scholarly journals Genomic Regions Associated with Variation in Pigmentation Loss in Saddle Tan Beagles

Genes ◽  
2021 ◽  
Vol 12 (2) ◽  
pp. 316
Author(s):  
Mia E. Nord ◽  
Per Jensen

Loss of pigmentation is a hallmark of domestication, and dogs offer a unique model for understanding the genetics of fur coloration. The aim of this study was to use dense genetic mapping to map loci underlying variations in color and whiteness in a population of laboratory beagles. A total of 190 beagles with well-defined pedigrees were phenotyped for the amount of white color in six different body parts, including the saddle. All individuals were genotyped on 85,172 informative and valid SNP-markers and the genome-wide associations for the amount of white in each body part were determined. There was a large variation in the amount of white on different parts of the body, and the whiteness was highly correlated within individuals, except for saddle color which was only moderately correlated with overall whiteness. The GWAS showed significant associations with two loci, one on chromosome 5, containing the MC1R gene, and one on chromosome 20, containing the MITF gene. Our results suggest that the variation in loss of pigmentation is largely a function of regulatory variation related to these genes.

Parasitology ◽  
2012 ◽  
Vol 139 (13) ◽  
pp. 1739-1748 ◽  
Author(s):  
SHAI PILOSOF ◽  
MARCELA LARESCHI ◽  
BORIS R. KRASNOV

SUMMARYWe studied the distribution of ectoparasite species (an ixodid tick, a chigger mite, 7 mesostigmate mites, 5 fleas and 3 lice) on bodies of 5 species of rodent hosts from the marshlands in Argentina to establish whether arthropod ectoparasites are segregated across body parts of the same host individual. We asked (a) whether an individual ectoparasite species prefers certain parts of the body of its host and, if yes, whether these preferences overlap among ectoparasite species; (b) whether ectoparasite species composition differs among different parts of a host's body; and (c) whether co-occurrences of ectoparasite species within pre-defined body parts of a host are non-random and, if yes, whether ectoparasites co-occur in the same body part of a host either less or more often than expected by chance. It was found that, in general, ectoparasite species were not segregated across body parts of a host. Although some ectoparasites preferred certain body parts, these preferences were similar among ectoparasites belonging to different species and/or higher taxa resulting in similarity among host body parts in ectoparasite species composition. In addition, ectoparasite species demonstrated a tendency to co-occur on the same body parts of a host and not to be segregated among them. It was concluded that the distribution of ectoparasites on the body of a small mammalian host is driven mainly by their interaction with the host rather than by distinct preferences or interactions among ectoparasite species.


Author(s):  
Rajendra Pai N. ◽  
U. Govindaraju

Ayurveda in its principle has given importance to individualistic approach rather than generalize. Application of this examination can be clearly seem like even though two patients suffering from same disease, the treatment modality may change depending upon the results of Dashvidha Pariksha. Prakruti and Pramana both used in Dashvidha Pariksha. Both determine the health of the individual and Bala (strength) of Rogi (Patient). Ayurveda followed Swa-angula Pramana as the unit of measurement for measuring the different parts of the body which is prime step assessing patient before treatment. Sushruta and Charaka had stated different Angula Pramana of each Pratyanga (body parts). Specificity is the characteristic property of Swa-angula Pramana. This can be applicable in present era for example artificial limbs. A scientific research includes collection, compilation, analysis and lastly scrutiny of entire findings to arrive at a conclusion. Study of Pramana and its relation with Prakruti was conducted in 1000 volunteers using Prakruti Parkishan proforma with an objective of evaluation of Anguli Pramana in various Prakriti. It was observed co-relating Pramana in each Prakruti and Granthokta Pramana that there is no vast difference in measurement of head, upper limb and lower limb. The observational study shows closer relation of features with classical texts.


2010 ◽  
Vol 16 (4) ◽  
pp. 112-121 ◽  
Author(s):  
Brennen W. Mills ◽  
Owen B. J. Carter ◽  
Robert J. Donovan

The objective of this case study was to experimentally manipulate the impact on arousal and recall of two characteristics frequently occurring in gruesome depictions of body parts in smoking cessation advertisements: the presence or absence of an external physical insult to the body part depicted; whether or not the image contains a clear figure/ground demarcation. Three hundred participants (46% male, 54% female; mean age 27.3 years, SD = 11.4) participated in a two-stage online study wherein they viewed and responded to a series of gruesome 4-s video images. Seventy-two video clips were created to provide a sample of images across the two conditions: physical insult versus no insult and clear figure/ground demarcation versus merged or no clear figure/ground demarcation. In stage one, participants viewed a randomly ordered series of 36 video clips and rated how “confronting” they considered each to be. Seven days later (stage two), to test recall of each video image, participants viewed all 72 clips and were asked to identify those they had seen previously. Images containing a physical insult were consistently rated more confronting and were remembered more accurately than images with no physical insult. Images with a clear figure/ground demarcation were rated as no more confronting but were consistently recalled with greater accuracy than those with unclear figure/ground demarcation. Makers of gruesome health warning television advertisements should incorporate some form of physical insult and use a clear figure/ground demarcation to maximize image recall and subsequent potential advertising effectiveness.


