scholarly journals The knowledge regarding Breast Cancer, its risk factors, and screening practices among women from Islamabad, Pakistan

2021 ◽  
Vol 25 (1) ◽  
pp. 83-86
Author(s):  
Sadia Yasir Khan ◽  
Sadaf Konain Ansari ◽  
Mohsin Khalid Qureshi ◽  
Tamkeen Nishat Jaffrey ◽  
Farah Rashid
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Strong Association ◽  
Public Health Problem ◽  
Screening Tests ◽  
P Value ◽  
Asian Countries ◽  
Screening Practices ◽  
Western Countries ◽  
Medical Facilities

Introduction: Breast Cancer is the rising Public health problem of the world. Pakistan is bearing a high disease burden not only in Asian countries but in the whole world. Pakistan ranks highest in Breast cancer and accounts for almost 34.6%of female cancers. The incidence of the disease in Asian countries is quite different from that in Western countries regarding age i.e. (40-50 years.) while (60-70 years) in Western countries. This study was based on assessing the knowledge regarding breast cancer, risk factors, and screening practices to determine the barriers in the path of the community to seek medical care.Materials and Methods: A cross-sectional study was done between October to December 2019 on 310 females participants of ages from 25 to 70 years, residents of Islamabad, the capital of Pakistan, and knowledge was assessed by applying a self-responding questionnaire.Results: Using SPSS version 23 and chi-square tests, the results showed that 87.7% of participants knew about the prevalence of Breast Cancer. Whereas, 90.3% of the females with the disease are not aware of their illness and show a strong association (p-value is less than 0.05) between knowledge regarding breast cancer and screening tests. Conclusion: The study concluded that 90% of socio-cultural barriers are in the path of access to medical facilities and 90% of participants believed that the non-availability of female doctors in health facilities is a big barrier to access to health. Access to medical facilities should be made easy by promoting health education and removing the fear of results, making small health facility units.  

Examination of incidence, mortality and disability-adjusted life years and risk factors of breast cancer in 49 Asian countries, 1990–2019: estimates from Global Burden of Disease Study 2019

2021 ◽  
Author(s):  
Rajesh Sharma
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Mortality Rate ◽  
Burden Of Disease ◽  
Global Burden ◽  
Disability Adjusted Life Years ◽  
Asian Countries ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Standardized Mortality Rate

Abstract Background This study presents an up-to-date, comprehensive and comparative examination of breast cancer’s temporal patterns in females in Asia in last three decades. Methods The estimates of incidence, mortality, disability-adjusted-life-years and risk factors of breast cancer in females in 49 Asian countries were retrieved from Global Burden of Disease 2019 study. Results In Asia, female breast cancer incidence grew from 245 045[226 259–265 260] in 1990 to 914 878[815 789–1025 502] in 2019 with age-standardized incidence rate rising from 21.2/100 000[19.6–22.9] to 35.9/100 000[32.0–40.2] between 1990 and 2019. The death counts more than doubled from 136 665[126 094–148 380] to 337 822[301 454–375 251]. The age-standardized mortality rate rose marginally between 1990 and 2019 (1990: 12.1[11.0–13.1]; 2019: 13.4[12.0–14.9]). In 2019, age-standardized incidence rate varied from 17.2/100 000[13.95–21.4] in Mongolia to 122.5[92.1–160.7] in Lebanon and the age-standardized mortality rate varied 4-fold from 8.0/100 000 [7.2–8.8] in South Korea to 51.9[39.0–69.8] in Pakistan. High body mass index (5.6%), high fasting plasma glucose (5.6%) and secondhand smoke (3.5%) were the main contributory risk factors to all-age disability-adjusted-life-years due to breast cancer in Asia. Conclusion With growing incidence, escalating dietary and behavioural risk factors and lower survival rates due to late-disease presentation in low- and medium-income countries of Asia, breast cancer has become a significant public health threat. Its rising burden calls for increasing breast cancer awareness, preventive measures, early-stage detection and cost-effective therapeutics in Asia.

scholarly journals Substance Use: Prevalence, Pattern and Risk Factors among Undergraduate Students in a Tertiary Institution in Southwest Nigeria

