scholarly journals Sputter-Deposited Ag Nanoparticles on Electrospun PCL Scaffolds: Morphology, Wettability and Antibacterial Activity

Coatings ◽  
2021 ◽  
Vol 11 (3) ◽  
pp. 345
Author(s):  
Daniele Valerini ◽  
Loredana Tammaro ◽  
Roberta Vitali ◽  
Gloria Guillot ◽  
Antonio Rinaldi
Keyword(s):  
Ag Nanoparticles ◽  
Food Packaging ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Deposition Process ◽  
Polymer Fibers ◽  
Antibacterial Action ◽  
Porous Scaffolds ◽  
Electrospinning Technique ◽  
Sputtering Deposition

Porous scaffolds made of biocompatible and environmental-friendly polymer fibers with diameters in the nano/micro range can find applications in a wide variety of sectors, spanning from the biomedical field to textiles and so on. Their development has received a boost in the last decades thanks to advances in the production methods, such as the electrospinning technique. Conferring antimicrobial properties to these fibrous structures is a primary requirement for many of their applications, but the addition of antimicrobial agents by wet methods can present a series of drawbacks. In this work, strong antibacterial action is successfully provided to electrospun polycaprolactone (PCL) scaffolds by silver (Ag) addition through a simple and flexible way, namely the sputtering deposition of silver onto the PCL fibers. SEM-EDS analyses demonstrate that the polymer fibers get coated by Ag nanoparticles without undergoing any alteration of their morphological integrity upon the deposition process. The influence on wettability is evaluated with polar (water) and non-polar (diiodomethane) liquids, evidencing that this coating method allows preserving the hydrophobic character of the PCL polymer. Excellent antibacterial action (reduction > 99.995% in 4 h) is demonstrated against Escherichia coli. The easy fabrication of these PCL-Ag mats can be applicable to the production of biomedical devices, bioremediation and antifouling systems in filtration, personal protective equipment (PPE), food packaging materials, etc.

scholarly journals Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action

2020 ◽  
Vol 11 ◽  
pp. 1450-1469
Author(s):  
Matías Guerrero Correa ◽  
Fernanda B Martínez ◽  
Cristian Patiño Vidal ◽  
Camilo Streitt ◽  
Juan Escrig ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Food Packaging ◽  
Antimicrobial Agents ◽  
Cell Damage ◽  
Metal Oxide Nanoparticles ◽  
High Surface ◽  
Antimicrobial Properties ◽  
Antimicrobial Action ◽  
Oxide Nanoparticles ◽  
Synthesis Methods

The investigation of novel nanoparticles with antimicrobial activity has grown in recent years due to the increased incidence of nosocomial infections occurring during hospitalization and food poisoning derived from foodborne pathogens. Antimicrobial agents are necessary in various fields in which biological contamination occurs. For example, in food packaging they are used to control food contamination by microbes, in the medical field the microbial agents are important for reducing the risk of contamination in invasive and routine interventions, and in the textile industry, they can limit the growth of microorganisms due to sweat. The combination of nanotechnology with materials that have an intrinsic antimicrobial activity can result in the development of novel antimicrobial substances. Specifically, metal-based nanoparticles have attracted much interest due to their broad effectiveness against pathogenic microorganisms due to their high surface area and high reactivity. The aim of this review was to explore the state-of-the-art in metal-based nanoparticles, focusing on their synthesis methods, types, and their antimicrobial action. Different techniques used to synthesize metal-based nanoparticles were discussed, including chemical and physical methods and “green synthesis” methods that are free of chemical agents. Although the most studied nanoparticles with antimicrobial properties are metallic or metal-oxide nanoparticles, other types of nanoparticles, such as superparamagnetic iron-oxide nanoparticles and silica-releasing systems also exhibit antimicrobial properties. Finally, since the quantification and understanding of the antimicrobial action of metal-based nanoparticles are key topics, several methods for evaluating in vitro antimicrobial activity and the most common antimicrobial mechanisms (e.g., cell damage and changes in the expression of metabolic genes) were discussed in this review.

scholarly journals Rheological and Antimicrobial Properties of Chitosan and Quinoa Protein Filmogenic Suspensions with Thyme and Rosemary Essential Oils

