scholarly journals Hizikia fusiformis: Pharmacological and Nutritional Properties

Foods ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1660
Author(s):  
Maria Dyah Nur Meinita ◽  
Dicky Harwanto ◽  
Jae-Hak Sohn ◽  
Jin-Soo Kim ◽  
Jae-Suk Choi
Keyword(s):  
Brown Seaweed ◽  
Bioactive Compound ◽  
Pharmacological Properties ◽  
Asian Countries ◽  
Online Search ◽  
Nutritional Properties ◽  
Sargassum Fusiforme ◽  
Hizikia Fusiformis ◽  
Number Of Publications ◽  
Meta Analyses

The brown seaweed Hizikia fusiformis (syn. Sargassum fusiforme), commonly known as “Hijiki”, has been utilized in traditional cuisine and medicine in East Asian countries for several centuries. H. fusiformis has attracted much attention owing to its rich nutritional and pharmacological properties. However, there has been no comprehensive review of the nutritional and pharmacological properties of H. fusiformis. The aim of this systematic review was to provide detailed information from the published literature on the nutritional and pharmacological properties of H. fusiformis. A comprehensive online search of the literature was conducted by accessing databases, such as PubMed, SpringerLink, ScienceDirect, and Google Scholar, for published studies on the nutritional and pharmacological properties of H. fusiformis between 2010 and 2021. A total of 916 articles were screened from all the databases using the preferred reporting items for systematic reviews and meta-analyses method. Screening based on the setdown criteria resulted in 59 articles, which were used for this review. In this review, we found that there has been an increase in the number of publications on the pharmacological and nutritional properties of H. fusiformis over the last 10 years. In the last 10 years, studies have focused on the proximate, mineral, polysaccharide, and bioactive compound composition, and pharmacological properties, such as antioxidant, anticancer, antitumor, anti-inflammatory, photoprotective, neuroprotective, antidiabetic, immunomodulatory, osteoprotective, and gastroprotective properties of H. fusiformis extracts. Overall, further studies and strategies are required to develop H. fusiformis as a promising resource for the nutrition and pharmacological industries.

scholarly journals Prevalence of mental disorders in South Asia: an umbrella review of systematic reviews and meta-analyses

2020 ◽  
Author(s):  
Md Mahbub Hossain ◽  
Neetu Purohit ◽  
Abida Sultana ◽  
Ping Ma ◽  
E. Lisako J. McKyer ◽  
...  
Keyword(s):  
Mental Health ◽  
Mental Disorders ◽  
South Asia ◽  
South Asian ◽  
Systematic Reviews ◽  
Mental Health Problems ◽  
Future Research ◽  
Asian Countries ◽  
Umbrella Review ◽  
Meta Analyses

Objectives: Mental disorders are highly prevalent in eight South Asian countries, yet there is a gap of a synthesized overview of the prevalence of mental disorders in this region. This umbrella review aims to summarize the prevalence of mental disorders from systematic reviews and meta-analyses of South Asian studies.Materials and methods: A systematic search of 11 major databases and additional sources was conducted until December 11, 2019. Articles were included if they were systematic reviews or meta-analyses, reported the prevalence of mental disorders, and reported primary studies conducted in South Asian countries only. Results: Among 2591 citations, a total of 23 reviews met all the criteria of this umbrella review. The synthesized findings from those reviews suggest high prevalence rates for mental disorders, including depressive disorders, anxiety disorders, mood disorders, suicidal behavior and self-harm, schizophrenia, substance use disorders, neurodevelopmental disorders, dementia, and other mental health problems. Also, findings suggest a high burden of maternal depression, psychiatric comorbidities in chronic physical illnesses, and various mental disorders among children, elderly adults, refugees, and other vulnerable populations. Most studies were from India whereas evidence from Afghanistan, Bhutan, and Maldives was limited.Conclusion: The findings of this review are constrained with heterogeneity in prevalence estimations, methodologies, sampling issues, and limitations in the existing literature, which should be addressed in future research. The evidence synthesized in this review provides national and regional overview of the prevalence of mental disorders, which may inform better policymaking and practice advancing mental health in South Asia.

