scholarly journals A Novel Clinical Score Predicting the Presence of Fatty Pancreas

2021 ◽  
Vol 10 (24) ◽  
pp. 5843
Author(s):  
Tawfik Khoury ◽  
Amir Mari ◽  
Wisam Sbeit
Keyword(s):  
Fatty Liver ◽  
Predictive Value ◽  
Medical Center ◽  
Univariate Analysis ◽  
Clinical Score ◽  
Multivariate Regression Analysis ◽  
Cross Sectional ◽  
Diagnostic Score ◽  
Disease States ◽  
Fatty Pancreas

Background: Fatty pancreas (FP) has become an increasingly encountered entity in recent years. Several studies have shown an association with several disease states. Aims: we aimed to generate a simple non-invasive scoring model to predict the presence of FP. Method: We performed a retrospective cross-sectional analysis at Galilee Medical Center. Inclusion criteria included patients who underwent endoscopic ultrasound (EUS) for hepatobiliary indications and who had either hyperechogenic pancreas consistent with FP or no sonographic evidence of fatty pancreas. Results: We included 569 patients. Among them, 78 patients had FP by EUS and 491 patients did not have FP. On univariate analysis, obesity (odds ratio (OR) 5.11, p < 0.0001), hyperlipidemia (OR 2.86, p = 0.0005), smoking (OR 2.02, p = 0.04), hypertension (OR 2.58, p = 0.0001) and fatty liver (OR 5.94, p < 0.0001) were predictive of FP. On multivariate analysis, obesity (OR 4.02, p < 0.0001), hyperlipidemia (OR 2.22, p = 0.01) and fatty liver (OR 4.80, p < 0.0001) remained significantly associated with FP. We developed a diagnostic score which included three parameters that were significant on multivariate regression analysis, with assignment of weights for each variable according to the OR estimate. A low cut-off score of ≤1 was associated with a negative predictive value (NPV) of 98.1% for FP, whereas a high cut-off score of ≥2 was associated with a positive predictive value (PPV) of 35–56%. Conclusion: We recommend incorporating this simple score as an aid to identify individuals with FP.

A Validated Score Assessing the Risk of an Intra-Abdominal Abscess in Patients with Crohn’s Disease Presenting at the Emergency Department

2019 ◽  
Vol 13 (9) ◽  
pp. 1131-1137
Author(s):  
Tawfik Khoury ◽  
Saleh Daher ◽  
Muhammad Massarwa ◽  
David Hakimian ◽  
Ariel A Benson ◽  
...  
Keyword(s):  
Emergency Department ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Predictive Value ◽  
Univariate Analysis ◽  
Abscess Formation ◽  
Abdominal Abscess ◽  
Retrospective Case ◽  
Cross Sectional ◽  
Diagnostic Score

AbstractBackground and AimsA majority of acutely ill Crohn’s disease [CD] patients who present to Emergency Department [ED] will undergo an abdominal CT to rule out disease complications. We aimed to generate a simple non-invasive scoring model to predict the presence of an intra-abdominal abscess in CD patients in the ED.MethodsWe performed a retrospective case–control study at four Israeli hospitals from January 1, 2010 to May 30, 2018. Inclusion criteria included patients with an established diagnosis of CD that had cross-sectional abdominal imaging performed. A total of 322 patients were included, and 81 [25%] were diagnosed with an intra-abdominal abscess.ResultsIn univariate analysis, ileo–colonic location (odds ratio [OR] 1.88, p = 0.0148), perianal CD [OR 7.01, p = 0.0004], fever [OR 1.88, p = 0.0247], neutrophil-to-lymphocyte ratio [OR 1.12, p < 0.0001], and C-reactive protein [OR 1.10, p < 0.0001] were significantly associated with abscess formation, whereas current use of corticosteroids was negatively associated with abscess formation [OR 0.46, 95% CI, 0.2–0.88, p = 0.0192]. We developed a diagnostic score that included five parameters that were significant on multivariate regression analysis, with assignment of weights for each variable according to the coefficient estimate. A low cut-off score of ≤7 was associated with a negative predictive value [NPV] of 93% for abscess formation, whereas a high cut-off score of >9 was associated with a positive predictive value of 65%. We validated this score with an independent cohort [area under the curve of 0.881 and NPV of 98.5%].ConclusionWe recommend incorporating this score as an aid for stratifying acutely ill CD patients in the ED with low or high probability of the presence of an intra-abdominal abscess.

