scholarly journals UJI PELEPASAN LOGAM KROMIUM (Cr) DAN NIKEL (Ni) BEBERAPA MEREK BRAKET STAINLESS STEEL DALAM CAIRAN SALIVA ARTIFISIAL

e-GIGI ◽  
2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Chealsea J. Siwy ◽  
Lydia E. N. Tendean ◽  
P. S. Anindita
Keyword(s):  
Stainless Steel ◽  
Artificial Saliva ◽  
Saliva Sample ◽  
Corrosion Process ◽  
The Body ◽  
Metal Corrosion ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Nickel Sample

Abstract: Stainless steel bracket, a popular fixed orthodontic appliance containing chromium and nickel, is used most frequently in fixed orthodontic treatment. Stainless steel bracket interacts with oral cavity environment and causes metal corrosion process. The released chromium and nickel due to the corrosion process can get into the body and cause hypersensitivity reactions. This study aimed to determine the release of chromium and nickel from stainless steel bracket in artificial saliva. This was an experimental laboratory study with a quasy experimental and nonequivalent control group design. Samples were analyzed by using spectrophotometry ultraviolet visible (UV-Vis) to determine the releasing of chromium and nickel. There were 4 kinds of stainless steel bracket immersed and stored in artifisial saliva at 37oC for 30 days. The result showed that each sample varied in the release of chromium and nickel from stainless steel brackets in the artificial saliva. Sample A had 0.025 ppm chromium and 0.689 ppm nickel; sample B had 0.002 ppm chromium and 1.012 ppm nickel; sample C had 0.008 ppm chromium and 1.130 ppm nickel; and sample D had 0.027 ppm chromium and 1.176 ppm nickel. The release of nickel of each sample was higher than of chromium. There was no specific pattern of the release of chromium and nickel due to the different composition of stainless steel brackets which depend on the manufacturers.Keywords: stainless steel bracket, chromium, nickel, spectrophotometry UV-Vis, artificial salivaAbstrak: Braket stainless steel sering digunakan dalam perawatan ortodonti cekat yang umumnya mengandung kromium dan nikel. Braket stainless steel akan berinteraksi dengan lingkungan dalam rongga mulut sehingga menyebabkan proses korosi. Pada proses korosi terjadi pelepasan logam kromium dan nikel yang dapat masuk ke dalam tubuh dan dapat mengakibatkan reaksi hipersensitivitas. Penelitian ini bertujuan untuk mengetahui besarnya logam kromium dan nikel yang terlepas dari braket stainless steel dalam cairan saliva artifisial. Penelitian ini menggunakan metode eksperimental laboratorik dengan jenis penelitian pra eksperimental serta desain penelitian nonequivalent control group design. Sampel diuji menggunakan spektrofotometri UV-Vis untuk mengetahui pelepasan logam kromium dan nikel. Sampel terdiri dari 4 macam merek braket direndam dalam larutan saliva artifisial selama 30 hari pada suhu 37oC. Data hasil penelitian diolah menggunakan komputerisasi. Hasil penelitian menunjukkan terdapat pelepasan logam kromium dan nikel dalam saliva artifisial yang bervariasi di tiap sampel. Sampel A memiliki pelepasan kromium 0,025 ppm dan nikel 0,689 ppm; sampel B memiliki pelepasan kromium 0,002 ppm dan nikel 1,012 ppm; sampel C memiliki pelepasan kromium 0,008 ppm dan nikel 1,130 ppm; dan sampel D memiliki pelepasan kromium 0,027 ppm dan nikel 1,176 ppm. Pelepasan nikel pada tiap sampel lebih tinggi dibandingkan dengan pelepasan kromium. Hasil penelitian tidak menunjukan pola tertentu, hal ini dapat disebabkan karena komposisi yang berbeda-beda dari braket stainless steel tergantung ketentuan masing-masing pabrik pembuatnya.Kata kunci: braket stainless steel, kromium dan nikel, spektrofotometri UV-Vis, saliva artifisial

scholarly journals Perbedaan Pelepasan Ion Nikel (Ni) dan Kromium (Cr) Kawat Ortodonti Stainless Steel pada Perendaman Pasta Gigi Ortodonti dan Non-Ortodonti

e-GIGI ◽  
2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Loisaviny H. D. Wondal ◽  
P. S. Anindita ◽  
Elita Tambunan
Keyword(s):  
Stainless Steel ◽  
Citric Acid ◽  
Artificial Saliva ◽  
Control Group ◽  
Control Group Design ◽  
Chromium Ion ◽  
Group Design ◽  
Chromium Ions ◽  
Post Test ◽  
Orthodontic Archwires

