COVID-19 Severity and Comorbidities in Diabetic Patients

Background: This study aimed to investigate the demographic factors, comorbidities, and laboratory results of diabetic patients with coronavirus disease 2019 (COVID-19) severity. Materials and Methods: This cross-sectional study enrolled 171 diabetic patients with COVID-19 admitted based on chest CT scan findings to the COVID-19 ward of Shahid Mohammadi Hospital in Hormozgan, Iran from 1 March to 1 June, 2020. Reverse-transcriptase polymerase chain reaction (RT-PCR) test was performed, and the patients were divided into three groups (mild, moderate, and severe) based on the severity of disease. Then we investigated the demographic factors, comorbidities, and laboratory results of diabetic patients with severe COVID-19 severity. Results: Regarding comorbidities, there was no significant difference between the three groups. Moreover, there was a significantly lower lymphocyte count in the severe group compared to moderate and mild groups (P = 0.001). We showed the increase in blood urea nitrogen (BUN) and creatinine to be significantly associated with increased disease severity (P = 0.001 and P = 0.009, respectively). We also showed a significant difference in aspartate aminotransferase (AST) levels between different groups of patients (P = 0.002) with a higher level of AST in the severe group (P = 0.020). Lactate dehydrogenase (LDH) and troponin were also significantly associated with an increase in COVID-19 severity in patients with diabetes (P = 0.013 and P = 0.002, respectively). Conclusion: There was a significant association between disease severity and BUN, creatinine, AST, LDH, and troponin levels in diabetic patients with COVID-19. There was no significant association between different groups regarding severity of disease and comorbidities.

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Psychiatric Disorders in Diabetic Patients in Rafsanjan

Psychological Disorders and Research ◽

10.31487/j.pdr.2021.01.02 ◽

2021 ◽

pp. 1-4

Author(s):

Reza Bidaki ◽

Parvin Agha Mohamad Hasani ◽

Maryam Alireza Zade ◽

Rezvan Sadr Mohammadi ◽

Reza Bidaki ◽

...

Keyword(s):

Psychiatric Disorders ◽

Common Mental Disorders ◽

Risk Groups ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Sectional Study ◽

Cross Sectional ◽

Demographic Questionnaire ◽

Patients With Diabetes ◽

Diabetes Center

Objective: To determine prevalence rates, associated features, and risk factors for psychiatric disorders subsequent to the diagnosis of IDDM. Methods: In this cross-sectional study were been selected 100 randomly who referred to Rafsanjan Diabetes Center. The data of this study is gathered demographic questionnaire and Minnesota Multi-phasic Personality Inventory (MMPI). Data was analysed with software SPSS-17. Results: 76% of the patients were female and 24% were men 45.4% of the illiterate population. The results showed hypochondriasis (22%) and schizophrenia (19%) and depression (11%) are three psychiatric disorders that patients with diabetes in high-risk groups have reported. Conclusion: The present study demonstrated that about 30-45% of patients with diabetes suffered from common mental disorders. The prevalence of some psychiatric disorders is considerable in diabetic patients in Rafsanjan.

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Myeloperoxidase as an Important Predictor of Cardiovascular Risk in Individuals with Rheumatoid Arthritis

10.21203/rs.3.rs-641421/v1 ◽

2021 ◽

Author(s):

Elisangela Gueiber Montes ◽

Fabiana Postiglioni Mansani ◽

Alceu de Oliveira Toledo Júnior ◽

Marcelo Derbli Schafranski ◽

Bruno Queiroz Zardo ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Cardiovascular Risk ◽

