scholarly journals Pengaruh Pemberian Tepung Tempe terhadap Kadar Kolesterol Total Darah Mencit (Mus musculus) Hiperkolesterol

bionature ◽  
2019 ◽  
Vol 20 (2) ◽  
pp. 116
Author(s):  
Heryl Rumtal ◽  
Rosdiana Ngitung ◽  
A. Mu’nisa A. Mu’nisa
Keyword(s):  
Mus Musculus ◽  
Blood Cholesterol ◽  
Cholesterol Concentration ◽  
Total Blood ◽  
Treatment Groups ◽  
Independent Variable ◽  
The Subject ◽  
Imprinting Control Region ◽  
Total Blood Cholesterol ◽  
Research Show

Abstract. This research is experimental which aims to determine the effect of giving Tempe Flour to total blood cholesterol concentration of hypercholesterol mice (Mus musculus). The independent variable of this research Tempe Flour while the dependent variable is the total blood cholesterol concentration of mice (Mus musculus). The subject of this research is 25 male ICR strain (Imprinting Control Region) mice with 3 months age divided 5 treatment groups which are normal group, hypercholesterol group, giving of tempe flour at dose of 10 g / day / BB (P1), 20 g / days / BB (P2) and 25 g / day / BB (P3). Tempe flour is given after the giving of cholesterol feed. All mices blood cholesterol concentration were check after the time of treatment. The result is analyz by using ANOVA with Ducan test. The result of this research show that the giving of Tempe Flour affected the decrease of blood cholesterol concentration of mice (Mus musculus) in dose of 10 g/day/BB,20 g/day/BB and 25 g/day/BB. Dose of 25 g/day/BB showed an effective dose for lowering cholesterol in the research.   Keywords: tempe flour, cholesterol, hypercholesterol, mencit (Mus musculus)

scholarly journals Effect Of Pomegranate (Punica granatum L.) Fraction In Reducing Total Blood Cholesterol Levels and Triglyceride in Mice (Mus muscullus L.)

2020 ◽  
Vol 4 (1) ◽  
pp. 14-22
Author(s):  
Nurlaily Agustini ◽  
Arum Setiawan ◽  
Salni Salni
Keyword(s):  
Punica Granatum ◽  
Positive Control ◽  
Negative Control ◽  
Blood Cholesterol ◽  
Total Blood ◽  
Methanol Fraction ◽  
Treatment Groups ◽  
Cholesterol Levels ◽  
Punica Granatum L ◽  
Total Blood Cholesterol

Pomegranate (Punica granatum L.) will be examined by looking at the ability between pomegranate extracts or fractions, which are more effective in lowering total blood cholesterol and triglyceride levels in mice. This study aims to determine the active pomegranate fraction that can reduce the total cholesterol levels and triglyceride in mice. The research method used was an experimental method with a Completely Randomized Design (CRD) which was divided into 6 treatment groups, and test animals divided into 6 treatment groups namely negative control given aquades, positive control fed a high-fat diet, given simvastatin, given 25 mg/grBB of pomegranate methanol fraction, given 50 mg/grBB of pomegranate methanol fraction, given 100 mg/grBB of pomegranate methanol fraction, each treatment group will be divided into 4 male mice.Based on the results of this study that the active fraction that has an effect in reducing blood cholesterol levels and mice triglycerides is the treatment given 100mg/grBB of pomegranate water methanol fraction.

scholarly journals EXPLORATION OF RBC AND HGB IN MENCIT (Mus musculus) HYPEROLOLERINOLEMIA

2013 ◽  
Vol 1 (2) ◽  
pp. 126
Author(s):  
Nofisulastri Nofisulastri ◽  
Baiq Mirawati
Keyword(s):  
Mus Musculus ◽  
Block Design ◽  
Positive Control ◽  
Blood Cholesterol ◽  
Negative Group ◽  
Total Blood ◽  
Randomized Block Design ◽  
Ad Libitum ◽  
Total Blood Cholesterol ◽  
Clear Information

So far there is no clear information about RBC and HGB linkage with hypercholesterolemia, especially for arteriosclerosis and hypertension patient. In the future, this research is expected to add a repertoire of knowledge and people knew about hypercholesterolemia and the utilization of appropriate alternative medicine. A total of 20 mice (Mus musculus) age ± 2 months of hypercholesterolemia caused by cholesterol-rich diet (ad libitum). The data were analyzed by analysis of variance based on Randomized Block Design (RAK) 1% with 5 (five) groups and 4 replications (positive control, negative group, and the group of celery extract dose 0,5 ml with concentration 25%, 50%, 100%). It was concluded that HGB in line with RCB (either treated with celery extract or mice treated with hypercholesterolemia) and the provision of celery extract significantly did not affect RBC and HGB with total blood cholesterol level of mencit.