Antibiotic Susceptibility Evaluation of Bacterial Agents Causing Infection in Children with Acute Tonsillopharyngitis

2020 ◽  
Vol 20 ◽  
Author(s):  
Hamidreza Sherkatolabbasieh ◽  
Majid Firouzi ◽  
Shiva Shafizadeh ◽  
Iman Amiri
Keyword(s):  
Sore Throat ◽  
Predictive Value ◽  
Positive Culture ◽  
Clinical Score ◽  
Streptococcal Pharyngitis ◽  
Diffusion Method ◽  
Disk Diffusion Method ◽  
Cross Sectional ◽  
Clinical Sensitivity ◽  
Group A

Background: The aim of this study is to evaluate the prevalence of group A beta-hemolytic pharyngitis by assessing the outcome of the culture and the resistance and sensitivity of group A beta hemolytic streptococcus to antibiotics. Methods: This cross-sectional study was conducted on 170 patients, aged 3-15 years, referred to the clinic with complaints of sore throat. Patients’ history was collected and physical examination was performed and were score based on clinical findings. Patients with other underlying pathologies and those taking antibiotics prior to the study were excluded from our study. Antimicrobial susceptibility test was performed by disk diffusion method against cephalexin, cefazolin, erythromycin and amoxicillin. Results: A total of 170 patients were reported with sore throat. Patients with positive culture results were 60% male and 40% female. Amoxicillin resistance was the greatest (5%) in the culture. All isolated bacteria were sensitive to amoxicillin, cephalexin, cefazolin and erythromycin. Patients with McIssac score ≥ 6 showed clinical sensitivity 75% specificity 61% negative predictive value 94.8% and positive predictive value 20.3% for Group A beta-hemolytic streptococcal pharyngitis. Conclusion: The results showed the higher the clinical score, the greater the chance of positive throat culture.

scholarly journals St. George’s Respiratory Questionnaire (SGRQ) sebagai Alat Bantu Diagnostik serta Prediktor Terjadinya Chronic Pulmonary Aspergillosis (CPA) pada Pasien Tuberkulosis Paru Pasca Terapi

2021 ◽  
Vol 3 (1) ◽  
pp. 1
Author(s):  
William S. Wangko ◽  
Indra Kurniawan ◽  
Maarthen C. P. Wongkar ◽  
Agung Nugroho ◽  
Efata B Polii
Keyword(s):  
Diagnostic Tool ◽  
Predictive Value ◽  
Clinical Signs ◽  
Clinical Score ◽  
Pulmonary Aspergillosis ◽  
Cross Sectional ◽  
Lung Tuberculosis ◽  
St George's Respiratory Questionnaire ◽  
Chronic Pulmonary Aspergillosis ◽  
Post Therapy

Abstract: Patients of post therapy lung tuberculosis (TB) that still have permanent or worsened clinical signs might be caused by chronic pulmonary aspergillosis (CPA). Diagnosis of CPA is difficult to confirmed without complete supporting tests. This study was aimed to establish whether Saint George’s Respiratory Questionnaire (SGRQ) could be used as diagnostic tool and predictor of the occurence of CPA in post therapy lung TB patients. This was an analytical observational study with a cross sectional design. There were 72 patients who had negative Gene Xpert sputum; 34.7% with positive Aspergillus-specific IgG. Their clinical signs were evaluated with SGRQ. The results showed that there was a very significant relationship between clinical score and CPA (p<0.0001). The lower the clinical score the less the probability of CPA. In this analysis we determined the diagnosis value of clinical score with a probability cut-off point = 0.5 which led to clinical score cut-off point of 45.6 with further results, as follows: sensitivity 68.0%; specificity 95.7%; positive predictive value 89.5%; negative predictive value 84.9%; OR 47.8, and CI 95% (9,2-248,2). In conclusion, SGRQ could be used as diagnostic tool and predictor of the occurence of CPA in post therapy lung TB patients.Keywords: post therapy lung TB; chronic pulmonary aspergillosis; Saint George’s Respiratory Questionnaire (SGRQ)  Abstrak: Pasien TB paru pasca terapi yang masih memperlihatkan gejala klinis menetap atau bahkan memberat dapat disebabkkan oleh adanya chronic pulmonary aspergillosis (CPA). Diagnosis CPA sulit ditegakkan tanpa adanya pemeriksaan penunjang yang lengkap. Penelitian ini bertujuan untuk menentukan apakah Saint George’s Respiratory Questionnaire (SGRQ) dapat menjadi alat bantu diagnostik serta prediktor terjadinya CPA pada pasien TB paru pasca terapi. Jenis penelitian ialah analitik observasional dengan desain potong lintang. Hasil penelitian mendapatkan 72 pasien dengan sputum Gene Xpert negatif (34,7% dengan positif IgG Aspergillus) dilakukan penilaian skor klinis menggunakan SGRQ. Hasil uji menunjukkan terdapat hubungan sangat bermakna antara skor klinis dengan terjadinya CPA (p<0,0001). Makin rendah skor klinis makin kecil peluang terjadinya CPA. Melalui analisis ini dapat ditentukan nilai diagnosis skor klinis SGRQ dengan mengambil titik potong peluang = 0,5. Nilai peluang = 0,5 memberikan titik potong skor klinis = 45,6.  Dengan titik potong skor klinis SGRQ = 45,6 diperoleh nilai-nilai diagnosis sebagai berikut: Sensitivitas = 68,0%; Spesifisitas = 95,7%; Nilai Prediksi Positif = 89,5%; Nilai Prediksi Negatif = 84,9%; OR = 47,8 dengan CI 95% (9,2-248,2). Simpulan penelitian ini ialah SGRQ dapat menjadi alat bantu diagnostik serta prediktor terjadinya CPA pada pasien TB paru pasca terapi.Kata kunci: tuberkulosis paru pasca terapi; chronic pulmonary aspergillosis; Saint George’s Respiratory Questionnaire (SGRQ)