scholarly journals Fucosterol of Marine Macroalgae: Bioactivity, Safety and Toxicity on Organism

Marine Drugs ◽  
2021 ◽  
Vol 19 (10) ◽  
pp. 545
Author(s):  
Maria Dyah Nur Meinita ◽  
Dicky Harwanto ◽  
Gabriel Tirtawijaya ◽  
Bertoka Fajar Surya Perwira Negara ◽  
Jae-Hak Sohn ◽  
...  
Keyword(s):  
Cell Lines ◽  
Marine Algae ◽  
Animal Cell ◽  
Biological Activities ◽  
Clinical Stage ◽  
Bioactive Compound ◽  
Marine Macroalgae ◽  
Pharmaceutical Industries ◽  
Safety And Toxicity ◽  
Meta Analyses

Fucosterol (24-ethylidene cholesterol) is a bioactive compound belonging to the sterol group that can be isolated from marine algae. Fucosterol of marine algae exhibits various biological activities including anti-osteoarthritic, anticancer, anti-inflammatory, anti-photoaging, immunomodulatory, hepatoprotective, anti-neurological, antioxidant, algicidal, anti-obesity, and antimicrobial. Numerous studies on fucosterol, mainly focusing on the quantification and characterization of the chemical structure, bioactivities, and health benefits of fucosterol, have been published. However, there is no comprehensive review on safety and toxicity levels of fucosterol of marine algae. This review aims to discuss the bioactivities, safety, and toxicity of fucosterol comprehensively, which is important for the application and development of fucosterol as a bioactive compound in nutraceutical and pharmaceutical industries. We used four online databases to search for literature on fucosterol published between 2002 and 2020. We identified, screened, selected, and analyzed the literature using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses method and identified 43 studies for review. Despite the potential applications of fucosterol, we identified the need to fill certain related research gaps. Fucosterol exhibited low toxicity in animal cell lines, human cell lines, and animals. However, studies on the safety and toxicity of fucosterol at the clinical stage, which are required before fucosterol is developed for the industry, are lacking.

118 The Use of Meta-analysis in Companion Animal Research

2021 ◽  
Vol 99 (Supplement_3) ◽  
pp. 62-62
Author(s):  
Emma N Bermingham
Keyword(s):  
Body Size ◽  
Statistical Analysis ◽  
Meta Analysis ◽  
Energy Requirements ◽  
Specific Question ◽  
Research Findings ◽  
Adult Cat ◽  
Number Of Publications ◽  
Meta Analyses ◽  
The Three Rs

Abstract In a world of the “Three Rs” (replace, reduce and refine), combined with more research published via open access research journals, there is increasing interest in the statistical analysis of existing literature. Meta-analysis – the combination of multiple studies, can be used to get better oversight into a specific question of interest. Additionally, it can be used to identify gaps in knowledge. For example, while there are a number of publications investigating energy requirements in adult cat and dog, few studies assess older animals. Similarly, in the dog, there is a lack of literature around dogs at the extremes of body size (i.e. giant and toy breeds). Herein, we describe several published examples that have been used to determine energy requirements of cats and dogs, and more recently, the impacts of diet on the microbiome of the cat and dog. This includes the use of Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines, research findings and general findings related to research design and quality.

Study of the potential use of the invasive marine algae Undaria pinnatifida in the preliminary development of a functional textile

2020 ◽  
pp. 152808372096706
Author(s):  
Maria Alejandra Martinez ◽  
Maria Eugenia Becherucci
Keyword(s):  
Nutritive Value ◽  
Undaria Pinnatifida ◽  
Brown Seaweed ◽  
Asian Countries ◽  
Chemical Substances ◽  
Technical Textiles ◽  
Body Care ◽  
Near Future ◽  
Positive Effect ◽  
Potential Use