Foods ◽  
2020 ◽  
Vol 9 (11) ◽  
pp. 1616
Author(s):  
Monserrat Escamilla-García ◽  
Raquel A. Ríos-Romo ◽  
Armando Melgarejo-Mancilla ◽  
Mayra Díaz-Ramírez ◽  
Hilda M. Hernández-Hernández ◽  
...  
Keyword(s):  
Essential Oils ◽  
Food Packaging ◽  
Antimicrobial Agents ◽  
Negative Impact ◽  
Micrococcus Luteus ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Rheological Parameters ◽  
Force Microscopy ◽  
Synthetic Materials

Food packaging faces the negative impact of synthetic materials on the environment, and edible coatings offer one alternative from filmogenic suspensions (FS). In this work, an active edible FS based on chitosan (C) and quinoa protein (QP) cross-linked with transglutaminase was produced. Thyme (T) and rosemary (R) essential oils (EOs) were incorporated as antimicrobial agents. Particle size, Z potential, and rheological parameters were evaluated. The antimicrobial activity against Micrococcus luteus (NCIB 8166) and Salmonella sp. (Lignieres 1900) was monitored using atomic force microscopy and image analysis. Results indicate that EOs incorporation into C:QP suspensions did not affect the Z potential, ranging from −46.69 ± 3.19 mV to −46.21 ± 3.83 mV. However, the polydispersity index increased from 0.51 ± 0.07 to 0.80 ± 0.04 in suspensions with EO. The minimum inhibitory concentration of active suspensions against Salmonella sp. was 0.5% (v/v) for thyme and 1% (v/v) for rosemary. Entropy and fractal dimension of the images were used to confirm the antimicrobial effect of EOs, which modified the surface roughness.

scholarly journals Natural Antimicrobials as Additives for Edible Food Packaging Applications: A Review

Foods ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 2282
Author(s):  
Sneh Punia Punia Bangar ◽  
Vandana Chaudhary ◽  
Neha Thakur ◽  
Priyanka Kajla ◽  
Manoj Kumar ◽  
...  
Keyword(s):  
Food Packaging ◽  
Antimicrobial Agents ◽  
Inhibitory Concentration ◽  
Antimicrobial Properties ◽  
Edible Films ◽  
Natural Antimicrobial ◽  
Potential Applications ◽  
Edible Packaging ◽  
Vegetables And Fruits

Edible packaging is a swiftly emerging art of science in which edible biopolymers like lipids, polysaccharides, proteins, resins, etc., and other consumable constituents extracted from various non-conventional sources are used alone or imbibed together. Edible packaging with antimicrobial components had led to the development of the hypothesis of active packaging which safeguards the quality of foods as well as health of consumers. Natural antimicrobial agents (NAMAs) like essential oils from spices, bioactive compounds derived from vegetables and fruits, animal and microorganism derived compounds having antimicrobial properties can be potentially used in edible films as superior replcement for synthetic compounds, thus serving the purpose of quality and heath. Most of the natural antimicrobial agents enjoy GRAS status and are safer than their synthetic counterparts. This review focuses on updated literature on the sources, properties and potential applications of NAMAs in the food industry. This review also analyzes the biodegradability and biocompatibility and edibility properties of NAMAs enriched films and it can be concluded that NAMAs are better substitutes but affect the organoleptic as well as the mechanical properties of the films. Despite many advantages, the inclusion of NAMAs into the films needs to be investigated more to quantify the inhibitory concentration without affecting the properties of films and exerting potential antimicrobial action to ensure food safety.

scholarly journals Active Polypropylene-Based Films Incorporating Combined Antioxidants and Antimicrobials: Preparation and Characterization

Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 722
Author(s):  
Seyed Hadi Peighambardoust ◽  
Seyedeh Homa Fasihnia ◽  
Seyed Jamaleddin Peighambardoust ◽  
Mirian Pateiro ◽  
Rubén Domínguez ◽  
...  
Keyword(s):  
Food Packaging ◽  
Antimicrobial Agents ◽  
Radical Scavenging ◽  
Antimicrobial Properties ◽  
Butylated Hydroxytoluene ◽  
Bacteria Growth ◽  
Gram Positive Bacteria ◽  
Uniform Dispersion ◽  
Physical Mixing ◽  
The Fourier Transform

