scholarly journals Unveiling Associations of COVID-19 Vaccine Acceptance, Hesitancy, and Resistance: A Cross-Sectional Community-Based Adult Survey

Author(s):  
Carmina Castellano-Tejedor ◽  
María Torres-Serrano ◽  
Andrés Cencerrado

COVID-19 vaccines are essential to limit and eliminate the infectious disease. This research aims to identify strong vaccination resistance profiles and/or hesitation considering health, psychosocial, and COVID-related variables. A cross-sectional online survey (N = 300) was conducted in the context of strict COVID-related gathering and mobility restrictions (January–March 2021). Data collected were vaccine acceptance, hesitancy and resistance rates, general psychosocial status, and preventive practices and beliefs regarding COVID-19 and its vaccination, among other factors. Logistic regression was applied to a real-world data set and a significant model (χ2 (7, N = 278) = 124.548, p < 0.001) explaining 51.3% (R2 Nagelkerke) of attitudes towards vaccination was obtained, including the following predictors for acceptance: to have greater confidence in the COVID vaccine security (OR = 0.599) and effectiveness (OR = 0.683), older age (OR = 0.952), to be a healthcare professional (OR = 0.363), to have vulnerable individuals in charge (OR = 0.330), and sustain the belief that the vaccine will end the pandemic situation (OR = 0.346) or not being sure but give some credence to that belief (OR = 0.414). Findings could help understand the rate and determinants of COVID-19 vaccine resistance/hesitancy among a Spanish population sample and facilitate multifaceted interventions to enhance vaccine acceptance.

Vaccine ◽  
2016 ◽  
Vol 34 (32) ◽  
pp. 3670-3675 ◽  
Author(s):  
Harapan Harapan ◽  
Samsul Anwar ◽  
Abdul Malik Setiawan ◽  
R. Tedjo Sasmono

PLoS ONE ◽  
2021 ◽  
Vol 16 (10) ◽  
pp. e0257437
Author(s):  
Hasheemah Afaneh ◽  
Susanne Straif-Bourgeois ◽  
Evrim Oral ◽  
Ashley Wennerstrom ◽  
Olivia Sugarman ◽  
...  

Introduction This article presents the Louisiana Hepatitis C Elimination Program’s evaluation protocol underway at the Louisiana State University Health Sciences Center–New Orleans. With the availability of direct-acting antiviral (DAA) agents, the elimination of Hepatitis C (HCV) has become a possibility. The HCV Elimination Program was initiated by the Louisiana Department of Health (LDH) Office of Public Health (OPH), LDH Bureau of Health Services Financing (Medicaid), and the Louisiana Department of Public Safety and Corrections (DPSC) to provide HCV treatment through an innovative pricing arrangement with Asegua Therapeutics, whereby a fixed cost is set for a supply of treatment over five years. Materials and methods A cross-sectional study design will be used. Data will be gathered from two sources: 1) an online survey administered via REDCap to a sample of Medicaid members who are receiving HCV treatment, and 2) a de-identified data set that includes both Medicaid claims data and OPH surveillance data procured via a Data Use Agreement between LSUHSC-NO and Louisiana Medicaid. Discussion The evaluation will contribute to an understanding of the scope and reach of this innovative treatment model, and as a result, an understanding of areas for improvement. Further, this evaluation may provide insight for other states considering similar contracting mechanisms and programs.


2020 ◽  
Author(s):  
Ashley E. Kim ◽  
Elisabeth Brandstetter ◽  
Naomi Wilcox ◽  
Jessica Heimonen ◽  
Chelsey Graham ◽  
...  

AbstractIntroductionWhile influenza and other respiratory pathogens cause significant morbidity and mortality, the community-based burden of these infections remains incompletely understood. The development of novel methods to detect respiratory infections is essential for mitigating epidemics and developing pandemic-preparedness infrastructure.MethodsFrom October 2019 to March 2020, we conducted a home-based cross-sectional study in the greater Seattle area, utilizing electronic consent and data collection instruments. Participants received nasal swab collection kits via rapid delivery within 24 hours of self-reporting respiratory symptoms. Samples were returned to the laboratory and were screened for 26 respiratory pathogens and a human marker. Participant data were recorded via online survey at the time of sample collection and one week later.ResultsOf the 4,572 consented participants, 4,359 (95.3%) received a home swab kit, and 3,648 (83.7%) returned a nasal specimen for respiratory pathogen screening. The 3,638 testable samples had a mean RNase P CRT value of 19.0 (SD: 3.4) and 1,232 (33.9%) samples had positive results for one or more pathogens, including 645 (17.7%) influenza-positive specimens. Among the testable samples, the median time between shipment of the home swab kit and completion of laboratory testing was 8 days [IQR: 7.0-14.0].DiscussionHome-based surveillance using online participant enrollment and specimen self-collection is a feasible method for community-level monitoring of influenza and other respiratory pathogens, which can readily be adapted for use during pandemics.


