scholarly journals Assessment of Cardio-metabolic Risk Factors of Pre-diabetes/Diabetes among University Students: A Cross Sectional-study at Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

Author(s):  
Bright Oppong Afranie ◽  
Sampson Donkor ◽  
Simon Koffie ◽  
Selorm Philip Segbefia ◽  
Joseph Badu Gyapong ◽  
...  

Introduction: Diabetes is one of the most common chronic diseases globally and its complications include retinopathy, nephropathy and neuropathy. Early detection of the risk factors and management of pre-diabetes can however reduce the risk of developing diabetes-related complications. Objective: This study was undertaken to assess cardio-metabolic risk factors for diabetes among undergraduate students at KNUST. Method: The study was carried out at the Kwame Nkrumah University of Science and Technology at Kumasi, from January 2017 to March 2017. Questionnaires were administered to 500 participants (45% males and 55% females) to obtain demographic and anthropometric data, information on physical activity, and knowledge on diabetes. About 5 ml of venous blood was taken from participants after an overnight fast to determine fasting plasma glucose (FPG) and lipid profile. Results: The mean age of participants were 21±2.40 years and 19.24±2.42 years for male and female respectively. Prevalence rate of pre-diabetes was 5% in this study. Mean values of systolic pressure (p<0.001) and blood glucose level (p=0.042) were significantly higher in men than the females. There was a significant association between the total cholesterol and the fasting blood sugar levels among participants (p=0.045). LDL-cholesterols concentrations were also significantly associated with blood sugar levels among participants (p<0.001). Risk factors such physical exercise (p<0.001) and family history (p<0.001) if diabetes were significantly associated with fasting blood glucose levels of participants. Obesity was no associated with serum glucose levels among participants in this study (p=0.533). HDL-cholesterol was inversely correlated with Fasting blood sugar even though it was no significant (r=-0.240, p=0.430). Conclusion: The prevalence rate of pre-diabetes was 5% in this study. Education about the disease as well as appropriate modification of lifestyle can help reduce the incidence of diabetes and its associated risk factors. 

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Hindri Djakani ◽  
Theresia Masinem ◽  
Yanti M.` Mewo

Abstract: Glucose is a universal fuel of human cells and functions as a source of carbon for the synthesis of most of other compounds. Blood glucose level is used as a parameter of the successful metabolism in the body. In certain circumstances with respect to the blood glucose levels in the body, hypoglycemia or hyperglycemia can occur.  The aim of this study was to find out a profile of fasting blood sugar levels (FBS) in males aged 40-59. The method used was consecutive sampling with the number of subjects was as many as 46 males who lived in Malalayang Manado. Of the 46 subjects, there were three who did not meet the criteria. The results of this study showed that four subjects had low levels of FBS, four subjects had high FBS, and 35 subjects had normal FBS. Conclusion: In this study most males aged 40-59 years who lived in Malalayang Manado had normal fasting blood sugar levels. Key words: males, fasting blood sugar     Abstrak: Glukosa merupakan bahan bakar universal bagi sel-sel tubuh manusia dan merupakan sumber karbon untuk sintesis sebagian besar senyawa lainnya. Kadar glukosa dipergunakan sebagai parameter keberhasilan metabolisme dalam tubuh. Dalam keadaan tertentu sehubungan dengan kadar glukosa di dalam tubuh, dapat terjadi hipoglikemia atau hiperglikemia. Penelitian ini bertujuan untuk mengetahui gambaran kadar gula darah puasa (GDP) pada laki-laki berusia 40-59 tahun. Metode yang digunakan ialah consecutive sampling dengan jumlah subjek sebanyak 46 orang yang berdomisili di Kecamatan Malalayang Manado. Dari 46 subjek, terdapat tiga orang yang tidak memenuhi criteria. Hasil penelitian memeperlihatkan empat subjek memiliki kadar GDP rendah, empat subjek memiliki kadar GDP tinggi, dan 35 subjek memiliki GDP normal. Simpulan: Dalam penelitian ini sebagian besar laki-laki berusia 40-59 tahun yang berdomisili di Malalayang memiliki kadar gula darah puasa normal. Kata kunci: laki-laki, kadar gula darah puasa


2021 ◽  
Vol 14 ◽  
pp. 117863882110352
Author(s):  
Yordanos Mengistu ◽  
Gobena Dedefo ◽  
Mesay Arkew ◽  
Gebeyehu Asefa ◽  
Gutema Jebessa ◽  
...  