2021 ◽  
Vol 33 (2) ◽  
pp. 83-99
Author(s):  
K.A. Durowade ◽  
O.E. Elegbede ◽  
G.B. Pius-Imue ◽  
A. Omeiza ◽  
M. Bello ◽  
...  
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Secondary Education ◽  
Undergraduate Students ◽  
Statistical Significance ◽  
Public Health Problem ◽  
Peer Pressure ◽  
Civil Servant ◽  
P Value ◽  
Global Public Health

Background: Substance use is a global public health problem with increasing burden among university students. This study assessed the prevalence, pattern and risk factors of substance use among undergraduate students of Afe Babalola University, Ado-Ekiti, Nigeria.Methods: This was a cross-sectional study of undergraduate students of Afe Babalola University, Ado-Ekiti. A multi-stage sampling technique was used to select respondents. Data collection tool was a structured self-administered questionnaire. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 23. Statistical significance was set at p value <0.05Results: The respondents’ mean age was 19.5 ± 2.0 years and all 416 (100.0%) were aware of substance abuse. The prevalence of substance use was 299 (71.9%). Alcohol 133 (32.0%) and over-the-counter drugs (29.9%) were the two most commonly used substance. Being male (p=0.017) and in 400 level (p=0.047) were associated with substance use while curiosity 112 (37.5%), peer pressure 95 (31.8%) and school stress 85 (28.4%) were reasons given. Predictors of substance use were being a female (aOR: 2.54; 95% CI=1.89-3.66; p=0.011), civil servant mother (aOR: 5.75; 95% CI=1.90-17.4; p=0.002) and mother with secondary education (aOR: 5.27; 95% CI= 2.20- 12.65; p<0.001).Conclusion: There was high prevalence of substance use with curiosity, peer pressure and school stress being influencers of substance use among the study population. Predictors of substance use were being a female, civil servant mother and mother with secondary education. The University authority should institute measures to prevent access to alcohol and other substances by the students.

scholarly journals Seroprevalence Study of Anti-HEV IgG among Different Adult Populations in Corsica, France, 2019

2019 ◽  
Vol 7 (10) ◽  
pp. 460 ◽  
Author(s):  
Capai ◽  
Masse ◽  
Gallian ◽  
Souty ◽  
Isnard ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Practice ◽  
Blood Donors ◽  
Adult Population ◽  
Strong Association ◽  
Hepatitis E ◽  
Cross Sectional Study ◽  
Antibody Detection ◽  
P Value ◽  
Cross Sectional

Hepatitis E virus (HEV) is a major cause of acute hepatitis worldwide. In France, hyperendemic areas including Corsica have an anti-HEV Immunoglobulin G (IgG) prevalence higher than 50%. The aim of this study was to determine the seroprevalence of anti-HEV IgG in three adult populations in Corsica and the risk factors associated with antibody detection. Between 2017 and 2019, a total of 930 individuals, including 467 blood donors, 393 students or university staff members and 70 patients from general practice, were tested for the presence of anti-HEV IgG using the Wantai HEV IgG enzyme immunoassay kit and filled a questionnaire. The association between seropositivity and potential risk factors was tested with univariate and multivariate analyses. Out of the 930 samples, 52.3% (486/930) were seropositive—54.4% (254/467) among blood donors, 47.6% (187/393) among university students and 64.3% (45/70) among patients of general practice. Three main risk factors were identified: (i) skinning and butchering (Adjusted Odds Ratio aOR = 2.76, 95% confidence interval [95% CI] [1.51–5.37]; p-value < 10−3), (ii) consumption of a local pork live raw sausage (fittonu) (aOR = 1.95 95% CI [1.45–2.64]; p-value = 10−5), and (iii) increasing age (p-value = 0.003). Seropositivity rates between the different populations were homogeneous after age stratification. This cross-sectional study indicates a high anti-HEV IgG seroprevalence in the Corsican adult population, not significantly different between women and men and increasing with age. This serosurvey also showed homogeneity regarding the exposure to HEV among three different types of populations. Finally, we confirmed the endemicity of Corsica with respect to HEV and identified a strong association between consumption of figatellu/fittonu and the practice of skinning and butchering with the detection of anti-HEV IgG.