Seaweeds are considered to be an important source of relevant chemical substances or bioactive compounds of great usefulness in the medical, cosmetic, pharmaceutical or food industry. Recently, some seaweed had been used to produce or incorporate in fibers in order to manufacture technical textiles in which functional ingredient of the seaweed are exploited in the health and body care area. The brown seaweed Undaria pinnatifida (Undaria) has an important nutritive value being consumed as food in several Asian countries. As well Undaria is required in cosmetic or dermatology medicine given the presence of other bioactive chemical substances known as phycocolloids. The objective of this study was to explore the potential use of Undaria in a preliminary development of a functional textile. A soft bilaminate textile with a high crease recovery and an efficient release of mucilage, was achieved using a fine dust (particle of <0.26 mm) of Undaria between two layers of nonwoven. The best combination of the two layers of nonwoven was laminate and fine spundbond. The extract of Undaria used in our experimentation had minerals and vitamins with positive effect to the human skin, besides it is no irritant when applied to healthy or abraded skin. Further research focused in the incorporation of this alga in nonwoven fibers is required. We expect to obtain a textile with a dermatologic use in the near future; so as to turn Undaria into a resource susceptible to exploitation given the specie is considered a worldwide plague.

Transparency of reporting in CALL meta-analyses between 2003 and 2015

ReCALL ◽  
2017 ◽  
Vol 30 (3) ◽  
pp. 253-277 ◽  
Author(s):  
Huifen Lin ◽  
Tsuiping Chen ◽  
Hsien-Chin Liou
Keyword(s):  
Language Learning ◽  
Meta Analysis ◽  
Empirical Studies ◽  
Research Synthesis ◽  
Computer Assisted ◽  
Computer Assisted Language Learning ◽  
Conducting Research ◽  
Number Of Publications ◽  
Meta Analyses ◽  
Research Domain

AbstractSince its introduction by Glass in the 1970s, meta-analysis has become a widely accepted and the most preferred approach to conducting research synthesis. Overcoming the weaknesses commonly associated with traditional narrative review and vote counting, meta-analysis is a statistical method of systematically aggregating and analyzing empirical studies by following well-established procedures. The findings of a meta-analysis, when appropriately conducted, are able to inform important policy decisions and provide practical pedagogical suggestions. With the growing number of publications employing meta-analysis across a wide variety of disciplines, it has received criticism due to its inconsistent findings derived from multiple meta-analyses in the same research domain. These inconsistencies have arisen partly due to the alternatives available to meta-analysts in each major meta-analytic procedure. Researchers have therefore recommended transparent reporting on the decision-making for every essential judgment call so that the results across multiple meta-analyses become replicable, consistent, and interpretable. This research explored the degree to which meta-analyses in the computer-assisted language learning (CALL) discipline transparently reported their decisions in every critical step. To achieve this aim, we retrieved 15 eligible meta-analyses in CALL published between 2003 and 2015. Features of these meta-analyses were extracted based on a codebook modified from Cooper (2003) and Aytug, Rothstein, Zhou and Kern (2012). A transparency score of reporting was then calculated to examine the degree to which these meta-analyses are compliant with the norms of reporting as recommended in the literature. We then discuss the strengths and weaknesses of the methodologies and provide suggestions for conducting quality meta-analyses in this domain.

scholarly journals Characterization of Polysaccharides Extracted from Sargassum fusiforme and Its Effective Prevention of Contrast-Induced Nephropathy via Enhancing Antioxidant Capacity

2019 ◽  
Vol 2019 ◽  
pp. 1-8 ◽  
Author(s):  
Min Dai ◽  
Ying-Ling Zhou ◽  
Tao Jiang ◽  
Cai-Dong Luo ◽  
Hu Wang ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cold Water ◽  
Radical Scavenging ◽  
Brown Seaweed ◽  
Hot Water ◽  
Molar Ratio ◽  
Sulfated Polysaccharides ◽  
Contrast Induced Nephropathy ◽  
Effective Prevention ◽  
Sargassum Fusiforme