Background: Khat chewing is a long standing social-cultural habit in several countries. Even though many people chew khat simply for its pleasurable and stimulatory effect, evidence showed widely-held belief among khat chewers in Ethiopia and other part of the world that khat helps to lower blood glucose while some studies are contradicted on the effect of khat. There is limited data about khat’s effect on blood glucose especially in our setting, Harar estern Ethiopia. Objective: Primarily the present study aims to compare fasting blood sugar level among khat chewer diabetic and healthy individuals, and to asses risk factors associated with poor glycemic control in diabetic subjects. Method: A cross-sectional study included 200 confirmed diabetic and healthy subjects. Fasting blood sugar was determined by enzymatic method glucose oxidase and glucose hexokinase. Glycemic control was also determined for diabetic subjects based on the last 2-month diabetic clinic visits and current measurement. Result: (Median ± IQR [interquartile range]) fasting blood sugar difference among Khat chewer and non khat chewer were 159 ± 83 mg/dl and 202 ± 79 mg/dl respectively in diabetic subjects when tested by glucose oxidase. Similarly, in healthy non khat chewer and khat chewer, khat chewers has lower (Median ± IQR) fasting blood glucose level 82 ± 18 mg/dl than non khat chewers 94 ± 13 mg/dl when tested by glucose oxidase. Regarding risk factors associated with poor glycemic control in diabetic subjects, positive parental diabetes history, insulin medication, being overweight, obese were significantly associated with poor glycemic control. Conclusion: There was significant effect of khat on median FBS among khat chewers in diabetic and healthy individuals. And the proportion of glycemic control was high among diabetic subjects. Recommendation: Health care professional and patients should manage the risk factors to delay disease progression and restrain the damage. More studies should be conducted in randomized control trial manner to further elucidate khat effect on blood sugar level so that the actual effect of khat can be identified unlike in cross sectional where there may not be strong causal relationship.


2021 ◽  
Vol 4 (1) ◽  
pp. 44-53
Author(s):  
Andri Priyoherianto ◽  
◽  
Panji Ratih Suci ◽  
Putri Rizki Cahya Fatimah ◽  
Atik Nur Wijayanti

Diabetes mellitus is a chronic metabolic disorder that occurs due to destruction of pancreatic ? cells characterized by blood glucose levels that exceed normal limits. The purpose of this study was to determine the therapeutic effect of the combination of water hyacinth leaf extract and Sintrong leaf in reducing blood glucose levels in alloxan-induced experimental animals. Water hyacinth leaf powder and Sintrong leaves were extracted using the maceration method with 70% ethanol as a solvent. A total of 25 mice were divided into 5 groups, namely negative control CMC-Na 0.5%, positive control glibenclamide 0.00065 mg / g BW, water hyacinth leaf extract 17.5 mg / kg BW, Sintrong leaf extract 10.5 mg/ kg BW and a combination of water hyacinth leaf extract 17.5 mg / kg BW and sintrong leaf 10.5 mg / kg BW. The results showed that a single extract of water hyacinth and Sintrong leaves was able to reduce blood sugar levels for 7 days. The combination dose was effective in reducing blood sugar levels with a combination dose of 17.5 mg/ kg water hyacinth leaf extract in combination for 7 days.


2012 ◽  
Vol 24 (5) ◽  
pp. 812-826 ◽  
Author(s):  
Martin Sénéchal ◽  
Isabelle J. Dionne ◽  
Martin Brochu

Objectives: To investigate the additive effect of dynapenia and abdominal obesity on metabolic risk factors in older adults. Method: A total of 3,007 men and women from the National Health and Nutrition Examination Survey (NHANES) study were categorized as follows: (a) non-dynapenic/non-abdominally obese (N-DYN/N-AO), (b) dynapenic/non-abdominally obese (DYN/N-AO), (c) non-dynapenic/abdominally obese (N-DYN/AO), (d) dynapenic/ abdominally obese (DYN/AO) based on waist circumference (WC) and leg muscle strength tertiles. Dependent variables were lipids, glucose, blood pressure, and other chronic conditions. Results: The DYN/AO group had lower plasma HDL-chol and higher triglyceride and glucose levels than N-DYN/N-AO and DYN/N-AO groups (all p ≤ .01). Higher plasma triglyceride was observed in the DYN/AO group compared with N-DYN/AO group ( p ≤ .01). The odds of having metabolic syndrome, cardiovascular diseases, and type II diabetes were higher in DYN/AO compared with DYN/N-AO and N-DYN/N-AO. Conclusion: DYN/AO older adults might be at greater risk of metabolic alterations than those displaying dynapenia alone or those with neither abdominal obesity nor dynapenia.


