scholarly journals Selected toxicological aspects of honey

2020 ◽  
Vol 2 (4) ◽  
pp. 95-99
Author(s):  
Katarína Fatrcová Šramková ◽  
Miroslava Kačániová

The aim of the present review was to analyze grayanotoxin and its healthy and poisoning effect to human health according to available resources of literature. Plants contain many compound components which can be categorized as "medical" or "poisonous" depending on their effects to human body.  There are also secondary products derived from plants, such as honey, which can contain many chemical compounds with medicinal or poisonous effects depending on their concentration and application. Many plants of the Ericaceae family, Rhododendron, Pieris, Agarista and Kalmia, contain diterpene grayanotoxins. The consumption of grayanotoxin containing leaves, flowers or secondary products as honey may result in intoxication specifically characterized by dizziness, hypotension and atrial-ventricular block.

Molecules ◽  
2021 ◽  
Vol 26 (22) ◽  
pp. 6940
Author(s):  
Eleomar de O. Pires ◽  
Francesco Di Gioia ◽  
Youssef Rouphael ◽  
Isabel C. F. R. Ferreira ◽  
Cristina Caleja ◽  
...  

Edible flowers are becoming very popular, as consumers are seeking healthier and more attractive food products that can improve their diet aesthetics and diversify their dietary sources of micronutrients. The great variety of flowers that can be eaten is also associated with high variability in chemical composition, especially in bioactive compounds content that may significantly contribute to human health. The advanced analytical techniques allowed us to reveal the chemical composition of edible flowers and identify new compounds and effects that were not known until recently. Considering the numerous species of edible flowers, the present review aims to categorize the various species depending on their chemical composition and also to present the main groups of compounds that are usually present in the species that are most commonly used for culinary purposes. Moreover, special attention is given to those species that contain potentially toxic or poisonous compounds as their integration in human diets should be carefully considered. In conclusion, the present review provides useful information regarding the chemical composition and the main groups of chemical compounds that are present in the flowers of the most common species.


2019 ◽  
Vol 20 (7) ◽  
pp. 756-762 ◽  
Author(s):  
Aditi Kaushik ◽  
Manish Kaushik ◽  
Viney Lather ◽  
J.S. Dua

An emerging crisis of antibiotic resistance for microbial pathogens is alarming all the nations, posing a global threat to human health. The production of the metallo-β-lactamase enzyme is the most powerful strategy of bacteria to produce resistance. An efficient way to combat this global health threat is the development of broad/non-specific type of metallo-β-lactamase inhibitors, which can inhibit the different isoforms of the enzyme. Till date, there are no clinically active drugs against metallo- β-lactamase. The lack of efficient drug molecules against MBLs carrying bacteria requires continuous research efforts to overcome the problem of multidrug-resistance bacteria. The present review will discuss the clinically potent molecules against different variants of B1 metallo-β-lactamase.


2020 ◽  
Vol 16 ◽  
Author(s):  
Ramazan Akçan ◽  
Halit Canberk Aydogan ◽  
Mahmut Şerif Yıldırım ◽  
Burak Taştekin ◽  
Necdet Sağlam

Background/aim: Use of nanomaterials in the healthcare applications increases in parallel to technological developments. It is frequently utilized in diagnostic procedures, medications and in therapeutic implementations. Nanomaterials take place among key components of medical implants, which might be responsible for certain toxic effects on human health at nano-level. In this review, nanotoxicological effects, toxicity determination of nanobiomaterials used in human body and their effects on human health are discussed. Material and Method: A detailed review of related literature was performed and evaluated as per nanomaterials and medical implants. Results and Conclusion: The nanotoxic effects of the materials applied to human body and the determination of its toxicity are important. Determination of toxicity for each nanomaterial requires a detailed and multifactorial assessment considering the properties of these materials. There are limited studies in the literature regarding the toxic effects of nanomaterials used in medical implants. Although these implants are potentially biocompatible and biodegradable, it is highly important to discuss nanotoxicological characteristics of medical implant.


Author(s):  
Rohit Rastogi ◽  
Mamta Saxena ◽  
Mayank Gupta ◽  
Akshit Rajan Rastogi ◽  
Pradeep Kumar ◽  
...  

From ancient times, humans are striving for being healthy and to live with mental peace with family and society. In the previous centuries also, some manmade and mostly natural disasters have disturbed the pace of human life. There have been times when the whole human race has been in terror, danger, and utmost worry. The electrical gadgets also have made the human life comfortable, but also machines have dominated its consciousness. The stress, aggression, depression, and many more issues are also showing presence in all our lives. The chapter is a trial to establish the effect of yagna and mantra science over human calmness and its effect on human health irrespective to gender and age. The article also elaborates the effect of Sanskrit sound and mantra chanting on emission of radiations from electronic gadgets. It also presents the effect of spiritual practices on the human body and soul after the terror, stress, grief created due to COVID-19.