2013 ◽  
Vol 5 (3) ◽  
pp. 545-553 ◽  
Author(s):  
M. G. Sarower ◽  
S. Bilkis ◽  
M. A. Rauf ◽  
M. Khanom ◽  
M. S. Islam

The biochemical composition (proteins, lipid, ash and moisture) of different parts of the body (gill, meat, egg) of fattened and natural mud crab Scylla serrata was determined. Twenty four samples of S. serrata (12 from wild & 12 from fattening farm) of different sizes and sexes (half of the sample is male) were used in this study. The mean protein and lipid contents are significantly (p<0.05) higher in fattened crabs than natural in natural crabs regardless of size and sexes.  Moisture and ash were higher in natural crab than in fattened ones. The highest and lowest moisture content was noticed in gills and eggs in both natural and fattened crabs. Protein and lipid contents were comparatively higher in eggs than in other body parts. Female crabs contained high protein and lipid than males in both natural and fattened crabs.  From the results of this study it may considered that fattened crab might be comparatively superior to natural crabs as they appear to provide higher levels of protein and fat  for human nutrition. Keywords: Biochemical composition; Natural and Fattened mud crab; Scylla serrata   © 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. doi: http://dx.doi.org/10.3329/jsr.v5i3.14082 J. Sci. Res. 5 (3), 545-553 (2013)


2018 ◽  
Vol 7 (3.24) ◽  
pp. 44
Author(s):  
Norlizaa Mohamad ◽  
Jafri Mohd Rohani ◽  
Ismail Abdul Rahman ◽  
Anis Amira Mat Zuki

Prolonged standing is one of the common activities in electronic industry as the task requirement. Prolonged standing can cause discomfort on the body of the workers and can lead to injury and occupational disease. The purpose of this study is to investigate standing workers perception on the fatigue and the discomfort on their respective body region for 12 hours working time. The subjects are the 80 workers with a good health condition and at least 6 months tenure. The subject data are collected via questionnaires and Likert scale to define the discomfort, pain, and fatigue. The workers were interviewed regarding their job and perceived fatigue discomfort. The results show the domination of the lower body region with the higher mean at the lower back, legs, and foot ankle. No statistically significant differences were found between the job tenure and body part discomfort pain and fatigue. There is a significant relation between gender and discomfort pain on legs and foot ankle. The result also shows a strong relation between age and the discomfort body parts of thigh and foot ankle. The perceptions of the workers towards discomfort pain and fatigue cause by prolonged standing during performing the task. The results from this study will provide a view for industrial consultants or ergonomist with evidence to support for ergonomic interventions for prolonged standing activity such as job rotation and work-rest schedule. 


2012 ◽  
Vol 16 (3) ◽  
pp. 319-335
Author(s):  
Bistoon Abasi ◽  
Amer Gheitury

Human body as a universal possession of human beings constitutes an interesting domain where questions regarding semantic categorisations might be sought crosslinguistically. In the following, we will attempt to describe the terms used to refer to the body in Hawrami, an Iranian language spoken in Paveh, a small township in the western province of Kermanshah near Iraqi borders. Due to the scarcity of written material, the inventory of 202 terms referring to external and internal body parts were obtained through a field work, which took a long time, and techniques, such as the “colouring task”, observation and recording the terms as used in ordinary conversations and informal interviews with native speakers. The semantic properties of the terms and the way they are related in a partonymy or locative relationship were also investigated. As far as universals of body part terms are concerned, while conforming to ‘depth principle’ concerning the number of levels each partonomy may consist of, Hawrami violates an important feature of this principle by not allowing transitive relations between different levels of partonomic hierarchies. In addition, Hawrami lacks a term for labelling the ‘whole’.