2013 ◽  
Vol 30 (1) ◽  
pp. 21-30
Author(s):  
Veroslava Stanković ◽  
Svetlana Stojanović ◽  
Nađa Vasiljević

Summary People with metabolic syndrome (MetSy) are about twice as likely to develop cardiovascular disease and over four times as likely to develop type 2 diabetes compared to subjects without metabolic syndrome. Waist circumferences (WC) and body mass index (BMI) are useful screening tools for making the diagnosis. MetSy has increased the health risk in primary care. The aim of the study was to evaluate the anthropometric indices for MetSy and determine which of simple anthropometric measurements is most closely associated with metabolic risk factors. The research included 264 individuals, of which 132 men with mean age (±SD) of 44.73 ±9.37 years and 132 women with mean age (±SD) of 46.67±8.44 years. Antropometric indicators were measured using standard protocols, without shoes and outerwear. BMI was calculated as weight/height2(kg/m2) ratio, as recommended by the World Health Organization (WHO). Blood pressure measurements were obtained with the subject in a seated position by using a standard mercury sphygmomanometer. Blood samples were obtained after a minimum of 12-h fast; the metabolic parameters (high-density lipoprotein-cholesterol, low-density lipoprotein-cholesterol, triglycerides, blood glucose) were analyzed by standard procedures. Analysis of the examinees’ medical records was also performed. Metabolic syndrome was diagnosed using the International Diabetes Federation (IDF) criteria. The analysis of the research results were performed using the Statistical Package for Social Science version 10.0 (SPSS 10.0 for Windows). The prevalence of the metabolic syndrome was 44.7% in men and 43.2% in women. Normal-weight subjects of both sexes were significantly younger and had significantly lower blood glucose, total cholesterol, LDL and triglycerides than overweight and obese subjects. Systolic and diastolic blood pressure values were significantly increased in parallel with increasing of BMI. For the whole sample, both anthropometric indices had significant associations with the other five components of MetSy. Waist circumference is a simple measure of adiposity most strongly associated with metabolic abnormalities. The results obtained in this study indicate that WC is a good indicator of health risk in women but not in men. Measurement of WC by BMI categories may indicate a person with an increased risk of development of chronic diseases.


2017 ◽  
Vol 4 (2) ◽  
pp. 24
Author(s):  
Fatifa Asmarani ◽  
Bambang Wirjatmadi ◽  
Merryana Adriani

Background: Diabetes mellitus (DM) is metabolic disorder syndrome characterized by hyperglycemia due to deficiency of insulin secretion. Patients of diabetic patients increases each year, so it needs proper handling. Corn flour is a source of carbohydrates with a low glycemic index to help reduce the rise in blood sugar levels. In addition, supplementation with tempeh flour containing isoflavones act to protect cells from free radical thereby inhibiting damage cells. Fiber in tempeh affect blood glucose levels because it slows the absorption of glucose.Objective: To determine the effect supplementation of corn flour with tempeh flour on blood sugar levels in diabetes mellitus Wistar rats.Methods: The study was true experimental design with Pre-posttest control group design, samples were 20 male Wistar rats aged 2-3 months were then divided into 4 groups (T0, T1, T2, T3.) T0 was injected with alloxan as 30 mg / 150 grams of BB rats are subsequently treated with standard diet; T1 was dministered by standard diet 50% + 50% corn flour; T2 was administered by standard diet 50% + 30% + corn flour tempeh flour 20%; and T3 was administered by standard diet of corn flour 50% + 15% + 35% tempeh flour for 2 weeks. Blood glucose levels were measured with a glucose kit (GOD FS). Research data were analyzed by One Way ANOVA followed by Tukey's Post Hoc test p-value <0.05.Results: There were significant differences on blood sugar levels in all groups (p = 0.000): control group (only dietary standards), T1 (administered by standard diet 50% + corn flour 50%), T2 (administered by a standard diet 50% + cornstarch 30% tempeh flour + 20%) and T3 (administered by standard diet of corn flour 50% + 15% + 35% tempeh flour).Conclusion: corn flour with tempeh flour supplementation effect on decresing of blood sugar levels.