scholarly journals Exploring the Relationship Between Serum Magnesium, Inflammation, and Chronic Pain in a Vermont Primary Care Population

2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1821-1821
Author(s):  
Benjamin Littenberg ◽  
Thomas Ahern ◽  
Emily Tarleton
Keyword(s):  
Primary Care ◽  
Chronic Pain ◽  
Medical Center ◽  
Primary Care Patient ◽  
Serum Magnesium ◽  
Random Noise ◽  
Univariate Analysis ◽  
Care Patient ◽  
Cross Sectional ◽  
The Relationship

Abstract Objectives We sought to describe the relationship between serum magnesium, inflammation, and chronic pain in adult primary care patient. Methods We sought to describe this relationship utilizing a cross-sectional analysis of medical records from 5639 adults (mean age 59 years; 42% men) seen in The University of Vermont Medical Center primary care clinics between 2015 and 2018. Patients with at least one serum magnesium level, C-reactive protein (CRP, a measure of inflammation) level, and chronic pain score (self-reported visual analogue scale) were included. Results Univariate analysis confirmed the relationship between serum magnesium and chronic pain (−0.31 points/mg/dL; 95% CI −0.47, −0.14; P &lt; 0.001). However, when serum magnesium and CRP were both included in the model, the relationship with pain is unclear (N = 1345; CI −0.003, 0.002; P = 0.69). Conclusions For adults seen in primary care, lower serum magnesium levels are associated with chronic pain. This inverse relationship is not explained by random noise, including age and gender. The complex relationship between serum magnesium, CRP, and pain is complex requires further exploration. Funding Sources None.

scholarly journals Effect of Type 2 Diabetes Mellitus on the Hypoxia-Inducible Factor 1-Alpha Expression. Is There a Relationship with the Clock Genes?

2020 ◽  
Vol 9 (8) ◽  
pp. 2632
Author(s):  
Carolina López-Cano ◽  
Liliana Gutiérrez-Carrasquilla ◽  
Ferran Barbé ◽  
Enric Sánchez ◽  
Marta Hernández ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Clock Genes ◽  
Univariate Analysis ◽  
Hypoxia Inducible Factor ◽  
Multivariate Regression Analysis ◽  
Cross Sectional Study ◽  
Orphan Receptor ◽  
Cross Sectional ◽  
Patients With Diabetes

