Inhibitory control mediates a negative relationship between body mass index and intelligence: A neurocognitive investigation

The aim of this study was to assess the genotoxic and cytotoxic effects that occur in miners working underground in rare metal ore mines at ionizing radiation levels within the maximum permissible concentration (MPC) standards using the buccal micronucleus cytome (BMCyt) assay. At the same time, we attempted to identify possible relationships between cytogenetic abnormalities in the buccal epithelium and such physiological indicators as cardiodynamics and the body mass index. The study involved a total of 269 individuals, 236 miners working underground in production related to the mining and enrichment of loparite ores and 33 non-exposed individuals (Russia, Murmansk region). Buccal micronucleus cytome assay and heart rate variability parameters were used. Micronucleus frequency was revealed to be a higher in the exposed group (8.3 ± 1.08‰) than in the non-exposed group (3.3 ± 0.49‰). The repair index showed a statistically significant increase in the non-exposed group (14.9 ± 2.90) compared with the exposed group (6.1 ± 0.74). The frequency of nuclear protrusions correlates significantly with the body mass index in the young miners (≤30 years (r = 0.45)). There is a negative relationship between the micronucleus frequency and the level of organism adaptation (r = −0.24), the vegetative regulation rate (r = −0.20) and the psycho-emotional state (r = −0.30) for miners older than 30 years. The results testify to the possible induction of clastogenic effects and a decrease in the level of reparation in the buccal epithelium cells due to the exposure of a various of production factors in the extraction of loparite ore.

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Body Mass Index Moderates the Association between Sleep Quality and Vigilance on a Test of Inhibitory Control

The Clinical Neuropsychologist ◽

10.1080/13854046.2015.1096961 ◽

2015 ◽

Vol 29 (6) ◽

pp. 863-875 ◽

Cited By ~ 1

Author(s):

Rachel Galioto ◽

William V. Lechner ◽

Jonah Meister ◽

Micah Wright ◽

John Gunstad ◽

...

Keyword(s):

Body Mass Index ◽

Sleep Quality ◽

Body Mass ◽

Inhibitory Control

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Demographic, lifestyle, and reproductive determinants of serum anti-Müllerian hormone levels in adult women of reproductive age in Ilorin, North-Central Nigeria

Middle East Fertility Society Journal ◽

10.1186/s43043-021-00069-0 ◽

2021 ◽

Vol 26 (1) ◽

Author(s):

Oyinkansola Islamiyat Lawal ◽

Jameelu-deen Omokunmi Yusuff

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Cycle Length ◽

Univariate Analysis ◽

Multivariable Analysis ◽

Negative Relationship ◽

Reproductive Age ◽

Enzyme Linked Immunosorbent Assay ◽

Adult Women ◽

Women Of Reproductive Age

Abstract Background Anti-Müllerian hormone is a dimeric glycoprotein produced by the granulosa cells of preantral and small antral follicles of the ovaries. It is a reliable biomarker of ovarian reserve, ageing, and response in the management of women with infertility. However, there are few studies on the determinants of serum anti-Müllerian hormone in Nigerian women. This study aimed to investigate determinants of serum anti-Müllerian hormone among adult women of reproductive age. The study was a hospital-based cross-sectional study involving 161 women of reproductive age attending the gynaecology clinic and immunisation clinic of a Nigerian tertiary hospital. Baseline characteristics were collected using a semi-structured questionnaire. Serum anti-Müllerian hormone was quantified using enzyme-linked immunosorbent assay. Results In univariate analysis, age (B = − 0.035, P = 0.000), parity (B = − 0.080, P = 0.001), and infertility duration (B = − 0.050, P = 0.011) had a negative relationship with serum anti-Müllerian hormone, while ethnicity (B = 0.180, P = 0.040), body mass index (B = 0.015, P = 0.010), and cycle length (B = 0.042, P = 0.000) had a positive relationship with serum anti-Müllerian hormone. In multivariable analysis, all relationships except infertility duration persisted. Conclusion We found that age, ethnicity, parity, infertility duration, body mass index, and cycle length were associated with serum anti-Müllerian hormone. A large prospective population-based study is required to better understand factors that are associated with serum anti-Müllerian hormone in an ethnically diverse country like Nigeria.