2021 ◽  
Vol 9 ◽  
Author(s):  
Hamda Musabbah Alremeithi ◽  
Aljazia Khalfan Alghefli ◽  
Rouqyah Almadhani ◽  
Latifa Mohammad Baynouna AlKetbi

Population's preventive practices and self-isolation is determinantal in the prevention and mitigation. This study explored the adult population's knowledge, attitude, and practice toward COVID-19 in UAE between the 4th and 14th of April 2020. The study was a community-based, cross-sectional study using a self-administered electronic questionnaire covering five different aspects: demographics, knowledge, practice, attitude, source, and trust of information, and a patient health questionnaire (PHQ-2) for depression screening. Results were analyzed using frequencies, cross-tabulation, and regression analysis. A total of 1,867 people responded to the survey. The mean age of participants was 36.0 years S.D. 10.8. Males were 19.3% and female (80.7%). Knowledge was significantly better in people with higher educational levels (B 0.17, P-value &lt; 0.001), good preventive practice (B 0.12, P-value &lt; 0.001), and higher perceived risk scores (B 0.053, P-value = 0.025). The best practice scores were shown by participants with older age (B 0.097, P-value &lt; 0.05), with good knowledge (B 0.086, P-value &lt; 0.05), were of non-UAE nationalities (B −0.08, P-value &lt; 0.05), with jobs that cannot be practiced from home, military and health care employees (B −0.104, P-value &lt; 0.05), had a personal history of contact with COVID-19 patients (B 0.053, P-value &lt; 0.05), higher educational levels (B 0.052, P-value &lt; 0.05), and a positive attitude toward taking a vaccine (B 0.088, P-value &lt; 0.05). Depression risk was significantly higher in men, non-UAE nationals, in those with lower knowledge scores, and younger ages. The most followed practices were staying home, handwashing, avoiding social gatherings, limiting three people per vehicle, and avoiding public transportation. The least practiced measures were covering the face while sneezing or coughing and wearing masks. Although staying home was reported by 92.5% of participants, 22.6% mentioned that they were visited by more than two people and visited others in 18.4% during the last week. Social media was the source of information for 82.1% of the participants and most trusted doctors and healthcare providers. Depression risk was present in 18.9% of the participants, and most respondents (89%) agreed that SARS-COV-2 infection would be finally be successfully controlled. An encouraging finding is the willingness of two-third of the participants (64.5%) to take the COVID-19 vaccine and if it was developed, although it was very early in the pandemic. Only 14.6% said they would not take the vaccine, and 20.9% were not sure. The obtained results on knowledge and practices, although satisfactory, could be insufficient to prevent this pandemic from being contained. Therefore, we recommend the intensification of awareness programs and good practices. In addition, mental health is an area worth further studies.


2021 ◽  
pp. 12-14
Author(s):  
Monica Kalyanaraman ◽  
Parameswari Srijayanth ◽  
Srinivas Govindarajulu

Background: Coronavirus outbreak was a highly unpredicted global burden that caused millions of deaths across the world. Vaccination against the infection declines the morbidity and mortality rates. This study objective aims to determine the reasons for the vaccine acceptance. Methods: A cross sectional study was conducted through an online survey among the people living in chennai, Tamilnadu. An E-survey Google forms are circulated through the social platforms and email. Excluding the non-response all the data gained was descriptively analyzed. Results: Out of total (n =376 ≥ 18 years) participants majority of them showed High acceptance and got already vaccinated whereas some revealed the fear of vaccine safety and risk effects. Vaccine hesitancy is seen in terms of lack of trust and proper awareness, myths about adverse effects. In addition our ndings positively convey the knowledge of effective preventive measures for infection and proper following of government guidelines. Conclusion: The study outcomes even though shows willingness of the people in receiving the vaccine at some point still a notable interruption is seen. Prioritization should be given to those critical areas to inuence the public perception about vaccine benets because now vaccination is the only essential measure to suppress the healthcare pressure which halts the covid 19 infection.


