scholarly journals Substance Use: Prevalence, Pattern and Risk Factors among Undergraduate Students in a Tertiary Institution in Southwest Nigeria

2021 ◽  
Vol 33 (2) ◽  
pp. 83-99
Author(s):  
K.A. Durowade ◽  
O.E. Elegbede ◽  
G.B. Pius-Imue ◽  
A. Omeiza ◽  
M. Bello ◽  
...  
Keyword(s):  
Risk Factors ◽  
Substance Use ◽  
Secondary Education ◽  
Undergraduate Students ◽  
Statistical Significance ◽  
Public Health Problem ◽  
Peer Pressure ◽  
Civil Servant ◽  
P Value ◽  
Global Public Health

Background: Substance use is a global public health problem with increasing burden among university students. This study assessed the prevalence, pattern and risk factors of substance use among undergraduate students of Afe Babalola University, Ado-Ekiti, Nigeria.Methods: This was a cross-sectional study of undergraduate students of Afe Babalola University, Ado-Ekiti. A multi-stage sampling technique was used to select respondents. Data collection tool was a structured self-administered questionnaire. Data analysis was done using Statistical Package for the Social Sciences (SPSS) version 23. Statistical significance was set at p value <0.05Results: The respondents’ mean age was 19.5 ± 2.0 years and all 416 (100.0%) were aware of substance abuse. The prevalence of substance use was 299 (71.9%). Alcohol 133 (32.0%) and over-the-counter drugs (29.9%) were the two most commonly used substance. Being male (p=0.017) and in 400 level (p=0.047) were associated with substance use while curiosity 112 (37.5%), peer pressure 95 (31.8%) and school stress 85 (28.4%) were reasons given. Predictors of substance use were being a female (aOR: 2.54; 95% CI=1.89-3.66; p=0.011), civil servant mother (aOR: 5.75; 95% CI=1.90-17.4; p=0.002) and mother with secondary education (aOR: 5.27; 95% CI= 2.20- 12.65; p<0.001).Conclusion: There was high prevalence of substance use with curiosity, peer pressure and school stress being influencers of substance use among the study population. Predictors of substance use were being a female, civil servant mother and mother with secondary education. The University authority should institute measures to prevent access to alcohol and other substances by the students.

Comparative assessment of overweight/obesity among rural and urban reproductive-age women in Ethiopia: Evidence from a cross-sectional 2016 national survey

2021 ◽  
pp. 026010602098234
Author(s):  
Gizachew Worku Dagnew ◽  
Melash Belachew Asresie
Keyword(s):  
Family Size ◽  
Health Problem ◽  
Rural Women ◽  
Alcohol Intake ◽  
Statistical Significance ◽  
Public Health Problem ◽  
Reproductive Age ◽  
P Value ◽  
Cross Sectional ◽  
Reproductive Age Women

Background: Overweight/obesity has become a global health problem for both developed and developing regions. Nowadays, overweight/obesity among childrearing-age women has become rapidly increasing in both urban and rural areas. Aim: This study aimed to assess the variation of overweight/obesity among urban and rural reproductive-age women in Ethiopia. Methods: For this study, the 2016 Ethiopia Demographic and Health Survey data were used. The survey was a community-based cross-sectional study, which used a two-stage stratified cluster sampling technique to select the participants. A total of 13,451 reproductive-age women were included in the analysis. Both descriptive and analytical analysis was performed. A p-value of less than 0.05 was used as the measure of statistical significance. Results: The prevalence of overweight/obesity among urban reproductive-age women was statistically higher ( p = 21.5%; 95% confidence interval (CI): 18.2–25.1) than the rural women ( p = 3.5%; 95% CI: 2.9%–4.2%). Women who attend secondary or above education, women in the age groups 25–34 and ≥ 35 years, and high wealth index (rich) had higher odds of overweight/obesity in both urban and rural women. Moreover, women who were married, who had a large family size, and who have a history of alcohol intake had higher odds of overweight/obesity among urban women. Conclusions: Overweight/obesity among reproductive-age women is a public health problem in Ethiopia, especially for women who are living in urban settings. Therefore, it is important to establish targeted overweight reduction programs with particular emphasis on urban, older aged, educated, and married women. Additionally, encouraging the limitation of the number of family size and alcohol intake can reduce women’s overweight/obesity.