2002 ◽  
Vol 10 (1-2) ◽  
pp. 341-367 ◽  
Author(s):  
Ning Yu

This study presents a semantic analysis of how emotions and emotional experiences are described in Chinese. It focuses on conventionalized expressions in Chinese, namely compounds and idioms, which contain body-part terms. The body-part terms are divided into two classes: those denoting external body parts and those denoting internal body parts or organs. It is found that, with a few exceptions, the expressions involving external body parts are originally metonymic, describing emotions in terms of their externally observable bodily events and processes. However, once conventionalized, these expressions are also used metaphorically regardless of emotional symptoms or gestures. The expressions involving internal organs evoke imaginary bodily images that are primarily metaphorical. It is found that the metaphors, though imaginary in nature, are not really all arbitrary. They seem to have a bodily or psychological basis, although they are inevitably influenced by cultural models.


1970 ◽  
Vol 176 (1044) ◽  
pp. 291-293

It is generally assumed that in multicellular organisms the diversity of the different cell types is the result of different gene activity which becomes manifest in the course of development. This theoretical concept of cell differentiation was developed on the basis of results obtained from a relatively small number of suitable experimental systems. One of them comprises the imaginal disks of the fruitfly Drosophila melanogaster . Imaginal disks are larval primordia in holometabolic insects such as flies and mosquitoes, and consist of densely packed populations of morphologically uniform cells. They give rise to defined structures of the adult body (mainly integument), thus replacing parts of the larva which are almost completely histolysed during metamorphosis. The prospective fate of the various imaginal disks can be tested, for example, by transplantation experiments. Individual disks are removed from larvae of a genetically marked strain and transplanted into the body cavity of another larva with which the transplants undergo metamorphosis. The metamorphosed derivatives of the disks are then found in the abdomen of the fly and can be microscopically identified on the basis of the morphology of bristles, hairs and other structural features of the integument. The same method is applied for examination of the developmental performance of disk fragments. From the results of such experiments the following conclusions are drawn: (1) Individual disks of fully grown larvae, that is larvae which are ready to pupate, are determined (programmed) for exactly defined body parts of the adult organism. (2) The individual subregions of such a body part can be localized precisely within a disk. Based on these facts fate maps (anlage plans) can be worked out. (3) From experiments in which different genetically marked disks are intermingled and then transplanted into larvae it is concluded that even single cells are determined for structures of a specific body region.


2021 ◽  
Vol 32 (Issue 1) ◽  
pp. 25-33
Author(s):  
M. Ruiz ◽  
E.A. Rossi ◽  
N.C. Bonamico ◽  
M.G. Balzarini

Maize (Zea Mays L.) production has been greatly benefited from the improvement of inbred lines in regard to the resistance to diseases. However, the absence of resistant genotypes to bacteriosis is remarkable. The aim of the study was to identify genomic regions for resistance to Mal de Río Cuarto (MRC) and to bacterial disease (BD) in a diverse maize germplasm evaluated in the Argentinian region where MRC virus is endemic. A maize diverse population was assessed for both diseases during the 2019-2020 crop season. Incidence and severity of MRC and BD were estimated for each line and a genome wide association study (GWAS) was conducted with 78,376 SNP markers. A multi-trait mixed linear model was used for simultaneous evaluation of resistance to MRC and BD in the scored lines. The germplasm showed high genetic variability for both MRC and BD resistance. No significant genetic correlation was observed between the response to both diseases. Promising genomic regions for resistance to MRC and BD were identified and will be confirmed in further trials. Key words: maize disease; genome wide association study; SNP; multi-trait model


2021 ◽  
Vol 32 (Issue 1) ◽  
pp. 25-33
Author(s):  
M. Ruiz ◽  
E.A. Ross ◽  
N.C. Bonamico ◽  
M.G. Balzarini

Maize (Zea Mays L.) production has been greatly benefited from the improvement of inbred lines in regard to the resistance to diseases. However, the absence of resistant genotypes to bacteriosis is remarkable. The aim of the study was to identify genomic regions for resistance to Mal de Río Cuarto (MRC) and to bacterial disease (BD) in a diverse maize germplasm evaluated in the Argentinian region where MRC virus is endemic. A maize diverse population was assessed for both diseases during the 2019-2020 crop season. Incidence and severity of MRC and BD were estimated for each line and a genome wide association study (GWAS) was conducted with 78,376 SNP markers. A multi-trait mixed linear model was used for simultaneous evaluation of resistance to MRC and BD in the scored lines. The germplasm showed high genetic variability for both MRC and BD resistance. No significant genetic correlation was observed between the response to both diseases. Promising genomic regions for resistance to MRC and BD were identified and will be confirmed in further trials. Key words: maize disease; genome wide association study; SNP; multi-trait model


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