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Associations between Park and Playground Availability and Proximity and Children’s Physical Activity and Body Mass Index: The BEACH Study

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph19010250 ◽

2021 ◽

Vol 19 (1) ◽

pp. 250

Author(s):

Javier Molina-García ◽

Cristina Menescardi ◽

Isaac Estevan ◽

Ana Queralt

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Body Mass ◽

Weight Status ◽

Negative Relationship ◽

Cross Sectional Study ◽

Geographical Information ◽

Active Commuting ◽

Cross Sectional ◽

Parent Questionnaire

A cross-sectional study was designed to evaluate the relationship between the availability and proximity to parks and playgrounds and physical activity (PA). Moreover, the accessibility to parks and playgrounds and its association with active commuting to/from school (ACS) and body mass index (BMI) were analyzed. The sample was composed of children aged 6–12 years old from the BEACH (Built Environment and Active CHildren) study in Valencia, Spain. The availability and proximity to parks and playgrounds were calculated at different buffer sizes (250, 500, 1000 and 1250 m) using geographical information system data. PA out of school was assessed using accelerometers. Sociodemographics and ACS were measured with a parent questionnaire. Objectively measured weight and height were used to calculate BMI. Mixed linear regression analyses were conducted for each exposure variable, adjusting for sociodemographics, neighborhood walkability level, and participant clustering. The number of parks and playgrounds were positively associated with moderate to vigorous PA (MVPA) and total PA (TPA); including light PA and MVPA, during weekdays, in different buffer sizes. A negative relationship between distance to the nearest playground and TPA during weekdays was found. In addition, the number of playgrounds was positively related to ACS in different buffer sizes, whereas park land area was negatively related to the BMI percentile. This study highlights the importance of assessing the availability and proximity to parks and playgrounds in children’s neighborhoods when PA behavior and weight status are analyzed. Study findings may help policymakers when targeting interventions to promote health-enhancing behaviors in children.

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HUBUNGAN ASUPAN ZAT GIZI MIKRO, DURASI TIDUR, INDEKS MASSA TUBUH DAN STATUS IMUN PEGAWAI BALITBANG HUKUM DAN HAM

Journal of Nutrition College ◽

10.14710/jnc.v10i4.31620 ◽

2021 ◽

Vol 10 (4) ◽

pp. 328-334

Author(s):

Anggrita Salsabila Ramadhia ◽

Harna Harna ◽

Mertien Sa'pang ◽

Nadiyah Nadiyah

Keyword(s):

Body Mass Index ◽

Sleep Duration ◽

Body Mass ◽

Immune Status ◽

Negative Relationship ◽

Sampling Technique ◽

P Value ◽

Cross Sectional ◽

Micronutrient Intake ◽

The Relationship

Background: Adequate micronutrients intake is essential to ensure the immune function. Certain populations may have insufficient intake of micronutrients, and in situations that increase the demand for example infections, stress, and pollution that decrease the body's stores of micronutrients, putting them at risk of deficiency and may impair immunity. Several researchs related to micronutrient intake, nutritional status, sleep duration are still contradictory results in showing the relationship with immunity.Objectives: To determine the relationship between micronutrient intake, sleep duration, body mass index and the immune status of Balitbang Hukum dan HAM employees.Methods: This type of research is an observational study with a cross sectional approach. The sampling technique used was simple random sampling technique. The samples taken were 47 people.Results: Median intake of micronutrient vitamin A 1024.5 mcg, vitamin C 208.3 mg, vitamin D 1.4 mcg, vitamin E 3.5 mg, iron 5.1 mg, zinc 4.2 mg. Meanwhile, the median sleep duration was 6 hours and the median body mass index was 22.2 kg / m2. The intake of micronutrients with immune status has a p value> 0.05. Sleep duration with immune status has a p value <0.05 with a negative relationship direction. Body mass index with immune status has a p value> 0.05.Conclusion: There is no relationship between micronutrient intake and body mass index with immune status, meanwhile there is a relationship between sleep duration and immune status of Balitbang Hukum dan HAM employees.Keywords : Micronutrient intake; Sleep duration; Body mass index; Immune status

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Motivational Climate towards the Practice of Physical Activity, Self-Concept, and Healthy Factors in the School Environment

Sustainability ◽

10.3390/su11040999 ◽

2019 ◽

Vol 11 (4) ◽

pp. 999 ◽

Cited By ~ 2

Author(s):

Manuel Castro-Sánchez ◽

Félix Zurita-Ortega ◽

Eduardo García-Marmol ◽

Ramón Chacón-Cuberos

Keyword(s):