A bioinformatics approach to investigate serum and hematopoietic cell-specific therapeutic microRNAs targeting the 3' UTRs of all four Dengue virus serotypes

2021 ◽  
Author(s):  
Mirza Sarwar Baig ◽  
Anuja Krishnan
Keyword(s):  
Dengue Virus ◽  
Antigen Processing ◽  
Target Genes ◽  
Public Health Problem ◽  
Hematopoietic Cell ◽  
Viral Gene ◽  
P Value ◽  
Pathway Enrichment Analysis ◽  
Global Public Health ◽  
Denv Serotypes

Abstract Hyperendemic circulation of all four Dengue virus (DENV) serotypes is a severe global public health problem, so any vaccine or therapeutics should be able to target all four of them. Cells of hemopoietic origin are believed to be primary sites of DENV replication. This study aimed to identify potential host miRNAs that target 3' UTR of all 4 DENV serotypes, thereby directly regulating viral gene expression or indirectly modulating the host system at different virus infection steps. We used four prediction algorithms viz. miRanda, RNA22, RNAhybrid, and StarMir for predicting miRNA, targeting 3'UTR of all four DENV serotypes. Statistically, the most significant miRNA targets were screened based on their Log10 P-value (&gt; 0.0001) of GO term and KEGG pathway enrichment analysis. The intersection test of at least three prediction tools identified a total of 30 miRNAs, which could bind to 3'UTR of all four DENV serotypes. Of the 30, eight miRNAs were of hematopoietic cell origin. GO term enrichment and KEGG analysis showed four hemopoietic origin miRNAs target genes of the biological processes mainly involved in the innate immune response, mRNA 3'-end processing, antigen processing, and presentation and nuclear-transcribed mRNA catabolic process.

scholarly journals Medication Error in Anaesthesia – A Review

2016 ◽  
Vol 27 (1) ◽  
pp. 31-35
Author(s):  
Montosh Kumar Mondal ◽  
Beauty Rani Roy ◽  
Shibani Banik ◽  
Debabrata Banik
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Medication Error ◽  
Medication Errors ◽  
Health Problem ◽  
Preventive Measures ◽  
Medical Profession ◽  
Public Health Problem ◽  
Global Public Health ◽  
Global Public Health Problem

Medication error is a major cause of morbidity and mortality in medical profession . There is an increasing recognition that medication errors are causing a substantial global public health problem, as many result in harm to patients and increased costs to health providers.Anaesthesia is now safe and routine, yet anaesthetists are not immune from making medication errors and the consequences of their mistakes may be more serious than those of doctors in other specialties. Steps are being taken to determine the extent of the problem of medication error in anaesthesia. In this review, incidence, types, risk factors and preventive measures of the medication errors are discussed in detail.Journal of Bangladesh Society of Anaesthesiologists 2014; 27(1): 31-35

scholarly journals Knowledge and Belief towards Infertility among Undergraduate Students of Selected Colleges of Pokhara Metropolitan City

2019 ◽  
Vol 9 (2) ◽  
pp. 24-28
Author(s):  
Alisha Dhungana ◽  
Kalpana Jnawali
Keyword(s):  
Undergraduate Students ◽  
Public Health Problem ◽  
Knowledge Score ◽  
Female Students ◽  
World Health ◽  
Global Public Health ◽  
Cross Sectional ◽  
Metropolitan City ◽  
Good Level ◽  
Level Of Knowledge

Introduction: Infertility is the global public health problem with adverse social and economic consequences. World Health Organization states that infertility affects 1 in every 10 couples worldwide. This study was carried out with an objective to find out the level of knowledge and belief regarding infertility among undergraduate students. Methods: This was a cross-sectional and quantitative study, carried out among 420 undergraduate students of 7 selected colleges of Pokhara Metropolitan city from July to September 2019. Study populations were selected through simple random sampling method. Data collection was carried out using self-administered questionnaire. Results: Study revealed that 51.9% students had good level of knowledge with the female students having greater knowledge (57%) than male (48%). The study found that students’ knowledge score related to infertility was significantly associated with gender (p<0.05) and parental advices (p<0.05). Conclusions: More than half of the participants had good level of knowledge. Female students were more knowledgeable than male students. Less than half of the participants had ever attended on sexual and reproductive training programs.

