scholarly journals Joint spatial mapping of childhood anemia and malnutrition in sub-Saharan Africa: a cross-sectional study of small-scale geographical disparities

2019 ◽  
Vol 19 (3) ◽  
pp. 2692-2712
Author(s):  
Rasheed A Adeyemi ◽  
Temesgen Zewotir ◽  
Shaun Ramroop
Keyword(s):  
Risk Factors ◽  
Burkina Faso ◽  
Univariate Analysis ◽  
Sub Saharan Africa ◽  
Deficiency Anemia ◽  
Small Scale ◽  
Cross Sectional ◽  
Geographical Variations ◽  
Childhood Anemia ◽  
Sub Saharan

Background: In epidemiological studies, several diseases share common risk factors or co-exist in their spatial prevalence. Disease mapping allows the health practitioners and epidemiologists to hypothesize the disease aetiology and gain better understanding of the geographical prevalence of the disease risks.Objective: This paper investigates the differences in small scale geographical variations and the underlying risk factors of child’s health outcomes (anemia, stunting and wasting) in Sub-Saharan Africa using spatial epidemiology. Method: The study first carried out an independent univariate analysis on each malnutrition indicator to identify underlying risk factors. A multivariate conditional autoregressive prior was explored to jointly model the spatial correlation between the undernutrition indicators and the small area-geographical disparities at sub-national levels in two sub-Saharan African countries.Results: The approach was implemented on data from National cross-sectional household- based demographic and health surveys conducted in 17,307 under-five children in Burkina Faso and Mozambique in 2010-2012. Out of these children, 31.8% are found to be stunted, 15.5% wasted and 30.9% had anemia among Burkina Faso children, while 42.5% of Mozambican children were stunted, 5.9% wasted and 30.9% suffered from iron-deficiency anemia. The multivariate analysis revealed that the spatial prevalence existed across regions in Burkina Faso with geographical variations in stunting estimated as: 0.7549, CI (0.4693, 1.264); wasting 0.9197; (95%CI : 0.535, 1.591)and anemia : 0.734; (0.4606, 1.214). In additin, the spatial correlation between stunting and wasting was negatively correlated: -0.998; 95% CI (-1.000, -0.984), and a perfect negative correlation;(-1) between stunting and anemia, and positive for wasting and anemia: 0.997; (0.978, 1.000). The spatial occurrence across provinces in Mozambique indicated that there was strong positive correlation between stunting and wasting; 0.986; (0.899, 1.000) and a significant negative correlation between stunting and anemia: -0.720, (-0.934, -0.308) and wasting and anemia: -0.640; (-0.903 -0.174) with individual geographical variability in child stunting: 1427, (913.6, 2268); wasting:1751, (1117, 2803) and anemia: 556, (279.5, 978.9). These extra random effect parameters computed in our multivariate approach would outperform a univariate analysis in similar studies. Our model further detected high prevalent of malnutrition and anemia in the northern Burkina Faso, but high anemia prevalent found in central Mozambique, and high stunting and wasting identified Southern Mozambique. In addition, the risk factors of malnutrition and iron deficiency anemia included household poverty, morbidity, short birth interval (less 18 months), breast feeding, antenatal attendance and maternal literacy.Conclusion: The statistical relevance of the identified risk factors in this study is useful to target specific individual interventions and the maps of the geographical inequalities in sub-national region can be used for designing nutrition interventions and allocation of scarce health resources.Keywords: Joint spatial mapping, childhood anemia, malnutrition, sub-Saharan Africa.

scholarly journals The prevalence, awareness, management and control of hypertension in men and women in Benin, West Africa: the TAHES study

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Ileana Desormais ◽  
Salimanou Ariyoh Amidou ◽  
Yessito Corine Houehanou ◽  
Stephan Dismand Houinato ◽  
Gwladys Nadia Gbagouidi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Large Population ◽  
Community Dwelling ◽  
Sub Saharan Africa ◽  
Rural Setting ◽  
World Health ◽  
Cross Sectional ◽  
Men And Women ◽  
Sub Saharan

