scholarly journals Some Traits on the Outcome of the Treatment of Cervical Cancer in Tanzania: A Case Study of Ocean Road Cancer Institute (ORCI)

2020 ◽  
Vol 21 (2) ◽  
pp. 1-9
Author(s):  
Bakari L Leguma ◽  
Rajabu Rocky Akarro ◽  
Amina Suleiman Msengwa ◽  
Francis Joseph Sichona

Background: In Tanzania, like in many other poor African countries, cervical cancer is a major problem facing women especially for those aged 30 years and above. This study aimed at constructing a statistical model to enable the prediction of the outcome of treatment for cervical cancer patients in Tanzania. Methods: Data were collected retrospectively from patient’s files with histological proven cervical cancer who were treated at Ocean Road Cancer Institute (ORCI) from year 2009 and followed up to year 2011. The factors considered are screening status, HIV status, disease stage, age, treatment type and the intent of the treatment. The study employed the Chi-square (χ2) test and the logistic regression model for its analysis. Results:  The Chi-square (χ2) test result showed that there was a significant relationship between outcome of treatment and the patient screening status, HIV status, disease stage and intent of treatment at 5% level of significance. On the other hand, the logistic regression results found patient disease stage and intent of the treatment to be statistically significant at 95 percent. Logistic regression results also showed that patients who attended ORCI when their disease at a late stage had an odds ratio of 0.128 less likely to have favorable outcomes compared to those patients who attended ORCI when their disease stage was at early stages. The odds ratio for cervical cancer patients who received both treatment, radiotherapy, and chemotherapy was 2.643 more likely to have favorable outcomes Conclusion:  More emphasis and campaigns should be made in order to encourage women all over the country to attend cancer centers for screening and treatment at early stages or even before any symptoms for cervical cancer and other types of cancers.

Author(s):  
Jorge Nelson da Silva Júnior ◽  
Rafael Lima Kons ◽  
Rodolfo André Dellagrana ◽  
Daniele Detanico

This study aimed to identify types and sites of body injury, location of injury occurrence, and the mechanism and severity of injuries in novice and advanced Brazilian jiu-jitsu (BJJ) athletes. One hundred and eight BJJ athletes took part in this study separated in two groups: advanced (n = 53) and novice (n = 55). Athletes answered a questionnaire concerning regions of injury, locality of occurrence, injury severity and mechanism. Chi square test and a logistic regression analysis were used with the level of significance set at p < 0.05. The main results showed that shoulders and knees were the most injury location reported by novice and advanced athletes. Novice athletes demonstrated higher prevalence of injuries during training sessions (54.5%), whereas advanced athletes reported more injuries during competitions (66.1%). Significant associations between novice and advanced athletes were observed for major joints (p < 0.05). The odds ratio of having injury was 70-87% less for novice versus advanced athletes for the major joints cited. We concluded that BJJ athletes demonstrate high prevalence of injury mainly at knee and shoulder. While risk of injury appeared less in novice, the advanced demonstrated higher number of injuries during competitions as a consequence of injured joint keys. By contrast, novice athletes reported higher number of injuries associated with training sessions as a consequence of overuse.


2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Rohini K. Bhatia ◽  
Mohan Narasimhamurthy ◽  
Yehoda M. Martei ◽  
Pooja Prabhakar ◽  
Jeré Hutson ◽  
...  

Abstract Background To characterize the clinico-pathological features including estrogen receptor (ER), progesterone receptor (PR) and Her-2/neu (HER2) expression in breast cancers in Botswana, and to compare them by HIV status. Methods This was a retrospective study using data from the National Health Laboratory and Diagnofirm Medical Laboratory in Gaborone from January 1, 2011 to December 31, 2015. Clinico-pathological details of patients were abstracted from electronic medical records. Results A total of 384 unique breast cancer reports met our inclusion criteria. Of the patients with known HIV status, 42.7% (50/117) were HIV-infected. Median age at the time of breast cancer diagnosis was 54 years (IQR 44–66 years). HIV-infected individuals were more likely to be diagnosed before age 50 years compared to HIV-uninfected individuals (68.2% vs 23.8%, p < 0.001). The majority of patients (68.6%, 35/51) presented with stage III at diagnosis. Stage IV disease was not presented because of the lack of data in pathology records surveyed, and additionally these patients may not present to clinic if the disease is advanced. Overall, 68.9% (151/219) of tumors were ER+ or PR+ and 16.0% (35/219) were HER2+. ER+ or PR+ or both, and HER2- was the most prevalent profile (62.6%, 132/211), followed by triple negative (ER−/PR−/HER2-, 21.3%, 45/211), ER+ or PR+ or both, and HER2+, (9.0%, 19/211) and ER−/PR−/HER2+ (7.1%, 15/211). There was no significant difference in receptor status noted between HIV-infected and HIV-uninfected individuals. Conclusions Majority of breast cancer patients in Botswana present with advanced disease (stage III) at diagnosis and hormone receptor positive disease. HIV-infected breast cancer patients tended to present at a younger age compared to HIV-uninfected patients. HIV status does not appear to be associated with the distribution of receptor status in breast cancers in Botswana.