2021 ◽  
Author(s):  
Neh Chang Ngasa ◽  
Stewart Ndutard Ngasa ◽  
Leticia Armelle Sani Tchouda ◽  
Eugénie Tanisso ◽  
Christabel Abanda ◽  
...  

Abstract Background: The production of the different COVID-19 vaccines has offered hope towards controlling the pandemic. Many governments around the world have been able to secure the number of doses required for the vaccination of their entire population. In Cameroon, the government’s strategy has been to secure the number of doses required to vaccinate frontline workers and other population at risk. A threat to this strategy could be vaccine hesitancy as demonstrated in previous studies. In this article we discussed the influence of spirituality on vaccine acceptance. We also examined other factors associated with vaccine acceptance amongst healthcare workers in Cameroon. Methods: This was a cross-sectional online survey of healthcare workers in Cameroon. Data was collected using Surveysparrow and then computed into Microsoft Excel. All analysis were done using Stata 14. Results: A total number of 371 healthcare workers took part in the survey and 45.38% indicated willingness to accept the vaccine if offered. The most common reason advanced for non-acceptance of the vaccine was negative perceptions about the efficacy of the vaccines. Independent factors associated with COVID-19 vaccine acceptance following a multivariate logistic regression included: being married (AOR 1.13, p< 0.01), presence of comorbidity (AOR:2.10, p<0.02), participants who had direct contact with covid patients (AOR: 3.34, p<0.01). Spirituality level was not independently associated with vaccine acceptance (AOR: 1.12, p<0.63). Conclusion: COVID-19 vaccine acceptance amongst healthcare workers in Cameroon is low. This is likely to reduce the vaccine uptake amongst healthcare workers. HCWs are in the best position to influence the uptake of these vaccines by the general population, therefore educating healthcare workers on the efficacy of these vaccines might improve their acceptance.


2021 ◽  
Vol 8 ◽  
Author(s):  
Mohammad Bellal Hossain ◽  
Md. Zakiul Alam ◽  
Md. Syful Islam ◽  
Shafayat Sultan ◽  
Md. Mahir Faysal ◽  
...  

This study assessed the preparedness regarding the preventive practices toward the coronavirus disease 2019 (COVID-19) among the adult population in Bangladesh. Data were collected through an online survey with a sample size of 1,056. We constructed four variables (individual, household, economic, and community and social distancing) related to preparedness based on the principal component analysis of eight items. We employed descriptive statistics and multiple linear regression analysis. The results showed that the accuracy rate of the overall preparedness scale was 68.9%. The preparedness level related to economic, individual, household, and community and social distancing was 64.9, 77.1, 50.4, and 83.2%, respectively. However, the economic preparedness significantly varied by sex, education, occupation, attitude, and worries related to COVID-19. Individual preparedness was significantly associated with education, residence, and attitudes. The household preparedness significantly varied by education, residence, and worries, while the respondent's community and social distancing-related preparedness significantly varied by sex, region, residence, and attitude. This study implies the necessity of the coverage of financial schemes for the vulnerable group. Increased coverage of health education regarding personal hygiene targeting the less educated and rural population should be ensured.


2021 ◽  
Vol 11 (1) ◽  
pp. 69-79
Author(s):  
Asma Ayyed AL-Shammary ◽  
Sehar un-Nisa Hassan ◽  
Aqeela Zahra ◽  
Fahad Bin Zafir Algahtani ◽  
Shadi Suleiman

Background: The expected second wave of the COVID-19 pandemic has started in various regions of the world. Public health experts warned that it could be as lethal as the first wave if people did not comply with self-protective measures. Currently, there is a gap in the literature on the relationship between peoples’ assessment of the effectiveness of community-based measures regarding adherence to self-protective behaviors for COVID-19 prevention and control. This study aimed to assess the role of the perceived effectiveness of community-based measures in adherence to self-protective behaviors during the COVID-19 pandemic. Methods: The cross-sectional online survey conducted from March 24 to June 22, 2020. The study sample Included 400 participants (49% male and 51% female) from the Kingdom of Saudi Arabia (KSA). The outcome measure was compliance to four self-protective behaviors i.e., "social distancing;" "wearing facemask;" "washing hands more frequently;" and "disinfecting surfaces in homes." We computed Chi-square statistics and odds ratios (ORs) using 95% confidence intervals (CIs). Results: The findings demonstrated that participants aged 25–34 years old were 25% less likely to comply with hand hygiene (OR = 0.75; 95% CI: 0.33–0.95) and social distancing (OR = 0.76; 95% CI: 0.34–0.98). Misconceptions related to COVID-19 significantly decreased compliance with self-protective behaviors by up to 27%. Participants who rated government decisions as useful were approximately 1.7 times more likely to comply with self-protective behaviors. Conclusion: Community-based measures should focus on engaging segments of the population That are currently less compliant. Health education policies should also focus on enhancing the perceived sense of control and personal responsibility and reduce anxiety levels. A continuous commitment to the implementation of preventive interventions and the clarification of misconceptions are required to combat the expected second wave.


