scholarly journals Kombucha Tea—A Double Power of Bioactive Compounds from Tea and Symbiotic Culture of Bacteria and Yeasts (SCOBY)

Antioxidants ◽  
2021 ◽  
Vol 10 (10) ◽  
pp. 1541
Author(s):  
Hubert Antolak ◽  
Dominik Piechota ◽  
Aleksandra Kucharska
Keyword(s):  
Bioactive Compounds ◽  
Biological Activities ◽  
Alcoholic Beverage ◽  
Antimicrobial Properties ◽  
Bioactive Compound ◽  
Acetic Acid Bacteria ◽  
Kombucha Tea ◽  
Health Promoting ◽  
Fermentation Parameters ◽  
Herb Extracts

Kombucha is a low alcoholic beverage with high content of bioactive compounds derived from plant material (tea, juices, herb extracts) and metabolic activity of microorganisms (acetic acid bacteria, lactic acid bacteria and yeasts). Currently, it attracts an increasing number of consumers due to its health-promoting properties. This review focuses on aspects significantly affecting the bioactive compound content and biological activities of Kombucha tea. The literature review shows that the drink is characterized by a high content of bioactive compounds, strong antioxidant, and antimicrobial properties. Factors that substantially affect these activities are the tea type and its brewing parameters, the composition of the SCOBY, as well as the fermentation parameters. On the other hand, Kombucha fermentation is characterized by many unknowns, which result, inter alia, from different methods of tea extraction, diverse, often undefined compositions of microorganisms used in the fermentation, as well as the lack of clearly defined effects of microorganisms on bioactive compounds contained in tea, and therefore the health-promoting properties of the final product. The article indicates the shortcomings in the current research in the field of Kombucha, as well as future perspectives on improving the health-promoting activities of this fermented drink.

scholarly journals Pinus Species as Prospective Reserves of Bioactive Compounds with Potential Use in Functional Food—Current State of Knowledge

Plants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1306
Author(s):  
Marcin Dziedziński ◽  
Joanna Kobus-Cisowska ◽  
Barbara Stachowiak
Keyword(s):  
Human Health ◽  
Bioactive Compounds ◽  
Functional Food ◽  
Biological Activities ◽  
Food Ingredients ◽  
Beneficial Effects ◽  
Pine Tree ◽  
Pine Trees ◽  
Health Promoting ◽  
Few Data

The pine (Pinus L.) is the largest and most heteromorphic plant genus of the pine family (Pinaceae Lindl.), which grows almost exclusively in the northern hemisphere. The demand for plant-based remedies, supplements and functional food is growing worldwide. Although pine-based products are widely available in many parts of the world, they are almost absent as food ingredients. The literature shows the beneficial effects of pine preparations on human health. Despite the wide geographical distribution of pine trees in the natural environment, there are very few data in the literature on the widespread use of pine in food technology. This study aims to present, characterise and evaluate the content of phytochemicals in pine trees, including shoots, bark and conifer needles, as well as to summarise the available data on their health-promoting and functional properties, and the potential of their use in food and the pharmaceutical industry to support health. Various species of pine tree contain different compositions of bioactive compounds. Regardless of the solvent, method, pine species and plant part used, all pine extracts contain a high number of polyphenols. Pine tree extracts exhibit several described biological activities that may be beneficial to human health. The available examples of the application of pine elements in food are promising. The reuse of residual pine elements is still limited compared to its potential. In this case, it is necessary to conduct more research to find and develop new products and applications of pine residues and by-products.

scholarly journals Identifying Antibacterial Compounds in Black Walnuts (Juglans nigra) Using a Metabolomics Approach

Metabolites ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 58 ◽  
Author(s):  
Khanh-Van Ho ◽  
Zhentian Lei ◽  
Lloyd Sumner ◽  
Mark Coggeshall ◽  
Hsin-Yeh Hsieh ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Cost Effective ◽  
Bioactive Compound ◽  
The United States ◽  
Black Walnut ◽  
Juglans Nigra ◽  
Compound Identification ◽  
Antibacterial Compounds ◽  
Nut Production ◽  
Health Promoting