Abstract Background Due to epidemiological transitions, Sub-Saharan Africa is facing a growing burden of non-communicable diseases, including cardiovascular diseases (CVDs). Among their risk factors, hypertension is a major determinant of CVDs, but the prevalence and level of awareness and management of this condition are poorly studied in African populations. The aim of this study was to determine the prevalence of hypertension and identify its associated risk factors as well as the awareness and management of this condition in a community-dwelling cohort in Benin. Methods A cross-sectional door-to-door study was conducted in the population over the age of 25 years in Tanve, a rural setting in Benin. The questionnaire and anthropometric measurements of the World Health Organization STEPWISE survey were used. Blood pressure was measured using standard procedures. Results The sample included 1777 subjects (60.9% females, mean age was 42.5 ± 16.5 years). The prevalence of hypertension was 32.9%, similar in men (32.8%) and women (33.0%, p = 0.9342). Age and obesity were significantly associated with hypertension. Less than half (42%) of hypertensive people were aware about their condition and only 46.3% of them were treated. Awareness ratios differed between men and women (respectively 32.9% vs. 47.5%; p = 0.0039) and was not influenced by age, education, occupation, marital status or income. Female sex was the only factor associated with better controlled HTN, independent of socio-economic parameters. Conclusion This large population-based study confirms the high prevalence, low awareness, and low control of hypertension in men and women in sub-Saharan Africa. Only half of the populations with hypertension are aware of their hypertension, indicating a high burden of undiagnosed and un-controlled high blood pressure in these populations.

scholarly journals Association of high-sensitivity C-reactive protein with cardiometabolic risk factors and micronutrient deficiencies in adults of Ouagadougou, Burkina Faso

2012 ◽  
Vol 109 (7) ◽  
pp. 1266-1275 ◽  
Author(s):  
Augustin N. Zeba ◽  
Hélène F. Delisle ◽  
Clémentine Rossier ◽  
Genevieve Renier
Keyword(s):  
Risk Factors ◽  
Burkina Faso ◽  
Cardiometabolic Risk ◽  
High Sensitivity ◽  
Sub Saharan Africa ◽  
Micronutrient Deficiencies ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Sub Saharan ◽  
Hs Crp

Increasing evidence suggests that high-sensitivity C-reactive protein (hs-CRP) is associated with cardiometabolic risk factors (CMRF) while being also related to micronutrient deficiencies. As part of a project on the double burden of under- and overnutrition in sub-Saharan Africa, we assessed the relationship between hs-CRP and both CMRF and micronutrient deficiencies in a population-based cross-sectional study carried out in the Northern district of Ouagadougou, the capital city of Burkina Faso. We randomly selected 330 households stratified by income tertile. In each income stratum, 110 individuals aged 25–60 years and having lived in Ouagadougou for at least 6 months were randomly selected, and underwent anthropometric measurements and blood sample collection. The prevalence of high hs-CRP was 39·4 %, with no sex difference. Vitamin A-deficient subjects (12·7 %) exhibited significant risk of elevated hs-CRP (OR 2·5;P= 0·015). Serum ferritin was positively correlated with log hs-CRP (r0·194;P= 0·002). The risk of elevated hs-CRP was significant in subjects with BMI ≥ 25 kg/m2(OR 6·9; 95 % CI 3·6, 13·3), abdominal obesity (OR 4·6; 95 % CI 2·2, 7·3) and high body fat (OR 10·2; 95 % CI 5·1, 20·3) (P< 0·001, respectively). Independent predictors of hs-CRP in linear regression models were waist circumference (β = 0·306;P= 0·018) and serum TAG (β = 0·158;P= 0·027). In this sub-Saharan population, hs-CRP was consistently associated with adiposity. Assuming that plasma hs-CRP reflects future risk of cardiovascular events, intervention which reduces CRP, or chronic and acute nutrition conditions associated with it, could be effective in preventing their occurrence particularly in sub-Saharan Africa.

scholarly journals The Prevalence, Awareness, Management and Control of Hypertension in Men and Women in Benin, West Africa: the TAHES study.