1995 ◽  
Vol 31 ◽  
pp. S45
Author(s):  
N. Potić-Zečcević ◽  
Z. Stanojević ◽  
M. Milutinović ◽  
S. Filipović ◽  
B. Djordjević

2018 ◽  
Vol 37 (2) ◽  
Author(s):  
Lukmanulhakim Lukmanulhakim ◽  
Lenny Stia Pusporini

Abstract: Competence test is conducted to fulfil the graduates’ performance competence standards. Nurse competence is oriented to the performance quality in giving a comprehensive care. Study intends to identify factors influencing graduation achievement in UKNI of Nurse Profession Program students of STIKes Faletehan Serang. It is a quantitative study with analytical correlational design and cross sectional approach. Samples are 106 respondents who were selected by using total sampling technique. The statistical used are Chi Square and simple logistic regression prediction model. The Chi Square analysis result with α = 0.05 finds p value of the three variables are 0.804 (anxiety and family support), and 1.000 (peers support). Besides, the analysis result of other three variables obtains p value of 0.034 (GPA), p value of 0.000 (liveliness), and p value of 0.000 (try out result). The analysis result of simple logistic regression shows that Odds Ratio (OR) of liveliness variable is 156.734. The research results can be an evaluation material to increase graduation achievement in UKNI are the benchmark of improving the implementation of university quality assurance. Keywords: capaian kompetensi, kompetensi perawat, uji kompetensi Ners, progra profesi Ners ANALISIS FAKTOR YANG MEMPENGARUHI CAPAIAN KELULUSAN UJI KOMPETENSI NERS MAHASISWA PROGRAM PROFESI NERS  Abstrak: Uji kompetensi dilaksanakan untuk mencapai lulusan yang memenuhi standar kompetensi kinerja. Kompetensi perawat berorientasi terhadap kualitas kinerja dalam memberikan pelayanan keperawatan secara komprehensif.Penelitian bertujuan untuk mengetahaui faktor-faktor yang mempengaruhi capaian kelulusan UKNI mahasiswa Program Profesi Ners STIKes Faletehan Serang. Penelitian berjenis kuantitatif dengan rancangan korelasi analitik melalui pendekatan Cross Sectional.Sampel penelitian sebanyak 106 responden yang diambil dengan teknik total sampling. Data dikumpulkan lewat angket. Analisis data dilakukan dengan menggunakan Chi Square dan regresi logistik sederhana model prediksi.Hasil analisis uji Chi Square dengan α = 0.05, ketiga variabel diperoleh p value sebesar 0,804 (kecemasan dan dukungan keluarga), serta 1,00 (dukungan teman sebaya). Hasil analisis ketiga variabel lainnya diperoleh p value sebesar 0.034(IPK Akademik), 0.000 (keaktfikan), dan 0.000 (try out nasional). Hasil analisis regresi logistik, teridentifikasi Odds-Ratio (OR) dari variabel keaktifan adalah 156.734.Hasil ini dapat dijadikan evaluasi dalam peningkatan capaian kelulusan UKNI yang merupakan tolak ukur dalam penyelenggaraan penjaminan mutu perguruan tinggi. Kata kunci : capaian kompetensi, kompetensi perawat, uji kompetensi Ners, progra profesi Ners


2020 ◽  
Vol 2 (1) ◽  
pp. 352-356
Author(s):  
Vani Olin Arysha ◽  
Heru Santosa ◽  
Sri Rahayu Sanusi

Cervical cancer is a cancer that attacks many women. The high number of cervical cancer sufferers in Indonesia is caused by only 5% who screen for cervical cancer, because this disease does not cause symptoms and low awareness of women to check their health. Every woman of childbearing age should be motivated to do an IVA Test. The purpose of this study is to analyze the effect of extrinsic motivation on housewives actions in IVA Test. The design of this study is a case control with 36 samples in cases and controls. Processing data using chi square analysis with a 95% significance level by calculating the odds ratio. The results showed that there was an influence of extrinsic motivation (p = 0,000) on the housewives actions in IVA Test. The results of the analysis showed that the OR 10.969 95% CI (3.425-35.129) that did Possible IVA Test 10.9 is more effect than housewives who have extrinsic motivation.


2020 ◽  
Vol 30 (5) ◽  
pp. 613-618
Author(s):  
Mario Jesus Trejo ◽  
Kennedy Lishimpi ◽  
Mulele Kalima ◽  
Catherine K Mwaba ◽  
Lewis Banda ◽  
...  