Black walnut (Juglans nigra L.) is one of the most economically valuable hardwood species and a high value tree for edible nut production in the United States. Although consumption of black walnut has been linked to multiple health-promoting effects (e.g., antioxidant, antimicrobial, anti-inflammatory), the bioactive compounds have not been systematically characterized. In addition, the associations between different black walnut cultivars and their health-promoting compounds have not been well established. In this study, the kernels of twenty-two black walnut cultivars selected for nut production by the University of Missouri Center for Agroforestry (Columbia, MO, USA) were evaluated for their antibacterial activities using agar-well diffusion assay. Among the selected cultivars, four black walnut cultivars (i.e., Mystry, Surprise, D.34, and A.36) exhibited antibacterial activity against a Gram-positive bacterium (Staphylococcus aureus), whereas other cultivars showed no effect on the inhibition of this bacterium. The antibacterial compounds showing the strongest activity were isolated with bioassay-guided purification and identified using a metabolomics approach. Six antibacterial bioactive compounds responsible for antimicrobial activity were successfully identified. Glansreginin A, azelaic acid, quercetin, and eriodictyol-7-O-glucoside are novel antibacterial compounds identified in the kernels of black walnuts. The metabolomics approach provides a simple and cost-effective tool for bioactive compound identification.

scholarly journals Differences in Bioactive Protein and Vitamin Status of Milk Obtained from Polish Local Breeds of Cows

2020 ◽  
Vol 20 (1) ◽  
pp. 287-298 ◽  
Author(s):  
Aneta Brodziak ◽  
Jolanta Król ◽  
Joanna Barłowska ◽  
Zygmunt Litwińczuk ◽  
Anna Teter ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Whey Proteins ◽  
Antioxidant Properties ◽  
Antimicrobial Properties ◽  
Processing Plant ◽  
Vitamin Status ◽  
Holstein Friesian ◽  
Health Promoting ◽  
Β Lactoglobulin ◽  
Β Carotene

AbstractThe aim of the study was to compare the content of selected bioactive whey proteins and lipophilic vitamins, which largely determine the bioactive status of milk, in milk obtained from local breeds of cows raised in Poland (Polish Red, White-Backed and Simmental) and Polish Holstein-Friesian cows. Basic chemical composition and content of selected bioactive compounds (β-lactoglobulin, α-lactalbumin, lactoferrin, bovine serum albumin, and vitamins: E, A, D3 and β-carotene) in 550 milk samples were analysed. The milk produced by local breeds proved to be a more valuable source of whey proteins and lipophilic vitamins than that of the Polish Holstein-Friesians. It was distinguished by its content of all bioactive compounds, including those with antioxidant properties, i.e. vitamins E, A and D3 and β-lactoglobulin, and antimicrobial properties, mainly lactoferrin. Therefore, the milk of cows of local breeds should be considered a valuable material for processing, especially at the level of the farm or small local processing plant, to produce products that are richer in health-promoting compounds. The promotion of milk from local breeds can therefore be an opportunity for the farms that raise them.

scholarly journals Critical review of fermentation and extraction of anti-Vibrio compounds from Streptomyces

2020 ◽  
Vol 3 (1) ◽  
Author(s):  
Loh Teng-Hern Tan ◽  
Learn-Han Lee ◽  
Bey-Hing Goh
Keyword(s):  
Secondary Metabolism ◽  
Secondary Metabolite ◽  
Bioactive Compounds ◽  
Critical Review ◽  
Antibacterial Agent ◽  
Bioactive Compound ◽  
Streptomyces Strain ◽  
Streptomyces Sp ◽  
Microbial Products ◽  
Fermentation Parameters

A single Streptomyces strain often have the potential to produce more than one bioactive compound. Fermentation parameters include media compositions, temperature and pH, have great impact on the secondary metabolism of Streptomyces and subsequently on production of different microbial products. This review aims to consolidate the studies on the cultivation parameters used to enhance the production of secondary metabolite with anti-Vibrio activity from a single Streptomyces strain. In turn, this review sheds light on the possible alterations of the cultivation parameters to obtain desired anti-Vibrio compounds from Streptomyces sp. Furthermore, the bioactive compounds with anti-Vibrio activity identified from Streptomyces sp. were demonstrated to exhibit immense values for future antibacterial agent developments.

scholarly journals A review on phytoconstituents of marine brown algae

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Masuma M. Hakim ◽  
Illa C. Patel
Keyword(s):  
Bioactive Compounds ◽  
Brown Algae ◽  
Marine Algae ◽  
Biological Activities ◽  
Bioactive Compound ◽  
Biological Properties ◽  
Main Body ◽  
Marine Brown Algae ◽  
Hard State ◽  
Gujarat Coast

Abstract Background From the last few years, the development and discovery of bioactive compounds and their potential properties from marine algae have been enhanced significantly. The coastal area is a huge storehouse for propitious algae. It has been the genuine reality that the consequence of marine algae as a source of different compounds is increasing. Main body Numerous advanced research devices are available for the discovery of synthetic compounds but still many researchers are working on natural bioactive compounds to discover their biological properties, which are useful to society. Marine algae are taking the preponderance of consideration from investigators owing to its phenomenon of biological activity like anti-cancer, anti-viral, cholesterol-reducing, and many more. A variety of compounds are collected from algae with specific purposes as they remain in an extremely ambitious and hard state; this condition is responsible for the synthesis of very particularly effective bioactive compounds. The present article is concentrating on the brown algae of the Gujarat coast, phlorotannins, polyphenol, phytosterol from brown algae, and their various applications. The main importance has been given to the secondary metabolites and various applications of marine brown algae. Conclusion From this review, it can be concluded that the prominent bioactive compounds from brown algae can cure many serious diseases. Besides, the potential biological activities of a special bioactive compound may represent the interest in the industry of pharmaceuticals, cosmeceutical, and functional foods.