Author(s):  
N. L. Lukyanchikova ◽  
V. A. Skryabin ◽  
K. A. Tabanyukhov

The paper analyzes the literature on the therapeutic and prophylactic effects of components of secondary products of processing of rye and wheat – dietary fiber and phenolic compounds – on human health. A special role is played by soluble arabinoxylans and xylooligosaccharides associated with ferulic acid, which have prebiotic, antioxidant and immunomodulatory properties. Experimental and epidemiological studies have shown that the inclusion of cereal bran in the diet has a positive effect on human health and helps to reduce the risk of diseases associated with the Western type of diet – atherosclerosis, second type diabetes, and various types of oncology.


2021 ◽  
Vol 12 (3) ◽  
pp. 81-86
Author(s):  
Herasymenko A.S. ◽  
◽  
Kultenko V. P. ◽  

Ethical dimensions of biotechnology problems are studied, in particular: ethics of use of embryonic stem cells in science and medicine; the responsibility of researchers for the consequences of their actions; the ethics of using animals in biotechnological research to solve human problems and ensure human health; the limits of human intervention in the genome of living beings; problems of maintaining the balance of the ecosystem; moral and legal status of the embryo, which is used as a resource material in biotechnological research. The attitude of different religions to biotechnological research and experiments with embryonic stem cells is also considered. The question of the impossibility of obtaining economic benefits from the human body, including the unborn and its parts, is becoming more acute.


Author(s):  
Mojtaba Arjomandi ◽  
*Hamid Shirkhanloo

Heavy metals are vital and necessary in our daily lives. Moreover, if the amounts of heavy metals are more than the acceptable amounts (mentioned by WHO) in soil, water, and air, indeed, they cause a lot of diseases in human bodies. Therefore, monitoring and measuring the amounts of heavy metals that are arduous and difficult are so important. In this review paper, a lot of studies that have been carried out on the determination and quantification of heavy metals in human bodies, soil, and water are considered. Moreover, the effect of toxicity of each heavy metal on human health is assessed. According to WHO, EPA, NIOSH, ACGIH, and clinical chemistry, the determination of heavy metals such as Cd, Pb, Zn, Hg, Cu, Mn is very important in the human body and Environmental matrixes. 


Author(s):  
Yuanzhi Fu ◽  
Liuliu Wu ◽  
V.I. Trotsenko ◽  
H.O. Zhatova

Cadmium pollution in soil is a long-term and urgent problem, which directly affects the edible value of sunflower and winter wheat and may cause harm to human health. Breeding new varieties with low cadmium accumulation can effectively reduce the content of this element in seeds and fundamentally solve the risk of cadmium entering the human body through seeds and oil. In this paper, the method and significance of breeding sunflower and winter wheat with low cadmium accumulation  were discussed.


2021 ◽  
Vol 68 (1) ◽  
Author(s):  
R. Jannathulla ◽  
O. Sravanthi ◽  
H. Imran Khan ◽  
H. Syed Moomeen ◽  
A. Gomathi ◽  
...  

Aquaculture serves as a sustainable source of good quality wholesome food and major input is feed. In recent years, considerable quantities of plant sources have been attempted for inclusion in shrimp feed, due to high demand and high cost of fishmeal. Plant-based ingredients are in general poor in attractability and palatability to aquatic species compared to marine sources. It is desirable to develop an economical and nutritious feed that is attractive and palatable for ensuring reduction of feed wastage. Chemoattractants nowadays are unavoidable in commercial shrimp feeds and are included either individually or in combination. The present review revealed that the various marine sources, in particular krill meal would be more effective for aquatic species, compared to those derived from vegetable origin and chemical compounds. In addition to acting as a feed attractant, marine sources serve as a potential fishmeal substitute due to their rich nutritional composition. However, certain biogenic amines present in these marine-based ingredients need to be examined before their use, since these amines when present in high concentrations reduces feed intake by producing undesirable odour. Use of a combination of chemoattractants would give a better effect, rather than using them individually and compounds from plant origin have limited beneficial effects. The present review concludes that incorporation of chemoattractants would be beneficial in formulation of enriched and economical feeds with better attractability and palatability. The selection of suitable attractant and their supplementation at correct proportion is significantly more important to avoid undesirable effects in cultured shrimp. Further field-based research is needed to predict the actual effects of chemoattractants on farmed shrimp and to provide a sustainable base for the expansion of shrimp aquaculture sector, by reducing feed wastage.


2020 ◽  
Vol 10 (5) ◽  
pp. 285-296
Author(s):  
Swapnali Chetia ◽  
Gaurab Borah

Abstract Δ9-tetrahydrocannabinol (THC) of cannabis is the main psychoactive component which is a global significant concern to human health. Evaluation on THC reported its drastic effect on the brain dopaminergic (DAergic) system stimulating mesolimbic DA containing neurons thereby increasing the level of striatal DA. Cannabidiol (CBD), with its anxiolytic and anti-psychotic property, is potent to ameliorate the THC-induced DAergic variations. Legal authorization of cannabis use and its analogs in most countries led to a drastic dispute in the elicitation of cannabis products. With a recent increase in cannabis-induced disorder rates, the present review highlighted the detrimental effects of THC and the effects of CBD on THC induced alterations in DA synthesis and release. Alongside the reported data, uses of cannabis as a therapeutic medium in a number of health complications are also being briefly reviewed. These evaluated reports led to an anticipation of additional research contradictory to the findings of THC and CBD activity in the brain DAergic system and their medical implementations as therapeutics. Graphic Abstract


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