Development of polypropylene (PP) films incorporating antioxidant-antimicrobial agents can inhibit microbial growth and reduce undesirable deteriorating reactions and can preserve the quality of food. This study was aimed to use a combination of sorbic acid (SA), butylated hydroxyanisole (BHA), and butylated hydroxytoluene (BHT) to provide a synergistic effect at their reduced concentrations. A Combination of the additives was more effective in enhancing mechanical properties compared to their single state in film composition. The PP-2%SA-3%BHA film (T3) had the highest tensile strength (17.9 MPa) and the lowest elongation at break (7.1%) than other films. The fourier-transform infrared (FTIR) proposed physical mixing of active additives within PP-matrix. Scanning electron microscopy showed uniform dispersion of the additives in PP-2%SA-1%BHT-1%BHA film (T4) compared to others. BHT containing films decreased the storage and loss moduli leading to weakening of film viscoelastic behaviour and reducing film melting point. The prepared active films showed higher antioxidant activity than control PP-film following an order of T4 > T2 > T3 corresponding to DPPH radical scavenging values of 89.1, 83.4 and 79.1%, respectively. All active films inhibited gram-negative and gram-positive bacteria growth. The results of this study indicated that the prepared active films possess desirable mechanical, thermal, antioxidant and antimicrobial properties enabling their use in food packaging.

scholarly journals Antimicrobial agents from Malaysian plants and their potential use in food packaging material: Review

2017 ◽  
Vol 19 ◽  
pp. 57 ◽  
Author(s):  
FA Mustapha ◽  
J Jai ◽  
F Hamidon ◽  
ZI Md Sharif ◽  
N Mohd Yusof
Keyword(s):  
Antimicrobial Agent ◽  
Food Packaging ◽  
Chemical Engineering ◽  
Antimicrobial Agents ◽  
Defense Mechanism ◽  
Antimicrobial Properties ◽  
Edible Films ◽  
Main Role ◽  
Engineering Research ◽  
Medicinal Properties

<p>Malaysia is among 12 countries in the world that rich in biodiversity including an assortment of plants with potential sources for new antimicrobial agents. Despite the fact that various plants have been screened, the requirement for detail study on antimicrobial compounds from plants is preceded as safer and better agent to inhibit growth of microbes. Therefore, selected Malaysia plants with medicinal properties are listed for further review in their antimicrobial activity and their major compound that act as antimicrobial agent. The major groups of the antimicrobial constituents are phenolics, phenolic acids, quinones, saponins, flavonoids, tannins, coumarins, terpenoids and alkaloids. These compounds are secondary metabolites that play the main role in plant defense mechanism. They also exhibited inhibitory effect on various microorganisms such as <em>Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli </em>and <em>Candida albicans</em>. Compounds derived from Malaysian plants have the potential to be used as antimicrobial additive as most of their extracts containing active compounds such as caffeic acid, pyrogallol, catechin and curcumin. Extraction method of plants extract is done either by conventional method of maceration and extraction under reflux and steam distillation or modern method of microwave assisted extraction, supercritical fluid extraction and ultrasound-assisted solvent extraction. Even though plants extracts with medicinal properties are gaining fame for their antimicrobial properties, however the study on incorporation of the extracts into edible films as antimicrobial food packaging is limited. The advantages of using an edible film with antimicrobial agent plants for food products are it safe to use and it able to extend the shelf life while reducing packaging waste.</p><p>Chemical Engineering Research Bulletin 19(2017) 57-66</p><strong></strong>

scholarly journals Rheological and Antimicrobial Properties of Silica and silver Nanoparticles-reinforced K-carrageenan/hydroxyethyl Cellulose Composites for Food Packaging Applications

2021 ◽  
Author(s):  
Balasubramanian Rukmanikrishnan ◽  
Srinivasan Ramalingam ◽  
Sam Soo Kim ◽  
Jaewoong Lee
Keyword(s):  
Ag Nanoparticles ◽  
Food Packaging ◽  
Loss Modulus ◽  
Antimicrobial Properties ◽  
Contact Angles ◽  
Char Yield ◽  
Hydroxyethyl Cellulose ◽  
Vapor Permeability ◽  
Significant Activity ◽  
Cellulose Composites