Contrast-induced nephropathy (CIN) is a common complication in patients with coronary arteriography, and oxidative stress is involved in the CIN pathogenesis. Sargassum fusiforme (SF) is a brown seaweed with medicinal value, and its polysaccharides have good antioxidant activity. In this study, the crude polysaccharides (cSFP-C) were extracted by cold water, precipitated by ethanol, purified by CaCl2, and detected with high contents of sulfate radical and fucose. cSFP-C is composed of glucose, glucuronic acid, xylose, rhamnose, mannose, galactose, and fucose with a molar ratio of 1.0 : 0.4 : 5.6 : 1.2 : 1.7 : 12.3 : 56.1. The cSFP-C has the typical absorption of polysaccharides. Antioxidation assays in vitro showed that cSFP-C exhibited superoxide radical scavenging activity which was better than the hot water-extracted crude polysaccharides (cSFP-H). 20 rats were divided into 4 groups (n=5): sham group; CIN group; CIN+cSFP-C group, and cSFP-C group. The CIN+cSFP-C group and cSFP-C group were pretreated intragastrically with cSFP-C at a dose of 9.45 g/kg twice daily for 5 consecutive days. Then, the CIN group and CIN+cSFP-C group were given indomethacin to develop CIN. The in vivo results showed that cSFP-C could decrease blood creatinine and urea nitrogen, inhibiting pathological injury in the renal tissues. The MDA content of renal tissues was decreased, while the activity of SOD was increased. The crude sulfated polysaccharides extracted from S. fusiforme have a renoprotective effect on oxidative stress to alleviate the kidney injury in CIN rats.

scholarly journals UJI DAYA HAMBAT EKSTRAK RUMPUT LAUT GRACILARIA SP TERHADAP PERTUMBUHAN BAKTERI STAPHYLOCOCCUS AUREUS

e-GIGI ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Torar S. S. Toy ◽  
Benedictus S. Lampus ◽  
Bernat S. P. Hutagalung
Keyword(s):  
Staphylococcus Aureus ◽  
Experimental Design ◽  
Brown Seaweed ◽  
Control Design ◽  
Bioactive Compound ◽  
Inhibition Zone ◽  
Gracilaria Verrucosa ◽  
Seaweed Extract ◽  
Rotary Evaporator ◽  
Study Results