Abstract: Recently, orthodontic toothpaste with colostrum has been introduced which is different from non-orthodontic toothpaste. Albeit, orthodontic and non-orthodontic toothpastes contain citric acid and some kinds of sodium compounds that can initiate corrosion of stainless steel orthodontic archwire indicated by the release of nickel and chromium ions. This study was aimed to determine the difference in nickel and chromium ion releases from the stainless steel orthodontic archwires immersed in artificial saliva plus orthodontic toothpaste or non-orthodontic toothpaste. This was a true experimental study with a post-test only control group design. Samples were stainless steel orthodontic archwires immersed in artificial saliva plus orthodontic toothpaste or non-orthodontic toothpaste. Released nickel and chromium ions were analyzed with atomic absorption spectrometer (AAS). In both treatment groups (orthodontic and non-orthodontic pastes), the independent t-test showed that the P value of released nickel ions was 0.572 and of released chromium ions was 0.059 (P >0.05). Conclusion: There were no significant differences between the release of nickel and chromium ions of stainless steel orthodontic archwires immersed in artificial saliva plus orthodontic toothpaste and in artificial saliva plus non-orthodontic toothpaste.Keywords: stainless steel orthodontic archwire, nickel and chromium ion, orthodontic and non-orthodontic toothpaste. Abstrak: Dewasa ini sudah tersedia pasta gigi ortodonti dengan kandungan colostrum yang membedakannya dengan pasta gigi non-ortodonti. Pasta gigi ortodonti dan non-ortodonti mengandung citric acid dan beberapa jenis senyawa sodium yang dapat memicu terjadinya korosi pada kawat ortodonti stainless steel yang ditandai dengan pelepasan ion nikel dan kromium. Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan jumlah pelepasan ion nikel dan kromium kawat ortodonti stainless steel yang direndam dalam pasta gigi ortodonti dan non-ortodonti. Jenis penelitian ialah eksperimental murni dengan post-test only control group design. Sampel yang digunakan yaitu kawat ortodonti stainless steel yang direndam dalam saliva artifisial ditambahkan pasta gigi ortodonti atau yang non-ortodonti. Pelepasan ion nikel dan kromium dianalisis menggunakan Spektrometri Serapan Atom (SSA). Hasil uji t tidak berpasangan pada kelompok perlakuan baik larutan pasta gigi ortodonti maupun yang non-ortodonti menunjukkan pelepasan ion nikel dengan P=0,572 dan pelepasan ion kromium dengan P=0,059 (P >0,05). Simpulan: Tidak terdapat perbedaan bermakna pelepasan ion nikel dan kromium pada kawat ortodonti stainless steel yang direndam dalam saliva artifisial ditambahkan pasta gigi ortodonti dibandingkan pasta non ortodonti.Kata kunci: kawat ortodonti stainless steel, nikel, kromium, pasta gigi ortodonti dan non ortodonti

scholarly journals Efektivitas Ekstrak Bawang Merah (Allium ascalonicum L) Terhadap Penurunan Suhu Tubuh Anak dengan Demam Pasca Imunisasi DPT Pentabio

2021 ◽  
Vol 11 (1) ◽  
pp. 6
Author(s):  
Setiawandari Setiawandari ◽  
Eka Deviany Widyawaty
Keyword(s):  
Body Temperature ◽  
Hepatitis B ◽  
The Body ◽  
Control Group ◽  
P Value ◽  
Type B ◽  
Control Group Design ◽  
Group Design ◽  
Influenza Type ◽  
Post Test