Abstract Sustainable food packaging films were developed using a combination of k-Carrageenan (C), hydroxyl ethyl cellulose (H), silicon dioxide (SiO2), and silver (Ag) nanoparticles. The CH-SiO2/Ag nanocomposites showed promising results, mainly due to their transparency, flexibility, low cost, and environmental friendliness. The structure and uniform morphology of the CH-SiO2/Ag nanocomposites were determined by FT-IR, XRD, and SEM analysis. Barrier properties (water vapor permeability-WVP), thermal properties (T5% loss, char yield), and mechanical properties determined for the CH and CH-SiO2/Ag nanocomposites, which improved by 3.3–1.9 ×10− 9gm/m2 Pas (WVP), 59.1-115.7 oC (T5%), 13.4–29.3 % (char yield), 23.8–41.5 MPa(tensile strength), and 22.3–28.9 (EB), respectively. The contact angles of the CH-SiO2/Ag nanocomposites were in the range of 60.1–76.4. The UV transmittance of the CH composites decreased with the addition of SiO2 and Ag nanoparticles. However, the transparency of the composites was not affected, and it inhibited UVA and UVB rays by the addition of Ag nanoparticles. The viscosity of the CH composites increased with the SiO2 content and decreased with the shear rate. All the composites exhibited shear-thinning behavior. The storage modulus of the prepared composites is higher than the loss modulus in the entire frequency region. Overall, SiO2 and Ag nanoparticles improved the hydrophilic nature of the CH-SiO2/Ag films and showed significant activity against six common food pathogens, Staphylococcus aureus, Bacillus cereus, Listeria monocytogenes, Bacillus subtilis, Salmonella typhi, and Cronobacter sakazakii. The synergistic combination of CH-SiO2/Ag nanocomposite has potential for packaging and other biomedical applications.

scholarly journals Use of antimicrobial packaging systems in the production and storage of meat and meat products

2021 ◽  
Vol 7 (2) ◽  
pp. 150-163
Author(s):  
Yasemin Çelebi Sezer ◽  
Hüseyin Bozkurt
Keyword(s):  
Shelf Life ◽  
Food Packaging ◽  
Antimicrobial Agents ◽  
Meat Products ◽  
Antimicrobial Properties ◽  
Cost Effective ◽  
Processed Meat ◽  
Negative Effects ◽  
Antimicrobial Packaging ◽  
And Storage

Many microbiological, enzymatic, physicochemical, and biochemical changes occur during the production and storage of fresh and processed meat products, which tend to deteriorate more easily by their nature. Nevertheless, consumers mainly prefer cost-effective foods that have a longer shelf life and minimally modified natural properties, can be easily prepared, and in which fewer additives are used. For these reasons, the food packaging industry has turned towards developing new applications with different functions that are not found in traditional packaging methods, such as antimicrobial packaging systems, especially for the protection and improvement of food quality and safety. In this type of packaging, in addition to improving food safety and quality, the shelf life of the product is extended by slowing down the growth rate of microorganisms. Thus, the existing growth of microorganisms during the transportation and storage of the product is also prevented. Therefore, the preservatives taken into the human body with foods are reduced, and the negative effects on health are also avoided. In these systems, the application of antimicrobial food packaging components to the packaging material can be performed by the addition of antimicrobial agents into the polymer, coating polymer surfaces with antimicrobial agents, immobilizing antimicrobial agents on the polymer, and using polymers with antimicrobial properties. In this review, antimicrobial packaging and application methods were generally explained, and innovative packaging systems and their use in meat and meat products were evaluated.

Antimicrobial properties of actively purified secondary metabolites isolated from different marine organisms

2020 ◽  
Vol 21 ◽  
Author(s):  
Nilushi Indika Bamunu Arachchige ◽  
Fazlurrahman Khan ◽  
Young-Mog Kim
Keyword(s):  
Secondary Metabolites ◽  
Pathogenic Bacteria ◽  
Antimicrobial Agents ◽  
Bacterial Species ◽  
Antimicrobial Properties ◽  
Antimicrobial Effect ◽  
Cost Effective ◽  
Resistance Mechanisms ◽  
Marine Organisms ◽  
Antimicrobial Compounds

