scholarly journals FETOMATERNAL OUTCOMES IN PREEKLAMPSIA PATIENTS WITH PROTEINURIA AND WITHOUT PROTEINURIA

2019 ◽  
pp. 1-5
Author(s):  
Putri Aini Daulay

BACKGROUND AND OBJECTIVES : The high maternal mortality rate is still found mainly in Southeast Asia including Indonesia. Maternal deaths that occur are caused by various things. High blood pressure during pregnancy (preeclampsia and eclampsia) is one of the major causes of maternal death in the world besides heavy bleeding (usually postpartum) and infection. The relationship between proteinuria and poor fetal outcomes has been investigated by experts,increasing protein excretion in women with preeclampsia (PE) is generally associated with poor maternal and fetal (fetomaternal) outcomes, proteinuria levels in women with PE are poor predictors of outcomes fetomaternal. But another opinion says that proteinuria is not an absolute criterion that must be found to diagnose PE, where multiorgan dysfunction in PE patients with or without proteinuria does not have a significant difference. From these results the researchers wanted to know the fetomaternal outcomes of PE patients with proteinuria (+ 1, + 2, + 3, + 4) and preeclampsia without proteinuria. METHODS :This research is a descriptive study with a retrospective design,carried out using secondary data analysis of patients diagnosed with PE with or without proteinuria and have been terminated.This research was conducted at the General Hospital. H. Adam Malik Medan. The time of the study is from October 2017 to February 2018. The study population is PE patients treated and terminated from February 2013 to May 2017. PE patients in this study will henceforth be assessed based on protein levels in the urine (proteinuria). The sample size in this study uses the Lemeshow formula which aims to find a large proportion in a population. RESULTS: A total of 62 PE women with proteinuria and 21 PE women without proteinuria. Of all the samples, maternal and fetal outcomes were assessed.Based on Proteinuria,research subjects who were diagnosed with PE with proteinuria were 62 people.The highest number was 36.1% in PE with proteinuria + 3,followed by 18.1% in PE with proteinuria +1, then as much as 15.7% in PE with proteinuria +4,and with the smallest amount of 4.8% in PE with proteinuria +2.Research subjects diagnosed with PE without proteinuria totaled 21 people,as many as 25.3% of the total sample. CONCLUSION : Most research subjects ranged age 21-30 years with gestational age,≥ 37 weeks, multipara. Subjects were diagnosed with PE with proteinuria more than PE without proteinuria.The most maternal outcome is ICU treatment followed by HELLP syndrome, eclampsia and pulmonary edema then maternal death. The highest fetal death rate for babies with birth weight is LBW,with more normal APGAR scores

IQTISHODUNA ◽  
2020 ◽  
Vol 16 (1) ◽  
pp. 83-100
Author(s):  
Olin Lintang Pribadi

This study aims to determine the cause of the low market share of general engineering products at PT PAL Indonesia. Market share analysis is considered important in winning business competition. The study uses qualitative descriptive methods and subject data in the form of opinions, attitudes, experiences or characteristics of a person or group of people who are the research subjects or informants. Source of data used are primary data derived from informant interviews and secondary data derived from supporting documents relevant to the study. To find out the root of the problem using the technique of root causes analysis with the fishbone method and find alternative solutions to the problem with the Delphi method in the form of a questionnaire to the experts. The results of the study explained that the low market share of general engineering products is found in every indicator of fishbone, namely: machine, method, material, manpower, measurement and mother nature. And in the opinion of the experts there is no significant difference of opinion in providing alternative solutions to every problem on the fishbone indicator. So the company can be used in making policies.