Limited reports exist on the relationships between regulation of oxygen homeostasis and circadian clock genes in type 2 diabetes. We examined whether the expression of Hypoxia-Inducible Factor-1α (HIF-1α) and HIF-2α relates to changes in the expression of clock genes (Period homolog proteins (PER)1, PER2, PER3, Retinoid-related orphan receptor alpha (RORA), Aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL), Circadian locomotor output cycles kaput (CLOCK), and Cryptochrome proteins (CRY) 1 and CRY2) in patients with type 2 diabetes. A total of 129 subjects were evaluated in this cross-sectional study (48% with diabetes). The gene expression was measured by polymerase chain reaction. The lactate and pyruvate levels were used as surrogate of the hypoxia induced anaerobic glycolysis activity. Patients with diabetes showed an increased plasma concentration of both lactate (2102.1 ± 688.2 vs. 1730.4 ± 694.4 uM/L, p = 0.013) and pyruvate (61.9 ± 25.6 vs. 50.3 ± 23.1 uM/L, p = 0.026) in comparison to controls. However, this finding was accompanied by a blunted HIF-1α expression (1.1 (0.2 to 5.0) vs. 1.7 (0.4 to 9.2) arbitrary units (AU), p ≤ 0.001). Patients with diabetes also showed a significant reduction of all assessed clock genes’ expression. Univariate analysis showed that HIF-1α and almost all clock genes were significantly and negatively correlated with HbA1c concentration. In addition, positive correlations between HIF-1α and the clock genes were observed. The stepwise multivariate regression analysis showed that HbA1c and clock genes independently predicted the expression of HIF-1α. Type 2 diabetes modifies the expression of HIF-1α and clock genes, which correlates with the degree of metabolic control.

scholarly journals Faktor – Faktor Yang Berhubungan Dengan Disiplin Kerja Karyawan Non Medis Di Rumah Sakit Pekanbaru Medical Center (PMC) Tahun 2020

2021 ◽  
Vol 1 (2) ◽  
pp. 170-181
Author(s):  
Nurhafiza Fiza(Fiza) ◽  
Aldiga Rienarti Abidin ◽  
Arief Wahyudi
Keyword(s):  
Health Workers ◽  
Medical Center ◽  
Univariate Analysis ◽  
Sampling Technique ◽  
Bivariate Analysis ◽  
P Value ◽  
Cross Sectional ◽  
Leadership Models ◽  
Center Hospital ◽  
Medical Center Hospital

ABSTRAK Keberhasilan suatu rumah sakit dipengaruhi oleh tenaga kesehatan atau sumber daya manusia yang disiplin, yang mencerminkan kesadaran dan kesediaan mentaati semua peraturan perusahaan dan norma-norma sosial yang berlaku. Faktor-faktor yang mempengaruhi disiplin  kerja diantaranya ketepatan waktu, pemanfaatan sarana, balas jasa, tanggung jawab dan ketaatan terhadap aturan. Tujuan penelitian untuk mengetahui faktor-faktor yang berhubungan dengan disiplin kerja karyawan non medis di Rumah Sakit Pekanbaru Medical Center. Jenis penelitian kuantitatif dengan desain analitik Cross Sectional study.Populasi dalam penelitian ini adalah seluruh tenaga non medis di Rumah Sakit Pekanbaru Medical Center (PMC) yang berjumlah 70 orang . Teknik sampling yang digunakan adalah teknik total sampling. Analisis Univariat dilakukan untuk mendeskripsikan karakter masing-masing variabel yang diteliti, sedangkan analisis Bivariat dilakukan untuk mengetahui hubungan kedua variabel independen dan dependen. teladan pemipin P value 0.016, balas jasa P value 0.000, keadilan P value 0.000, pengawasan melekat P value 0.011, sanksi hukuman P value 0.008 dengan disiplin kerja. Ada hubungan antara teladan pemipin, balas jasa, keadilan, sanksi hukuman. Di sarankan agar Rumah Sakit Pekanbaru Medical Center (PMC) dapat meningkatkan penerapan prinsip keadilan dalam lingkungan kerjanya untuk dapat meningkatkan disiplin kerja karyawan ABSTRACT The success of a hospital is influenced by health workers or human resources who are disciplined, which reflects the awareness and willingness to obey all company regulations and applicable social norms. Factors affecting work discipline include timeliness, utilization of facilities, remuneration, responsibility and adherence to rules. The purpose of this study was to determine the factors related to the work discipline of non-medical employees at Pekanbaru Medical Center Hospital. This type of quantitative research is analytic cross sectional study design. The population in this study is all non-medical staff at Pekanbaru Medical Center Hospital, amounting to 70 people. The sampling technique used was total sampling technique. Univariate analysis was carried out to describe the character of each variable under study, while Bivariate analysis was carried out to see the relationship between the two independent and dependent variables. leadership models P value 0.016, reward P value 0.000, fairness P value 0.000, supervision attached P value 0,11, sanctions P value 0.008. There is a relationship between leadership models, reward, fairness, supervision attached, sanctions. it is recommended that Pekanbaru Medical Center Hospital to increase the implementation of fairness principle in the work environment in order to improve employee’s discipline Pekanbaru Medical Center Hospital  

scholarly journals Faktor-Faktor Yang Mempengaruhi Burnout Pada Perawat Diruang Rawat Inap RS PMC