Cross Sectional Study ◽

Important Predictor ◽

Diabetic Patients ◽

Glucocorticoid Treatment ◽

Cross Sectional ◽

Significance Level ◽

Dose Time ◽

Significant Difference

Abstract Background: Rheumatoid arthritis is an inflammatory disease with joint manifestations. In the presence of extra-articular manifestations, the morbidity and severity of the disease increases. Glucocorticoid is used as a treatment and may result in side effects related to cardiovascular risk. Methods: This was a cross-sectional study including 59 volunteers with rheumatoid arthritis receiving treatment at a Hospital of Campos Gerais, that aimed to establish the relation between cardiovascular risk, glucocorticoid treatment and myeloperoxidase in these patients. Subjects were divided into two groups: using (n = 39) and without glucocorticoids (n = 20). They underwent clinical evaluation, physical examination and blood samples were taken. Statistical analysis was performed using Student's t-test and Mann-Whitney test. Logistic regression was performed to assess cardiovascular risk. The significance level was 5% (α = 0.05). Calculations were performed using the Statistical Package for the Social Science version 21.0. Results: There has been a significant difference between groups in blood glucose values (p = 0.012), that can be explained by the different percentage of diabetic patients in the groups. When assessed cardiovascular risk using the predictors of glucocorticoid dose, time of glucocorticoid use, myeloperoxidase, and C-reactive protein together, these were responsible for significantly predicting cardiovascular risk (p = 0.015). Conclusions: A significant relation between the predictor myeloperoxidase alone was also demonstrated (p = 0.037), may it be an important predictor of cardiovascular risk among individuals with rheumatoid arthritis.

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Adherence of Patients with Diabetes to a Lifestyle Advice and Management Plan in Basra, Southern Iraq

International Journal of Diabetes and Metabolism ◽

10.1159/000500915 ◽

2019 ◽

Vol 25 (3-4) ◽

pp. 100-105 ◽

Cited By ~ 3

Author(s):

Rawnaq Adil Aladhab ◽

Majid Hameed Alabbood

Keyword(s):

Management Plan ◽

Cross Sectional Study ◽

Complex Problem ◽

Common Reason ◽

Diabetic Patients ◽

Lifestyle Advice ◽

Cross Sectional ◽

Adherence To Medication ◽

Patients With Diabetes ◽

Southern Iraq

Background: Poor adherence to treatment regimens is a complex problem, especially for those with chronic illnesses. Noncompliance is believed to be the most common reason for treatment failure in diabetic patients, leading to the absence of metabolic control and accelerating disease-related complications. Data on the adherence of people with diabetes in Iraq are lacking. Objectives: The purpose of this study was to measure the rate of adherence among Iraqi patients with diabetes. Methods: This was a cross-sectional study conducted in the Specialized Endocrine and Diabetes Center in Basra, southern Iraq, during the period from June to August 2018. Data were collected by completing an interviewing questionnaire consisting of 13 questions. Results: A total of 231 patients were included in the study (54.5% were female). Mean age was 51.85 ± 13.55 years. 65.4% of the participants were taking their medications at the right times. The most common reason for not taking their medication (48.8%) was difficulty in remembering the dosage times. 40.7% of the participants were sedentary. Only one-third of the patients followed their doctors’ instructions regarding diet. Conclusions: The rate of adherence to medication regimens and lifestyle advice was unsatisfactory in this study group. The awareness of diabetic patients and their caring physicians about the importance of adherence to therapy, exercise, and diet should be emphasized.

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Comparison of ox-LDL Levels in Diabetic Patients with Normo-, Micro-, and Macroalbuminuria with Their First Degree Relatives and the Healthy Control Group

International Journal of Endocrinology ◽

10.1155/2012/167154 ◽

2012 ◽

Vol 2012 ◽

pp. 1-5 ◽

Cited By ~ 3

Author(s):

