EVALUATION OF THE EFFECTIVENESS OF THERAPEUTIC AND PREVENTIVE MEASURES OF DYSBIOSIS IN DENTAL PRACTICE

Author(s):  
Жанна Владимировна Вечеркина ◽  
Наталья Александровна Шалимова ◽  
Наталия Владимировна Чиркова ◽  
Елена Анатольевна Андреева ◽  
Марина Николаевна Бобешко

Увеличивающаяся тенденция нуждаемости пациентов использования несъемных, съемных зубных протезов, ортодонтических и челюстно-лицевых апппаратов, наблюдающаяся в последние годы, сопряжена с многими проблемами. Использующиеся в практике ортопедической стоматологии зубные протезы и аппараты оказывают побочное действие на слизистую оболочку полости рта (механическое, химико-токсическое, сенсибилизирующее), что приводит к нарушению биоценоза, чрезмерному росту патогенных микроорганизмов и увеличению числа дрожжевых колоний. Установлено также, что при использовании адгезивных препаратов для улучшения фиксации съемных протезов статистически достоверно увеличивается число дрожжевых колоний при количественном посеве по сравнению с контрольной группой пациентов. Еще более сложная ситуация наблюдается у пациентов, уже имеющих хроническое нарушение соотношения нормальной и условно - патогенной микробиоты и нуждающихся в протезировании съемными пластиночными протезами. Эти пациенты, как правило, имеют неудовлетворительную гигиену полости рта и тяжелую сопутствующую патологию, чаще всего сахарный диабет или дисбактериоз ЖКТ. В настоящее время получены убедительные данные о важной роли иммунных нарушений в патогенезе развития кандидоинфекции и антифунгальной резистентности. В частности, дисфункции клеточного звена иммунной системы, что способствует хроническому, рецидивирующему и зачастую торпидному к терапии течению заболевания. Это, в свою очередь, требует выполнения научных исследований в направлении коррекции состояния микрофлоры ротовой полости пользующихся ортопедическими конструкциями. Данная обзорная работа посвящена актуальным на сегодняшний день вопросам применения пре-, пробиотических культур и синбиотиков в комплексном лечении больных с дисбиотическим изменением полости рта, пользующихся ортодонтическими конструкциями, лечебно-диагностическими аппаратами. Целью работы стал всесторонний анализ проблемы целесообразности и эффективности использования вышеназванных средств с точки зрения этиопатогенеза дисбиоза в полости рта The increasing trend of patients ' need to use non-removable, removable dentures, orthodontic and maxillofacial devices, observed in recent years, is associated with many problems. Dental prostheses and devices used in the practice of orthopedic dentistry have a side effect on the oral mucosa (mechanical, chemical-toxic, sensitizing), which leads to a violation of the biocenosis, excessive growth of pathogenic microorganisms and an increase in the number of yeast colonies. It was also found that the use of adhesive preparations to improve the fixation of removable prostheses statistically significantly increases the number of yeast colonies during quantitative seeding compared to the control group of patients. An even more difficult situation is observed in patients who already have a chronic violation of the relationship between normal and opportunistic microbiota and need prosthetics with removable plate prostheses. These patients usually have poor oral hygiene and severe comorbidities, most often diabetes mellitus or gastrointestinal dysbiosis. Currently, there is strong evidence of the important role of immune disorders in the pathogenesis of Candida infection and antifungal resistance. In particular, dysfunction of the cellular link of the immune system, which contributes to the chronic, recurrent and often torpid to therapy course of the disease. This, in turn, requires scientific research in the direction of correlation of the state of the oral microflora using orthopedic structures. This review is devoted to current issues of the use of pre - probiotic cultures and synbiotics in the complex treatment of patients with dysbiotic changes in the oral cavity, using orthodontic structures, medical and diagnostic devices. The aim of the work was a comprehensive analysis of the problem of expediency and effectiveness of the use of the above-mentioned means, from the point of view of the eiopathogenesis of dysbiosis in the oral cavity

2018 ◽  
Vol 5 (6) ◽  
Author(s):  
Marjan Zare ◽  
Zaher Khazaei ◽  
Soghrat Faghihzadeh ◽  
Shohreh Jalaie ◽  
Malihe Sohrabivafa

Background: Estimating total, direct, and indirect effects of causal variables on outcome variables can be done through proposed mediator guides on causal pathways. This can improve the efficiency of diagnostic efforts done by clinicians. In this study, the relationship between Sulfur Mustard and Xerosis was investigated, specifically with respect to the role of Hemato_4, Hemato_5, Hemato_9, and Biochem_20 biomarkers as mediators. Methods and Results: This was a historical cohort study (in Sardasht, Iran) which consisted of 492 subjects; 129 subjects were not exposed to Mustard Gas (control group) and 363 subjects were exposed to it (case group). Mediation models along with bootstrap method were used to evaluate the mediator validity of Hemato_4, Hemato_5, Hemato_9, and Biochem_20 on the relationship between Sulfur Mustard and Xerosis. The direct effects of Sulfur Mustard, via Hemato_4 and Hemato_9, on Xerosis were also significant (P<0.05 for each). However, there was no significant effects mediated by Hemato_5 or Biochem_20 (P>0.05 for each). While there were non-significant indirect effects of Sulfur Mustard on Xerosis by these latter biomarkers (P>0.05 for each), the first two biomarkers were, indeed, partial mediators. Conclusion: Sulfur Mustard can affect Xerosis through several single immune biomarker. However, as an intervention, sulfur mustard should affect several biomarkers through various mechanisms. Therefore, effects through multiple mediators, instead of single ones, may be more rational in the treatment strategy for xerosis.  


