scholarly journals Terapi pada Pasien Kanker Payudara Stadium Lanjut Menurunkan Kadar C- Reaktif Protein dan Meningkatkan Kadar Albumin

2019 ◽  
Vol 11 (2) ◽  
pp. 116
Author(s):  
Arya Wawolumaja ◽  
Victor Pontoh ◽  
Marselus Merung

Abstract: Breast cancer is one of the malignancies that has a high prevalence and can occur in both sexes. Albeit, more than 70% of these patients were detected at late stage. Inflammation could accelerate the tumor growth, invasion, angiogenesis, and metastasis. Increased serum CRP indicates uncontrolled infection or pathological process. Meanwhile, serum albumin is used to evaluate the nutrition status, the severity of disease, and prognosis. This study was aimed to evaluate the influence of serum CRP and albumin levels in female patients with breast cancer after treatment. This was an interventional analytical study with a cross sectional design. This study was conducted at Prof. Dr. R. D. Kandou Hosppital Manado. Subjects were all female patients with breast cancer from May to August 2018. The results showed that there were 43 patients of late stage breast cancer, mean age of 52.16 years. After treatment there was a decrease in the mean serum CRP level from 17.05 mg/dL to 6.40 mg/dL and the paired t test obtained a t value of 3.269 and a P value of 0.001. Moreover, there was an increase in the mean serum albumin level from 3.59 mg/L to 3.76 mg/L and the paired t test obtained a t value of -2,896 and a P value of =0.003. Conclusion: Chemotherapy and or surgery performed on female patients with breast cancer could decrease the serum CRP level and increase the serum albumin level.Keywords: breast cancer, serum CRP, serum albuminAbstrak: Kanker payudara merupakan salah satu jenis keganasan yang memiliki prevalensi cukup tinggi dan dapat terjadi baik pada laki-laki maupun perempuan. Lebih dari 70% penderita kanker payudara ditemukan pada stadium lanjut. Keadaan inflamasi dapat mempercepat pertumbuhan tumor, invasi, angiogenesis, dan metastasis. Hadirnya CRP serum yang meningkat mengindikasikan adanya infeksi atau proses patologik yang tidak teratasi. Albumin serum secara umum digunakan untuk menilai status nutrisi, derajat keparahan penyakit, perkembangan penyakit, dan prognosisnya. Penelitian ini bertujuan untuk menilai pengaruh kadar CRP dan albumin serum pada pasien perempuan dengan kanker payudara stadium lanjut setelah terapi. Jenis penelitian ialah intervensional analitik dengan desain potong lintang Penelitian dilakukan di RSUP Prof. Dr. R. D. Kandou Manado. Subjek penelitian ini ialah semua penderita kanker payudara berjenis kelamin perempuan pada periode Mei 2018 s/d Agustus 2018. Hasil penelitian mendapatkan 43 pasien dengan kanker payudara stadium lanjut dengan usia rerata 52,16 tahun. Setelah terapi terjadi penurunan rerata kadar CRP serum dari 17,05 mg/dL menjadi 6,40 mg/dL dan uji t berpasangan menunjukkan nilai t=3,269 dengan P=0,001. Selain itu, terjadi peningkatan rerata kadar albumin serum dari 3,59 mg/L menjadi 3,76 mg/L dan uji t berpasangan menunjukkan nilai t=-2,896 dengan P=0,003. Simpulan: Modalitas kemoterapi dan/atau operasi pada pasien kanker payudara stadium lanjut secara bermankna menurunkan kadar CRP serum tetapi meningkatkan kadar albumin serum.Kata kunci: kanker payudara, CRP serum, albumin serum

2017 ◽  
Vol 3 (6) ◽  
pp. 693-696
Author(s):  
Muhaji Muhaji ◽  
Bedjo Santoso ◽  
Putrono Putrono

Background: Endotracheal suctioning is one of the common supportive measures in intensive care units (ICU), which may be related to complications such as hypoxia. However, a questionable efficacy is still identified to choose suctioning pressure between 130 mmHg and 140 mmHg that is effective for patients with endotracheal tube.Objective: To compare the effectiveness of 130 mmHg and 140 mmHg suctioning pressure on oxygen saturation in patients with endotracheal tube.Methods: This research used a quasy experimental design with pretest and posttest group. The study was conducted from 31 January to 1 March 2017 in the Hospital of Panti Wilasa Citarum and Hospital of Roemani Muhammadiyah Semarang. There were 30 samples recruited using consecutive sampling, with 15 assigned in the 130 mmHg and 140 mmHg suctioning pressure group. Pulse oximetry was used to measure oxygen saturation. Paired t-test and Independent t-test were used for data analysis.Results: Findings showed that there was a statistically significant effect of 130 and 140 mmHg suctioning pressure on oxygen saturation in patients with ETT with p-value <0.05. There was a significant mean difference of oxygen saturation between 130 mmHg and 140 mmHg suctioning pressure group with p-value 0.004 (<0.05). The mean difference of oxygen saturation between both groups was 13.157.Conclusion: The 140 mmHg suctioning pressure is more effective compared with 130 mmHg suctioning pressure in increasing oxygen saturation in patients with ETT.