Parisa Behzadi ◽

Firouzeh Torabi ◽

Massoud Amini ◽

Ashraf Aminorroaya

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Cross Sectional Study ◽

Control Group ◽

Diabetic Patients ◽

Cross Sectional ◽

First Degree Relatives ◽

Significant Difference ◽

Healthy Control ◽

And Control

Oxidized low density lipoprotein (ox-LDL) is a product of oxidative stress. In this cross-sectional study, we compared the ox-LDL concentrations in diabetic patients with normoalbuminuria (n=28), microalbuminuria (n=28), and macroalbuminuria (n=28) with their first degree relatives (n=28) and healthy control people (n=31). They were selected by consecutive patient selection method. The ox-LDL level was assayed using ELISA. We measured blood pressure, lipid profile, fasting plasma glucose (FPG), and HbA1c in all groups. There was no significant difference in ox-LDL concentrations among normoalbuminuric, microalbuminuric, and macroalbuminuric diabetic groups. In diabetic patients with micro- and macroalbuminuria, ox-LDL concentration was higher than their first degree relatives (P=0.04andP=0.03) and control group (P=0.001andP=0.03, resp.). In normoalbuminuric diabetic persons, ox-LDL concentration was just higher than that of healthy people (P=0.02). There was no statistically significant difference in ox-LDL levels between normoalbuminuric diabetic patients and their first degree relatives. In conclusion, the presence and progression of albuminuria in diabetic patients are not related to ox-LDL concentration and genetic predisposition influences the plasma OX-LDL level. Larger sample size is needed to confirm this conclusion in future studies.

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Factors associated with wound healing outcome among Diabetic Foot patients- A cross sectional Study

International Journal of AYUSH Case Reports ◽

10.52482/ijacare.v5i1.170 ◽

2021 ◽

Vol 5 (1) ◽

pp. 36-46

Author(s):

M Jayalakshmi ◽

P Thenmozhi

Keyword(s):

Diabetic Foot ◽

Foot Ulcer ◽

Diabetic Foot Ulcer ◽

Cross Sectional Study ◽

Wound Management ◽

Diabetic Patients ◽

Foot Care ◽

Cross Sectional ◽

Patients With Diabetes ◽

One Year

Diabetic foot ulcer (DFU) has been identified as the leading reason for hospitalization among patients with diabetes. Patients with diabetes are at greater risk of complications, the most important of them are diabetic neuropathy and peripheral vascular disorders leading to the development of foot ulcers. The problem is generally faced and as well is considered as one among the most common complications of diabetes that affect millions of people all over the world. The current study, aimed to document the clinical profile and healing outcome of diabetic foot ulcer management which may become guidance for further improvement in wound management among diabetic foot ulcer patients. Cross sectional descriptive study was conducted over one-year period of time. A total of 246 Diabetic patients with a foot ulcer of Grade 1 to 3 participated in the study. Patients with higher grade ulcers of Grade 4 and 5 were excluded from the study. Final data analysis of 160 patients was done using SPSS version 20. The prevalence of Grade 2 and 3 ulcers were observed 54.37% and 31.8 % while Grade 1 ulcer was observed 13.75%. No risk factors were found to be significantly associated with diabetic foot ulcer. Wound was healed well in 50 % and partially healed in 21 % of the participants. Wound remains unchanged in 3 % of study participants, while 8% of participants underwent toe amputation. Foot ulceration is a preventable in many diabetic patients with adequate education, routine foot care and attention to foot wear.

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A study to assess the correlation between HbA1c and microalbuminuria among diabetics

International Journal of Advances in Medicine ◽

10.18203/2349-3933.ijam20205454 ◽

2020 ◽

Vol 8 (1) ◽

pp. 16

Author(s):

Sruthi Kare ◽

Vishwanath N. Reddy ◽

Thejdeep Mahamkali

Keyword(s):

Diabetes Mellitus ◽

Diabetic Nephropathy ◽

Socioeconomic Development ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Cross Sectional ◽

Duration Of Diabetes ◽

Medical College ◽

Significant Linear Correlation ◽

Patients With Diabetes

Background: India is one of the epicentres of the global diabetes mellitus pandemic. Rapid socioeconomic development and demographic changes, along with increased susceptibility for Indian individuals, have led to the explosive increase in the prevalence of diabetes mellitus in India over the past four decades. Diabetic Nephropathy is a common consequence of long-standing diabetes mellitus. The development of diabetic nephropathy has a dramatic increase on the morbidity and mortality of patients with diabetes. Objective of this study was to evaluate the prevalence of microalbuminuria in patients with diabetes mellitus patients. Methods: This cross-sectional study was conducted on T 2 diabetes mellitus patients visiting medicine OPD of R L Jalappa hospital constituent hospital of Sri Deveraj Urs Medical College, Tamaka, Kolar from May 2016 to July 2016. A total of 60 type-2 diabetes patients were enrolled in the study.Results: Average duration of diabetes among study group was 8 years and most of the patients were between 6-10 years. In type 2DM patients, microalbuminuria and glycemic control have shown a significant linear correlation with duration of diabetes (p<0.05). Also, micro albuminuria has a significant correlation with increase in level of glycosylated haemoglobin. Conclusions: The prevalence of microalbuminuria in diabetic patients was found to be high and being a developing country; there is a dire need that microalbuminuria and HbA1c testing should be done in both, newly diagnosed as well as already diagnosed type 2DM patients as an early marker of renal risk factor.