2021 ◽  
Vol 12 (1) ◽  
pp. 50-59
Author(s):  
Nugroho Susanto

Turkish Ministry of Health estimated that 6.3% cases of COVID-19 fatality in April 2020 and 2.1% cases of COVID-19 mortality are associated with multi-factors. COVID-19 is very dangerous for moderate respiratory infection and has higher mortality compared to other diseases such as SARS-CoV-2. The study aims to compare case confirmation, mortality and compare incidence rate mortality between Indonesia and the world’s general situation. The study designs used a cross-sectional study with secondary data. The study population was people who have been diagnosed to covid-19 based on the website with URL: https://covid19.who.int/ and URL: https://covid19.kemkes.go.id/ for the period of March 2020 to November 2020. The Independent Variables are areas of disease i.e. Indonesia, Asia, and world area. Statistical analysis was performed using SPSS. Data were analyzed with ANOVA. Average of confirmatory covid-19 is 1891.65±1468.412 in Indonesia, 41146.94±34159.12 in Asia, and 211914.42±128689.95 according to WHO. The average mortality was 62.29±37.69 in Indonesia, 635.36±453.68 in Asia, and 5279.71±1540.41 according to WHO. The incidence mortality rate was 0.046±0.0326 in Indonesia, averaged 0.023±0.0157 in Asia, and averaged 0.035±0.0231 according to WHO. There was a significant difference in confirmatory case between Indonesia, Asia and WHO with p<0.001, a significant difference in mortality between Indonesia, Asia and WHO with p<0.001, and significant difference in incidence mortality between Indonesia, Asia, and Indonesia with p<0.001. The study was concluded that there are significant differences in confirmatory case, death, and incident mortality between Indonesia, Asia and WHO. Confirmatory case and mortality were higher in WHO and Asia when compared to Indonesia, but incidence mortality was high in Indonesia when compared to WHO and Asia.


2020 ◽  
Vol 4 (s1) ◽  
pp. 95-95
Author(s):  
Jailene Canales ◽  
Alison Weiss ◽  
Senu Apewokin

OBJECTIVES/GOALS: We previously reported that genetic polymorphisms in the beta-catenin gene (CTNNB) are associated with the development of Clostridiodes difficile colitis during autologous stem cell transplantation (https://www-ncbi-nlm-nih-gov.proxy.libraries.uc.edu/pubmed/29594489). To biological validate these findings, we sought to evaluate the development of chemotherapy-associated Clostridiodes difficile infections by assessing the effect of C.difficile toxin B (TcdB) and of using melphalan in beta-catenin protein expression in Caco2 cells. METHODS/STUDY POPULATION: To determine the effect of melphalan and/or C.difficile toxin B on expression of Beta-catenin from human gut epithelial cells: Adenocarcinoma cells (Caco-2) cells were seeded and allowed to grow into monolayersMonolayers were treated with PBS, TcdB, melphalan and/or TcdB + melphalan for 24 hours and then washed with PBSImmunofluorescence was measured on the monolayers to visualize three markers -DAPI-Nuclear Stain (blue),Actin-ccytoskeletal stain (red), B-Catenin (green)Analysis of images with ImageJ (NIH). Statistical analysis of the effect of TcdB and/or melphalan on β-catenin protein levels was determined by One-way ANOVA Cells stained with a primary anti-β catenin antibody and an Alexa-488 secondary antibody were evaluated by flow cytometry to quantify the effect of melphalan and/or C. difficile toxin B on Caco2 cells. RESULTS/ANTICIPATED RESULTS: Immunofluorescent intensity was higher in the control (PSS exposed) cells when compared to melphalan, TcdB and mephalan+TcdB exposed cells (p = 0.026, 0.004 and 0.049 respectively) DISCUSSION/SIGNIFICANCE OF IMPACT: A significant difference was seen in β catenin expression in Caco-2 monolayers exposed to TcdB and/or melphalan. These data support the a role of β-catenin in the pathophysiology of CDI during chemotherapy and support GWAS findings reporting a difference in CDI susceptibility based on β-catenin genotype.


Author(s):  
Sari Haslinur ◽  
Irwan Saputra ◽  
Dedy Syahrizal ◽  
Bakhtiar Bakhtiar ◽  
Said Usman

INA CBG’s rate is system of health financing packages from government based on cased and hospital services. Real tariff are the actual costs incurred by hospitals service based to local governments. During this time there are differences between INA CBGs rated and hospital rates. Hemophilia is a high-cost disease paid by INA CBGs. The aim of this study was to analyze the differences of INA CBGs and real rates in Hemophilia Patients at RSUDZA Banda Aceh. The research used quantitative analyticmethod. Data collection was carried out by taking secondary data from visits of hemophilia patients at RSUDZA in January-Desember 2019. The study population was all hemophilia patients in RSUDZA in 2019 with purpousive random sample of 100 people. There was a significant difference between INA CBGs rated and hospital rates rates in Hemophilia Patients at RSUDZA Banda Aceh.which indicated by p-value 0,000. Differences between INA CBGs and real rates of hospital are Rp.-431.095.538 or -25%. Differences of INA CBGs rated dan real rates causes’ hospital loss, but hospital needs to re-review the calculation of more efficient service cost to improve the quality of service.