The immunizations that must be given to children include the Diphtheria Pertussis Tetatus-Hepatitis B-Hemophilus Influenza type B vaccine or better known as Pentabio DPT. The DTwP / HB / HiB vaccine is given to babies in 3 doses at 1 month intervals. This immunization caused a systemic reaction, one of which was a fever of 0.85% in the first 30 minutes and increased to 14.03% on the day after immunization. The purpose of this study was to determine the effectiveness of shallots (Allium ascalonicum L) in reducing the body temperature of feverish children after Pentabio DPT immunization. This type of research was quasi-experimental study, with pre and post test with control group design. The sample in this study were babies who received DPT immunization as many as 20 respondents. DPT Pentabio immunization was given a dose of 0.5 ml in the intervention group and the control group. The statistical test used was the T test. The results showed that there was a significant effect of shallots on in reducing the body temperature of feverish children after Pentabio DPT immunization, with a p-value of 0.000. Keywords: shallots; body temperature; fever; Pentabio DPT immunization ABSTRAK Imunisasi yang wajib diberikan kepada anak-anak diantaranya adalah vaksin Diphtheria Pertusis Tetatus-Hepatitis B-Hemophilus Influenza type B atau lebih dikenal dengan DPT Pentabio. Vaksin DTwP/HB/HiB diberikan kepada bayi sebanyak 3 dosis dengan interval 1 bulan. Imunisasi ini menimbulkan reaksi sistemik salah satunya berupa demam 0,85% pada 30 menit pertama dan meningkat menjadi 14,03% pada satu hari pasca imunisasi. Tujuan dari penelitian ini adalah mengetahui efektifitas bawang merah (Allium ascalonicum L) terhadap penurunan suhu tubuh anak demam pasca imunisasi DPT Pentabio. Jenis penelitian quasi eksperimen dengan pre and post test with control group design. Sampel pada penelitian ini adalah bayi yang mendapat imunisasi DPT sebanyak 20 orang responden. Pemberian imunisasi DPT PENTABIO Pentabio dosis 0,5 ml pada kelompok intervensi dan kelompok kontrol. Uji statistik yang digunakan adalah Uji T. Hasil penelitian menunjukkan ada pengaruh yang signifikan dari bawang merah dalam menurunkan suhu tubuh anak demam pasca imunisasi DPT Pentabio, dengan p-value 0,000. Kata kunci: bawang merah; suhu tubuh; demam; imunisasi DPT Pentabio

scholarly journals PENGARUH DESINFEKSI CETAKAN FISIOLOGIS DENGAN MICROWAVE DAN SODIUM HIPOKLORIT TERHADAP JUMLAH CANDIDA ALBICANS DAN STABILITAS DIMENSI MODEL KERJA GIGI TIRUAN CEKAT

2019 ◽  
Vol 12 (3) ◽  
pp. 322-328
Author(s):  
Putri Welda Utami Ritonga ◽  
Bayu Panca Nugraha
Keyword(s):  
Stainless Steel ◽  
Candida Albicans ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test

Bahan cetak polivinil siloksan(PVS) sering digunakan pada pencetakan untuk pembuatan gigi tiruan cekatkarena mampu menghasilkan cetakan yang akurat dengan dimensi cetakan yang stabil serta dapat disimpan dalam waktu lama. Namun, pencetakan ini tidak terlepas dengan hubungannya terhadap rongga mulut dan mikroorganismenya yang dapat menimbulkan infeksi silang.Candida albicansmerupakan jenis mikroorganisme yang sering ditemukan melekat pada permukaan cetakan. Pemilihan cara desinfeksi penting dalam memperoleh keberhasilan desinfeksi Candida albicansserta mempertahankan stabilitas dimensi hasil cetakan. Penelitian ini bertujuan untuk mengetahui pengaruh desinfeksi cetakan fisiologis dengan microwave dan sodium hipoklorit terhadap jumlah Candida albicansdan stabilitas dimensi model kerja gigi tiruan cekat. Penelitian ini dilakukan pada sampel berupa cetakan yang didapat dari pencetakan model induk yang terbuat dari stainless steel berbentuk silindris dengan tinggi 3 mm dan diameter 29,97 mm serta memiliki 3 takik horizontal dengan jarak 2,5 mm dan 2 takik vertikal dengan jarak 25,02 mm dengan kedalaman 500 μm untuk uji jumlah Candida albicans, dan model kerja yang didapat dari pengisian cetakan dengan bahan gips keras tipe IV untuk uji stabilitas dimensi. Rancangan penelitian adalah eksperimental laboratoris dengan post test only control group design.30 sampel hasil cetakan PVS digunakan untuk menghitung jumlah Candida albicansdan 30 sampel model kerja terbuat dari gips tipe IV digunakan untuk pengukuran stabilitas dimensi. Data yang diperoleh dianalisis dengan uji Kruskal-Wallis. Hasil penelitian menunjukkan ada pengaruh desinfeksi cetakan fisiologis dengan microwavedan sodium hipoklorit terhadap jumlah Candida albicansdan stabilitas dimensi model kerja.