Background: The treatment of infection caused by pathogenic bacteria becomes one of the serious concerns globally. The failure in the treatment was found due to the exhibition of multiple resistance mechanisms against the antimicrobial agents. Emergence of resistant bacterial species has also been observed due to prolong treatment using conventional antibiotics. To combat these problems, several alternative strategies have been employed using biological and chemically synthesized compounds as antibacterial agents. Marine organisms considered as one of the potential sources for the isolation of bioactive compounds due to the easily available, cost-effective, and eco-friendly. Methods: The online search methodology was adapted for the collection of information related to the antimicrobial properties of marine-derived compounds. These compound has been isolated and purified by different purification techniques, and their structure also characterized. Furthermore, the antibacterial activities have been reported by using broth microdilution as well as disc diffusion assays. Results: The present review paper describes the antimicrobial effect of diverse secondary metabolites which are isolated and purified from the different marine organisms. The structural elucidation of each secondary metabolite has also been done in the present paper, which will help for the in silico designing of the novel and potent antimicrobial compounds. Conclusion: A thorough literature search has been made and summarizes the list of antimicrobial compounds that are isolated from both prokaryotic and eukaryotic marine organisms. The information obtained from the present paper will be helpful for the application of marine compounds as antimicrobial agents against different antibiotic-resistant human pathogenic bacteria.

scholarly journals Silver (I) N-Heterocyclic Carbene Complexes: A Winning and Broad Spectrum of Antimicrobial Properties

2021 ◽  
Vol 22 (5) ◽  
pp. 2497
Author(s):  
Filippo Prencipe ◽  
Anna Zanfardino ◽  
Michela Di Napoli ◽  
Filomena Rossi ◽  
Stefano D’Errico ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Antimicrobial Agents ◽  
Antimicrobial Properties ◽  
Resistance Mechanisms ◽  
Heterocyclic Carbenes ◽  
Significant Activity ◽  
Bacterial Strains ◽  
Development Of Resistance ◽  
Starting Point ◽  
Catalytic Chemistry

The evolution of antibacterial resistance has arisen as the main downside in fighting bacterial infections pushing researchers to develop novel, more potent and multimodal alternative drugs.Silver and its complexes have long been used as antimicrobial agents in medicine due to the lack of silver resistance and the effectiveness at low concentration as well as to their low toxicities compared to the most commonly used antibiotics. N-Heterocyclic Carbenes (NHCs) have been extensively employed to coordinate transition metals mainly for catalytic chemistry. However, more recently, NHC ligands have been applied as carrier molecules for metals in anticancer applications. In the present study we selected from literature two NHC-carbene based on acridinescaffoldand detailed nonclassicalpyrazole derived mono NHC-Ag neutral and bis NHC-Ag cationic complexes. Their inhibitor effect on bacterial strains Gram-negative and positivewas evaluated. Imidazolium NHC silver complex containing the acridine chromophore showed effectiveness at extremely low MIC values. Although pyrazole NHC silver complexes are less active than the acridine NHC-silver, they represent the first example of this class of compounds with antimicrobial properties. Moreover all complexesare not toxic and they show not significant activity againstmammalian cells (Hek lines) after 4 and 24 h. Based on our experimental evidence, we are confident that this promising class of complexes could represent a valuable starting point for developing candidates for the treatment of bacterial infections, delivering great effectiveness and avoiding the development of resistance mechanisms.

scholarly journals Basil Essential Oil: Composition, Antimicrobial Properties, and Microencapsulation to Produce Active Chitosan Films for Food Packaging

Foods ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 121
Author(s):  
Ghita Amor ◽  
Mohammed Sabbah ◽  
Lucia Caputo ◽  
Mohamed Idbella ◽  
Vincenzo De Feo ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Essential Oil ◽  
Shelf Life ◽  
Food Packaging ◽  
Antimicrobial Properties ◽  
Edible Films ◽  
Biological Properties ◽  
Oil Composition ◽  
Packaging System ◽  
Cooked Ham

The essential oil (EO) from basil—Ocimum basilicum—was characterized, microencapsulated by vibration technology, and used to prepare a new type of packaging system designed to extend the food shelf life. The basil essential oil (BEO) chemical composition and antimicrobial activity were analyzed, as well as the morphological and biological properties of the derived BEO microcapsules (BEOMC). Analysis of BEO by gas chromatography demonstrated that the main component was linalool, whereas the study of its antimicrobial activity showed a significant inhibitory effect against all the microorganisms tested, mostly Gram-positive bacteria. Moreover, the prepared BEOMC showed a spheroidal shape and retained the EO antimicrobial activity. Finally, chitosan-based edible films were produced, grafted with BEOMC, and characterized for their physicochemical and biological properties. Since their effective antimicrobial activity was demonstrated, these films were tested as packaging system by wrapping cooked ham samples during 10 days of storage, with the aim of their possible use to extend the shelf life of the product. It was demonstrated that the obtained active film can both control the bacterial growth of the cooked ham and markedly inhibit the pH increase of the packaged food.

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