2021 ◽  
Vol 2 (1) ◽  
pp. 17-21
Author(s):  
Nidya Comdeca Nurvitriana ◽  
Setiana Andarwulan

Background of research on mother's knowledge of toddlers in providing feeding schedules, especially snacks. Giving snacks that are not right on schedule will have an influence on the growth and development of infants. Through the Emotional Demontration method, eating schedule for snacking can be controlled. Emotional Demonstration is the provision of education not only through lectures but also through games so that the key messages conveyed can be remembered by mothers of toddlers in Posyandu V Mulyorejo Surabaya. The Emo Demo method is one solution to reduce the stunting rate. In 2017 the stunting rate in Indonesia reached 22.2%. Based on the results of the survey conducted through interviews with nutritionists, it was explained that there were 16 stunting toddlers in Posyandu V Surabaya. Quantitative Research Methodology, a quasi-experimental research design method with one group pretest posttest approach. The population in this study were all mothers of children under five in Posyandu V Mulyorejo Surabaya as many as 36 people, samples as many as 36 mothers of toddlers. With a total sampling technique. Analyze data with Paired T-test. The results showed the mean value of the pre test was 6.06, the mean value after the post test reached 8.16. While the significance value of p value = 0,000 with α = 0.05 through the Paired T-test. The conclusion is that there are differences in the knowledge of pre and post test among mothers of children under five in Posyandu V Mulyorejo Surabaya, p value = 0,000 with α = 0.05. Suggestions for health workers to continue to make improvements in practicing emotional demonstration to participants because it is very useful in increasing knowledge to prevent increased stunting rates.


2018 ◽  
Vol 4 (1) ◽  
pp. 98-103
Author(s):  
Bernadeta Trihandini ◽  
Diyah Fatmasari ◽  
Lucia Endang Hartati YK ◽  
Sudirman Sudirman

Background: Anxiety in stroke patients occurs as a normal reaction to stress with life changes; however, when it becomes excessive, It becomes disabling. Effort to deal with anxiety is needed and spiritual approach nursing care is considered useful in caring patients with stroke.Objective: To examine the effect of spiritual nursing care on anxiety in stroke patients in the inpatient ward.Methods: This study used a quasy experimental design with pretest-postest control group. Thirty respondents were selected using consecutive sampling, which 15 respondents assigned in the experiment and control group. The Hamilton Anxiety Rating Scale was used to measure anxiety. Data were analyzed using paired t-test and independent t-test.Results: The results showed that the mean level of anxiety in the experiment group before intervention was 29.33 and decreased to 9 after intervention, while in the control group the mean level of anxiety before intervention was 29.47 and decreased to 17.73 after intervention. Paired t-test obtained p-value 0.000 (<0.05), which indicated that there was a significant effect of spiritual nursing care on anxiety levels in patients with stroke.Conclusion: Spiritual nursing care could reduce anxiety in patients with stroke. 


2019 ◽  
Vol 8 (2) ◽  
pp. 153-159
Author(s):  
Andikawati Fitriasari ◽  
Ahmad Yusuf ◽  
Ririn Probowati

Background: Breast cancer increases the occurrence of psychosocial problems, namely anxiety and depression. Anxiety and depression have shown an effect on the quality of life. Assertive Community Treatment is a psychosocial service that involves the family's role in overcoming breast cancer client anxiety and depression.Objective: This study aimed to determine the effect of Assertive Community Treatment towards anxiety and depression of breast cancer clients.Method: The research design used was quasi-experiment with a pre-posttest control group design. This research subject determines by using purposive sampling. The study population was breast cancer clients who seek treatment at Public Health Center of Medokan Ayu in Surabaya. The sample is breast cancer clients who have inclusion criteria a) age 30-60 years old, b) live with her partner, c) has chronic pain ± 1-5 years. The instrument is PDQBC (Psychosocial Distress Questionnaire Breast Cancer subscales anxiety and depression. Data analysis used paired T-Test and Independent T-Test.Result: Paired T test results showed anxiety values in the treatment group p = 0.000, depression value p = 0.001. The results of the independent T test statistic obtained p value = 0.000 showed a significant difference between anxiety and depression of breast cancer clients in the control group and the treatment group.Conclusion: Assertive Community Treatment provides a good impact in order to reduce the level of anxiety and depression in clients with breast cancer. Assertive Community Treatment (ACT) is recommended to be given by teams. Key words: Assertive Community Treatment, Anxiety, Depression, Breast Cancer Clients, Palliative.