scholarly journals JUMLAH ION KROMIUM (Cr) DAN NIKEL (Ni) KAWAT ORTODONTIK STAINLESS STEEL YANG TERLEPAS DALAM PERENDAMAN SALIVA

e-GIGI ◽  
2015 ◽  
Vol 3 (2) ◽  
Author(s):  
Ciendy O. Jura ◽  
Lydia E. N. Tendean ◽  
P. S. Anindita
Keyword(s):  
Stainless Steel ◽  
Oral Cavity ◽  
Artificial Saliva ◽  
Steel Wire ◽  
Stainless Steel Wire ◽  
Control Group ◽  
Ion Release ◽  
Control Group Design ◽  
Orthodontic Wire ◽  
Experimental Laboratory

Abstract: Orthodontic stainless steel wire is one of the instrument components oftenly used in orthodontic treatment and may persist in the oral cavity for a long period of time. Orthodontic stainless steelwire in the oral cavity can be corrosive in the presence of Cr and Ni ion release which can be harmful to the human body and the stainless steel wire itself. This study aimed to determine the amount of Cr and Ni ions released from the stainless steel orthodontic wire that was immersed in artificial saliva. This was an experimental laboratory study with a posttest only control group design. Samples were analyzed by using a UV-Vis spectrophotometry to determine the released Cr and Ni ions in the saliva. Samples consisted of 4 brands of orthodontic stainless steel wires immersed in artificial saliva for 30 days with a temperature of 370C. Data were analyzed by using a computer program. The results showed that the release of Cr ions in samples A, B, C, and D respectively were: 0.302 ppm, 0.331ppm, 0,311 ppm, and 0.483 ppm meanwhile of Ni ions were 1.930 ppm, 1.778 ppm, 1.654 ppm, and 1.391ppm. Conclusion: The release of Cr and Ni ions varied in each sample of orthodontic stainless steel wire .Keywords: orthodontic stainless steel, Cr, Ni, artificial saliva, UV-Vis spectrophotometryAbstrak: Kawat ortodontik stainless steel merupakan salah satu komponen alat yang sering digunakan dalam perawatan ortodontik dan dapat bertahan dalam rongga mulut untuk jangka waktu yang lama. Kawat ortodontik stainless steel yang berada di dalam rongga mulut dapat mengalami korosi dengan adanya pelepasan ion Cr dan Ni yang bersifat merugikan bagi tubuh manusia dan kawat ortodontik itu sendiri. Penelitian ini bertujuan untuk mengetahui besarnya jumlah pelepasan ion Cr dan Ni dari kawat ortodontik stainless steel yang direndam dalam saliva buatan. Penelitian ini menggunakan metode eksperimental laboratorium dengan rancangan posttest only control group. Sampel diuji dengan menggunakan spektrofotometri UV-Vis untuk mengetahui pelepasan ion Cr dan Ni dalam saliva. Sampel terdiri dari 4 merek kawat ortodontik stainless steel direndam dalam saliva buatan selama 30 hari dengan suhu 370C. Data hasil penelitian dianalisis menggunakan program komputer. Hasil penelitian menunjukkan pelepasan ion Cr pada sampel A, B, C, dan D berturut-turut 0,302 ppm; 0,331 ppm; 0,311 ppm; dan 0,483 ppm sedangkan pelepasan ion Ni 1,930 ppm; 1,778 ppm; 1,654 ppm; dan 1,391 ppm. Simpulan: Pelepasan ion Cr dan Ni bervariasi dari masing-masing sampel kawat ortodontik stainless steel.Kata kunci : Kawat ortodontik stainless steel, Cr, Ni, saliva buatan, spektrofotometri UV-Vis

scholarly journals Pengaruh pemberian vitamin E terhadap kadar neutrofil setelah latihan fisik

