scholarly journals Bioactive compounds in the algae of Kappaphycus alvarezii from Belang waters, Southeast Minahasa Regency

2021 ◽  
Vol 9 (2) ◽  
Author(s):  
Dias Asthisa ◽  
Desy M.H. Mantiri ◽  
Deiske A. Sumilat ◽  
Rizal M. Rompas ◽  
Annita Ch. Sinjal ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Coastal Waters ◽  
Screening Test ◽  
Phthalic Acid ◽  
Marine Biology ◽  
Kappaphycus Alvarezii ◽  
Bioactive Compound ◽  
Health It ◽  
Nutritional Content ◽  
Ethylhexyl Phthalate

Algae Kappaphycus alvarezii is one of the leading commodities from fisheries and marine sectors in Indonesia. This algae species has many benefits in the fields of marine biology, chemistry, pharmacy, and pharmacology, as well as an excellent nutritional content for health. It is cultivated in the coastal waters of Minahasan Peninsula, especially in Buku Village, Belang District, Southeast Minahasa Regency. This study was carried out to analyze bioactive compound in the algae. Samples of 2-weeks old were taken directly from the cultivation area. Screening test was done qualitatively while an advanced test was done using LC-HRMS method. The results showed 4 bioactive compounds detected in the sample, they are alkaloids, tannins/phenolics, saponins, and flavonoids. From the advanced test, it was found 10 major compounds in the sample, i.e. (2-ethylhexyl) phthalate, phthalic acid, D-(+)-proline, maraniol, stigmatellin Y, Pentyl isopentyl phthalate, methyl thiofentanyl, phenylethanolamine, acetyl hexamethyl tetralin, and fucoxanthin.Indonesian title: Senyawa bioaktif pada alga Kappaphycus alvarezii dari perairan Belang, Kabupaten Minahasa Tenggara

scholarly journals Evaluasi Fisik Sediaan Krim Tabir Surya dari Bubur Rumput Laut Kappaphycus alvarezii dan Turbinaria conoides

2021 ◽  
Vol 10 (1) ◽  
pp. 1-8
Author(s):  
Rini Yanuarti ◽  
Nurjanah Nurjanah ◽  
Effionora Anwar ◽  
Ginanjar Pratama
Keyword(s):  
Bioactive Compounds ◽  
Kappaphycus Alvarezii ◽  
Bioactive Compound ◽  
Cycling Test ◽  
Physical Evaluation ◽  
Consistency Results ◽  
Turbinaria Conoides ◽  
Cosmetic Industry

Seaweed is one of the aquatic commodities which has many bioactive compounds. This bioactive compound is widely used in the cosmetic industry. In the cosmetic industry, usually has only one species of seaweed was used. The use of a combination of two seaweeds has not been widely used, therefore this study aims to determine the best sunscreen cream from the physical evaluation results of Kappaphycus alvarezii and Turbinaria conoides. The stages in this study were the making of seaweed porridge, formulation of sunscreen cream, and physical evaluation which included homogeneity, consistency of cream, cycling test, and organoleptic. In the homogeneity observation and cycling test, it was found that all treatments (cream concentration 0%, 10%, 20%, and 30%) had homogeneous and stable properties. The best cream consistency results were found in cream with 30% concentration (370x10–1). In organoleptic observations (appearance, color, and aroma) all creams with the addition of seaweed (cream concentration 10%, 20%, and 30%) were not significantly different. However, when compared to cream with 0% concentration, the results were significantly different. In this study, the sunscreen cream with the addition of 30% concentration of the combination of K. alvarezii and T. conoides is the best cream.

Chemodynamics, transport behaviour and treatment of phthalic acid esters in municipal landfill leachates

1998 ◽  
Vol 38 (2) ◽  
pp. 185-192 ◽  
Author(s):  
M. J. Bauer ◽  
R. Herrmann ◽  
A. Martin ◽  
H. Zellmann
Keyword(s):  
Particulate Matter ◽  
Aquatic Environment ◽  
Phthalic Acid ◽  
Phthalic Acid Esters ◽  
Landfill Leachates ◽  
Transport Behaviour ◽  
Ethylhexyl Phthalate ◽  
Dissolved Phase ◽  
Acid Esters ◽  
Long Chain