Body Mass Index ◽

Mediterranean Diet ◽

Body Mass ◽

School Children ◽

Structural Equation ◽

Negative Relationship ◽

Motivational Climate ◽

Self Concept ◽

Positive Effects ◽

Task Oriented

The objective of the present study was to define and contrast an explanatory model relating the motivational climate, body mass index, and adherence to a Mediterranean diet with the self-concept of school children. A further objective was to analyze the existing relationships between the variables included in the developed model according to sex, using a multi-group structural equation analysis. In the study, a total of 734 school children, of both sexes, reported their perceived motivational climate towards sport, body mass index, adherence to a Mediterranean diet, and self-concept. These children were aged between 10 and 12 years old and attended public school in the province of Granada (Spain). The multi-group structural equation model developed demonstrated an excellent fit to the empirical data (χ2 = 228.179; DF = 40; p < 0.001; CFI = 0.965; NFI = 0.958; IFI = 0.968; RMSEA = 0.048). The findings identified a direct negative relationship between the ego climate and the task climate. Furthermore, an inverse relationship was found between the task climate and body mass index, and a direct relationship was found between the ego climate and body mass index. Meanwhile, Mediterranean diet adherence was directly related to the task climate and negatively related to the ego climate. The main conclusions of the present study highlight the positive effects of a task-oriented motivational climate and adherence to a Mediterranean diet, with regards to body mass index. Furthermore, a task-oriented motivational climate and a lower body mass index are related to a more positive self-concept.

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Accuracy of Pharmacokinetic Models for Predicting Plasma Fentanyl Concentrations in Lean and Obese Surgical Patients

Anesthesiology ◽

10.1097/00000542-200409000-00008 ◽

2004 ◽

Vol 101 (3) ◽

pp. 603-613 ◽

Cited By ~ 79

Author(s):

Kinichi Shibutani ◽

Mario A. Inchiosa ◽

Keisuke Sawada ◽

Mosses Bairamian

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Body Mass ◽

Predictive Accuracy ◽

Elective Surgery ◽

Negative Relationship ◽

Obese Patients ◽

Pharmacokinetic Models ◽

The Mean ◽

Total Body

Background The currently available pharmacokinetic models for fentanyl were derived from normal weight patients and were not scaled to body weight. Their application to obese patients may cause overprediction of the plasma concentration of fentanyl. This study examined the influence of body weight on the predictive accuracy of two models (Anesthesiology 1990; 73:1091-102 and J Pharmacol Exp Ther 1987; 240:159-66). Further, we attempted to derive suggested dosing mass weights for fentanyl that improved predicted accuracy. Method Seventy patients undergoing major elective surgery with total body weight (TBW) <85 kg and body mass index <30 (Group L) and 39 patients with TBW >/=85 kg and body mass index >30 (Group O) were studied. In Group L and Group O, the mean TBW was 69 kg, and 125 kg, respectively and the mean body mass index in Group L and Group O was 24 and 44, respectively. Fentanyl infusion was used during surgery and postoperatively for analgesia. Plasma fentanyl concentrations were measured and predicted concentrations were obtained by computer simulation; 465 pairs of measured and predicted values were obtained. Results The influence of TBW on the performance errors of the original two models was examined with nonlinear regression analysis. Shafer error versus TBW showed a highly significant negative relationship (R squared = 0.689, P < 0.001); i.e., the Shafer model systematically overestimated fentanyl concentration as weight increased. The Scott and Stanski model showed greater variation (R squared = 0.303). We used the exponential equation for Shafer performance error versus TBW to derive suggested dosing weights ("pharmacokinetic mass") for obese patients. The pharmacokinetic mass versus TBW curve was essentially linear below 100 kg (with slope of 0.65) and approached a plateau above 140 kg. For patients weighing 140 to 200 kg, dosing weights of 100-108 kg are projected. Total body clearance (ml/min) showed a strong linear correlation with pharmacokinetic mass (r = 0.793; P < 0.001), whereas the relationship with TBW was nonlinear. Conclusion Actual body weight overestimates fentanyl dose requirements in obese patients. Dosing weight (pharmacokinetic mass) derived from the nonlinear relationship between prediction error and TBW proved to have a linear relationship with clearance.

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Age, body mass index, race and other determinants of steroid hormone variability: the HERITAGE Family Study

Acta Endocrinologica ◽

10.1530/eje.0.1450001 ◽

2001 ◽

pp. 1-9 ◽

Cited By ~ 95

Author(s):

O Ukkola ◽

J Gagnon ◽

T Rankinen ◽

PA Thompson ◽

Y Hong ◽

...

Keyword(s):