2016 ◽  
Vol 4 (2) ◽  
Author(s):  
Kristo Warong ◽  
Damajanty H.C. Pangemanan ◽  
Joice N.A. Engka
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Physical Exercise ◽  
Tissue Injury ◽  
The Body ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Post Test ◽  
Test Control

Absract: Physical exercise can improve and maintain physical fitness. However, physical exercise can lead to oxidative stress that can reduce the activity of antioxidants. Vitamin E is a fat-soluble antioxidant that could free radicals in the body. Neutrophils play an active role in the process of phagocytosis of bacteria and other microorganisms the damaged tissue caused by tissue injury. This study was aimed to obtain the effect of vitamin E on neutrophil count after physical exercise. This was a field experimental study with a pre post test control group design. Data were analyzed with the Mann Whitney U (α = 0.05). The physical exercise was playing futsal for 60 minutes. Respondents were 30 male respondents divided into 2 groups: treatment and control groups. The levels of neutrophils were examined after physical exercise and after the administration of vitamin E 400 IU for seven days. Data analysis of the effect of vitamin E on neutrophil level after physical exercise showed a p value of 0.031. Conclusion: Vitamin E influenced the levels of neutrophils after physical exercise.Keywords: physical exercise, oxidative stress, vitamin E, neutrophil Abstrak: Latihan fisik merupakan aktivitas yang dilakukan seseorang untuk meningkatkan atau memelihara kebugaran tubuh. Latihan fisik dapat menimbulkan stres oksidatif sehingga dapat menurunkan aktivitas antioksidan. Vitamin E merupakan antioksidan yang larut dalam lemak dan berfungsi untuk mengurangi radikal bebas yang terdapat dalam tubuh. Neutrofil berperan aktif dalam proses fagositosis bakteri, mikroorganisme, dan membersihkan sisa jaringan rusak yang disebabkan oleh cedera jaringan. Penelitian ini bertujuan untuk mengetahui pengaruh vitamin E terhadap kadar neutrofil setelah latihan fisik. Jenis penelitian ialah eksperimental lapangan dengan pre post test control group design. Untuk menguji signifikansi penelitian digunakan uji Mann Whitney U (α = 0,05). Latihan fisik berupa olahraga futsal selama 60 menit dilakukan oleh 30 responden laki-laki yang dibagi dalam 2 kelompok yaitu perlakuan dan kontrol. Kadar neutrofil diukur setelah latihan fisik dan setelah pemberian vitamin E 400 IU selama 7 hari. Hasil statistik menunjukkan terdapat pengaruh bermakna dari vitamin E pada kelompok perlakuan (p=0,031). Simpulan: Terdapat pengaruh vitamin E terhadap kadar neutrofil setelah latihan fisik. Kata kunci: latihan fisik, stres oksidatif, vitamin E, neutrofil

scholarly journals JUMLAH KOLONI CANDIDA ALBICANS PADA PLAT RESIN AKRILIK HEAT CURED SETELAH DILAKUKAN PERENDAMAN EKSTRAK DAUN KEMANGI (OCIMUM BASSILICUM LINN) 50%

2020 ◽  
Vol 16 (2) ◽  
pp. 61-63
Author(s):  
Kadek Ayu Wirayuni ◽  
◽  
Sintha Nugrahini
Keyword(s):  
Candida Albicans ◽  
Leaf Extract ◽  
Acrylic Resin ◽  
The Body ◽  
Control Group ◽  
Control Group Design ◽  
Denture Stomatitis ◽  
Parametric Test ◽  
Group Design ◽  
Cleaning Methods