A PRELIMINARY STUDY OF RISK FACTORS OF BREAST CANCER AND THE USEFULNESS OF BREAST MRI AS AN ADDITION TO MAMMOGRAPHY IN DETECTING BREAST CANCER IN HIGH RISK WOMEN

2016 ◽  
Vol 78 (11-3) ◽  
Author(s):  
Noor Khairiah A. Karim ◽  
Rohayu Hami ◽  
Nur Hashamimi Hashim ◽  
Nizuwan Azman ◽  
Ibrahim Lutfi Shuaib
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
High Risk ◽  
Cancer Detection ◽  
Significant Risk ◽  
Breast Mri ◽  
Breast Cancer Detection ◽  
P Value ◽  
High Risk Women ◽  
History Of

The risk factors of breast cancer among women, such as genetic, family history and lifestyle factors, can be divided into high-, intermediate- and average-risk. Determining these risk factors may actually help in preventing breast cancer occurrence. Besides that, screening of breast cancer which include mammography, can be done in promoting early breast cancer detection. Breast magnetic resonance imaging (MRI) has been recommended as a supplemental screening tool in high risk women. The aim of this study was to identify the significant risk factor of breast cancer among women and also to determine the usefulness of breast MRI as an addition to mammography in detection of breast cancer in high risk women. This retrospective cohort study design was conducted using patients’ data taken from those who underwent mammography for screening or diagnostic purposes in Advanced Medical and Dental Institute, Universiti Sains Malaysia, from 2007 until 2015. Data from 289 subjects were successfully retrieved and analysed based on their risk factors of breast cancer. Meanwhile, data from 120 subjects who had high risks and underwent both mammography and breast MRI were further analysed. There were two significant risk factors of breast cancer seen among the study population: family history of breast cancer (p-value=0.012) and previous history of breast or ovarian cancer (p-value <0.001). Breast MRI demonstrated high sensitivity (90%) while mammography demonstrated high specificity (80%) in detection of breast cancer in all 120 subjects. The number of cases of breast cancer detection using breast MRI [46 (38.3%)] was higher compared to mammography [24 (20.0%)]. However, breast MRI was found to be non-significant as an adjunct tool to mammography in detecting breast cancer in high risk women (p-value=0.189). A comprehensive screening guideline and surveillance of women at high risk is indeed useful and should be implemented to increase cancer detection rate at early stage

scholarly journals Current Status and Future Projections of Breast Cancer in Asia

Breast Care ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. 372-378 ◽  
Author(s):  
Lei Fan ◽  
Paul E. Goss ◽  
Kathrin Strasser-Weippl
Keyword(s):  
Breast Cancer ◽  
Socioeconomic Development ◽  
Control Measures ◽  
Current Status ◽  
Breast Cancers ◽  
Asian Countries ◽  
Middle Income ◽  
Cancer Risk Factors ◽  
Western Countries ◽  
Breast Cancer Risk Factors

Asia is the world's largest continent comprising about 3/5 of the human population. Breast cancer is the most common type of cancer and the second leading cause of cancer-related deaths among women in Asia, accounting for 39% of all breast cancers diagnosed worldwide. The incidence of breast cancer in Asia varies widely across the continent and is still lower than in Western countries, but the proportional contribution of Asia to the global breast cancer rates is increasing rapidly in parallel to the socioeconomic development. However, the mortality-to-incidence ratios are much higher for Asia than for Western countries. Most Asian countries are low- and middle-income countries (LMICs) where breast cancer presents at a younger age and a later stage, and where patients are more likely to die from the disease than those in Western countries. Moreover, diagnostic workup, treatment and palliative services are inadequate in most Asian LMICs. In this review, we present an overview of the breast cancer risk factors and epidemiology, control measures, and cancer care among Asian countries.

scholarly journals KEJADIAN KANKER PAYUDARA (STUDI RETROSPEKTIF) DI LAMPUNG, INDONESIA