2019 ◽  
Author(s):  
ILEANA DESORMAIS ◽  
Salimanou Ariyoh Amidou ◽  
Yessito Corine Houehanou ◽  
Stephan Dismand Houinato ◽  
Gwladys Nadia Gbagouidi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Large Population ◽  
Community Dwelling ◽  
Sub Saharan Africa ◽  
Rural Setting ◽  
World Health ◽  
Cross Sectional ◽  
Men And Women ◽  
Sub Saharan

Abstract Background Sub-Saharan Africa is facing a growing burden of non-communicable diseases, including cardiovascular diseases (CVDs), due to epidemiological transitions. Among their risk factors, hypertension is a major determinant of CVDs, but the prevalence and level of awareness and management of this condition are poorly studied in African populations. The aim of this study was to determine the prevalence of hypertension and identify its associated risk factors as well as the awareness and management of this condition in a community-dwelling cohort in Benin. Methods A cross-sectional door-to-door study was conducted in the population over the age of 25 years in Tanve, a rural setting in Benin. The questionnaire and anthropometric measurements of the World Health Organization STEPWISE survey were used. Blood pressure was measured using standard procedures. Results The sample included 1777 subjects (60.9% females, mean age was 42.5±16.5 years). The prevalence of hypertension was 32.9%, similar in men (32.8%) and women (33.0%, p=0.9342). Age and obesity were significantly associated with hypertension. Less than half (42%) of hypertensive people were aware about their condition and only 46.3% of them were treated. Awareness ratios differed between men and women (respectively 32.9% vs. 47.5%; p= 0.0039) and was not influenced by age, education, occupation, marital status or income. Female sex was the only factor associated with better controlled HTN, independent of socio-economic parameters. Conclusion This large population-based study confirms the high prevalence, low awareness, and low control of hypertension in men and women in sub-Saharan Africa. Only half of the populations with hypertension are aware of their hypertension, indicating a high burden of undiagnosed and un-controlled high blood pressure in these populations.

scholarly journals PO 8458 POLYMORPHISM OF THE PLASMODIUM FALCIPARUM MSP-2 GENE ASSOCIATED WITH PLACENTAL MALARIA AT THE BORGOU-ALIBORI DEPARTMENTAL HOSPITAL

2019 ◽  
Vol 4 (Suppl 3) ◽  
pp. A40.1-A40
Author(s):  
Dossou Akpéyédjé ◽  
Saadou Issifou
Keyword(s):  
Plasmodium Falciparum ◽  
Univariate Analysis ◽  
Placental Malaria ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Allelic Polymorphism ◽  
Cross Sectional ◽  
Major Health Problem ◽  
Prenatal Consultation ◽  
Sub Saharan

BackgroundIn sub-Saharan Africa, malaria during pregnancy is a major health problem because it poses significant risks for the pregnant woman and the foetus. The sequestration of Plasmodium falciparum-infected erythrocytes in the placenta has consequences for the mother and the foetus. This study aimed to evaluate the allelic polymorphism of the Plasmodium falciparum MSP-2 gene related to the consequences of placental malaria.MethodsIt was a cross-sectional study conducted over two periods lasting six months in 2016 and 2017. The maternity center of the Hospital of Borgou-Alibori in Benin served as a framework for the study. From the 98 parturients included, placental blood samples were taken and then genotyped.ResultsUsing the MSP-2 gene as marker, the prevalence was 17, 34%. The MSP-2 gene was polymorphic with 9 distinct allelic types for both 3D7 and FC27 families (150 bp; 200 bp; 250 bp; 275 bp; 300 bp; 350 bp; 400 bp; 450 bp and 500 bp). The FC27 allelic family was predominant over the 3D7 family with 56, 25% and 43, 75% respectively. The 300 bp allelic type (50%) was predominant in the FC27 family while the 400 bp type was predominant in 3D7 family (35, 71%). 9 women had polyclonality (52,94%). The multiplicity of infection (MOI) was 1, 88. The number of strains ranged 1 to 4 in infected women. In univariate analysis there was no significant relationship between MSP-2 gene polymorphism and maternofoetal consequences. The absence of „prenatal consultation (p=0.0270), non-taking of IPTp/SP (p=0.0060), the occurrence of malaria in the third trimester (p=0,0364) and moderate maternal anaemia (p=0.0277) were associated with the polymorphism of MSP-2 gene. The MOI was significantly associated with parasite density of infected women.ConclusionPlasmodium falciparum MSP-2 gene was polymorphic in infected women at Parakou. Several factors related to pregnancy monitoring were associated with this genetic diversity. It is therefore essential to ensure correct follow-up of pregnancies.