Accumulation of plaque and food scraps on an acrylic resin base will increase bacterial colonies and C. albicans which will cause denture stomatitis. Maintenance of denture hygiene using mechanical, chemical and combination of two methods. Basil leaf extract contain essential oils which are important in fight against resistant C. albicans biofilms. The purpose of this study was to determine the comparison of C. albicans colonies after cleaning various denture cleaning methods. The method of this study is used an experimental method, the study design is posttest only with control group design. Sample size of heat-cured acrylic resin plate is 40x12x3mm. this study use Kruskall-Wallis test and Mann-Whitney test as data analysis for comparison tests between groups (non-parametric test). The results showed that there were significant differences between the various cleansing methods used in reducing C. albicans colonies. The compotition of flavonoids basil leaf extract is anti-microbial which can prevent the entry of fungi that harm the body.

scholarly journals Pengaruh Latihan Renang Teratur dan Latihan Renang Tidak Teratur Terhadap Kadar Trigliserida Plasma pada Rattus norvegicus

2018 ◽  
Vol 2 (1) ◽  
pp. 24-40
Author(s):  
Adi Wijayanto
Keyword(s):  
Rattus Norvegicus ◽  
Exercise Program ◽  
The Body ◽  
Control Group ◽  
Regular Exercise ◽  
Control Group Design ◽  
Group Design ◽  
Significant Difference ◽  
Post Test ◽  
And Control

Triglycerides are source of energy in the body, but triglyceride deposits that exceed the threshold will cause health problems, so triglycerides should be lowered to normal. The reduction of triglycerides can be done through physical activity, therefore this study aims to reveal the effect of regular swimming exercises and irregular exercises against triglyceride levels. This research is an experimental research using The Post Test Only Control Group Design design. Subjects of the study were male of Rattus Norvegicus Wistar, 39 subjects was divided into 3 groups with Matched Subject Design technique, which consisted of 2 groups of treatment that is regular and irregular group, and control group. The exercise program was given a swimming with a 3% weight of body weight and was tied 5 cm from the tip of the tail which was performed 3 times per week consistently for regular exercise and 0 to 5 times per week inconsistently for irregular exercise for 12 weeks, While the control group was not given training. In the last week before the blood was taken, the first three groups were given swimming treatment exercises. Based on the results of the anava test, there was a significant difference in the reduction of triglyceride levels among white mice who were given regular exercise with irregular exercise. These results suggest that regular exercise has a better impact on triglyceride reduction than irregular exercise, due to the higher adaptation process of regular exercise.

THEEFFECTS OF CURCUMA RHIZOME EXTRACT (Curcuma xanthorrhiza Roxb.)TREATMENT USING VARIOUS DOSES TOWARDS ENDOMETRIAL THICKNESSIN MICE (Mus musculus) TREATED WITH MONOSODIUM GLUTAMATE (MSG)

2017 ◽  
Vol 2 (1) ◽  
pp. 39
Author(s):  
Fidia Rizkiah Inayatilah
Keyword(s):  
Oxidative Stress ◽  
Free Radicals ◽  
Endometrial Thickness ◽  
Monosodium Glutamate ◽  
The Body ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Curcuma Xanthorrhiza ◽  
One Way Anova

<p><em>Monosodium Glutamate </em>(MSG) is a food seasoning that is widely used. Consumption of MSG in excessive doses can cause an excess of free radicals in the body that trigger oxidative stress and finally affect the reproductive system hormones. These free radicals can be suppressed by administration of antioxidants. Rhizomes of Curcuma xanthorrhiza extracts containantioxidants and they are widely grown. Theyare used as traditional medicine in Indonesia. This experiment was conducted to investigatewhether rhizomes of Curcuma xanthorrhiza extracts areable to inhibit decreasing endometrial thickness in female mice after receiving orally MSG-treatment.This research adoptedtrue experimental posttest only control group design<em>. </em>It includes 25 mice that were divided into 5 groups: control K1 (CMC) and K2 (MSG), treatment group (MSG and rhizomes of Curcuma xanthorrhiza extracts with dose of 0,4 mg/gBW, 0,8 mg/gBW, 1,2 mg/gBW).In addition, the mice’s endometrium were removed to be subsequently stained using Hematoxillin-Eosin. Thickening of uterus was observed and measured with 40x magnitude using Microphoto Microscope Olympus. Data was analized using One Way ANOVA. The research finally comes with a result showing that there were not any significant differences discovered from the endometrium thickening from the five tested groups (p&gt;0,05). Therefore, it is implied that rhizomes of Curcuma xanthorrhiza extracts has no effect on endometrial thickness of uterus by oral MSG-treatment.</p><p> </p><p>Key words: MSG, curcuma, endometrium</p>

scholarly journals Pengaruh Pemberian Glutamin pada Kemampuan Fagositosis Makrofag terhadap Pseudomonas Aeruginosa