2018 ◽  
Vol 4 (1) ◽  
pp. 104-111
Author(s):  
Chandra Irawan ◽  
Mardiyono Mardiyono ◽  
Suharto Suharto ◽  
Aris Santjaka

Background: Range of Motion (ROM) exercise has been identified in the literature that it has an effect in improving muscle strength, especially in patients with stroke. However, little is known about the effect of ROM exercise combined with hypnosis therapy.Objective: To determine the effect of combination of hypnosis therapy and ROM exercise on upper extremity muscle strength in patients with non-hemorrhagic.Methods: This study employed a quasy experiment with pretest-posttest control group design. Thirty-two samples were selected using simple random sampling, which 16 randomly assigned in the experiment and control group. Muscle strength was measured using Muscle Strength Scale. Hypnosis Deepening test was used to measure the level of hypnosis depth. Paired t-test and Independent t-test were used for data analysis.Results: The mean value of muscle strength in the experiment group was 3.50 and  the mean value in the control group  was 2.62. Independent sample t-test obtained p-value = 0.012, indicated that there was a statistically significant difference in the mean of muscle strength of upper extremity in the experiment and control group. Paired t-test obtained p-value = 0.000, which indicated that there was significant difference between the average of muscle strength value before and after treatmentConclusion: The combination of hypnosis therapy and ROM exercise has a significant effect in increasing muscle strength of upper extremity in patients with stroke non-haemorrhagic.


2020 ◽  
Vol 6 (1) ◽  
pp. 143-156
Author(s):  
Christine Aden ◽  
Marselinus Heriteluna

Postpartum recovery of the reproductive organs, especially the uterus, should occur immediately. The uterus should return to its pre-pregnancy size. Treatment to restore maternal health during the postpartum period was carried out by the Dayak community by using the herbal concoction of Tawas Ut (Ampelocissus Rubuginosa L). This study aims to determine the health status of post-partum mothers by administering the Tawas Ut herb as a food product. paired t-test). It was found that there was a significant difference in the mean fundal height between the intervention and control groups (p-value 0.012) with a difference of 2.91, or there was a difference of 61.1%. The results of the Paired t-test showed that there was a significant difference in the mean uterine fundal height between before and after the intervention period (p-value 0.0005) with a difference in uterine fundal height of 10.45 cm or a change of 84%. This shows that the local-based food of Tawas Ut has effects on the health status of postpartum mothers, which can reduce leukocytes by 32% and reduce uterine fundal height by 84% to normal sizes as before pregnancy. The use of this product is recommended to be used as a companion to standard service programs for postpartum mothers to support government programs to reduce maternal morbidity and mortality due to postpartum problems.


2018 ◽  
Vol 9 (2) ◽  
Author(s):  
Puput Nur Fadilah ◽  
Puji Astuti

Pain is a complaint which often happens to patients diagnosed with Cancer. Patients with breast cancer will feel pain when cancerous cells enlarge, wounds occur, and if metastasis happens. One of the simple ways to decrease the pain is to use hand massage relaxation technique. Therefore, this research was purposed to find out the effect of hand massage toward pain felt by patients with breast cancer. The research applied pre-experiment one group pre-post design. The population involved the patients with breast cancer experiencing pain. 11 respondents were chosen as the samples by using the probability sampling in which simple random sampling technique was applied in this research. The data were analyzed by using paired t-test. The result of research showed that before applying hand massage, the pain level was 5.09 on average, whereas the average pain level after applying hand massage was 3.09. It showed the difference on the pain level before and after applying hand massage. Furthermore, the result of research by using paired t-test showed that p value = 0.000 and α < 0.05. The research concluded that hand massage relaxation technique brought an effect toward the pain experienced by the patients with breast cancer. Hence, the nurses in hospital should be able to do this relaxation technique to make their patients relaxed so that they can be independent in fulfilling their daily needs. 


2021 ◽  
Vol 8 (2) ◽  
pp. 104
Author(s):  
Sri Wahyuni M.Keb ◽  
Fachry Amal ◽  
Ulfatunnisa Ulfatunnisa