scholarly journals Kidney damage and associated risk factors in rural and urban sub-Saharan Africa (AWI-Gen): a cross-sectional population study

2019 ◽  
Vol 7 (12) ◽  
pp. e1632-e1643 ◽  
Author(s):  
Jaya A George ◽  
Jean-Tristan Brandenburg ◽  
June Fabian ◽  
Nigel J Crowther ◽  
Godfred Agongo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Population Study ◽  
Kidney Damage ◽  
Sub Saharan Africa ◽  
Cross Sectional ◽  
Rural And Urban ◽  
Sub Saharan ◽  
Associated Risk Factors

scholarly journals Prevalence of active convulsive epilepsy in sub-Saharan Africa and associated risk factors: cross-sectional and case-control studies

2013 ◽  
Vol 12 (3) ◽  
pp. 253-263 ◽  
Author(s):  
Anthony K Ngugi ◽  
Christian Bottomley ◽  
Immo Kleinschmidt ◽  
Ryan G Wagner ◽  
Angelina Kakooza-Mwesige ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Control ◽  
Sub Saharan Africa ◽  
Case Control Studies ◽  
Cross Sectional ◽  
Sub Saharan ◽  
Associated Risk Factors

scholarly journals Once The Eldery, Now The Youth : Epidemiological Study Of Non-Communicable Diseases Among Children Under 15 Years Of Age In Yaoundé-Cameroon

2020 ◽  
Vol 2 (2) ◽  
Author(s):  
Blaise Nguendo Yongsi
Keyword(s):  
Risk Factors ◽  
Low Income ◽  
Disease Burden ◽  
Medical Condition ◽  
Communicable Diseases ◽  
Sub Saharan Africa ◽  
Cross Sectional ◽  
Non Communicable Diseases ◽  
Primordial Prevention ◽  
Sub Saharan

Background: In sub-Saharan Africa, communicable diseases have long been among the most prominent contributors to disease burden. However, like most low-income and middle-income countries across the globe, countries in sub-Saharan Africa are experiencing a shift from disease-burden profiles dominated by communicable diseases and childhood illnesses to profiles featuring an increasing predominance of chronic, non-communicable diseases (NCDs). Objective : The main objective of this study is to investigate the magnitude of non-communicable chronic diseases at the Chantal Biya Foundation in Yaoundé. Design and participants: This is an institution-based and cross-sectional study conducted from january to december 2018. Participants were in and out patients who visited the institution and whose a medical condition was clearly diagnosed. Results : Of the 643 medical records, leading causes of visit were infectious diseases (51.1%), followed by NCDs (48.9%). Diagnosed NCDs range from sickle cell disease (5.7%), injuries (9.8%), cardiovascular diseases (12.0%), to cancers (25.0%). Conclusion There is a significant burden of NCDs among adolescents in Yaoundé. Then, interventions for primordial prevention (ie, actions to inhibit the emergence of NCD risk factors) and primary prevention (ie, actions on existing NCD risk factors), as well as educational programmes on leading modifiable behavioural risk factors and metabolic risk factors are crucial.

scholarly journals Prevalence and Risk Factors of Schistosoma Mansoni Infection Among Preschool-Aged Children From Panamasso Village, Burkina Faso

2021 ◽  
Author(s):  
Mamoudou Cisse ◽  
Ibrahim Sangare ◽  
Arthur D. Djibougou ◽  
Marc C. Tahita ◽  
Souleymane Gnissi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Burkina Faso ◽  
Control Strategies ◽  
Point Of Care ◽  
Geometric Mean ◽  
Sub Saharan Africa ◽  
Health Concern ◽  
Water Contact ◽  
Cross Sectional ◽  
Preschool Aged Children