2015 ◽  
Vol 4 (3) ◽  
Author(s):  
Daslina Daslina ◽  
Eryati Darwin ◽  
Aziz Djamal
Keyword(s):  
Pseudomonas Aeruginosa ◽  
Immune System ◽  
Amino Acid ◽  
T Test ◽  
The Body ◽  
Control Group ◽  
Control Group Design ◽  
Group Design ◽  
Significant Difference ◽  
Post Test

Abstrak Pseudomonas aeruginosa adalah bakteri penyebab infeksi terbanyak yang resisten terhadap antibiotik. Glutamin adalah asam amino yang terdapat dalam tubuh yang salah satu fungsinya dapat memodulasi imunitas tubuh. Tujuan penelitian ini adalah menentukan potensi glutamin dalam meningkatkan kemampuan sistem imun terhadap infeksi P. aeruginosa. Penelitian eksperimental dengan post test only control group design telah dilakukan terhadap 24 ekor mencit usia 6-8 minggu dengan berat 30 gr. Mencit dibagi ke dalam dua kelompok, yaitu kontrol (K) danperlakuan (P) yang diberi glutamin dengan dosis 30 mg/kg/hari selama 14 hari. Isolasi makrofag peritoneum mencit dilakukan pada hari ke-15 dan dilakukan uji fagositosis menggunakan latex dan bakteri P. aeruginosa. Pengamatan dilakukan terhadap persentase makrofag aktif terhadap latex dan P. aeruginosa. Hasil pengamatan dan analisisstatistik menggunakan metode t-test menunjukkan adanya perbedaan yang signifikan antara kontrol dan perlakuan (p<0.05). Persentase makrofag aktif terhadap latex adalah 0,63 ± 0,058 (K) dan 0,84 ± 0,04 (P), sedangkan terhadap P. aeruginosa adalah 0,56± 0,07 (K) dan 0,80± 0,03 (P). Terlihat bahwa angka persentase fagositosis terhadap P.aeruginosa lebih kecil karena adanya kemampuan bakteri untuk menghadapi makrofag dibandingkan latex. Kesimpulan yang diperoleh dari penelitian ini adalah bahwa asam amino non-esensial glutamin memiliki pengaruh untuk meningkatkan kemampuan sistem imun tubuh. Kata kunci: glutamin, fagositosis makrofag, Pseudomonas aeruginosa Abstract Pseudomonas aeruginosa is the most common cause of bacterial infections that are resistant to antibiotics. Glutamine is an amino acid  in the body that able to modulate the body's immune function. The objective of this study was to determine the potential of glutamine in enhancing the ability of the immune system against infection of P.aeruginosa. Experimental research with post test only control group design was conducted on 24 male minutes 6-8 weeks of age weighing 30 grams. Mice were divided into two groups: control (K) and treatment (P) are given glutamine at a dose of 30 mg / kg / day for 14 days. Isolation of peritoneal macrophages of mice performed on day-15 and testedusing latex and bacterial phagocytosis of P. aeruginosa. Observations were made of the percentage of activated macrophages toward latex and P. aeruginosa. The observation result and statistical analysis using t -test showed a significant difference between the control and treatment (p <0.05). The percentage of active macrophages to latex was0.63 ± 0.058 (K) and 0.84 ± 0.04 (P), while to P. aeruginosa is 0.56 ± 0.07 (K) and 0.80 ± 0.03 (P). That seein it percentage of phagocytosis against P. aeruginosa smaller than compared to latex. Because of the ability of bacteria to confront macrophages. The conclusion from this study is a non-essensial amino acid glutamine has the effect to increase the ability of the body's immune system. Keywords: glutamin, immunity phagocytosis macrophage, Pseudomonas aeruginosa 

scholarly journals EFEKTIVITAS PEPPERMINT DAN POMELO DALAM MENURUNKAN INTENSITAS MUAL DAN MUNTAH PADA IBU HAMIL

2020 ◽  
Vol 6 (4) ◽  
pp. 435-441
Author(s):  
Nora Veri ◽  
Nila Suci Ramadhani ◽  
Alchalidi Alchalidi
Keyword(s):  
Pregnant Women ◽  
The Body ◽  
Nausea And Vomiting ◽  
Control Group ◽  
P Value ◽  
Average Intensity ◽  
Control Group Design ◽  
Group Design ◽  
Significant Difference ◽  
Quasi Experimental