scholarly journals Isolation and structure elucidation of anti-malarial principles from Terminalia mantaly H. Perrier stem bark

2021 ◽  
Vol 15 (1) ◽  
pp. 282-292
Author(s):  
Babatunde Samuel ◽  
Yemi Adekola Adekunle
Keyword(s):  
Statistical Significance ◽  
Solvent System ◽  
Stem Bark ◽  
P Value ◽  
Resonance Spectroscopy ◽  
Global Public Health ◽  
1H And 13C Nmr ◽  
Malaria Therapy ◽  
Student’S T

Emergence of malaria parasite resistance to drugs has raised global public health concerns for a compelling need to develop improved malaria therapy. This study is a bio-guided isolation of triterpenoid antimalarial compounds from Terminalia mantaly. Methanol extract of the plant was subjected to column chromatography, and eluted with a ternary solvent system gradient-wise. Two compounds, 1 and 2, were isolated and characterised by spectroscopic data (IR, 1H and 13C NMR, COSY, HMQC, HMBC) and by comparison with literature. Isolated compounds were investigated for antimalarial property by spectrophotometric determination of inhibition of β-Hematin formation, absorbance taken at 405 nm. Results were analysed using Graghpad Prism® (6.0) and presented as mean IC50±SEM. Statistical significance, determined using Student’s t-test and one-way ANOVA, set at p-value of 0.05. Quantitative β-Hematin formation inhibitory activities gave IC50±SEM values of (compound 1; 4.434±0.47), (compound 2; 5.140±4.2) with (chloroquine; 0.335±0.1 mg/ml). Compound 1 was identified as 2,3,19,23-tetrahydroxyolean-12-en-28-oic acid glucopyranoside (arjunglucoside I), and compound2 as its aglycone, 2,3,19,23-tetrahydroxyolean-12-en-28-oic acid (arjungenin). This study provided credence for folkloric use of Terminalia mantaly to treat malaria, and this observed activity was probably due to these isolated triterpenoids.Keywords: β-Hematin, triterpenoids, nuclear magnetic resonance spectroscopy

scholarly journals PERSONAL HYGIENE AND ANTHELMINTIC CONSUMPTION IN PREVENTION OF ENTEROBIASIS AMONG PRIMARY SCHOOL CHILDREN

2020 ◽  
Vol 8 (3) ◽  
pp. 265
Author(s):  
Ratna Muliawati ◽  
Mushidah Mushidah ◽  
Siti Musyarofah
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Primary School ◽  
School Children ◽  
Public Health Problem ◽  
First Grade ◽  
Primary School Children ◽  
Personal Hygiene ◽  
Global Public Health ◽  
Prevalence Odds Ratio

Background: Pinworm infection remains a global public health problem in Indonesia, with the highest prevalence in primary school–aged children. The government has made helminthiasis control efforts through annual deworming every six months, yet data on the enterobiasis prevalence and its risk factors are still limited. Purpose: This research aimed to determine the role of personal hygiene and anthelmintic or worm medicine consumption in the prevention of enterobiasis among primary school children. Methods: This research employed an analytic observational method with a cross-sectional design. The population used was primary school children in the Public Health Center (PHC) of Kaliwungu area, Kendal District, Central Java Province. The research sample was 150 students from first grade to third grade at 1 Primary Elementary School 1 Kutoharjo. The data sources were obtained from interviews of risk factors and perianal swab examinations. The data were analyzed by a chi-square test and multiple logistic regression. Results: The prevalence of pinworm infection among primary school children remains high (37.33%). The results of the multivariate analysis showed that there are three determinant variables of pinworm infections: not washing hands with soap before eating (p < 0.01; Prevalence Odds Ratio (POR) = 6.47; 95% Confidence Interval [CI] = 2.87 < POR < 14.59); not washing hands with soap after defecation (p = 0.01; POR = 3.36; 95% CI = 1.40 < POR < 8.05); and not consuming anthelmintic drugs within the past six months (p = 0.03; POR = 2.43; 95% CI = 1.08 < POR < 5.50). Conclusion: Hand washing habits and annual deworming are important factors to prevent pinworm infections.