scholarly journals Finger millet bioactive compounds, bioaccessibility, and potential health effects – a review  

2017 ◽  
Vol 35 (No. 1) ◽  
pp. 7-17 ◽  
Author(s):  
Udeh Henry Okwudili ◽  
Duodu Kwaku Gyebi ◽  
Jideani Afam Israel Obiefuna
Keyword(s):  
Ferulic Acid ◽  
Health Effects ◽  
Bioactive Compounds ◽  
Finger Millet ◽  
Antimicrobial Properties ◽  
Cereal Grains ◽  
Potential Health ◽  
Recent Interest ◽  
Important Health ◽  
Health Promoting

Finger millet is among minor cereal grains that are underutilised. However, over the years, research interest in the millet has increased owing to its abundance of bioactive compounds. These compounds which include, among others, ferulic acid-rich arabinoxylans or feraxans, ferulic acid, caffeic acid, and quercetin have been associated with certain health promoting properties and have been found bioaccessible in the grain. Following the recent interest in natural curative substances over their synthetic counterparts in the treatment of food dependent diseases, finger millet has shown potential nutraceutical effects. Some important health effects such as antidiabetic, antioxidative, anti-inflammatory and antimicrobial properties have been reported in recent trials with the grain. This review emphasises the dietary fibre – arabinoxylan, and phenolic compounds of finger millet and their properties, and further discusses available evidence on their bioaccessibility and bioactivity. The information presented will further explore the potential of finger millet utilisation, its bioactive compounds, bioaccessibility, and potential health benefits, in view of stimulating further research.

scholarly journals Extraction, Isolation and Characterization of Bioactive Compounds from Artemisia and Their Biological Significance: A Review

Molecules ◽  
2021 ◽  
Vol 26 (22) ◽  
pp. 6995
Author(s):  
Rosemary Anibogwu ◽  
Karl De Jesus ◽  
Samjhana Pradhan ◽  
Srinath Pashikanti ◽  
Sameena Mateen ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Artemisia Annua ◽  
Biological Activities ◽  
Biological Significance ◽  
Bioactive Compound ◽  
World Health ◽  
Isolation And Characterization ◽  
Artemisia Species ◽  
Health Organization ◽  
Different Cultures

Diverse medicinal plants such as those from the genus Artemisia have been employed globally for centuries by individuals belonging to different cultures. Universally, Artemisia species have been used to remedy various maladies that range from simple fevers to malaria. A survey conducted by the World Health Organization (WHO) demonstrated that 80% of the global population is highly reliant on herbal medicine for their primary healthcare. WHO recommends artemisinin-based combination therapies (ACT) for the treatment of global diseases such as malaria. Artemisinin is a bioactive compound derived from Artemisia annua leaves. It is a sesquiterpene endoperoxide with potent antimalarial properties. This review strives to instill natural products to chemists and others in diverse fields with a heterogeneous set of knowledge compiled from multifaceted researchers and organizations in literature. In particular, the various Artemisia species and effective extraction, isolation, and characterization methodologies are discussed in detail. An in-depth investigation into the literature reveals that divergent species of Artemisia exhibit a vast array of biological activities such as antimalarial, antitumor, and anti-inflammatory activities. There is substantial potential for bioactive compounds from Artemisia to provide significant relief from differing human ailments, but more meticulous research in this field is needed.

scholarly journals Docking Studies on Ache and Tau Proteins with Marine Bioactive Compound Squalene, A New Approach to Design Anti-Alzheimer’s Drug Targets

2021 ◽  
Vol 70 (2) ◽  
Author(s):  
Praveen Kukkarasapalli ◽  
Yellamma Kuna
Keyword(s):  
Bioactive Compounds ◽  
Drug Targets ◽  
Biological Activities ◽  
Senile Plaques ◽  
Docking Simulation ◽  
Bioactive Compound ◽  
Docking Studies ◽  
Complex Compounds ◽  
Tau Proteins ◽  
Neuroprotective Effects