The effects of dyslipidemia on noise-induced hearing loss in a petrochemical workers in the Southwest of Iran

Work ◽  
2021 ◽  
pp. 1-8
Author(s):  
Payam Rashnoudi ◽  
Arman Amiri ◽  
Maryam Omidi ◽  
Abbas Mohammadi
Keyword(s):  
Hearing Loss ◽  
Cross Sectional Study ◽  
Blood Cholesterol ◽  
Noise Induced Hearing Loss ◽  
Total Blood ◽  
Cross Sectional ◽  
Inner Diameter ◽  
Spss Software ◽  
Southwest Of Iran ◽  
Total Blood Cholesterol

BACKGROUND: Research has shown that the decrease in the inner diameter of vessels caused by hyperlipidemia lowers the capacity for blood oxygen delivery to the cochlea. This leads to impaired cochlear metabolism and causes hearing problems. OBJECTIVE: The effects of dyslipidemia on noise-induced hearing loss in workers were examined. METHODS: This descriptive cross-sectional study was performed on 692 male employees in a petrochemical industry in the southwest of Iran exposed to 85 dB noise. Clinical audiometry and blood sample tests were used to evaluate the hearing and prevalence indices of dyslipidemia (cholesterol, triglyceride, HDL and LDL). The data were analyzed using SPSS software version 25 (p = 0.05). RESULTS: The results showed that the prevalence of dyslipidemia was 24.5%with abnormal relative triglyceride frequency of 49.5%, HDL of 28%, LDL of 33%, and total blood cholesterol level of 37.8%. There was no significant relationship between NIHL and dyslipidemia (p >  0.09). However, the major NIHL drops at different frequencies were in the individuals with dyslipidemia. The parameters age and dyslipidemia increased NIHL odds ratio (95%C.I.). by 1.130 (1.160–1.100) and 1.618 (2.418–1.082) respectively CONCLUSION: The rate of hearing loss in individuals with dyslipidemia increases at different frequencies and it leads to an increase of the OR of NIHL in individuals with dyslipidemia. We can control dyslipidemia and its effective factors. The NIHL is more common in people exposed to noise.

scholarly journals Pengaruh Pemberian Alpukat Terhadap Kadar Kolesterol Total Darah Pada Mahasiswa/i Obesitas Di Fakultas Kedokteran Universitas HKBP Nommensen Medan Tahun 2019

2021 ◽  
Vol 6 (2) ◽  
pp. 40-43
Author(s):  
Syupiarni Putri Waruwu ◽  
Joseph Partogi Sibarani ◽  
Saharnauli Janna Verawaty Simorangkir
Keyword(s):  
Total Cholesterol ◽  
Cholesterol Level ◽  
Density Lipoprotein ◽  
The Body ◽  
Blood Cholesterol ◽  
Ldl Oxidation ◽  
Blood Cholesterol Level ◽  
Total Blood ◽  
Cholesterol Levels ◽  
Total Blood Cholesterol

Background: Cholesterol is a fat that does not dissolve easily in the blood. Most of the cholesterol in the blood is attached to specific protein carriers in the plasma in the form of lipoprotein complexes, which are soluble in water. Lipoprotein which carries cholesterol throughout the body. namely LDL (Low Density Lipoprotein) and HDL (High Density Lipoprotein). An increase in LDL in the body tends to form atherosclerosis. In contrast HDL cholesterol inhibits LDL oxidation so that atherosclerotic plaque formation does not occur. Obesity is one of the risk factors for atherosclerosis with manifestations of coronary heart disease. Handling of obesity has been done by many researchers and implemented. One ingredient from nature that serves as an alternative ingredient to lower blood cholesterol levels is avocado. Objective: To determine the effect of avocado administration on total blood cholesterol levels in the obese college students at the Medical Faculty of Nommensen HKBP University in 2019. Methods :This research is a pre-experimental study with a pre-post test design in one group. The sample was selected by purposive sampling method and obtained 20 obese students. Subjects consumed avocado juice every day for 14 days. Total cholesterol levels were measured before (day 0) and after (day 14) treatment. Results: The mean total cholesterol level of the subject's blood on the pretest examination was 188.10 mg / dL and the posttest examination was 180.05 mg / dL. There was a decrease in the average total blood cholesterol level of 8.05 mg / dl. Paired T-test showed that there was a non-significant decrease in mean total blood cholesterol level with a value of p = 0.068 (p <0.05). Conclusion: In this study there was no effect of avocado administration on total blood cholesterol levels in obese students.