Large amounts of phthalic acid esters (PAEs) are leached from plastics dumped at municipal landfills. This leachate transports PAEs either adsorbed on particulate matter or in dissolved phase. Dissolved organic macromolecules, mainly humic-like substances, enhance the solubility of PAEs. In the biochemical environments of municipal landfills short chain PAEs can be degraded by base-catalyzed hydrolysis or by microorganisms which enzymatically split the side chains. However, there is no cleavage of the aromatic ring. Long chain PAEs like di-(2-ethylhexyl) phthalate are neither degraded abiotically nor by microorganisms. Hence, these PAEs can be leached and washed out of leaky landfills into the groundwater and thus continue to be a threat to the aquatic environment. Only a combined UV radiation/ozonation treatment is capable of fully destroying PAEs.

scholarly journals Ultrasonic Extraction of Bioactive Compounds From Green Soybean Pods and Application in Green Soybean Milk Antioxidants Fortification

2021 ◽  
Author(s):  
Noppol Leksawasdi ◽  
Siraphat Taesuwan ◽  
Trakul Prommajak ◽  
Charin Techapun ◽  
Rattanaporn Khonchaisri ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Bioactive Compounds ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Bioactive Compound ◽  
Natural Antioxidants ◽  
Dependent Manner ◽  
Ultrasound Technique ◽  
Antioxidant Power ◽  
Soybean Milk

Abstract Green soybean (Glycine max L.) pods (GSP) are agro-industrial waste from the production of frozen green soybean and milk. These pods contain natural antioxidants and various bioactive compounds that are still underutilized. Polyphenols and flavonoids in GSP were extracted by ultrasound techniques and used in antioxidant fortification of green soybean milk. The ultrasound extraction that yielded the highest total polyphenol content was 50% amplitude for 10 min, whereas maximum flavonoids content was obtained at 50% amplitude for 15 min. Radical scavenging activity assayed by 2,2-diphenyl-1-picryl-hydrazyl radical (DPPH) and ferric reducing antioxidant power (FRAP) methods did not differ significantly (p>0.05) between the two conditions. Response surface methodology was applied to analyze an optimum ultrasonic-assisted extraction (UAE) condition of these variables. The highest desirability was found to be 50% amplitude with extraction time of 12.5 min. Fortification of the GSP extracts (1-3% v/v) in green soybean milk resulted in higher levels of bioactive compounds and antioxidant activity in a dose-dependent manner. Procyanidins were found to be the main polyphenols in dried GSP which were present at the concentration of 104.1 ± 2.1 mg/g dry sample, respectively. Addition of GSP extracts obtained by using an ultrasound technique to green soybean milk increased its bioactive compound content especially procyanidins as well as its antioxidant activity.

scholarly journals Enhancing or Inhibitory Effect of Fruit or Vegetable Bioactive Compound on Aspergillus niger and A. oryzae

2021 ◽  
Vol 8 (1) ◽  
pp. 12
Author(s):  
Gülru Bulkan ◽  
Sitaresmi Sitaresmi ◽  
Gerarda Tania Yudhanti ◽  
Ria Millati ◽  
Rachma Wikandari ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Aspergillus Niger ◽  
Bioactive Compounds ◽  
Ellagic Acid ◽  
Microbial Growth ◽  
Biomass Yield ◽  
Antimicrobial Effect ◽  
Bioactive Compound ◽  
Inhibitory Effect ◽  
Processing Wastes

Fruit and vegetable processing wastes are global challenges but also suitable sources with a variety of nutrients for different fermentative products using bacteria, yeast or fungi. The interaction of microorganisms with bioactive compounds in fruit waste can have inhibitory or enhancing effect on microbial growth. In this study, the antimicrobial effect of 10 bioactive compounds, including octanol, ellagic acid, (−)-epicatechin, quercetin, betanin, ascorbic acid, limonene, hexanal, car-3-ene, and myrcene in the range of 0–240 mg/L on filamentous fungi Aspergillus oryzae and Aspergillus niger were investigated. These fungi were both found to be resistant to all compounds except octanol, which can be used as a natural antifungal agent, specifically against A. oryzae and A. niger contamination. On the contrary, polyphenols (quercetin and ellagic acid), ascorbic acid, and hexanal enhanced A. niger biomass yield 28%, 7.8%, 16%, and 6%, respectively. Furthermore, 240 mg/L car-3-ene was found to increase A. oryzae biomass yield 8%, while a 9% decrease was observed at lower concentration, 24 mg/L. Similarly, up to 17% decrease of biomass yield was observed from betanin and myrcene. The resistant nature of the fungi against FPW bioactive compounds shows the potential of these fungi for further application in waste valorization.

scholarly journals Kombucha Tea—A Double Power of Bioactive Compounds from Tea and Symbiotic Culture of Bacteria and Yeasts (SCOBY)