Natural bioactive compounds of Marine origin have attracted the attention of many biologists and chemists in the world over for the last five decades because it has proven to be a rich source of structurally diverse and complex compounds exhibiting numerous interesting biological functions. At present, many research findings have provided insight into biological activities of marine natural compounds such as antioxidant- and anti-cholinesterase activity and neuroprotective effects on neurodegenerative diseases, viz. Alzheimer’s and Parkinson’s. The main pathological hallmarks of AD is the formation senile plaques, neurofibrillary tangles and the most incredible physiological and biochemical changes are reduction in acetylcholine (ACh) levels in the hippocampus and cortex of the brain and loss of memory, decaying language etc. Present study is focused on to enhance the acetylcholine levels and subsequently to prevent the formation of Senile Plaques and Neuro Fibrillary Tangles in tau protein responsible for Alzheimer’s disease by using natural bioactive compound Squalene. Computational Biology and Bio-informatics have the potential not only to speed up the drug discovery process but reduces the costs. Further, they also change the way drugs are designed by using Docking Techniques employed to dock a set of marine bioactive compounds within the active site region of 1B41 & 2V17 by using Auto Dock vina. The docking simulation clearly predicted the interaction and highest binding energy docking scores against Squalene, analogues were retrieved from ZINC database i.e. ZINC 0118 (-8.9) and ZINC 0142 (-8.3) for 4B05 & 2V17 enzymes respectively. Further, we Studied visualization aspects in PyMol and also satisfied the biological activity predictions like OSIRIS, Molinspiration and PASS Prediction results by inhibiting the activity of Tau and Acetyl Cholinesterase receptors in AD.

scholarly journals The Profile of Secondary Metabolites and Other Bioactive Compounds in Cucurbita pepo L. and Cucurbita moschata Pumpkin Cultivars

Molecules ◽  
2019 ◽  
Vol 24 (16) ◽  
pp. 2945 ◽  
Author(s):  
Bartosz Kulczyński ◽  
Anna Gramza-Michałowska
Keyword(s):  
Chemical Composition ◽  
Bioactive Compounds ◽  
Phenolic Acids ◽  
Nutritional Value ◽  
Cucurbita Pepo ◽  
Protocatechuic Acid ◽  
Bioactive Compound ◽  
Cucurbita Moschata ◽  
The World ◽  
Health Promoting

Plants and animals are sources of various bioactive compounds that exhibit a broad spectrum of health-promoting effects. Scientists continue studies on the chemical composition of many products in search of foods with high nutritional value. The pumpkin (Cucurbita sp.) is unquestionably a source of valuable nutrients. This vegetable is well-known all over the world and it is appreciated due to its high content of carotenoids, but it is still not much used in the processing industry. The aim of present study was to compare the flesh of 15 pumpkin varieties belonging to the Cucurbita pepo and C. moschata species in terms of the bioactive compound content (carotenoids, phenolic acids, flavonols, minerals and vitamins) and to demonstrate whether the variety has an effect on the chemical composition. To date, no such extensive research has been carried out in this area. The research revealed that the pumpkin pulp had high content of carotenoids. In nearly all cases lutein was the most abundant carotenoid. Numerous phenolic acids and flavonols were also identified. All the cultivars contained gallic acid, protocatechuic acid, 4-hydroxybenzoic acid, vanillic acid, chlorogenic acid, caffeic acid, and rutin. The pumpkin pulp also contained alpha- and gamma-tocopherol. No beta- or delta-tocopherol was found. Potassium, calcium, and sodium were the most abundant minerals. The research also proved that the profile of bioactive compounds in the pumpkin pulp was considerably diversified and depended on the species and cultivar

scholarly journals Kamkatın (Fortunella spp.) Biyoaktif Bileşenleri ve Biyolojik Aktiviteleri

2019 ◽  
Vol 7 (10) ◽  
pp. 1581
Author(s):  
Demet Yıldız Turgut ◽  
Ayhan Topuz
Keyword(s):  
Ascorbic Acid ◽  
Essential Oil ◽  
Dietary Fiber ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Health Benefits ◽  
Health Promoting

Kumquat (Fortunella spp.), is called "the little gems of the citrus family", belongs in the genus Fortunella of the Rutaceae family. Kumquat is known native to China. It is widely cultıvated in China, Japan and America. Recent studies have been reported that kumquat fruit possesses health promoting effects duo to its bioactive compounds including ascorbic acid, carotenoids, essential oil, dietary fiber and flavonoids. The fruit can be consumed as fresh and also processed into different products such as; jam, marmalade, wine, liqueur, fruit tea etc. Its essential oil and extracts can be used in food, pharmaceutical and cosmetic industries. Since the health benefits of kumquat fruits were understood, its cultivation and production have been increased in Turkey in recent years. In present study, the studies on the bioactive compounds and biological activities of kumquat fruit are reviewed.

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