scholarly journals Development Of Caulis Extract (Tinospora Crispa (L.) Hook. F. & Thomson As Plasmodium In Preparations Tablets

2018 ◽  
Vol 9 (1) ◽  
pp. 6-15
Author(s):  
Patimah Patimah ◽  
Junie Suriawati ◽  
Siti Rahayu Rahmawati
Keyword(s):  
Raw Materials ◽  
Wild Plant ◽  
Wet Granulation ◽  
Materials Testing ◽  
Quality Test ◽  
Physical Quality ◽  
Size Uniformity ◽  
Tablet Dosage

Brotowali (Tinospora crispa (L.) Hook. f. Thomson is a wild plant & in the Woods, fields or planted page near the fence, and the usual planted as medicinal plants. The entire plant (roots, stems, and leaves) has a bitter taste that can be used as a traditional medicine as Plasmodium. This research aims to make the tablet dosage of Caulis extract with gelatin Binder and polivenilpirolidon materials that meet the requirements of the physical quality of a tablet that is acceptable. Prior to the manufacture of tablets do extract raw materials testing which includes the determination of the levels of ash, determination of microbial impurities, testing the determination of aflatoxin levels of impurities, the determination of the levels of pesticide residues, the determination of the level of heavy metal impurities. Caulis extract tablet manufacture is made with two formula with each different binding materials, namely formula I used gelatin formula II 5% and 5% use polivinilpirolidon. The methods used in the manufacture of Caulis extract tablets using a wet granulation method. Granul tested his physical properties obtained covering moist, flow properties, compressibility granule. Tablets obtained physical quality test performed which include uniformity of weight, hardness, size uniformity, compressibility, and the crushed tablets. The data obtained were analyzed statistically using SPSS 15.0 for windows program namely testing T-Test with a 5% confidence. The results showed that the two formula tablets with the uniformity of weight, hardness, size uniformity, compressibility, and the time crushed tablet that meets the requirements of the physical quality of a good tablet. The conclusions of this research are extracted Caulis tablet can be created that meets the requirements of physical quality test tablet.

scholarly journals Uji Mutu Fisik Metoklopramid HCl Tablet Chewable dengan Variasi Jenis Pengisi sebagai Diluent menggunakan Metode Granulasi Basah

2021 ◽  
Vol 1 (2) ◽  
pp. 76-85
Author(s):  
Umi Latifiana ◽  
Deny Budi Legowo ◽  
Erna Fitriany ◽  
Andri Priyoherianto ◽  
Muhammad Novianto Ainul Huri
Keyword(s):  
New Product ◽  
Wet Granulation ◽  
Test Results ◽  
Quality Test ◽  
Disintegration Time ◽  
Chewable Tablet ◽  
Physical Quality ◽  
Chewable Tablets ◽  
Tablet Hardness

Metoclopramide HCl are used to reduce vomiting and nausea. The availability on the market in the form of tablet, syrup and injection. Patient tend to prefer take drugs by oral use because it was easier. Chewable tablet is the new product as the alternative ways to treatment children and adult patient who had difficulity problem of swallowing drugs. Objectives: This research aims to formulate the chewable metoclopramide HCl tablets using diluent variations to get a better physical quality test. Chewable tablets of metoclopramide HCl are made using diluent variations, they are mannitol, sucrose, lactose. Formula I mannitol, formula II sucrose, and formula III lactose. Chewable tablet preparations are made by the wet granulation method. Data collection was performed on physical characteristics including organoleptic, weight uniformity, uniformity of size, tablet hardness, tablet fragility, disintegration time, metoclopramide HCl levels. Physical quality test results were statistically analyzed to determine the effect of variations in the diluent on the characteristics of chewable tablets. The results of this research have an influence on the physical quality and uniformity of contents of various types of diluent variations between each formulation. In this research, fillers have an important role in the preparation of chewable metoclopramide tablets to determine the physical quality of the tablets and the uniformity of their contents. The variation of diluent that gives better results is mannitol. This is because formulas that use mannitol have uniformity in content that meets the requirements, faster disintegration time, and physical quality of tablets that still meet the requirements, when compared to the first and second formulations. The variation of diluent that gives better results is mannitol.

scholarly journals The formulation of white oyster mushroom (Pleurotus ostreatus (Jacq.) P. Kumm) as natural flavoring and the quality test in temperature and drying time variations