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Clinical course and outcome in diabetic patients with COVID-19

Immunopathologia Persa ◽

10.34172/ipp.2021.23 ◽

2020 ◽

Vol 7 (2) ◽

pp. e23-e23

Author(s):

Zahra Davoudi ◽

Ilad Alavi Darazam ◽

Farnaz Saberian ◽

Sina Homaee ◽

Shervin Shokouhi ◽

...

Keyword(s):

Glycated Hemoglobin ◽

Clinical Course ◽

Severe Disease ◽

Invasive Mechanical Ventilation ◽

Cross Sectional Study ◽

Diabetic Patients ◽

Cross Sectional ◽

Risk Of Death ◽

Patients With Diabetes ◽

The Mean

Introduction: As diabetes is highly prevalent worldwide, understanding particular dimensions of COVID-19 infection in diabetic patients is of significant importance. Objectives: The present research aimed to evaluate the outcome of diabetic patients with COVID-19 infection, and the clinical and biochemical characteristics in survived and non-survived patients. Patients and Methods: The present single-center, cross-sectional study examined laboratory and clinical features of 160 patients with diabetes who had moderate to severe criteria. The obtained data were categorized as survived or non-survived patients and then we compared the clinical characteristics in two groups. Results: In this study, 160 diabetic patients (75 men and 85 women) admitted with moderate to severe Covid-19 were evaluated. The mean age of studied patients was 51-90 years old, with diabetes duration of 5 to 15 years. One hundred thirty-one patients (81.9%) survived, but twenty-nine patients (18.1%) did not survive. Regarding the comparison of symptoms, only the loss of consciousness on admission was higher in non- survived patients; however, a majority of the non-survivors have been admitted to ICU, 23(79.3%) and 26 (89.6%) needed invasive mechanical ventilation; in comparison to survived patients also had a shorter duration of hospital stay (5.5±5.1 versus 8.4±6.1days). Non–survivors more probably suffer from high blood pressure [23 (79.3%) patients versus 80 (61%) patients] and chronic kidney disease [20 (69%) patients versus 9 (6.9%) patients; P<0.001]. Glycated hemoglobin (HbA1c) of more than 9%, and high fasting blood sugar, severe inflammatory response, hepatic, renal, and coagulation impairment was higher in non–survived than those who survived. Conclusion: Multifactorial parameters result in the poor prognosis in diabetic patients; therefore, it is critical for identifying the key clinical, as well as laboratory characteristics of COVID-19 cases that lead to severe disease and increase the risk of death.

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Comparing the Suicidal Ideation in Diabetic Patients Receiving Insulin with Oral Medication

Iranian journal of diabetes and obesity ◽

10.18502/ijdo.v11i3.2604 ◽

2020 ◽

Author(s):

Mahboube Ahmad Nazari ◽

Hamid Oliaee ◽

Reza Bidaki ◽

Mohammad Hossein Sorbi

Keyword(s):

Suicidal Ideation ◽

Significant Relationship ◽

Cross Sectional Study ◽

P Value ◽

Diabetic Patients ◽

Sectional Study ◽

Cross Sectional ◽

Medication Treatment ◽

Patients With Diabetes ◽

Suicidal Ideation Questionnaire

Objective: Diabetes is one of the chronic diseases which can be accompanied with suicide. The study was conducted to assess and compare the prevalence of suicidal ideation in diabetic patients receiving insulin and oralmedication treatment. Materials and Methods: In this cross-sectional study, 2000 patients with diabetes supported by diabetes institute of Rafsanjan in 2017. After giving conscious permission, the patients filled in a demographic checklist and Beck suicidal ideation questionnaire. The data were analyzed using SPSS-16. Results: Prevalence of suicidal ideation in patients with diabetes receiving insulin was 3.2% (n=32) and in people receivingoral medication treatment was 3.1% (n=31). There were no association between suicidal ideation and the method of diabetes treatment. Suicidal ideation was more prevalent in illiterate people; however, no significant relationship was seen between suicidal ideation and education level. Also, there was no significant relationship between marital status and suicidal ideation. There was no relationship between suicidal thoughts and the method of treatment ( P -value: 0.05). Conclusion: Suicidal ideation is more prevalent in diabetic patients, but there were not differences between two group under insulin therapy and oral anti-diabetic agents.