ABSTRACT Background: Emesis gravidarum can get worse into hyperemesis gravidarum which causes the body to become weaker, paler, and the frequency of urination decreases. As a result, decreased body fluids and hemoconcentration of blood can cause tissue damage. Non pharmacological treatment is very important because it reduces the pharmacological effects that appear in pregnant women. The herbal therapy that has been proven to be beneficial is the administration of peppermint, but research on the effects of Pamelo fruit related to nausea and vomiting in pregnant women is still rare.Objective: To determine the comparison of the effectiveness of peppermint and Pomelo orange on the intensity of nausea and vomiting in pregnant womenMethods: The research design was a quasi experimental study with a pretest posttest control group design approach. The number of samples was 24 pregnant women who were grouped into 3 groups.Results: The average intensity of nausea and vomiting in the peppermint group at pretest was 2.38 and decreased at posttest to 1 with P-value 0.004. The intensity of nausea and vomiting in the Pomelo group at pretest was 6.38, falling to 1.75 at posttest with P-value 0.000. The result of further test showed that there was no significant difference in the intensity of nausea and vomiting between the two groups with Sig. 0.428.Conclusion: Peppermint and pomelo are effective in reducing the intensity of nausea and vomiting in trimester I pregnant women.Suggestion : This research needs to be refined by enlarging the research sample and measuring the intensity of nausea and vomiting can be done every day during the study considering that this study only measured twice the number of 24 respondents. Keywords : Nausea, Vomiting, Pregnancy, Peppermint, Pomelo ABSTRAK Latar Belakang : Emesis gravidarum dapat bertambah berat menjadi hiperemesis gravidarum yang mengakibatkan tubuh semakin lemah, pucat, dan frekuensi buang air kecil menurun. Akibatnya cairan tubuh berkurang dan hemokonsentrasi darah yang dapat menimbulkan kerusakan jaringan. Pengobatan non farmakolgis sangat penting karena mengurangi efek farmakologis yang muncul pada ibu hamil. Terapi herbal yang sudah terbukti bermanfaat adalah pemberian peppermint, namun penelitian efek buah Pamelo yang berkaitan dengan mual muntah pada ibu hamil masih jarang.Tujuan Penelitian : Untuk mengetahui  perbandingan efektifitas pemberian peppermint dan Jeruk Pomelo terhadap intensitas  mual dan  muntah pada ibu hamilMetode Penelitian : Rancangan penelitian ini adalah quasi experimental dengan pendekatan pretest posttest control group design. Jumlah sampel  adalah sebanyak 24 orang ibu hamil yang dikelompokkan kedalam 3 kelompok.Hasil Penelitian : Rata-rata intensitas mual muntah pada kelompok peppermint saat pretest adalah 2,38 dan menurun pada saat posttest menjadi 1 dengan P-value 0,004. Intensitas mual muntah kelompok Pomelo pada pretest adalah 6.38 turun menjadi 1,75 pada saat posttest dengan P-value 0,000. Hasil uji lanjut didapatkan tidak ada perbedaan bermakna intensitas mual muntah antara kedua kelompok dengan Sig. 0,428.Kesimpulan : Pemberian Peppermint dan pomelo efektif dalam menurunkan intensitas mual dan muntah pada ibu hamil trimester I.Saran : Penelitian ini perlu disempurnakan dengan memperbesar sampel penelitian dan pengukuran intensitas mual muntah dapat dilakukan setiap hari selama penelitian mengingat penelitian ini hanya mengukur sebanyak dua kali pada 24 responden. Kata kunci : Mual, Muntah, Kehamilan, Peppermint, Pomelo 

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