2021 ◽  
Vol 922 (1) ◽  
pp. 012054
Author(s):  
S Sadli ◽  
S Saleha ◽  
D Fiana ◽  
M Misrahanum
Keyword(s):  
Low Temperatures ◽  
Pleurotus Ostreatus ◽  
Raw Material ◽  
Quality Test ◽  
Drying Time ◽  
Test Parameters ◽  
Time Variations ◽  
Oyster Mushrooms

Abstract The determination of the drying temperature and time depends to the characteristic of the mushrooms. The use of low temperatures causes the mushrooms to not fully ripen, if the temperature is too high the protein contained in the mushrooms can be denatured and drying too long will change the color of the mushrooms to brown and change its taste. Research on the processing of oyster mushrooms as a raw material for natural flavoring, it is carried out to determine the quality flavoring produced through a descriptive test of the test parameters, color, aroma, taste and texture by variations the temperature 60¼C and 70¼C in drying time 6, 7 and 8 hours. The results of descriptive test of the sixth color of the flavoring have an intensity of attractive colors are light brown; Descriptive taste test F1, F2 and F5 have the intensity of the taste is rather pleasant, the umami is weak while F3, F4 and F6 have taste is quite good, umami tastes; Descriptive test of the six flavoring textures has a good intensity and; Descriptive test of the sixth aroma of flavoring has a slightly fragrant aroma intensity, the aroma of the material is not too smelly. The conclusion of the research is that temperature and drying time do not affect quality of color, aroma and texture. However, they affect the taste where the temperature 60¼C for 8 hours and a temperature of 70¼C within 7 and 8 hours have enough delicious taste with tasteful umami.

The issue of "oil shrinkage" during the compounding of oils in the processes of production, collection, preparation and transportation of hydrocarbon raw materials

2021 ◽  
pp. 104-113
Author(s):  
O. P. Deryugina ◽  
E. A. Trapeznikov
Keyword(s):  
Raw Materials ◽  
Raw Material ◽  
Colloidal System ◽  
Main Pipelines ◽  
Different Types ◽  
Preliminary Study ◽  
The Stability ◽  
Mixed Oil

The article discusses the issue of industrial compounding, which improves the quality of the raw materials supplied to the main pipelines. Compounding from "to compound" (English) - to mix. When mixing different types of oil obtained, "incompatibility" is possible, which is expressed in the precipitation of a solid sediment and violation of the stability of the colloidal system and due to the differing properties of oils. Attention to this problem is due to the tightening of requirements for the quality of raw materials that must comply with modern standards. The article discusses the causes of the problem of "incompatibility" of oil during compounding and effective ways of solving it, substantiates the need for a preliminary study of the properties of mixed oil in order to identify possible incompatibility of various types of oil. The standard tests for determination of incompatibility indices characterizing the ability of raw materials to mix are considered. The article substantiates the need to develop methods for diagnosing the incompatibility of oils as the most important task of modern chemical science, the solution of which will improve the quality of the raw material obtained and solve many technological problems in the compounding process.

scholarly journals Determination of the transfer step of the ore chute while mining the technogenic deposit of the bulk type

2020 ◽  
Vol 166 ◽  
pp. 02004
Author(s):  
Volodymyr Peregudov ◽  
Ihor Hryhoriev ◽  
Serhii Joukov ◽  
Yulian Hryhoriev
Keyword(s):  
Raw Materials ◽  
Mining Industry ◽  
Process Conditions ◽  
Geological Conditions ◽  
Scientific Task ◽  
Technogenic Deposit ◽  
Mining Works ◽  
The Cost

Further development of the open mining works on the domestic enterprises will be accompanied by the worsening of mining-geological conditions and declining of the quality of iron ore raw materials. In the same time, the accumulated mining wastes, that can make the technogenic deposits, pass into one of the important sources of the mineral raw materials. Taking into account this thing, the development and implementation of the modern technological circuits of the technogenic deposit development is an actual calling for mining industry, and determination and optimization of process conditions of the technogenic deposit development – is the scientific task of this publication. The obtained results of studies of the optimum step value of the ore chute transfer during the technogenic deposit development can be used by design organizations and mining enterprises for designing works. The obtained methodology and the proposed mathematical dependencies will reduce the cost of mining of the technogenic deposit due to the reasonable timely transfer of the open ore chute.

scholarly journals Determination of the comprehensive indicator of pastille with the use of multi-component fruit-berry paste