Abstract 29: Loss of Ideal Total Cholesterol Early in Life: The National Health and Nutrition Examination Survey (NHANES)

Circulation ◽  
2015 ◽  
Vol 131 (suppl_1) ◽  
Author(s):  
Joseph C Engeda ◽  
Katelyn M Holliday ◽  
Shakia T Hardy ◽  
Sujatro Chakladar ◽  
Gerardo Heiss ◽  
...  
Keyword(s):  
American Heart ◽  
Transition Probabilities ◽  
Heart Association ◽  
Blood Cholesterol ◽  
Total Blood ◽  
Cross Sectional ◽  
Demographic Groups ◽  
Health And Nutrition ◽  
One Year ◽  
Total Blood Cholesterol

Introduction: Ideal total blood cholesterol (TC) levels are associated with lower cardiovascular disease (CVD) morbidity and mortality. In the U.S. TC increases up to middle age, but declines at older ages. Few studies have characterized the transition from ideal to intermediate and poor TC levels in different life epochs and in minorities. Methods: Cross-sectional 2007-2012 NHANES data (N = 11,140) were used to estimate the age-, race-, and sex- specific prevalence of ideal (≥20 years: <200 mg/dL untreated, 16-19 years: <170 mg/dL), intermediate (≥20 years: 200-239 mg/dL or treated to goal, 16-19 years: 170-199 mg/dL), and poor (≥20 years: ≥240 mg/dL, 16-19 years: ≥200 mg/dL) TC, defined per American Heart Association criteria. We then used these data and novel Markov-type models to estimate net transition probabilities between ideal, intermediate and poor TC. Results: Between the ages of 16 and 18, the prevalence of ideal TC among European American (EA) and African American (AA) men was approximately 68%, notably higher than the prevalence in EA women (63%) and AA women (61%). Variation in the loss of ideal TC was also observed by race and sex. Between 16-50 years of age, the proportion of AA men, EA men and EA women with ideal levels of TC declined approximately 2.0% (95% CI: 1.8%, 2.2%) per year. In AA women by contrast, the age-specific decline in ideal TC was not uniform between 16-50 years of age. The proportion of AA women with ideal levels of TC declined 0.7% (95% CI: 0.2%, 1.2%) per year from 16-20 years of age but increased to 2.8% (95% CI: 2.4%, 3.3%) per year by age 50. Among populations with intermediate TC levels, estimated 1-year net transitions to poor TC peaked at age 16, the earliest age under investigation, for EA men, EA women, and AA men but remained stable for AA women through 70 years of age, where a net 0.6% (95% CI: 0.1%, 1.3%) of the population with intermediate TC levels transitioned to poor TC levels one year later. In all demographic groups and life epochs, greater proportions of the population transitioned from intermediate to poor TC than from poor to intermediate TC. Conclusions: Loss of ideal TC begins early in life and shows divergent patters by gender and race. Difficulties re-attaining ideal TC once classified as intermediate or poor support interventions that promote ideal TC levels in younger ages, especially among AA women.

Correlation Between Body Mass Index (BMI) and Fasting Total Blood Cholesterol Level among Undergraduate Students

2016 ◽  
Vol 15 (9) ◽  
pp. 873-877
Author(s):  
Saeid Reza Doustjalal ◽  
Hlaing Thaw Dar ◽  
Khin Thant Zin ◽  
Kumar Raghav Gujjar ◽  
Ratika Sharma ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Cholesterol Level ◽  
Body Mass ◽  
Undergraduate Students ◽  
Blood Cholesterol ◽  
Blood Cholesterol Level ◽  
Total Blood ◽  
Total Blood Cholesterol

Low Affinity - Platelet Factor 4 and Total Blood Cholesterol in Ligraine Patients

Cephalalgia ◽  
1985 ◽  
Vol 5 (3_suppl) ◽  
pp. 404-405
Author(s):  
Wojciech Kozubski ◽  
Jolanta Niewiarowska
Keyword(s):  
Platelet Factor 4 ◽  
Blood Cholesterol ◽  
Total Blood ◽  
Platelet Factor ◽  
Total Blood Cholesterol

Behavior Change at the Worksite: Does Social Support Make a Difference?