2019 ◽  
Vol 2 (3) ◽  
pp. 144
Author(s):  
Awaliyah Ulfah Ayudytha ◽  
Desta Asherti Putri
Keyword(s):  
Leadership Style ◽  
Significant Relationship ◽  
Medical Center ◽  
Univariate Analysis ◽  
Sampling Technique ◽  
Bivariate Analysis ◽  
Chi Square ◽  
Cross Sectional ◽  
Center Hospital ◽  
Medical Center Hospital

<p><em>Burnout is a prolonged response related to stressors that continue to occur in the workplace where the result is a combination of workers and jobs. Nurse fatigue occurs when nurses work more than 80% of their work time. The purpose of this study was to determine the factors that influence burnout in nurses in the inpatient room of Pekanbaru Medical Center hospital in 2019.This research method was descriptive correlation with cross sectional approach done to 35 respondents. Sampling technique using total sampling method. The analysis used is univariate analysis and bivariate analysis using Chi-square test. The results showed that there was a significant relationship between workload and burnout (p = 0.024) and there was a significant relationship between leadership style and burnout (p = 0.027). Based on the results of these studies, the researchers recommend that the management of Pekanbaru Medical Center Hospital pay more attention to the level of burnout nurses because the performance of nurses plays an important role in patient care. </em></p>

scholarly journals CHA2DS2-VASc, a Simple Clinical Score Expanding Its Boundaries To Predict Contrast Induced Acute Kidney Injury After Primary Percutaneous Coronary Interventions

2021 ◽  
Author(s):  
Rajesh Kumar ◽  
Mahesh Kumar Batra ◽  
Sanam Khowaja ◽  
Ali Ammar ◽  
Ashok Kumar ◽  
...  
Keyword(s):  
Predictive Value ◽  
Multivariable Analysis ◽  
Area Under The Curve ◽  
Clinical Score ◽  
Left Ventricular ◽  
Left Ventricular Ejection ◽  
Primary Pci ◽  
Cross Sectional ◽  
Ventricular Ejection Fraction ◽  
Percutaneous Coronary

Abstract Background Promising results of CHA2DS2-VASc score have been reported for the prediction of contrast induced nephropathy (CIN) after percutaneous coronary intervention (PCI). However, data of its predictive strength in the context of primary PCI is not available. Therefore, in this study, we have assessed predictive value of CHA2DS2-VASc score for CIN after primary PCI. Methodology : This analytical cross-sectional study was conducted between January 2021 and June 2021 at the National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan. Inclusion criteria of the study was consecutive adult patients undergone primary PCI. Baseline CHA2DS2-VASc score was calculated and either 25% or 0.5 mg/dL increase in post-procedure serum creatinine level as compared to baseline level was categorized as CIN. Results A total of 691 patients were included, of which 82.1% (567) were male. CIN after primary PCI was observed in 63 (9.1%) patients out of which 66.7% (42) patients had CHA2DS2-VASc score of ≥ 2. The area under the curve (AUC) for the score was 0.725 [0.662 to 0.788] with sensitivity and specificity of 66.7% [63.1–70.2%] and 66.7% [53.7–78.1%] respectively at cut-off value of ≥ 2. In multivariable analysis, left ventricular ejection fraction ≤ 30% and CHA2DS2-VASc ≥ 2 were found to be independent predictors with adjusted odds ratios of 2.19 [1.06–4.5] and 2.13 [1.13–4.01] respectively. Conclusions CHA2DS2-VASc score has good predictive value for the prediction of CIN after primary PCI. Criteria of CHA2DS2-VASc ≥ 2 can be used for the risk stratification of CIN after primary PCI.

scholarly journals A Novel Biomarker Panel to Identify Steroid Resistance in Childhood Idiopathic Nephrotic Syndrome