Antioxidants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1541
Author(s):  
Hubert Antolak ◽  
Dominik Piechota ◽  
Aleksandra Kucharska
Keyword(s):  
Bioactive Compounds ◽  
Biological Activities ◽  
Alcoholic Beverage ◽  
Antimicrobial Properties ◽  
Bioactive Compound ◽  
Acetic Acid Bacteria ◽  
Kombucha Tea ◽  
Health Promoting ◽  
Fermentation Parameters ◽  
Herb Extracts

Kombucha is a low alcoholic beverage with high content of bioactive compounds derived from plant material (tea, juices, herb extracts) and metabolic activity of microorganisms (acetic acid bacteria, lactic acid bacteria and yeasts). Currently, it attracts an increasing number of consumers due to its health-promoting properties. This review focuses on aspects significantly affecting the bioactive compound content and biological activities of Kombucha tea. The literature review shows that the drink is characterized by a high content of bioactive compounds, strong antioxidant, and antimicrobial properties. Factors that substantially affect these activities are the tea type and its brewing parameters, the composition of the SCOBY, as well as the fermentation parameters. On the other hand, Kombucha fermentation is characterized by many unknowns, which result, inter alia, from different methods of tea extraction, diverse, often undefined compositions of microorganisms used in the fermentation, as well as the lack of clearly defined effects of microorganisms on bioactive compounds contained in tea, and therefore the health-promoting properties of the final product. The article indicates the shortcomings in the current research in the field of Kombucha, as well as future perspectives on improving the health-promoting activities of this fermented drink.

scholarly journals FAKTOR PENGELOLAAN YANG MEMPENGARUHI TINGKAT PRODUKSI RUMPUT LAUT Kappaphycus alvarezii DI PERAIRAN PANTAI SELATAN PROVINSI SULAWESI SELATAN

2016 ◽  
Vol 5 (3) ◽  
pp. 491
Author(s):  
Erna Ratnawati ◽  
Akhmad Mustafa ◽  
Rohama Daud
Keyword(s):  
Coastal Waters ◽  
Management Practices ◽  
Kappaphycus Alvarezii ◽  
The South ◽  
Dummy Variable ◽  
South Sulawesi ◽  
Yield Production ◽  
Long Line ◽  
Seed Origin ◽  
Seaweed Production

Perairan pantai Kabupaten Jeneponto, Bantaeng, dan Bulukumba merupakan sentra produksi rumput laut Kappaphycus alvarezii di Sulawesi Selatan. Pengelolaan budidaya yang dilakukan oleh pembudidaya di daerah tersebut cukup bervariasi sehingga dilakukan penelitian yang bertujuan untuk mengetahui faktor pengelolaan budidaya yang mempengaruhi produksi rumput laut. Metode survai melalui pengajuan kuesioner kepada 62 responden secara terstruktur. Sebagai peubah tidak bebas dalam penelitian ini adalah produksi rumput laut, sedangkan peubah bebas adalah faktor pengelolaan budidaya. Analisis regresi berganda dengan peubah boneka digunakan untuk memprediksi produksi rumput laut. Hasil penelitian menunjukkan bahwa produksi rumput laut di perairan selatan Sulawesi Selatan berkisar antara 463-5.000 dengan rata-rata 1.502,3 kg kering/3.000 m2 yang dibudidayakan dengan tali panjang. Faktor pengelolaan budidaya yang mempengaruhi produksi rumput laut adalah jarak antar tali ris, jarak antar rumpun dalam tali ris, hama baronang, penyakit ice-ice, bobot bibit, asal bibit dan sumber cemaran. Untuk meningkatkan produksi rumput laut di perairan selatan Sulawesi Selatan dapat dilakukan melalui peningkatan bobot bibit antara 36,9 sampai 100,0 g/rumpun, menggunakan bibit yang tidak diangkut terlalu lama, tidak menambah jarak antar tali ris sampai melebihi 1,0 m, tidak menambah jarak antar rumpun dalam tali ris yang melebihi 25 cm serta melakukan penanaman berdasar kalender musim tanam untuk mencegah terjadinya serangan hama dan penyakit serta cemaran.Coastal waters of Jeneponto, Bantaeng, and Bulukumba Regencies are the centre of seaweed Kappaphycus alvarezii production in South Sulawesi. Culture management practices applied by farmers in these areas are highly variable. Therefore, this research was conducted to study culture management practices affect the seaweed production in the area. Field survey was conducted by interviewing 62 respondents using questionnaires. The dependent variable in this research was seaweed production, while the independent variables were culture management factors. Multiple regressions with dummy variable were employed to analyze the data to predict seaweed production. The results show that the seaweed productions per one cycle in the south coastal waters of South Sulawesi were ranging from 463 to 5,000 kg dry/3,000 m2. Using long line method, the average yield production was 1,502.3 kg dry/3,000 m2. Culture management practices that affect the seaweed production were distance between ropes, distance between seaweed seeds along the rope, rabbitfish predatory, ice-ice disease, weight of seed, seed origin, and source of pollution. Increasing seaweed production in the south coastal waters of South Sulawesi could be done through increasing weight of seed from 36.9 to 100.0 g/clump, quicker transport of seed, maintaining the distance between the ropes not more than 1.0 m, not increasing the distance between clump along the ropes more than 25 cm along as well as conducting seed planting based on cultivating season to prevent pest diseases and pollution.