Body Mass Index ◽

Steroid Hormones ◽

Body Mass ◽

Family Study ◽

Steroid Hormone ◽

Negative Relationship ◽

Sex Hormone Binding Globulin ◽

Regression Methods ◽

Major Predictor ◽

17 Hydroxyprogesterone

OBJECTIVE AND METHODS: To investigate from the HERITAGE Family Study database, 13 steroid hormones (androstane-3alpha, 17beta-diol glucuronide, androsterone glucuronide, cortisol, dehydroepiandrosterone (DHEA), DHEA ester (DHEAE), DHEA sulfate (DHEAS), dihydrotestosterone (DHT), estradiol, 17-hydroxyprogesterone, progesterone, pregnenolone ester, sex hormone binding globulin (SHBG) and testosterone in each sex for their relationships with age, body mass index (BMI), race and key lifestyle variables. Sample sizes varied from 676 to 750 per hormone. Incremental regression methods were used to examine the contributions of the variables to steroid hormone variability. RESULTS: Age was a major predictor for most steroid hormones. The greatest contribution of age was a negative relationship with DHEAS (R(2)=0.39). BMI was also associated with the variability of several steroid hormones, being the most important predictor of SHBG (R(2)=0.20) and of testosterone (R(2)=0.12) concentrations. When age and BMI were included, race still contributed significantly to the variations in cortisol (R(2)=0.02 for men and 0.04 for women), DHT (R(2)=0.02 for men and 0.03 for women), and progesterone (R(2)=0.03 for women). Nevertheless, race appeared to be less important than age and BMI. In addition, lifestyle indicators (food and nutrient intakes, smoking and physical activity) influenced steroid hormone variability. Their contributions, however, were minor in most cases once age, BMI and race had been taken into account. CONCLUSIONS: We conclude that age was the most important factor, followed by BMI, race and lifestyle factors in explaining steroid hormone variability.

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PREDICTION OF PHYSICAL VARIABLE TO SQUAT LONG JUMP ACHIEVEMENT (A MULTIVARIATE CORRELATIONAL STUDY ON TRAINED STUDENTS OF A STATE SENIOR HIGH SCHOOL IN PEKALONGAN REGENCY)

International Journal of Education ◽

10.17509/ije.v10i2.8861 ◽

2018 ◽

Vol 10 (2) ◽

Author(s):

Abdurachman Abdurrachman ◽

Sugiyanto Sugiyanto ◽

Muchsin Doewes

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Negative Relationship ◽

Total Sample ◽

Limb Length ◽

Running Speed ◽

Long Jump ◽

Physical Abilities ◽

Correlational Method ◽

Linearity Test

Achievement of squat long jump needs to be supported with several components that are divided into anthropometric elements and physical abilities. This study aims to determine the relationship and the extent to which squat long jump achievement can predict limb length, body mass index, body flexibility, and running speed. The subjects of this research were trained students of state senior high schools in Pekalongan Regency, with a total sample of 60 students. The independent variables in this research included limb length, body mass index, body flexibility, and running speed, whereas the dependent variables consisted of long jump and squat style achievement. The data were obtained through the test and measurement of each variable. This study used multivariate correlational method. Data were analyzed with normality test, linearity test, simple and multiple regression analysis, and hypotheses were tested with t-test and F-test. The results showed that limb length, body mass index, and flexibility had a positive relationship, whereas body mass index and running speed had a negative relationship with the squat long jump achievement. The prediction value of limb length was 0.027, body mass index -0.049, body flexibility 0.026, and running speed -0.234. The conclusion of this study is that there was a significant relationship among the variables, and limb length, body mass index, body flexibility and running speed can be predicted based on squat long jump achievement.

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Interrelationships among body mass, thyrotropin, thyroid hormones, and thyroid-hormone binding proteins in healthy 70-year-old men.

Clinical Chemistry ◽

10.1093/clinchem/30.5.681 ◽

1984 ◽

Vol 30 (5) ◽

pp. 681-686 ◽

Cited By ~ 6

Author(s):

S Edén ◽

R Jagenburg ◽

G Lindstedt ◽

P A Lundberg ◽

D Mellström

Keyword(s):

Body Mass Index ◽

Thyroid Hormone ◽

Body Mass ◽

Binding Proteins ◽

Dominant Role ◽

Negative Relationship ◽

Feedback Regulation ◽

Hormone Binding ◽

Free T4 ◽

Old Men

Abstract In a previous study of a representative population of 460 men of age 70, we found that the free thyroxin (free T4) concentration was negatively correlated to body mass. In the present study we analyzed other indicators of thyroid function in relation to body mass and body mass index in 181 individuals without any disease or medication influencing thyroidal homeostasis or body mass. There was a significant negative relationship between body mass and body mass index and free T4, total T4, and 3,3',5'-triiodothyronine (rT3). Thus, individuals with high body mass normally had lower circulating concentrations of these hormones than lean individuals, whereas there was no such relationship for thyrotropin or 3,5,3'-triiodothyronine (T3). The thyroid-hormone binding proteins (thyroxin-binding globulin, prealbumin, and albumin) did not correlate with body mass or body mass index. As expected, thyroxin-binding globulin correlated with T4, T3, and rT3, but not with free T4 or thyrotropin. Concentrations of serum albumin correlated with T3 and rT3 concentrations but not with free T4, T4, or thyrotropin concentrations. Thyrotropin concentrations correlated negatively with free T4, T4, and rT3, but not with T3, indicating that circulating T4 plays the dominant role in feedback regulation of thyrotropin in healthy individuals.

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