Asian Studies ◽  
2015 ◽  
Vol 3 (1) ◽  
pp. 129-144 ◽  
Author(s):  
Kristýna VOJTÍŠKOVÁ

 According to some thinkers, in the 21st century, the Japanese society is facing a crisis of values. The postmodern approach to the individual and society may be one of the causes of this problem. In this point of view, an inadequate grasp of the relationship between the individual and the society seems to play an important role. The problem of this relationship was elaborated by the early 20th century philosopher Watsuji Tetsurō who endeavoured to re-define the role of an individual in the society. This paper attempts to examine the contemporary problem of Japanese identity from the perspective of Watsuji’s conception of interpersonal relationships. 


1970 ◽  
Vol 117 (539) ◽  
pp. 397-403 ◽  
Author(s):  
R. S. Ferguson ◽  
M. W. P. Carney

There is a body of opinion which regards psychiatrically ill individuals, or at least one great class or subdivision of them, as suffering primarily from disturbances in personal relationships and social interaction processes generally. Sullivan, Horney and Fromm have made the most significant theoretical contributions to this subject, and empirical applications have been reported by Balint (1957), Maxwell Jones (1968), Rapoport (1960) and Laing (1961). These writers have at least this in common, that they take the point of view that since the pathology of the illness lies in social relationships the fundamental treatment process must lie there also—must, in fact, consist of re-experiencing social interaction within a therapeutic re-educative framework. In the past attention has been directed principally to the doctor-patient relationship as a heuristic model of social interaction, but Rapoport has extended the operational range of significant interaction to include all staff-patient, staff-staff and patient-patient encounters. As the recent Subcommittee of the Central Health Services Council has pointed out (1968), little has been written of the nurse as therapist, but a considerable literature has accumulated concerning the role of the social worker or caseworker or counsellor (e.g. Halmos, 1965). Halmos investigates the nature of such relationships, and finds therapeutic utility to be unrelated to intellectual skills. The therapeutic process is adjudged to lie in the relationship, true enough, but the essential qualities have more to do with the interpersonal styles of the therapist, than with his analytical expertise. Such is his conclusion. Apparently social skills are necessary for the professional worker, but intellectual skills for the problems to be unravelled are of little importance, and are largely irrelevant.


Author(s):  
Татьяна Черкашина ◽  
Tatiana Cherkashina ◽  
Н. Новикова ◽  
N. Novikova ◽  
О. Трубина ◽  
...  

The article considers the conceptualization of the world from the point of view of its methodological paradigm assessment in the context of the globalizing world. A retrospective analysis of the relationship between language and human speech activity is given. The authors explain the role of language as a socio-cultural phenomenon in the formation of worldview systems that develop in the consciousness with the help of minimal units of human experience in their ideal meaningful representation in special concepts, which allows the individual to think within the boundaries of a certain linguistic picture of the world. Analyzes the problems of the functioning of communicative norms with regard to the hierarchy of the spiritual representations of the world. The article attempts to consider the impact of the “blurring” of the information boundaries of the globalizing world on the cognitive abilities of the individual in the nomination, qualification of the subject, phenomenon, process.


2016 ◽  
Vol 4 (4) ◽  
pp. 367-384 ◽  
Author(s):  
Thomas Birkner ◽  
Daniel Nölleke

Using the concept of mediatization, in this article, we analyze the relationship between sport and media from a sport-centered perspective. Examining the autobiographies of 14 German and English soccer players, we investigate how athletes use media outlets, what they perceive as the media’s influence and its logic, and—crucially—how this usage and these perceptions affect their own media-related behavior. Our findings demonstrate the important role of the media for the sports systems from the athlete’s point of view and demonstrate the research potential of mediatization as a fruitful concept in studies on sport communication. On the one hand, the sport stars reflect in their autobiographies that their status and income depend on media coverage; and on the other hand, they complain about the omnipresence of the media, especially offside the pitch and feel unfairly treated by the tabloid press, both in England and in Germany.


Popular Music ◽  
2006 ◽  
Vol 25 (2) ◽  
pp. 221-234 ◽  
Author(s):  
MATT BRENNAN

This article explores the relationship between musicians and the music press from the musicians' point of view, based on a collection of recent interviews with musicians working in the pop and jazz fields. It will expose some of the concrete effects of the music press using examples from the everyday experiences of musicians, which include the influence of the press in record retail, genre labelling, and creating industry buzz. But while musicians may have a pragmatic understanding of the role of music criticism, their perspectives are emotionally heated in direct proportion to the influence the press holds over their own livelihoods. The interests of the working music critic often conflict with the interests of the working musician, and this article will conclude with a discussion of how the practical conflict of interests between musicians and critics is reflected in ideological differences between the two groups.