1995 ◽  
Vol 10 (2) ◽  
pp. 125-131 ◽  
Author(s):  
James R. Terborg ◽  
Judith Hibbard ◽  
Russell E. Glasgow
Keyword(s):  
Social Support ◽  
Behavior Change ◽  
Dietary Fat ◽  
Disease Risk ◽  
Blood Cholesterol ◽  
Total Blood ◽  
Risk Status ◽  
Support At Work ◽  
Heart Disease Risk ◽  
Total Blood Cholesterol

Purpose. This study examines whether social support for behavior change at work is associated with changes in employee heart disease risk factors. Design. A prospective correlational design was used with data sets collected 12 months apart. Setting. Twenty-five small to medium worksites in Oregon. Subjects. Participants were 689 men and 421 women volunteers who participated in two health assessments at the worksite on company time. Measures. Demographic characteristics, gender, social support, smoking behavior, dietary fat intake, and total blood cholesterol. Results. Employees reporting strong social support at work for not smoking and for limiting dietary fat were less likely to smoke (r = -.11, odds ratio [OR] = .86) and to consume fat in their diets (r = −.10) at baseline. Employees who reported the most change in social support over a 12-month period were most likely to have stopped smoking (r = .15, OR = 1.31). Social support at baseline, however, was unrelated to change in smoking, dietary fat, or total blood cholesterol in a prospective design. Although women reported more social support at work than did men, no differential gender effects of social support were reported on heart disease risk status or change in risk status. Conclusion. Baseline social support at work did not predict future behavior change. The observed association between social support and lifestyle may be better explained as cognitive rationalization than by the impact of social support on behavior.

scholarly journals Uji efek ekstrak biji alpukat (Persea americana Mill.) terhadap kadar kolesterol total pada tikus wistar (Rattus norvegicus)

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Abraham T. Suhendra ◽  
Henoch Awaloei ◽  
Jane Wuisan
Keyword(s):  
Traditional Medicine ◽  
Wistar Rats ◽  
Seed Extract ◽  
Persea Americana ◽  
Blood Cholesterol ◽  
Control Group ◽  
Tropical Country ◽  
Total Blood ◽  
Total Blood Cholesterol ◽  
Avocado Seed

Abstract: Indonesia is a tropical country that has more than 1,000 kinds of medicinal plants. Medicinal plant is the use of part(s) of plants as ingredients in traditional medicine or synthetic drugs. One of the traditional medicine is avocado. Several studies have concluded that the avocado fruit and leaves can reduce total blood cholesterol levels while the seed is used in Nigeria for treating hypertension. This was an experimental study. Samples consisted of 12 male Wistar rats, divided into 4 groups (3 rats in each group). The treated groups were given propylthiouracil (PTU) for 14 days then the rats were given 125 mg/kg or 250 mg/kg of avocado seed extract for 14 days. The positive control group was given PTU 8 mg/rat for 14 days, followed by simvastatin 0.2 mg for 14 days. The negative control group was only given food and water. The results showed that the average level of total blood cholesterol in Wistar rats after treated with 125 mg/kg and 250 mg/kg avocado seed extract decreased by 18.1% and 31.2%, respectively. Conclusion: Avocado seed extract had an effect in reducing total blood cholesterol of Wistar rats.Keywords: avocado seed, total cholesterol levelAbstrak: Indonesia merupakan salah satu negara tropis yang memiliki banyak tumbuhan dimana lebih dari 1000 tumbuhan tersebut dapat digunakan sebagai tanaman obat. Tanaman obat ialah penggunaan bagian dari tanaman atau tumbuhan sebagai bahan dalam pembuatan obat tradisional maupun obat sintetik. Salah satu tanaman yang digunakan sebagai obat tradisional ialah alpukat. Beberapa penelitian mengenai tanaman alpukat menunjukkan bahwa buah dan daun dari tanaman Alpukat dapat menurunkan total kolesterol dalam darah, sedangkan biji alpukat digunakan di Nigeria sebagai pengobatan untuk hipertensi. Penelitian ini menggunakan metode eksperimental. Sampel ialah 12 ekor tikus Wistar jantan yang dibagi menjadi 4 kelompok (setiap kelompok terdiri dari 3 tikus). Kelompok-kelompok perlakuan diberikan propiltiourasil (PTU) selama 14 hari kemudian diberikan 125 mg/kg atau 250 mg/kg ekstrak biji Alpukat selama 14 hari. Kelompok kontrol positif diberikan PTU selama 14 hari kemudian diberikan simvastatin 0,20 mg/kg selama 14 hari. Kelompok kontrol negatif hanya diberikan pakan dan air. Hasil penelitian memperlihatkan rerata kadar kolesterol total tikus Wistar setelah diberikan 125 mg/kg dan 250 mg/kg ekstrak biji alpukat menurun sebesar 18,1% dan 31,2%. Simpulan: Ekstrak biji Alpukat berefek menurunkan kadar kolesterol total pada tikus Wistar.Kata kunci: biji alpukat, kadar kolesterol total

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