Abstract: Infection usually caused by microorganism such as bacterial. One example of infection is abscess which caused by Staphylococcus aureus. Staphylococcus aureus is a pathogenic bacterial in mouth. Seaweed is a part of sea plants. Nowadays, seaweed has been used as material of agar-agar, alginate, and even medicine. Indonesia has good potential to develop and use its richness at the sea. One of species that has been cultivated is Gracilaria verrucosa or known with local name “bulung rambu” (Bali) or “sango-sango” (Sulawesi). The characteristics of Gracilaria verrucosa is thallus silindris, slick, and has yellowish-brown or yellowish-green. Green, red, or brown seaweed is a potential source of bioactive compound that useful for pharmacy industry improvement like antibacterial, antivirus, antifungal, and cytostatic. This study purpose was to find out if seaweed extract (Gracilaria sp.) can inhibit growth of Staphylococcus aureus. This study was an experimental laboratory with true experimental design and posttest only control design. study subject are seaweed extract Gracilaria sp. that dissolved with 95% ethanol which evaporated in oven. Inhibition zone of Gracilaria sp. extract evaporated in the oven at each repeated were 2.5mm, 3.5mm, 3mm. Inhibition zone created from Gracilaria sp. extract that evaporated with vacuum rotary evaporator in each repeated were 2mm, 2mm, and 2.5mm. Study results showed that seaweed extract (Gracilaria sp.) didn’t have exhibition zone against Staphylococcus aureus.Keywords: inhibition test, seaweed (gracilaria sp), staphylococcus aureus.Abstrak: Penyakit infeksi yang biasanya disebabkan oleh mikroorganisme yaitu bakteri. Salah satu contoh penyakit infeksi tersebut yaitu abses yang disebabkan oleh bakteri Staphylococcus aureus. Staphylococcus aureus adalah patogen utama dalam rongga mulut. Rumput laut merupakan bagian dari tumbuhan laut perairan. Saat ini rumput laut telah dimanfaatkan sebagai bahan baku industri agar-agar, dan alginat bahkan obat-obatan. Indonesia mempunyai potensi yang baik untuk mengembangkan dan memanfaatkan kekayaan lautnya. Salah satu jenis yang sudah banyak dibudidayakan adalah Gracilaria verrucosa atau dikenal dengan nama daerah bulung rambu (bali) atau sango-sango (sulawesi). Ciri-ciri dari Gracilaria verrucosa, yaitu thallus silindris, licin, dan berwarna kuning-coklat atau kuning-hijau.Rumput laut hijau, merah ataupun coklat merupakan sumber potensial senyawa bioaktif yang sangat bermanfaat bagi pengembangan industri farmasi seperti sebagai antibakteri, antivirus, antijamur dan sitotastik. Penelitian ini bertujuan untuk mengetahui apakah ekstrak rumput laut (Gracilaria sp.) dapat menghambat pertumbuhan bakteri Staphylococcus aureus. Penelitian ini merupakan penelitian eksperimental laboratorium, menggunakan rancangan eksperimental murni (true experimental design) dengan rancangan penelitian posttest only control design. Subjek dari penelitian ini ialah ekstrak rumput laut Gracilaria sp. yang dilarutkan dengan etanol 95% yang dievaporasi menggunakan rotary vacuum evaporator dan dipanaskan dalam oven. zona hambat dari ekstrak Gracilaria sp. yang dievaporasi dengan oven pada masing-masing pengulangan ialah 2,5 mm, 3,5 mm, 3 mm. Demikian juga zona hambat yang terbentuk dari ekstrak Gracilaria sp. yang dievaporasi dengan vacuum rotary evaporator pada masing-masing pengulangan ialah 2 mm, 2 mm, dan 2,5 mm. Hasil penelitian menunjukkan bahwa ekstrak rumput laut (Gracilaria sp.) tidak memiliki daya hambat terhadap bakteri Staphylococcus aureus.Kata kunci: uji daya hambat, rumput laut (gracilaria sp.), staphylococcus aureus.

scholarly journals Bioactive Compounds of Seaweed Sargassum plagyophyllum and Eucheuma cottonii as Lightening Raw Materials

2017 ◽  
Vol 20 (3) ◽  
pp. 632 ◽  
Author(s):  
Maretty Twentyna Dolorosa ◽  
N. Nurjanah ◽  
Sri Purwaningsih ◽  
Effionora Anwar ◽  
Taufik Hidayat
Keyword(s):  
Heavy Metal ◽  
Vitamin C ◽  
Moisture Content ◽  
Bioactive Compounds ◽  
Raw Materials ◽  
Brown Seaweed ◽  
Chemical Characterization ◽  
Bioactive Compound ◽  
Plate Count ◽  
Phytochemical Compounds

Seaweed is main commodity with abundant amount of Indonesian waters. Seaweed contains naturally bioactive compounds that acts as antioxidant and tyrosinase inhibitor which inhibit melanin formation and the latest approach used to skin lightening. The aim of this research were to determine chemical characterization such as heavy metal, secondary metabolite (phytochemical compounds), moisture, vitamin C and E, antioxidant activity and total plate count (TPC) on dry simplisia and slurry of S. plagyophyllum and E. cottonii. Total microbe of S. plagyophyllum amounted 2,3×102 colony⁄g with moisture content 16,71% and E. cottonii amounted 2,2×103 colony⁄g with moisture content 19,79%. Brown seaweed, S. plagyophyllum, did not contain dangerous heavy metal. Vitamin C value in both spesies of seaweed were 212,95 mg/kg for<br />S. plagyophyllum and 15,95 mg/kg for E. cottonii. Vitamin E of S. plagyophyllum amounted 363,86 mg/kg and 0,23 mg/kg for E. cottonii. IC50  value of S. plagyophyllum was 109 ppm and 130,62 ppm for E. cottonii. S. plagyophyllum slurry contain bioactive compound such as alkaloids, steroids, flavonoids, saponins and tannins. E. cottonii slurry contain bioactive compound alkaloids and terpenoids.<br /><br />

scholarly journals Momordica cochinchinensis Spreng (Gac fruit): An abundant source of nutrient, phytochemicals and its pharmacological activities