scholarly journals Seroprevalence of human Brucellosis and associated risk factors among high-risk occupations in Mbeya Region of Tanzania

2020 ◽  
Vol 6 (1) ◽  
pp. 1 ◽  
Author(s):  
Frederick D. Sagamiko ◽  
Ruth L. Mfune ◽  
Bernard M. Hang’ombe ◽  
Esron D. Karimuribo ◽  
Alfred M. Mwanza ◽  
...  
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Statistical Significance ◽  
Raw Milk ◽  
Enzyme Linked Immunosorbent Assay ◽  
Human Brucellosis ◽  
P Value ◽  
Cross Sectional ◽  
Occupationally Exposed ◽  
Associated Risk Factors

Background: Brucellosis is a bacterial zoonotic disease of public health and economic importance. A cross-sectional study was conducted in Mbeya region between November 2015 and January 2016 to investigate the seroprevalence of human brucellosis and identify associated risk factors among individuals in risky occupations. Methods: A total of 425 humans from six occupational categories were serially tested for Brucella antibodies using the Rose Bengal Plate Test (RBPT) and competitive Enzyme Linked Immunosorbent Assay (c-ELISA), for screening and confirmation, respectively. A questionnaire survey was also administered to participants to collect epidemiological data. Results: The overall seroprevalence among the occupationally exposed individuals was 1.41% (95% CI: 00.64-3.12). Seroprevalence was higher among butcher men 5.6% (95% CI: 1.68-5.26), herds men 1.35% (95% CI: 0.18-9.02); and abattoir workers 1.1% (95% CI: 0.26-4.22) although there was no statistical significance. (P value = .18). Seroprevalence was also higher among men (1.8%) compared to females (0%) (P value = .19). and also, among those aged < 11 years (2.5%). Individuals who consumed raw milk had a higher seroprevalence (1.56%) compared to those who drunk boiled milk while seropositivity was 0.88% among those who assisted animals during parturition (P value = .49). Butcher men were at higher risk of exposure compared to other occupational categories. Our findings show the presence of brucellosis in occupationally exposed individuals in Mbeya region.Conclusion: There is need to sensitize the concerned professions in order to reduce the risk of acquiring Brucella infections from animals and animal products This also calls for public health awareness about the disease, and implementation of measures to prevent further spread of brucellosis within and outside the study area.

scholarly journals A Study on Risk Taking Behaviour among Adolescents and Their Attachment with Parents and Peers

2016 ◽  
Vol 3 (4) ◽  
Author(s):  
Uzaina ◽  
Dr. Anupama Srivastava
Keyword(s):  
Substance Use ◽  
Undergraduate Students ◽  
Risk Taking ◽  
Parenting Practices ◽  
Peer Pressure ◽  
Peer Attachment ◽  
Parental Relationship ◽  
Sexual Activities ◽  
The Status ◽  
Attachment Level

The present study examined the role of attachment level of adolescents with parents and peers and their indulgence in risk taking behaviour. Several studies have been reviewed on parental relationship with adolescents and adolescents risk taking behaviour. Researches over last few years have shown that indulgence of adolescents in risk taking behaviour and sexual activities is due to poor parenting practices and one of the prevailing factors is peer attachment. Since no studies related to attachment level of adolescents with parents and indulgence of adolescents in risk taking behaviour have been reviewed in Indian context. Thus to see the status of parent and peer attachment and risk taking behaviour among adolescents, this study was done on a sample of 100 undergraduate students that comprise of 50 males and 50 females. The results showed that females were more attached with their parents and peers in comparison to males. Risk taking behaviour and sexual activities were found to be higher among males than females. It was found that in females the desire of indulging in substance use and sexual activity was low as compared to males. First time indulgence in such behaviour was reported in presence of peers and due to peer pressure. Males reported that they faced ridicule because of not engaging in sexual activities and substance use. Thus positive peer pressure was found helpful in keeping females away from risk taking behaviour.

scholarly journals Endovascular Versus Open Versus Hybrid Revascularisation In Infra Inguinal Disease – 2 Years Prospective Study in A Tertiary Care Center in South India

