Objective: This study was undertaken to assess cardio-metabolic risk factors for diabetes among undergraduate students at KNUST. Method: The study was carried out at the Kwame Nkrumah University of Science and Technology at Kumasi, from January 2017 to March 2017. Questionnaires were administered to 500 participants (45% males and 55% females) to obtain demographic and anthropometric data, information on physical activity, and knowledge on diabetes. About 5 ml of venous blood was taken from participants after an overnight fast to determine fasting plasma glucose (FPG) and lipid profile. Results: The mean age of participants were 21±2.40 years and 19.24±2.42 years for male and female respectively. Prevalence rate of pre-diabetes was 5% in this study. Mean values of systolic pressure (p<0.001) and blood glucose level (p=0.042) were significantly higher in men than the females. There was a significant association between the total cholesterol and the fasting blood sugar levels among participants (p=0.045). LDL-cholesterols concentrations were also significantly associated with blood sugar levels among participants (p<0.001). Risk factors such physical exercise (p<0.001) and family history (p<0.001) if diabetes were significantly associated with fasting blood glucose levels of participants. Obesity was no associated with serum glucose levels among participants in this study (p=0.533). HDL-cholesterol was inversely correlated with Fasting blood sugar even though it was no significant (r=-0.240, p=0.430). Conclusion: The prevalence rate of pre-diabetes was 5% in this study. Education about the disease as well as appropriate modification of lifestyle can help reduce the incidence of diabetes and its associated risk factors. 

scholarly journals Waist Circumference as The Strongest Factor Related to Blood Glucose Level

2014 ◽  
Vol 2 (1) ◽  
pp. 48
Author(s):  
Nenni Septyaningrum ◽  
Santi Martini
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Blood Glucose Level ◽  
Blood Sugar ◽  
Body Mass ◽  
Glucose Level ◽  
Abdominal Obesity ◽  
Waist Hip Ratio ◽  
Sugar Levels

ABSTRACTThe increasing prevalence of overweight and obesity is associated with the increasing incident of type 2 diabetes mellitus. Obesity, especially abdominal obesity is an important risk factor for the onset of diabetes. The objective of this study was to determine the relationship between body mass index, waist circumference and waist hip ratio with blood glucose level. The study design was cross-sectional. The study population was elderly posyandu member aged 45 to 70 years in Menur clinic work area who were registered in elderly posyandu activities in May 2013. The numbers of sample were 60 respondents who drawn by simple random sampling method. The variabels of this study were the characteristics of respondent, body mass index, waist  circumference,  waist hip ratio and fasting blood glucose level. The study showed that respondents classified as overweight (38%), obesity (33, 3%), abdominal obesity based on waist circumference  (77.8%), abdominal obesity based on waist hip ratio (81,7 %) and blood glucose level more than 125 mg/dl (8.3%). Pearson correlation test showed that there was relationship between body mass index with blood sugar levels (p=0,007; r=0,345), between waist circumference with blood sugar levels (p=0,001; r=0,424) and  between waist hip ratio with blood sugar levels (p =0,002; r=0,392). Waist circumference as the strongest factor related to blood glucose level. Waist circumference measurement should be done in elderly posyandu activities to detect high-risk individuals with diabetes. Keywords: Diabetes, body mass index, waist circumference, waist hip ratio,                     blood glucose level

scholarly journals EFFECT OF HESPERETIN TREATMENT ON BLOOD GLUCOSE LEVEL, SPERMATOZOA QUALITY, AND SPERMATOZOA QUANTITY IN ALLOXAN-INDUCED DIABETIC MICE

2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Nerdy Nerdy ◽  
Linta Meliala ◽  
Bunga Rimta Barus ◽  
Puji Lestari ◽  
Selamat Ginting ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Blood Sugar ◽  
Normal Control ◽  
Normal Control Group ◽  
Optimum Dose ◽  
Control Group ◽  
Testicular Weight ◽  
Significant Difference ◽  
Sugar Levels