2017 ◽  
Vol 12 ◽  
pp. 117727191769583 ◽  
Author(s):  
Michael R Bennett ◽  
LaTawnya Pleasant ◽  
Christopher Haffner ◽  
Qing Ma ◽  
Wendy D Haffey ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Idiopathic Nephrotic Syndrome ◽  
Medical Center ◽  
Univariate Analysis ◽  
Steroid Resistance ◽  
Absolute Quantitation ◽  
Cross Sectional ◽  
Fetuin A ◽  
Acid Glycoprotein ◽  
Neutrophil Gelatinase Associated Lipocalin

Idiopathic nephrotic syndrome (NS) is the most common glomerular disorder of childhood. Response to initial treatment with corticosteroids is an indicator of prognosis, as resistant patients often present more progressive disease. In this cross-sectional pilot study, we set out to discover a panel of noninvasive biomarkers that could distinguish steroid-resistant nephrotic syndrome (SRNS) from steroid-sensitive nephrotic syndrome (SSNS). Information gleaned from such a panel could yield more individualized treatment plans and prevent unnecessary steroid exposure in patients unlikely to respond. Urine was collected from 50 pediatric patients diagnosed with idiopathic NS at Cincinnati Children’s Hospital Medical Center. Isobaric tags for relative and absolute quantitation (iTRAQ) was used to discover 13 proteins that were differentially expressed in SSNS vs SRNS in a small 5 × 5 discovery cohort. Suitable assays were found for 9 of the 13 markers identified by iTRAQ and were used in a 25 SRNS × 25 SSNS validation cohort. Vitamin D–binding protein (VDBP), alpha-1 acid glycoprotein 1 (AGP1), alpha-1 acid glycoprotein 2 (AGP2), alpha-1-B glycoprotein (A1BG), fetuin-A, prealbumin, thyroxine-binding globulin and hemopexin, and alpha-2 macroglobulin were measured and combined with urine neutrophil gelatinase–associated lipocalin (NGAL), which had been previously shown to distinguish patients with SRNS. Urinary VDBP, prealbumin, NGAL, fetuin-A, and AGP2 were found to be significantly elevated in SRNS using univariate analysis, with area under the receiver operating characteristic curves (AUCs) ranging from 0.65 to 0.81. Multivariate analysis revealed a panel of all 10 markers that yielded an AUC of 0.92 for identification of SRNS. A subset of 5 markers (including VDBP, NGAL, fetuin-A, prealbumin, and AGP2) showed significant associations with SRNS and yielded an AUC of 0.85.

scholarly journals Role of drug-induced sleep endoscopy in evaluation of positional vs non-positional OSA

2020 ◽  
Vol 49 (1) ◽  
Author(s):  
Ming-Chin Lan ◽  
Stanley Yung-Chuan Liu ◽  
Ming-Ying Lan ◽  
Yun-Chen Huang ◽  
Tung-Tsun Huang ◽  
...  
Keyword(s):  
Medical Center ◽  
Academic Medical Center ◽  
Univariate Analysis ◽  
Lateral Wall ◽  
Treatment Modalities ◽  
Sleep Endoscopy ◽  
Drug Induced ◽  
Cross Sectional ◽  
Drug Induced Sleep Endoscopy ◽  
Positional Dependency

Abstract Background The study aimed to evaluate the anatomical differences between positional and non-positional OSA, and to identify the potential predictors for distinguishing between these two types of OSA. Methods A cross-sectional study of 230 consecutive patients with OSA undergoing DISE (Drug-induced Sleep Endoscopy) was carried out at a tertiary academic medical center. The factors correlating with positional and non-positional OSA were analyzed, including clinical characteristics, polysomnography data, and DISE findings. Results Univariate analysis revealed that non-positional dependency was correlated with a higher BMI (p < 0.001), neck circumference (p < 0.001), modified Mallampati score (p = 0.003), AHI (p < 0.001), degree of velum concentric collapse (p = 0.004), degree of oropharyngeal lateral wall collapse (p < 0.001), and degree of tongue base anteroposterior collapse (p = 0.004). Multivariate analysis revealed that oropharyngeal lateral wall collapse (OR = 1.90, p = 0.027) was the only anatomical factor significantly predicted non-positional dependency in OSA patients. AHI (OR = 1.04, p < 0.001), although significant, made only a marginal contribution to the prediction of non-positional dependency. Conclusions Oropharyngeal lateral wall collapse was identified as the only anatomical predictor for non-positional dependency in OSA patients. Therefore, further treatment modalities should address the distinct anatomical trait between positional and non-positional OSA. Graphical abstract

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