2021 ◽  
Author(s):  
Diane Uschner ◽  
Matthew Bott ◽  
Michele Santacatterina ◽  
Mihili P Gunaratne ◽  
Lida Fette ◽  
...  

Importance: Real-world data are needed to assess incidence and factors associated with breakthrough SARS-CoV-2 infections following vaccination. Objective: Estimate incidence of breakthrough infections and assess associations with risk factors using self-reported data from a large NC population sample. Design: Prospective observational cohort study utilizing daily online survey data to capture information about COVID-19 symptoms, testing, and vaccination status. Setting: Six health care systems in North Carolina with data collected between January 15, 2021 and September 24, 2021. Participants: Adult study participants who reported full vaccination with a COVID-19 mRNA or J&J non-replicating viral vector vaccine (n = 16,020). Exposures: Potential community exposure to SARS-CoV-2. Main Outcome and Measures: Self-reported breakthrough infection. Results: SARS-CoV-2 infection after vaccination was self-reported in 1.9% of participants, with an incidence rate of 7.3 per 100,000 person-years. Younger age (45-64 vs. 18-44: HR (95% CI) = 0.65 (0.51-0.82); 65+ vs. 18-44: HR (95% CI) = 0.59 (0.39-0.90)), and vaccination with J&J Ad26.COV2.S were associated with a higher risk of breakthrough infection compared to vaccination with Pfizer BNT162b2 (Ad26.COV2.S vs. BNT162b2: HR (95% CI) = 2.23 (1.40-3.56)), while participants vaccinated with mRNA-1273 (mRNA-1273 vs. BNT162b2: HR (95% CI) = 0.69 (0.50-0.96) and those residing in urban counties experienced a lower rate of SARS-CoV-2 breakthrough infection compared with those from suburban (HR (95% CI) = 1.39 (1.01-1.90)) or rural (HR (95% CI) = 1.57 (1.16-2.11)) counties. There was no significant association between breakthrough infection and participant sex, race, healthcare worker status, prior COVID-19 infection, routine mask use, or overall vaccination rate in the county of residence. Conclusions and Relevance: This NC community-based observational study showed that the proportion of the cohort who self-report breakthrough SARS-CoV-2 infections was 7.3 events per 100,000 person-years. Younger adults, those vaccinated with J&J Ad26.COV2.S, and those residing in suburban or rural counties were at higher risk of breakthrough infections and should be targeted for additional risk mitigation strategies to decrease community transmission.


2019 ◽  
Author(s):  
Taylor McFadden ◽  
Michelle Fortier ◽  
Ryan McGinn ◽  
Brendan M Levac ◽  
Shane N Sweet ◽  
...  

AbstractBackgroundPhysical activity (PA) remains under prescribed by physicians. Motivation and confidence are clear drivers of frequency of promoting PA. Research shows demographic differences in physicians’ preventive practices, yet none have included medical students who form habits during training.ObjectivesStudy objectives were to (i) examine how Canadian medical students’ motivation to recommend PA to future patients differs according to six demographic variables (i.e. gender, ethnicity, year of study, university, proposed specialty and academic background) and (ii) examine how Canadian medical students’ confidence to recommend PA to future patients differs according to these same demographic variables.MethodsA cross-sectional design was used. First to fourth year medical students from three medical schools responded to an online survey (N = 221).ResultsFemale participants were more motivated to counsel patients on PA and refer to an exercise specialist compared to males (P < 0.01). Second year students were more motivated to assess a patients’ level of PA compared to third and fourth year students (P < 0.01). Students pursuing family medicine were more confident to assess and counsel compared to students pursuing paediatrics (P < 0.01).ConclusionGiven that motivation and confidence have a positive influence on frequency-promoting PA, these results suggest where future efforts should focus, to improve PA promotion in medical practice. Physical inactivity continues to be a major issue worldwide, and medical students as future physicians have a unique opportunity to enhance PA amongst the population.


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