2021 ◽  
Vol 3 (3(59)) ◽  
pp. 46-49
Author(s):  
Kateryna Kasabova ◽  
Nataliа Shmatchenko ◽  
Aleksey Zagorulko ◽  
Andreii Zahorulko
Keyword(s):  
Ascorbic Acid ◽  
Chemical Composition ◽  
Raw Materials ◽  
Control Sample ◽  
Comprehensive Assessment ◽  
Biologically Active ◽  
Human Need ◽  
Pectin Substances

The object of research in this work is the technology of pastille with the addition of multicomponent fruit and berry paste. Pastille are becoming more and more popular in the world for all segments of the population. Usually, the main ingredients for their manufacture are fruit raw materials, a structurant and egg white, therefore, the products contain practically no fat and have a low calorie content. It is proposed to replace 75 % of traditional applesauce in the recipe with a multicomponent fruit and berry paste made from apples, cranberries, hawthorn. It was found that such a composition makes it possible to obtain products with an increased content of pectin substances, ascorbic acid, polyphenols, including anthocyanins, catechins and flavonols. The work is aimed at studying the application of the principles of qualimetry to determine a complex indicator of the quality of pastille For this, the organoleptic and physicochemical indicators of the quality of the developed pastille were taken from previous studies and the chemical composition was determined and the content of biologically active substances was calculated relative to the average daily human need. The content of pectin substances in new products increases 1.7 times and satisfies the average daily human need by 18.2 %. The content of ascorbic acid is 4.2 times higher, which is 20.5 % of the average daily human need, and polyphenols 3.2 times higher – 579.0 %. The data obtained make it possible to consider the developed product functional. The next step was to determine the complex indicator of products by the qualimetric method. For a more complete disclosure of product properties, a structure of pastille quality indicators has been developed – a «tree of properties». Thus, the comprehensive assessment of the quality of the control sample corresponds to the indicator «good» (0.66), while the integrated assessment of pastille with multicomponent paste corresponds to the indicator «very good» (0.98). On the basis of organoleptic, physicochemical indicators and chemical composition of products, it was established that the indicator of a comprehensive assessment of the quality of a pastille with a multicomponent paste, taking into account all group indicators, is 48 % higher compared to the control.

scholarly journals Bees: bioindicators of the environment

2020 ◽  
Author(s):  
Iryna Kovalchuk
Keyword(s):  
Heavy Metals ◽  
Heavy Metal ◽  
Raw Materials ◽  
Literature Information ◽  
Heavy Metals Accumulation ◽  
Systems Research ◽  
Metals Accumulation ◽  
Methodological Approaches

It is well-known that melliferous bees are the most sensitive indicators of ecologic conditions of natural environment. Researches in recent years show that bees and bee products can accumulate selectively some heavy metals, radioactive substances, pesticides and other polluters. Scales of heavy metals accumulation on the territory of Ukraine, as toxins of technologic origin unfortunately increase. Environmental pollution by heavy metals leads to their accumulation in plant and animal raw materials and production, consequently their quality decreases. It was proved that apiary accommodation in heavy metal polluted territories leads to their accumulation in pollen, honey bee-comb and wax. But the questions concerning study of peculiarities of sources, ways of pollution and heavy metals content in bee products are not enough lightened, and that was the purpose of our work. Generalized we present in literature information and results of our researches about the use of bees and bee products in quality of bioindicator contamination of environment by heavy metals. Dependence of content of heavy metals is set in the organism of bees in relation intensity of greening to contamination of environment. It is marked on the necessity of lead through of systems research in relation to determination of content of heavy metals in fabrics of bees and bee products with the purpose of search of new methodological approaches for authentication these toxicant of objective environment of contamination and him apimonitoring. Methodological elements of the researches of regularities of heavy metals and lipids content in the tissues of different anatomic sections of the organism and bee products were elaborated.

scholarly journals Physical quality of seeds of Moquiniastrum polymorphum

2019 ◽  
Vol 79 (1) ◽  
pp. 63-69 ◽  
Author(s):  
J. C. T. Faria ◽  
L. A. Melo ◽  
C. R. M. Assumpção ◽  
G. E. Brondani ◽  
T. B. Breier ◽  
...  
Keyword(s):  
Heavy Fraction ◽  
External Evaluation ◽  
Physical Quality ◽  
X Ray ◽  
Internal Morphology ◽  
Combined Use ◽  
Heavy Fractions ◽  
Filled Seeds