Male infertility has occurred rapidly in the last few decades, primarily in developing countries. An antioxidant, hesperetin is a flavonoid that is found in abundance in orange peels. The aims of this research were to determine the effect of hesperetin on blood sugar levels, spermatozoaquality, and spermatozoa quantity. The research structure included induction of diabetes mellitus and treatment for 8 weeks, followed bydetermination of blood sugar levels, spermatozoa quality, and spermatozoa quantity. Hesperetin has the ability to restore blood sugar levels, spermatozoa quantity, seminiferous tubules diameter, and testicular weight, volume, and germinal epithelial layer thickness with significant difference from the normal control group. Hesperetin did not fully restore spermatozoa motility, viability, and morphology with significant difference from the normal control group, nor from the positive control group. However, overall, hesperetin decreased blood glucose levels, increased spermatozoa quantity, and improved the spermatozoa quality in alloxan-induced diabetes mellitus mice. Dose-dependent activity was observed with the optimum dose at 200 mg/kg body weight.

scholarly journals Korelasi Lingkar Pinggang dengan Kadar Gula Darah Puasa, Kadar Trigliserida, dan Tekanan Darah pada Mahasiswa Fakultas Kedokteran Universitas HKBP Nommensen

2021 ◽  
Vol 3 (2) ◽  
pp. 08-13
Author(s):  
Ervina Julien Sitanggang
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Young Adults ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Blood Sugar ◽  
Fasting Blood Glucose ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Sugar Levels

Introduction: Cardiovascular disease is the number one cause of death globally with an incidence of adolescents and young adults in Indonesia as many as 153.705 cases. Central obesity is associated with the risk of cardiovascular disease due to increase in fasting blood glucose levels, cholesterol and triglyceride levels, and blood pressure. Aims: to determine the correlation between waist circumference and fasting blood glucose levels, triglyceride levels, and blood pressure in young adults. Method: This analytic study with a cross-sectional approach involved 53 young adult subjects (18-25 years old). Waist circumference is measured using a tape measure. Blood sugar and triglyceride levels were measured using Cobas® 6000 analyzer machine from blood samples of subjects after fasting for 8-12 hours. Blood pressure data are obtained by measurement using aneroid sphygmomanometer. Results: In this study, the mean waist circumference of the research subjects was 77,4 cm. No correlation was found between waist circumference and fasting blood sugar levels (p = 0,159). However, a positive correlation was found between waist circumference and triglyceride levels (p = 0,008; r = 0,332), between waist circumference and systolic blood pressure (p = 0,049; r = 0,230), and between waist circumference and diastolic blood pressure (p = 0,017; r = 0,293). Conclusion: waist circumference is positively correlated with triglyceride levels and blood pressure, but does not correlate with fasting blood sugar levels.

scholarly journals The CORRELATION OF BLOOD SUGAR LEVELS WITH THE ELASTICITY OF CORONARY ARTERIES

2019 ◽  
Vol 3 (1) ◽  
pp. 1-6
Author(s):  
INDAH ROHMAWATI ◽  
Dora Dayu Rahma Turista
Keyword(s):  
Blood Glucose ◽  
Blood Sugar ◽  
Coronary Arteries ◽  
P Value ◽  
Cross Sectional ◽  
High Blood Glucose ◽  
Magnetic Analyzer ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Sugar Levels

Coronary arteries are blood vessels that carry oxygen and nutrients to the heart muscle. These vessels can experience constriction due to the accumulation of plaque which causes atherosclerosis. Atherosclerosis is characterized by reduced coronary artery elasticity. Blood glucose levels are one of the factors that cause atherosclerosis. The aims of this study was to determine whether there was a correlation of blood sugar levels with the elasticity of coronary arteries. This study is an analytical study with cross sectional design. The population in this study were all patients who visited the Gipateda Tulungagung treatment clinic that was more than 30 years old and female. Through accidental sampling technique, 30 respondents were obtained. The study was conducted from March 1, 2016 to May 1, 2016. Data was collected using a quantum resonance magnetic analyzer (QMRA) to determine the value of blood sugar levels and the value of elasticity of coronary arteries. The data obtained were analyzed statistically by bivariate linear regression tests to determine whether there was a significant correlation of blood sugar levels with the elasticity of coronary arteries. The results showed that the p value is 0.000 < 0.05, which means that there was a significant correlation between blood sugar levels and the elasticity of the coronary arteries. High blood glucose levels can damage the vascular endothelium and also increasing platelet agegrat, so that can resulting atherosclerosis. Every individual should be able to control blood sugar levels with a healthy lifestyle and early detection regularly to prevent the decrease of coronary arteries elasticity because that can lead to coronary heart disease (CHD).

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