2019 ◽  
Vol 13 (2) ◽  
pp. 172-183
Author(s):  
Nurhayati Nurhayati ◽  
Zaenal Arifin ◽  
Hardono Hardono
Keyword(s):  
Breast Cancer ◽  
Risk Factors ◽  
Contraceptive Use ◽  
Health Workers ◽  
Case Control ◽  
Observational Research ◽  
P Value ◽  
Childbearing Age ◽  
Chi Square ◽  
The World

ABSTRACT: THE INCIDENCE OF BREAST CANCER IN LAMPUNG INDONESIA: A RETROSPECTIVE COHORT ANALYSISBackground: Cancer is the second leading cause of death in the world, the highest type of cancer in women in the world is breast cancer with an incidence of 38 per 100,000 women. In Indonesia by 2012 the incidence of breast cancer in Indonesia is 40 per 100,000 women. The incidence of breast cancer in the city of Bandar Lampung is 80 per 100,000 population.Purpose : Knowing risk factors incidence of breast cancer in the Foundation of Cancer Indonesia in Bandar Lampung 2017.Methods: The quantitative and observational research with case control design. The population of this study were all patients who had done counseling and examination by Cancer counseling institute of Indonesia during the period of research as much as 691 respondent, with the required number of samples 126 rspondent. Bivariate analysis was done with chi square (X2), while multivariate analysis using multiple linear logistic regression .Results: The risk factors such as menarche (p-value = 0.002), parity (p-value = 0,018), breastfeeding (p-value = 0,000) and duration of contraceptive use (p-value = 0, 02), while factors unrelated to breast cancer were family history (p-value = 0.112) and age (value = 0.357).Conclusion: The most influential variable on the incidence of breast cancer is the variable duration of contraceptive use. For health workers need to do counseling about breast cancer risk factors. Women of childbearing age should use non-hormonal family planning, when using a type of hormonal contraception need to be consult with local health workers and avoid births that are too frequent.Keywords: Factor Analysis, Breast Cancer, Breast Cancer History, Age of Menarche, Age, Parity, Breastfeeding Status, Hormonal Contraception.Pendahuluan : Kanker adalah penyebab kematian nomor dua di dunia, jenis kanker tertinggi pada wanita di dunia adalah kanker payudara dengan insidensi 38 per 100.000 wanita. Di Indonesia pada tahun 2012, insiden kanker payudara di Indonesia adalah 40 per 100.000 wanita. Angka kejadian kanker payudara di kota Bandar Lampung adalah 80 per 100.000 penduduk.Tujuan: Diketahui faktor-faktor risiko kejadian kanker payudara di Yayasan Kanker Indonesia di Bandar Lampung 2017.Metode: Jenis penelitian yang akan digunakan peneliti adalah kuantitatif. Desain penelitian yang digunakan adalah penelitian observasional dengan desain case control. Populasi penelitian ini adalah semua pasien yang telah melakukan konseling dan pemeriksaan oleh lembaga konseling kanker Indonesia selama periode penelitian sebanyak 691 orang, dengan jumlah sampel yang dibutuhkan 126 orang. Analisis bivariat dilakukan dengan chi square (X2), sedangkan analisis multivariat menggunakan regresi logistik linier berganda.Hasil: faktor risiko kanker payudara seperti menarche (p-value = 0,002), paritas (p-value = 0,018), menyusui (p-value = 0,000) dan durasi penggunaan kontrasepsi (p-value = 0, 02), sedangkan faktor-faktor yang tidak berhubungan dengan kanker payudara adalah riwayat keluarga (p-value = 0,112) dan usia (nilai = 0,357).Simpulan: Variabel yang paling berpengaruh pada kejadian kanker payudara adalah variabel lamanya penggunaan kontrasepsi. Untuk tenaga kesehatan perlu melakukan penyuluhan tentang faktor risiko kanker payudara. Untuk WUS, sebaiknya menggunakan KB non hormonal, jika terpaksa menggunakan jenis kontrasepsi hormonal sebaiknya dikonsultasikan terlebih dahulu dengan petugas kesehatan setempat dan hindari kelahiran yang terlalu rapat.

scholarly journals Prevalence of Psoriasis Vulgaris and Its Associated Risk Factors in Pakistan