Abstract This study aimed to analyze the physical properties of the seeds of Moquiniastrum polymorphum when processed by mini-SAS, X-ray and seed blower systems. The seeds were purchased from Seeds Caiçara, located in Penápolis-SP. After purchase, the seed lot was characterized by standard tests. In the X-ray test the seeds were classified according to their internal morphology as filled, unfilled or malformed. The seed blower was set at six opening settings, resulting in light and heavy fractions. The evaluations were performed by weighing the seeds that remained in the blower (heavy fraction) and by the amount of filled seeds indicated by the X-ray test. The germination tests were composed of four replicates of 50 seeds. The mini-SAS was used for external evaluation. It was concluded that the combined use of the seed blower and the X-ray test was efficient for the evaluation and determination of the physical quality of the seeds of M. polymorphum. The seed blower at opening settings 5 resulted in the best lot quality. The external parameters were not able to qualitatively evaluate the seeds of M. polymorphum.

scholarly journals Investigation of safety and mineral composition of fresh petioles of Аrctium lappa L

2021 ◽  
Vol 296 ◽  
pp. 07010
Author(s):  
Olga Viktorovna Deryusheva
Keyword(s):  
Mineral Composition ◽  
Raw Materials ◽  
Wild Plants ◽  
Wild Plant ◽  
Wild Mushrooms ◽  
Plant Raw Materials ◽  
Regulatory Documents ◽  
Negative Effect ◽  
Quality Of Products

The range of food stuffs having a rich composition of useful substances can be greatly enhanced by using a great variety of wild plants growing in Siberia. Apart from familiar widely used wild mushrooms, berries and other wild plants a biennial herbage plant, namely, great burdock can be used. Precise requirements to safety of wild plants growing in Russia are not available in regulatory documents. This makes it much more difficult to pass the procedures of confirming the conformity of products. This also has a negative effect on the processes of harvesting, storage, processing and transportation of wild plant raw materials. The key goal of testing the quality of products is to ensure safety of food stuffs. This goal can be achieved by further study of wild plants and by establishing precise standards of safety.

scholarly journals INFLUENCE OF APPROACHES TO ISOLATION OF ANIMAL BIOACTIVE SUBSTANCES ON ANTIMICROBIAL ACTION

2018 ◽  
Vol 3 (3) ◽  
pp. 27-35
Author(s):  
Ekaterina A. Lukinova ◽  
Elena A. Kotenkova ◽  
Ekaterina K. Polischuk
Keyword(s):  
Raw Materials ◽  
Antimicrobial Effect ◽  
Animal Origin ◽  
Acid Extraction ◽  
Bioactive Substances ◽  
Antimicrobial Substances ◽  
Natural Substances ◽  
Quality Of Food

This article highlights the problem of the use of chemical preservatives in the food industry. The prospects of implementation natural substances with an antimicrobial effect for prolonging shelf life and improving the quality of food products are also discussed. Methods for isolating of antimicrobial substances from epithelial and mucous tissues of animal origin are proposed, taking into account the minimization of losses of their biological activity in accordance with the structure of protein-peptide molecules. Based on the results of the determination of antimicrobial activity against Listeria monocytogenes, Staphylococcus aureus and Pseudomonas aeruginosa using flow cytometry, stains Eva Green and PI, the most promising raw materials were determined and the feasibility of using weakly acid extraction followed by trypsinolysis for releasing antimicrobial substances from preprotein molecules and ultrafiltration for purification from high-molecular compounds were investigated.

scholarly journals Methodological Approach to Determination of Priorities in Ecological Estimation of the Russian Territories

2020 ◽  
Author(s):  
I.G. Spiridonov ◽  
E.N. Levchenko ◽  
D.S. Klyucharev
Keyword(s):  
Environmental Impact ◽  
Raw Materials ◽  
Mineral Exploration ◽  
Methodological Approach ◽  
Federal District ◽  
Environmental Safety ◽  
Rare Metal ◽  
Urban Environments

This paper assesses the main types of environmental impact caused by mineral exploration and mining. The ecological situation due to the extraction and processing of mineral raw materials in the mining regions, as well as the environmental impact of accumulated mining waste are shown. The results of environmental monitoring of the quality of the industrial urban environments of the Russian Federation are also presented. Based on the analysis of the database of existing man-made formations, including those produced from the rare metal deposits, the maps of their distribution over the territory of Russia as a whole and the territory of the Ural Federal District are compiled. The ranking of man-made deposits and formations by their impact on environmental elements has been performed. Keywords: mining, industrial waste, heavy metals, ecosystem pollution, environmental safety

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