Abstract BackgroundSchistosomiasis remains a major public health concern in sub-Saharan Africa. Although schistosomiasis is well documented in school-aged children in Burkina Faso, prevalence data among preschool-aged children (PSAC) are limited and outdated, and its risk factors in this group remain poorly documented. The main objective of this study was to assess the prevalence and risk factors associated with Schistosoma (S.) mansoni infection among PSAC from Panamasso village, western Burkina Faso.MethodologyA cross-sectional study was carried out among 228 children under 6 years old from Panamasso village. Sociodemographic and water contact data were collected using a structured questionnaire. Kato-Katz and formol-ether concentration techniques were used to detect S. mansoni eggs in stool samples. Urine samples were subjected to a point-of-care circulating cathodic antigen (POC-CCA) cassette test and a centrifugation method to check for both S. mansoni and S. haematobium infection, respectively. Potential risk factors for S. mansoni infection were explored using multivariable logistic regression.ResultsThe mean age of children was 40.2 ± 15.0 months. The prevalence of S. mansoni infection as determined by Kato-Katz, formol-ether concentration, and POC-CCA was 42.1%, 39.5% and 80.7%, respectively. Based on the combined results of the three methods, the overall prevalence of S. mansoni infection was 81.1%. No case of S. haematobium infection was found. The geometric mean intensity of S. mansoni infection was 107.2 eggs per gram of faeces with 54.2%, 33.3%, and 12.5% of the children having light, moderate, and heavy infections, respectively. Girls (AOR = 2.9, 95% CI: 1.3-6.1), a household located within 500 m from the pond (AOR = 3.0, 95% CI: 1.0-8.6), or between 500 and 1000 m from the pond (AOR = 3.0, 95% CI: 1.2-7.2), and child’s history of going to the pond (AOR = 5.0, 95% CI: 1.7-14.3) were the variables significantly associated with S. mansoni infection. ConclusionS. mansoni was the sole species infecting a high proportion of PSAC in the study area. A mass drug administration program with praziquantel is therefore urgently required for those below 6 year-old. Other control strategies should include increased community-awareness and provision of safe water.

scholarly journals Prevalence of Diabetes and Associated Risk Factors among a Group of Prisoners in the Yaoundé Central Prison

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Sylvain Raoul Simeni Njonnou ◽  
Jérôme Boombhi ◽  
Martine Claude Etoa Etoga ◽  
Aimée Tiodoung Timnou ◽  
Ahmadou Musa Jingi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Sedentary Lifestyle ◽  
Univariate Analysis ◽  
International Diabetes Federation ◽  
Public Health Problem ◽  
Cross Sectional Study ◽  
Sub Saharan Africa ◽  
Cross Sectional

Background. Diabetes is a public health problem worldwide, associated with increased morbidity and mortality. According to the International Diabetes Federation (IDF) 2017 data, around 425 million people worldwide suffer from diabetes. This number is expected to increase to 629 million in 2045. Various occidental studies reported the increased prevalence and lower control of diabetes among prisoners. However, there is no data on the characteristics of inmates with diabetes in sub-Saharan Africa. Methods. A cross-sectional study among incarcerated detainees from the Yaoundé Central Prison was conducted from January to July 2017. Diabetes was defined according to the American Diabetes Association (ADA) criteria. Analyzed variables included phenotypic characteristics, lifestyle, the reason for detention, the sentence severity, and the length of detention. Results. We recruited 437 inmates (344 men) with an average age of 37.0 (95% CI: 35.9-38.3) years. The most frequent age group was 20 to 39 years with 281 (64.7%) inmates, and the mean prison stay was 29.1 (95% CI: 25.7-32.8) months. The prevalence of diabetes in the Yaoundé Central Prison was 9.4%. The main cardiovascular risk factors were a sedentary lifestyle (91.1%), hypertension (39.6%), smoking (31.6%), and alcohol consumption (28.1%). Hypertension (p=0.005), obesity (p=0.0006), smoking (p=0.04), sedentary lifestyle (p=0.04), major crime (p=0.007), and minor crime (p=0.003) were associated with diabetes in univariate analysis. In multivariate analysis, only obesity and sedentary lifestyle were associated with diabetes. Conclusion. Diabetes prevalence in the Yaoundé Central Prison was high, at 9.4%, compared to that in the general population. It was associated with other classical cardiovascular risk factors and factors linked to the sentence (minor and major crimes). This trial is registered with CE00617/CRERSHC/2016.

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