ABSTRAKPermasalahan tentang menstruasi merupakan salah satu tantangan menggapai kesehatan reproduksi yang sehat bagi remaja. Tujuan penelitian ini untuk mengetahui perbedaan pengetahuan remaja putri sebelum dan sesudah diberikan penyuluhan dengan menggunakan  leaflet dan power point.Jenis penelitian ini adalah quasy eksperimen dengan melakukan pre test dan post test sebelum dan sesudah diberikan penyuluhan yang dilaksanakan pada Maret-April 2021 di kampung Putali wilayah kerja Puskesmas Ebungfauw. Sampel sejumlah 40 remaja putri. Intrument yang digunakan adalah media leaflet dan media power point dan kuesioner yang telah diuji validitas dan relibilitas. Analis data menggunakan uji Paired T-test dan uji Independen t-tes. Rerata pretest pengetahuan kelompok leaflet 53,00 dan posttest 61,25. Rerata pretest pengetahuan kelompok power point 59,75 dan posttest 78,75. Uji paired t-test pengetahuan kelompok leaflet yaitu p-value 0,000 dan pada kelempok power point yaitu p-value 0,000. Uji Efektifitas kelompok leaflet dan kelompok power point adalah 0,008 dengan perbedaan mean 10,00 kelompok leaflet dan mean 19,00 kelompok power point. Sehingga kelompok power point lebih efektif dalam meningkatkan pengetahuan remaja. Media power point lebih efektif dalam meningkatkan pengetahuan remaja putri tentang personal hygiene saat menstruasi. Kata Kunci : pengetahuan; personal hygiene; menstruasi; power point; leaflet ABSTRACT Menstruation is one of problems in achieving healthy reproductive female teenagers. The purpose of this study was to determine the difference in knowledge of female teenagers before and after being given counseling using leaflets and power point media.This research was a quasi-experimental study by conducting a pre-test before being given counseling and a post-test after being given counseling, carried out in March-April 2021 in Putali village, the working area of Ebungfauw Health Center. The sample of this research is 40 female teenagers. The instruments used are leaflet media and power point media and questionnaires that have been tested for validity and reliability. Data analysis used Paired T-test and Independent t-test. The mean of the pretest knowledge of the leaflet group was 53.00 and the posttest was 61.25. The mean of the pretest knowledge of the power point group was 59.75 and the posttest was 78.75. The paired t-test for the knowledge of the leaflet group is p-value 0.000 and for the power point group, the p-value is 0.000. The effectiveness test for the leaflet group and the power point group was 0.008 with a mean difference of 10.00 for the leaflet group and 19.00 for the power point group. So that the power point group is more effective in increasing the knowledge of teenagers. Power point media was more effective in increasing the knowledge of young women about personal hygiene during menstruation. Keywords: knowledg; personal hygiene; menstruation; power point; leaflet


2019 ◽  
Vol 6 (3) ◽  
pp. 401-407
Author(s):  
Anisa Ain ◽  
Desak Gede Agung ◽  
Esty Yunitasari

Background: Breast cancer is the most common type of cancer suffered by women. Cancer patients generally experience side effects of chemotherapy such as nausea and vomiting. Aim : The purpose of this study was to determine the effect of aromatherapy on nausea and vomiting of breast cancer patients undergoing chemotherapy. Method: this study is a true experimental study with a randomized pre-post-test design with a control group. The study sample was breast cancer patients with one day care chemotherapy at RSUD dr. Soetomo Surabaya. The sample was divided into 2 groups, the aromatherapy group (n = 20) and the control group (n = 20) collected consecutively in August to September 2019. Inhalation lavender aromatherapy is performed independently by patients at home every 2 times a day for 3 consecutive weeks (21 days). The instrument measures nausea and vomiting using the Rhodes Index Nausea, Vomiting and restcing. data analysis using paired t test. Results: The aromatherapy group had a mean difference of pre-post test -9.20, higher than the control group 0.30. Paired t test showed that there were significant differences in mean pre and post test in the aromatherapy group with p value <0.001 compared to the control group p 0.741 (> 0.05). Conclusion: lavender aromatherapy inhaled continuously for three consecutive weeks can reduce the nausea and vomiting of breast cancer patients undergoing chemotherapy


2020 ◽  
Vol 15 (1) ◽  
pp. 33
Author(s):  
As Ganda Prasetya ◽  
Melania Wahyuningsih ◽  
Anita Liliana

Background: The number of people who got a vasectomy in Indonesia is still low. The lack of knowledge is one of the factors that cause the low number of people who get a vasectomy. In order to increase the number of people who get a vasectomy, a health education about vasectomy is needed. Objective: To determine the influence of health education about vasectomy on the knowledge about and motivation to get a vasectomy. Methods: This is a quasi- experiment research with a one group pretest posttest design, the research samples were selected using a total sampling technique, the instruments used for this research were questionnaires, and the data collected were analyzed using Wilcoxon’s test and paired t-test. This research was conducted in Jelok hamlet, Beji village, with 31 fertile males involved as respondents. Results: Respondents’ knowledge score before health education was given showed a mean of 9, and after health education, the mean was 1.94. Motivation to get a vasectomy before health education was given showed a median score of 24, after health education was given, the median score was 26. Data analysis on knowledge about vasectomy using a paired t-test showed a p-value of 0.000. An analysis on motivation using Wilcoxon’s test showed a p-value of 0.003. Conclusion: There was a significant influence of health education about vasectomy on the knowledge about and motivation to get a vasectomy.


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