scholarly journals HCIP: An Online database for prediction CYP450 Enzyme Inhibition potential of bioactive compounds

2021 ◽  
Vol 11 (2) ◽  
pp. 253-255
Author(s):  
Sabarathinam Sarvesh ◽  
Preethi L ◽  
Haripritha Meganathan ◽  
M Arjun Gokulan ◽  
Dhivya Dhanasekaran ◽  
...  
Keyword(s):  
Drug Interaction ◽  
Drug Interactions ◽  
Enzyme Inhibition ◽  
Bioactive Compounds ◽  
Bioactive Compound ◽  
Concomitant Administration ◽  
Cyp3a4 Inhibitor ◽  
Online Database ◽  
Computer Aided ◽  
Cyp450 Enzyme

Background: Concomitant administration of herbal medicine and conventional may lead to severe metabolism-oriented herb-drug interactions. However, detecting herb-drug interaction is expensive and higher time-consuming. Several computer-aided techniques have been proposed in recent years to predict drug interactions. However, most of the methods cannot predict herb-drug interactions effectively. Methods: Canonical SMILES of bioactive compounds was gathered from the PubChem online database, and its inhibition details were gathered PKCSM from the webserver. Results: By searching the bioactive compound name in the search bar of “The Herb-CYP450 Enzyme Inhibition Predictor online database” (HCIP- http://hcip.in/), it will provide the liver enzyme inhibition profile of the selected bioactive compound. For example; Guggulsterone:  CYP3A4 inhibitor.  Conclusion: The Herb-CYP450 Enzyme Inhibition Predictor online database is very peculiar and easy to determine the inhibition profile of the targeted bioactive compound. Keywords: CYP450; Enzyme inhibition; Bioactive Compounds; Online database; Herb-Drug Interaction

scholarly journals Characterization and Bioactive Compound Analysis of Meretrix meretrix Linnaeus

Marinade ◽  
2018 ◽  
Vol 1 (01) ◽  
pp. 01-09
Author(s):  
Azwin Apriandi ◽  
Kustiariyah Tarman ◽  
Purwantiningsih Sugita
Keyword(s):  
Heavy Metals ◽  
Heavy Metal ◽  
Bioactive Compounds ◽  
Methanol Extract ◽  
Bioactive Compound ◽  
Morphological Characterization ◽  
Proximate Analysis ◽  
Meretrix Meretrix ◽  
White Meat ◽  
Yellowish White

Meretrix meretrix was one of gastropods seawater has been used by people as a food. These shells are still categorized of bycatch and have not explored the benefits. This study aimed to characterize and analyze the content of bioactive Meretrix meretrix. This research was conducted morphological characterization shellfish sensory, measurement of yield, the content of the proximate analysis, heavy metals and analysis of bioactive compounds from the extracts of water and methanol. Observation found that the Meretrix meretrix has a yellowish white color with black bars at the end of the shell and the white meat and chewy with a yield of meat and shells of 11.09% and 69.85%. Analysis of water content, ash, fat, protein, and carbohydrates respectively by 79.99%, 1.50%, 0.22%, 9.42%, and 8.81%. Heavy metal obtained 8x10-4 ppm Hg content, 13x10-4 ppm Pb, Cd, and Cu 45x10-4 and 88x10-4 ppm. Bioactive compounds in water and methanol extract of shellfish Lamis including alkaloids, steroids, and saponins.

scholarly journals Traditionally Used Sideritis cypria Post.: Phytochemistry, Nutritional Content, Bioactive Compounds of Cultivated Populations

2020 ◽  
Vol 11 ◽  
Author(s):  
Krystalia Lytra ◽  
Ekaterina-Michaela Tomou ◽  
Antonios Chrysargyris ◽  
Chryssoula Drouza ◽  
Helen Skaltsa ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Nutritional Content ◽  
Cultivated Populations
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