2020 ◽  
Vol 11 (SPL2) ◽  
pp. 97-101
Author(s):  
Senthilnathan T. T. ◽  
Manoj Prabakar R. ◽  
Subramaniyan S. R. ◽  
Marunraj G. ◽  
Saravanan B. ◽  
...  
Keyword(s):  
Risk Factors ◽  
Prospective Study ◽  
Statistical Significance ◽  
Care Center ◽  
Tertiary Care ◽  
Individual Risk ◽  
P Value ◽  
Acute Limb Ischemia ◽  
Number Of Patients ◽  
Treatment Procedures

Our aim is to share the clinical experience of , open and combined hybrid in infra inguinal disease and compare the results. A prospective study of 150 patients undergoing infra inguinal procedures was done, a period ranging from October 2017 to June 2019 with 3 months follow up. A number of patients undergoing CT , Digital Subtraction (DSA) were recorded. A number of cases undergoing Angioplasty, Catheter Directed (CDT), Open Surgical Bypass were noted. Cases of acute limb ischemia were excluded and chronic cases included in our study, age 35-85 years, sex distribution male 134(89.3%) and female 16(10.7%) cases. Similarly, individual risk factors were stratified. Ct was done in 60 (40%) and DSA in 90 (60%) cases. Diagnostic variables : left occlusion 42 (28%), right occlusion 55(36.7%), left tibial occlusion 18 (12%) and right tibial occlusion 35(23.3%). Treatment procedure variables : CDT and Angioplasty 1(0.7%), angioplasty 87(58%), angioplasty and bypass 8(5.3%), bypass 35(23.3%), CDT 15 (10%), CDT and bypass 4(2.7%). The results of the analysis were compared and statistical significance P-value were calculated by chi-square tests, SPSS software. Statistic significance was seen for risk factors CAD (0.001), Smoking (0.008), Hypertension (0.000) on comparison to treatment procedures and for corresponding clinical diagnosis (0.002), investigation modality (0.000) and treatment procedures.

scholarly journals Knowledge Of Glaucoma And Associated Factors Among Adults In Gish Abay Town, Northwest Ethiopia, Jun 2018

2019 ◽  
Author(s):  
Zewdu Yenegeta Bizuneh ◽  
Ayanaw Tsega ◽  
Yezinash Addis ◽  
Fisseha Admassu
Keyword(s):  
Associated Factors ◽  
Public Health Problem ◽  
Educational Status ◽  
Northwest Ethiopia ◽  
Good Knowledge ◽  
P Value ◽  
Global Public Health ◽  
Binary Logistic Regression Model ◽  
Younger Age ◽  
Eye Examination

Abstract Introduction: Glaucoma is a global public health problem and it is the leading cause of irreversible blindness worldwide and the fifth cause of blindness in Ethiopia. Even though public knowledge of glaucoma is a key for early case identification and prevention of blindness, it is unknown in the study area, making provision of interventions difficult. Objective: To assess knowledge of glaucoma and associated factors among adults in Gish Abay town, Northwest Ethiopia, 2018 Methods: A Community based cross - sectional study design with systematic random sampling technique was used to select 630 adults. The study was conducted from April 25-May 05, 2018. Data was entered into Epi Info version 7 and was analysed by Statistical Package for Social Sciences version 23. Binary logistic regression model and adjusted odds ratio with 95% confidence level was used to identify the significant factors associated with knowledge of glaucoma. P–value ≤ 0.05 was considered statistically significant. Results: About 594 adults were participated with a response rate of 94%. Nearly 52% of the participants were females with median age of 28 years. The proportion of good knowledge was demonstrated in 68.9% [95% CI; 61, 75.9]. Educational status: secondary education [AOR; 4.01: 1.15, 13.94], college and above [AOR; 4.49: 1.31, 15.32], history of eye examination [AOR; 2.86: 1.05, 7.79] and younger age (18-22) [6.39: 1.82, 22.41] were positively associated with good knowledge of glaucoma. Conclusion and recommendation: The proportion of good knowledge of glaucoma was high. Better educational status, younger age, eye examination at least once in life and higher income level were associated with better knowledge of glaucoma. Recognizing the severity of glaucoma, enhancing knowledge is paramount at the community.

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