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Occupational stress and its related demographic factors among Iranian CCU nurses: a cross-sectional study

BMC Research Notes ◽

10.1186/s13104-019-4674-5 ◽

2019 ◽

Vol 12 (1) ◽

Cited By ~ 2

Author(s):

Azam Faraji ◽

Mahtab Karimi ◽

Seyyed Mohsen Azizi ◽

Maryam Janatolmakan ◽

Alireza Khatony

Keyword(s):

Occupational Stress ◽

Demographic Factors ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Academic Degree ◽

Significant Difference ◽

The Mean ◽

And Performance ◽

High Level

Abstract Objectives Occupational stress can have an adverse effect on mental and physical health and performance of nurses. The aim of this study was to investigate the occupational stress of Iranian critical care unit (CCU) nurses and its related demographic factors. Results In this cross-sectional study, 155 CCU nurses were randomly selected. The Osipow Occupational Stress Questionnaire was used as data collection tool. The mean of nurses’ occupational stress was 210.13 ± 40.87 out of 300, which was at the “moderate-to-high” level. The highest mean of occupational stress was related to the subscale of “Role Overload” (36.30 ± 6.98) and the lowest mean was related to the subscale of “Physical Environment” (33.58 ± 9.76). There was no statistically significant difference between the mean occupational stress and variables of sex, age, academic degree and working experience.

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Electrolyte Imbalance in Admitted Diabetic Patients: Patterns and Factors Responsible- A Cross Sectional Study

KYAMC Journal ◽

10.3329/kyamcj.v5i1.32317 ◽

2017 ◽

Vol 5 (1) ◽

pp. 458-466

Author(s):

Sheikh Salahuddin Ahmed ◽

Fazle Nur ◽

Md Rahamat Ullah ◽

Abdullah Al Mamun ◽

Tarafdar Runa Laila ◽

...

Keyword(s):

Cross Sectional Study ◽

Health Care Facilities ◽

Electrolyte Imbalance ◽

Diabetic Patients ◽

Cross Sectional ◽

Metabolic Complications ◽

Electrolyte Disturbances ◽

Patients With Diabetes ◽

Rational Management ◽

Collection Form

Diabetes Mellitus (DM) is a major burden upon health-care facilities in all countries. Electrolyte imbalances (EI) are very common in admitted patients with diabetes which leads to substantial morbidity and mortality. Every patient with diabetes needs thorough evaluation for the etiology and precipitating factors responsible for EI and therefore rational management. Data regarding the incidence of EI in DM in our country is limited. There is no existing record for profiling of EI in Bangladeshi diabetic subjects. The objective of this study was to find out the common types of EI in hospitalized diabetic patients and to determine the influencing factors responsible for them. Samples were selected from all adult nonpregnant diabetic patients admitted in the indoor, department of Medicine with electrolyte disturbances irrespective of their cause of admission. A total number of 150 admitted diabetic patients with electrolyte imbalance were interviewed, examined physically and laboratory specimen taken for biochemical analysis. Information was collected in a semi structured data collection form for analysis. Hyponatremia was found to be the most common EI in admitted diabetic patients. Electrolyte imbalance was found to be more common in the aged and female populations. Common factors influencing EI were vomiting, diarrhea, sweating, uncontrolled diabetes with severe hyperglycemia and certain drugs especially diuretics. Among the other well established complications of diabetes like acute metabolic complications, microangiopathy and macroangiopathy, EI should also be considered especially in the admitted patients.KYAMC Journal Vol. 5, No.-1, Jul 2014, Page 458-466

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