JURNAL AGRICA ◽  
2020 ◽  
Vol 13 (1) ◽  
Author(s):  
Rifki Andi Novia ◽  
Ratna Satriani

This study aimed to determine the effect of agricultural land tenure status on rainfed lowland rice production in Banyumas Regency. One of the most important factors of production affecting the production of rainfed lowland rice is the land used. This study used  survey method by taking primary data and secondary data. Primary data obtained through a list of questions that have been prepared, while secondary data obtained from the relevant agencies. The sampling method is carried out by stratified random sampling. Each stratum of the sample is drawn with a total sample of 50 farmer respondents. Data were analyzed used one-way analysis of variance (One-way ANOVA). The results of this study indicated that the amount of rainfed lowland rice production in Banyumas District showed significant difference between farmers who were not owners and farmers who own land. Non-owner farmers get an average production yield greater than those of farmers who own rainfed lowland rice in Banyumas Regency.


2000 ◽  
Vol 15 (3) ◽  
pp. 231-234 ◽  
Author(s):  
I. García ◽  
F. Vizoso ◽  
A. Andicoechea ◽  
P. Fernandez ◽  
C. Suarez ◽  
...  

The aim of this study was to evaluate, by means of an immunoenzymatic assay, the membranous and cytosolic c-erbB-2 oncoprotein contents in primary tumors and in adjacent mucosa from gastric cancer patients. Fifty-two patients with primary gastric adenocarcinomas were enrolled in this prospective study. c-erbB-2 protein levels were significantly higher in membranous than in cytosolic samples, both in neoplastic tissues (median: 3602 vs 525 NHU/mg protein; p<0.0001) and in adjacent mucosa samples (median: 3174 vs 509 NHU/mg protein; p<0.0001). Nevertheless, there was a significant positive relation between membranous and cytosolic c-erbB-2 protein contents in both neoplastic tissue (p<0.001) and adjacent mucosa (p<0.001) samples. There was no significant difference in the membranous c-erbB-2 protein content between neoplastic tissues and adjacent mucosa samples. However, the cytosolic c-erbB-2 content was significantly higher in neoplastic tissues than in adjacent mucosa (p<0.05). Finally, the results did not show any significant correlations of these oncoprotein contents with patient characteristics, clinicopathologic parameters and overall survival of the study population.


2021 ◽  
Vol 5 (1) ◽  
pp. 18-28
Author(s):  
Dirvi Abbas ◽  
Indra Gunawan Siregar ◽  
Basuki

The purpose of this study is to determine the effect of corporate governance, company size, and leverage on the integrity of financial statements partially in essential industrial and chemical manufacturing companies listed on the Indonesia Stock Exchange (IDX) and using the 2013-2017 research period. The study population includes companies. Essential industrial and chemical manufacturing sectors listed on the Indonesia Stock Exchange for the period 2013-2017. The sampling technique was using the purposive sampling technique. Based on the predetermined criteria, a total sample of 7 companies was obtained. The type of data used is secondary data obtained from the Indonesia Stock Exchange website. The data analysis method used is a panel data regression analysis with the help of Eviews 9.0. Based on this research, it can be concluded that the independent commissioner has an effect, the audit committee on the integrity of financial statements, and leverage has no impact on the integrity of the financial statements.


2019 ◽  
Vol 103 (9-10) ◽  
pp. 435-442
Author(s):  
Hideki Kawamura ◽  
Susumu Shibasaki ◽  
Tadashi Yoshida ◽  
Tatsushi Shimokuni ◽  
Hideyasu Sakihama ◽  
...  