2020 ◽  
pp. 1844-1854
Author(s):  
Priscilla Jayanthi Thavamany ◽  
Hong Lim Chew ◽  
Sreeramanan S. ◽  
Bee Lynn Chew ◽  
Ming-Thong Ong
Keyword(s):  
Nutritive Value ◽  
Biological Activities ◽  
Folk Medicine ◽  
Asian Countries ◽  
Anticancer Activities ◽  
Nutritional Properties ◽  
Pharmacological Activities ◽  
Phytochemical Composition ◽  
Momordica Cochinchinensis ◽  
Β Carotene

Gac fruit (Momordica cochinchinensis Spreng) is an exploitable perennial dioecious fruit found commonly in Southeast Asian countries (SA). Gac fruit has been traditionally used in folk medicine due to its high medicinal and nutritive value. Generally, the aril of the fruit is used as a red colourant for cuisines and supplement for healthier vision. Gac fruit is highly rich in lycopene and β- carotene, fatty acids, vitamin E, polyphenols like phenolic acids, flavonoids and trypsin inhibitors. These compounds are linked with many important bioactivities such as provitamin A, antioxidant, antimicrobial, antiulcer and anticancer activities. This paper reviews the findings on nutritional properties, phytochemical composition and the biological activities of Gac fruit. The review has also briefly discussed the suitable conditions for the storage and utilisation of the fruit in food, beverage, nutraceutical, pharmaceutical and cosmeceutical industries

scholarly journals Anterior Cruciate Ligament Publications in Asia in 10 Years: A Systematic Review

2020 ◽  
Vol 11 (4) ◽  
Author(s):  
Sholahuddin Rhatomy ◽  
Riky Setyawan ◽  
Anggaditya Putra ◽  
Dwikora Novembri Utomo
Keyword(s):  
Anterior Cruciate Ligament ◽  
Clinical Research ◽  
Cruciate Ligament ◽  
Cochrane Library ◽  
Asian Countries ◽  
High Impact Journal ◽  
Study Results ◽  
Anterior Cruciate ◽  
Number Of Publications ◽  
Study Type

Background: There have been numerous articles about the anterior cruciate ligament (ACL). But there has been no specific article describing ACL in Asian countries. Objectives: This study aims to provide the publications about ACL in Asian countries in the last 10 years. Methods: We searched English full text with keywords “ACL” OR “Anterior Cruciate Ligament” AND “injury” OR “tear” OR “rupture” that were published from January 1st 2010 to December 31st 2019 on PubMed, EMBASE, and Cochrane Library. We included articles with at least one author affiliation in an Asian country. We analyzed the number of published articles per year, top 10 journals with the highest number of publications, top 5 authors with the highest number of published articles in the first order author, top 10 countries with the highest number of published articles, and the type of study. Results: A total of 821 articles were analyzed, of which 821 were included. Analysis of the number of articles by year revealed that 2019 was the highest number of published articles (n = 150; 18.3%). Study type analysis revealed that clinical research (n = 398; 48.5%) was the most frequent study type. Cohort studies were the most frequent type of clinical research (n = 169; 42.5%). The journal of knee surgery, sports traumatology, arthroscopy (KSSTA) had the highest number of publications in general (n = 108; 13.2%). Jung Ho Noh (n = 8) was the top author with the highest number of published articles in the first author order, and Ryosuke Kuroda (n = 24) was the top author with the highest number of published articles. Japan was the top country with the highest number of published articles (n = 203; 24.7%). Most of the studies (n = 395; 48.1%) were published in high index journals with an impact factor > 1.0. Conclusions: There has been an increase in the ACL publications among Asian authors over the past 10 years with the high impact journal publishers. This article demonstrates the increased interest in the ACL topic and could be used as a basis for future studies.

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