2021 ◽  
Vol 3 (2) ◽  
pp. 08-13
Author(s):  
Ervina Julien Sitanggang

Introduction: Cardiovascular disease is the number one cause of death globally with an incidence of adolescents and young adults in Indonesia as many as 153.705 cases. Central obesity is associated with the risk of cardiovascular disease due to increase in fasting blood glucose levels, cholesterol and triglyceride levels, and blood pressure. Aims: to determine the correlation between waist circumference and fasting blood glucose levels, triglyceride levels, and blood pressure in young adults. Method: This analytic study with a cross-sectional approach involved 53 young adult subjects (18-25 years old). Waist circumference is measured using a tape measure. Blood sugar and triglyceride levels were measured using Cobas® 6000 analyzer machine from blood samples of subjects after fasting for 8-12 hours. Blood pressure data are obtained by measurement using aneroid sphygmomanometer. Results: In this study, the mean waist circumference of the research subjects was 77,4 cm. No correlation was found between waist circumference and fasting blood sugar levels (p = 0,159). However, a positive correlation was found between waist circumference and triglyceride levels (p = 0,008; r = 0,332), between waist circumference and systolic blood pressure (p = 0,049; r = 0,230), and between waist circumference and diastolic blood pressure (p = 0,017; r = 0,293). Conclusion: waist circumference is positively correlated with triglyceride levels and blood pressure, but does not correlate with fasting blood sugar levels.


Author(s):  
INDAH ROHMAWATI ◽  
Dora Dayu Rahma Turista

Coronary arteries are blood vessels that carry oxygen and nutrients to the heart muscle. These vessels can experience constriction due to the accumulation of plaque which causes atherosclerosis. Atherosclerosis is characterized by reduced coronary artery elasticity. Blood glucose levels are one of the factors that cause atherosclerosis. The aims of this study was to determine whether there was a correlation of blood sugar levels with the elasticity of coronary arteries. This study is an analytical study with cross sectional design. The population in this study were all patients who visited the Gipateda Tulungagung treatment clinic that was more than 30 years old and female. Through accidental sampling technique, 30 respondents were obtained. The study was conducted from March 1, 2016 to May 1, 2016. Data was collected using a quantum resonance magnetic analyzer (QMRA) to determine the value of blood sugar levels and the value of elasticity of coronary arteries. The data obtained were analyzed statistically by bivariate linear regression tests to determine whether there was a significant correlation of blood sugar levels with the elasticity of coronary arteries. The results showed that the p value is 0.000 < 0.05, which means that there was a significant correlation between blood sugar levels and the elasticity of the coronary arteries. High blood glucose levels can damage the vascular endothelium and also increasing platelet agegrat, so that can resulting atherosclerosis. Every individual should be able to control blood sugar levels with a healthy lifestyle and early detection regularly to prevent the decrease of coronary arteries elasticity because that can lead to coronary heart disease (CHD).


2017 ◽  
Vol 2 (1) ◽  
pp. 5
Author(s):  
Ludiana Ludiana

Diabetes mellitus is a chronic metabolic disorder marked increase in blood glucose. According to the World Health Organization (WHO) in 2013 the incidence of diabetes mellitus in the world reached 347 million people in Indonesia alone ranks among the seven countries with the highest diabetes prevalence of 7.6 million people. Among the causes of the increase in blood glucose levels in diabetics is due to psychological factors, namely anxiety. In the pre-survey results in Puskesmas Sumbersari Bantul note that from 8 patients with diabetes mellitus, there are 6 people experiencing anxiety and 2 do not complain any signs of anxiety. The purpose of this study was to determine the relationship of anxiety with blood glucose levels of diabetics mellitus in Puskesmas Sumbersari Bantul District of South Metro City. The type quantitative research, form design used is cross sectional. The population in this study are patients with diabetes mellitus in Puskesmas Sumbersari Bantul District of South Metro totaling 408 samples taken as many as 41 people. The analysis in this study using the test Person Product Moment. Statistical analysis showed that anxiety patients with diabetes mellitus are at an average score of 27.44 with a standard deviation of 4.353 and the average blood sugar levels of people with diabetes mellitus are at 339.78 mg / dL with a standard deviation of 74.742. In the Person Product Moment test results proved no relationship anxiety with blood sugar levels of people with diabetes mellitus (p-value = 0.000 <a 0.05). Pearson correlation results obtained value of 0.817 towards a positive correlation with the strength of the relationship is very strong. Conclusions research shows there is an anxiety relationship with blood glucose levels of diabetics mellitus.


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