We compared laparoscopic gastrectomy for remnant gastric cancer (LRG) with open gastrectomy for remnant gastric cancer (ORG) to assess the safety and invasive nature of LRG. This study was a retrospective study. The study population consisted of 27 consecutive patients who underwent gastrectomy for remnant gastric cancer. Of these, 15 underwent ORG between January 2003 and April 2007, and 12 underwent LRG between May 2007 and January 2013. The operation time was not significantly different between the 2 groups. However, blood loss was significantly less in the LRG group than in the ORG group. No intraoperative blood transfusion was required. There was no significant difference in morbidity rate between the LRG (1/12, 8.3%) and ORG (4/15, 26.7%) groups, and no patients died in either group. Body temperature on postoperative day (POD) 7 (P = 0.034); systolic blood pressure on PODs 6 (P = 0.042) and 7 (P = 0.035); and heart rate on POD 7 (P = 0.049) were significantly lower in the LRG group than in the ORG group. No significant differences were observed in white blood cell count, or C-reactive protein and serum albumin levels between the groups. Serum total protein levels were significantly higher on POD 1 (P = 0.020), and the number of lymphocytes was significantly higher on POD 7 in the LRG group than in the ORG group (P = 0.036). Pain scores on POD 7 were significantly lower in the LRG group than in the ORG group (P = 0.033). LRG is a technically feasible and safe procedure.


2017 ◽  
pp. 30-50
Author(s):  
Darwis Tamba

The aim of this research, analyze the influence of cultural, social, personal and psychology of the buying decisions in Indomaret and analyzes of the four variables: cultural, social, personal and psychological variables which are the most dominant influence on buying decisions in Indomaret. Benefits study provides empirical evidence about the influence of cultural, social, personal and psychological on purchase decisions in Indomaret, provide knowledge to the public about cultural, social, personal and psychology of the buying decisions in Indomaret and contribute to the academic community about the importance of knowing the effect of factors cultural, social, personal and psychological on purchase decisions. The study population across the Faculty of Economics of the Catholic University of Santo Thomas North Sumatra ever shopped at Indomaret district of Medan Selayang while the study sample sebahagian the population can be considered representative. The total sample of 100 respondents, the type of data used primary and secondary data and data collection tools through questioner and documentation. Data analysis tool used regression. The results showed the multiple linear regression equation: KM = 3.503 + 0,122FBu 0,016FSo + + + 0,337FPsi 0,246FPri. The equation shows that cultural factors, social factors, individual factors, and psychological factors have a positive influence on the purchase decision will be positive. By F test, showing that the test results simultaneously (Test F) note the value F = 15.672 significance of 0.000


VASA ◽  
2017 ◽  
Vol 46 (6) ◽  
pp. 484-489 ◽  
Author(s):  
Tom Barker ◽  
Felicity Evison ◽  
Ruth Benson ◽  
Alok Tiwari

Abstract. Background: The invasive management of varicose veins has a known risk of post-operative deep venous thrombosis and subsequent pulmonary embolism. The aim of this study was to evaluate absolute and relative risk of venous thromboembolism (VTE) following commonly used varicose vein procedures. Patients and methods: A retrospective analysis of secondary data using Hospital Episode Statistics database was performed for all varicose vein procedures performed between 2003 and 2013 and all readmissions for VTE in the same patients within 30 days, 90 days, and one year. Comparison of the incidence of VTEs between procedures was performed using a Pearson’s Chi-squared test. Results: In total, 261,169 varicose vein procedures were performed during the period studied. There were 686 VTEs recorded at 30 days (0.26 % incidence), 884 at 90 days (0.34 % incidence), and 1,246 at one year (0.48 % incidence). The VTE incidence for different procedures was between 0.15–0.35 % at 30 days, 0.26–0.50 % at 90 days, and 0.46–0.58 % at one year. At 30 days there was a significantly lower incidence of VTEs for foam sclerotherapy compared to other procedures (p = 0.01). There was no difference in VTE incidence between procedures at 90 days (p = 0.13) or one year (p = 0.16). Conclusions: Patients undergoing varicose vein procedures have a small but appreciable increased risk of VTE compared to the general population, with the effect persisting at one year. Foam sclerotherapy had a lower incidence of VTE compared to other procedures at 30 days, but this effect did not persist at 90 days or at one year. There was no other significant difference in the incidence of VTE between open, endovenous, and foam sclerotherapy treatments.


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