2021 ◽  
pp. 390-395
Author(s):  
Syeda Ujala Sohail ◽  
Nasima Iqbal ◽  
Ashok Kumar ◽  
Sarwath Fatimee ◽  
Ayesha Khan ◽  
...  
Keyword(s):  
Risk Factors ◽  
Standard Deviation ◽  
Family History ◽  
Psoriasis Vulgaris ◽  
Age Of Onset ◽  
Strong Association ◽  
Positive Family History ◽  
P Value ◽  
History Of ◽  
Associated Risk Factors

Aim: To find out the prevalence of psoriasis vulgaris and its associated risk factors. Study Design: Descriptive cross-sectional. Place and Duration of Study: Study was conducted at Rawalpindi Leprosy Hospital during January 2019 to December 2019. Methodology: The diagnosed cases of Psoriasis Vulgaris (PsV) were included in the study. All the patients were investigated on the basis of an in depth Performa. The Performa include all the relevant clinical and family history of the patient along with the personal details. Data was analyzed by using Statistical Package for the Social Sciences (SPSS) version 20. All the numerical variables were presented as mean with standard deviation while categorical data as frequency and percentages. The association of risk factors with the Psoriasis was calculated by using the Chi-square test. p-value less than 0.05 was considered as significant. Results: Mean age with standard deviation of patients was 34.7±14. Most of the diagnosed patients were male and below 40 years of age, only 4.2% cases were having positive family history of Psoriasis and found significant correlation. The frequency of onset of symptoms in adolescent was more as compared to childhood i.e. 95.3% and 4.7% respectively. Majority of psoriasis cases (65.3%) were from non-smoker group and having strong association with smoking. The frequency of arthritis among psoriasis patients was 23.7% and majority of the patients, who developed arthritis were those having age <40 year and were suffering from psoriasis since 5-10 years. Conclusion: Current study concluded that Psoriasis vulgar is having higher prevalence rate among male and below 40 years of age group. The results also suggested a strong association of severity of psoriasis with certain risk factors including family history, age of onset of symptoms, smoking and arthritis.

scholarly journals Prevalence and risk factors for micronutrient deficiencies in pregnant women at Cayenne maternity, French Guiana

2019 ◽  
Author(s):  
Amandine Duclau ◽  
Fanny Abad ◽  
Antoine Adenis ◽  
Malika Leneuve-Dorilas ◽  
Mathieu Nacher
Keyword(s):  
Risk Factors ◽  
Pregnant Woman ◽  
Pregnant Women ◽  
French Guiana ◽  
Social Inequalities ◽  
Descriptive Analysis ◽  
Public Health Problem ◽  
Micronutrient Deficiency ◽  
P Value ◽  
Micronutrient Deficiencies

Abstract Background Involved in physical and brain development, immune system functioning and various metabolic processes, micronutrients have profound health effects. The nutritional status of the pregnant woman is a major determinant of fetal health. French Guiana has the highest annual population growth rate. Social inequalities, cultural practices and parasitoses in French Guiana could affect the prevalence of these deficiencies. The main objective was to estimate the prevalence of micronutrient deficiency among pregnant women in French Guiana. The secondary objective was to identify socio-demographic, dietary, obstetric and neonatal risk factors associated with deficiencies.Methods Pregnant woman over 22 weeks of pregnancy hospitalized for delivery at the Obstetrical Emergency Department of the Hospital Center in Cayenne from May 2018 to March 2019. A socio-demographic and food questionnaire was administered. Medical data were collected from the medical records. Blood and urine samples were taken. The descriptive analysis used the Student and Chi2 tests. Prevalence ratios were obtained a Poisson regression.Results A total of 341 women were included. The majority were born in Haiti (39%) and French Guiana (34%). At least one micronutrient deficiency was documented in 81% of women. Women receiving State Medical Aid had a 35% greater risk of deficiency during pregnancy compared to those with both normal and complementary health insurance. (PR=1.35 95% CI (1.12;1.63) p-value=0. 002)Conclusions Micronutrient deficiencies in pregnant women in French Guiana are a real public health problem, a fact that was previously overlooked in a context of rising obesity. A varied and balanced diet remains the most effective solution to prevent these deficiencies. In French Guiana, a region where precariousness and obesity are widespread, nutritional care seems urgent.

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