2013 ◽  
Vol 2 (1) ◽  
Author(s):  
Francisco Javier Fuentes Farias

ABSTRACTIf we don't explain the role of language in the construction of places to live, their study will be incomplete; therefore the built space poses the challenge of defining a method of analysis that takes into account the emergence of cognitive processes in human being, of which perception and categorization of objects in space seems to be the most difficult to explain. And here is where the focus on language, from the point of view of the studies of complexity, admits to interpret and explain the evolution of the human capacity of build. In this sense, it is necessary to review the problem of in witch sense it can be said that language is innate or learned, and if the mind is a blank paper at birth, or has a genetic basis and how would be like. We observed the acquisition of language and cognition, and the construction of places to live, as the product of a cultural-genetic legacy. It is necessary to offer a point of view about the relationship between culture-nature, taking built places as a superior order and self-organizing subsystem: the built spaceRESUMENMientras no se exponga el papel del lenguaje en la construcción de lugares para vivir, su estudio estará incompleto; por ello, el espacio construido plantea el reto de definir un método de análisis que tome en cuenta el surgimiento de procesos cognitivos en la especie humana, de los cuales la percepción y categorización de los objetos en el espacio parece ser el más difícil de explicar. Y es aquí donde el enfoque en el lenguaje, desde el punto de vista de los estudios de la complejidad, permite interpretar y explicar la evolución de la capacidad constructiva del ser humano. En tal sentido, es necesario revisar el problema de en qué medida puede afirmarse que el lenguaje es innato o aprendido, y si la mente es un papel en blanco al nacer, o tiene una base genética y cómo sería ello. Se examina la adquisición del lenguaje y la cognición, y la construcción de lugares para vivir, como producto de una herencia genético-cultual. Se ofrece un punto de vista necesario acerca de la relación cultura-naturaleza, considerando los lugares construidos como subsistemas de un orden superior y auto-organizado: el espacio construido.


Author(s):  
V. Litiaga

The article analyzes basic scientific approaches to the interpretation of the terms of «linguoculturology», «linguistic conceptology» and «linguistic concept». We consider the relationship of language and culture, and the role of the term «concept» in this regard. In the article we structured the term «concept» from a linguocultural point of view. These theoretical considerations are the basis for the study of ways and mean of forming a conceptual image of Kyiv Rus in the French medieval linguistic cultural picture of the world. The aim of this article is to examine the influence of the country’s image on shaping the bilateral relations between Ukraine and France in a linguocultural conceptual aspect. The article reveals the main semantic and linguoconceptual aspects of medieval French culture. It shows the links between historical and actual aspects of the conceptual sphere in the formation of public opinion in contemporary international relations. Despite the increasing interest of the scholars in the influence that the image of country may have on bilateral relations, this topic has been under‐researched. This article presents the author’s insights based on theoretical and empirical studies that could shed some new light on this important topic. By looking at the «linguocultural» aspect of the relationship between Kyiv Rus and France in the Medieval times the article gives a basic analysis of the process of country image formation since the tenth century and its impact on present times. The article also provides a basis for further linguistic research of this topic.


2020 ◽  
Vol 8 (12) ◽  
Author(s):  
Maria Navarro

Society has changed dramatically in recent decades not only from the demographic, social and economic point of view, but also from the educational aspect. The current population has higher levels of education than in previous times and can access information in a relatively easy way. In addition, the relationship between the healthcare professional and the patient has evolved from the paternalistic medicine to a more informed and participatory patient-provider relationship. Patient participation and empowerment in the health decision-making process means that the patient has the opportunity to share his/her opinion, knowledge, experience and expectations with other patients, as well as with the health professionals in order to make informed decisions. With this evolution of the role of the patient in the current society, patients have asked for multidisciplinary and coordinated work among professionals to respond to their needs for diagnosis, control and treatment. Patient's participation and empowerment can be conducted both, in the management of the disease, as well as helping to improve different aspects of health services. Participation and empowerment also mean representing other patients. In all cases, patients’ education and training, using clear and plain language, and patients’ confidence play a pivotal role. The aim of this review is to present a summary of the scope of the situation regarding patients’ empowerment and education.


2020 ◽  
Vol 7 (2) ◽  
pp. 38-53
Author(s):  
N.V. Mikhalkin

In its content, this article is focused on solving a number of problems. First, it represents the author's desire to clarify, from the point of view of a philosophical approach to the process of practice-oriented education at the university, the relationship of its components such as information, language and thinking; Secondly, it examines the methodology of the organization of practice-oriented education of students at the university, its content and structure; Thirdly, it is focused on identifying the factorial role of language and thinking in shaping students' skills and skills that enable them to confidently engage in practical activities. Through a consistent identification of the nature and essence of the declared phenomena, the author reveals the basic content of the mutual conditioning of all these processes, taking into account the newly emerging requirements for the education and education of students to practice.


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