IntroductionSub-Saharan Africa has the highest global incidence of cervical cancer. Cervical cancer is the most common cause of cancer morbidity and mortality among women in Zambia. HIV increases the risk for cervical cancer and with a national Zambian adult HIV prevalence of 16%, it is important to investigate the impact of HIV on the progression of cervical cancer. We measured differences in cervical cancer progression between HIV-positive and HIV-negative patients in Zambia.MethodsThis study included 577 stage I and II cervical cancer patients seen between January 2008 and December 2012 at the Cancer Diseases Hospital in Lusaka, Zambia. The inclusion criteria for records during the study period included known HIV status and FIGO stage I and II cervical cancer at initial date of registration in the Cancer Diseases Hospital. Medical records were abstracted for clinical and epidemiological data. Cancer databases were linked to the national HIV database to assess HIV status among cervical cancer patients. Logistic regression examined the association between HIV and progression, which was defined as metastatic or residual tumor after 3 months of initial treatment.ResultsA total of 2451 cervical cancer cases were identified, and after exclusion criteria were performed the final analysis population totaled 537 patients with stage I and II cervical cancer with known HIV status (224 HIV-positive and 313 HIV-negative). HIV-positive women were, on average, 10 years younger than HIV-negative women who had a median age of 42, ranging between 25 and 72. A total of 416 (77.5%) patients received external beam radiation, and only 249 (46.4%) patients received the recommended treatment of chemotherapy, external beam radiation, and brachytherapy. Most patients were stage II (85.7%) and had squamous cell carcinoma (74.7%). HIV-positive patients were more likely to receive lower doses of external beam radiation than HIV-negative patients (47% vs 37%; P<0.05, respectively). The median total dose of external beam radiation for HIV-positive and HIV-negative patients was 46 Gy and 50 Gy, respectively. HIV positivity did not lead to tumor progression (25.4% in HIV-positive vs 23.9% in HIV-negative, OR 1.04, 95% CI [0.57, 1.92]). However, among a subset of HIV-positive patients, longer duration of infection was associated with lower odds of progression.ConclusionThere was no significant impact on non-metastatic cervical cancer progression by HIV status among patients in Lusaka, Zambia. The high prevalence of HIV among cervical cancer patients suggest that HIV-positive patients should be a primary target group for HPV vaccinations, screening, and early detection.


Author(s):  
Heriberto Janosch González ◽  
Francisco Pérez Fernández ◽  
Juan Enrique Soto Castro

En el presente estudio pretendimos analizar las características de los autores de agresiones sexuales cuyo modus operandi es el de atacar a la víctima en portales o entradas de garaje de edificios. Nuestro estudio estuvo orientado a determinar si es posible predecir tales características a partir de los datos de la escena del crimen, analizando casos resueltos. Partiendo del contenido de sentencias judiciales condenatorias dictadas en España, y aplicando pruebas estadísticas de chi-cuadrado, odds-ratio, y regresión logística binaria, hemos obtenido resultados alentadores, en el sentido de que algunas de las variables de la escena del crimen permiten predecir algunas características de los autores. Dado que las variables de la escena del crimen utilizadas aquí son conocidas por el equipo policial al inicio de la investigación, la predicción de características del agresor sexual podría ser de utilidad a la hora de priorizar sospechosos.This paper aims at analysing the features of the perpetrators of sexual assaults whose modus operandi consists of assaulting the victim in doorways or entrances of garage and buildings. Its objective was to determine whether it is possible to predict these features moving from the information regarding the crime scene, by means of analysing solved cases. Moving from the content of convicting judgments issued in Spain, and by applying statistical tests of chi-square, odds-ratio, and binary logistic regression, we have obtained encouraging results, in that some variables in the crime scene allow to predict some features of these offenders. Since the variables of the crime scene that have been used here are known to the police team at the beginning of the investigation, prediction of the sexual offender’s features could be useful to prioritize suspects.


2020 ◽  
Vol 4 (Supplement_2) ◽  
pp. 1131-1131
Author(s):  
Nankun Liu ◽  
Alexander Hien Vu ◽  
David Seres ◽  
Max Shen

Abstract Objectives The association between inflammation, malnutrition, and cancer is not well understood. The aim of this study was to examine the association between inflammatory-type cancer and diagnosed malnutrition, albumin level, and age in patients with cancer. Methods Malnutrition and cancer diagnoses were obtained using data from hospital medical records in patients admitted for cancer between Oct. 2017 and Dec. 2018. Demographics, as well as the first and lowest albumin levels were also obtained. A simple t-test is processed between age and malnutrition status. Also a chi-square test of independence was performed to examine the relation between malnutrition and hypoalbuminemia status. Logistic regression was conducted between malnutrition status, sarcoma cancer, age, and hypoalbuminemia. Results The study included 4034 patients (2084 males, 1949 females). Approximately 4% of the patients were diagnosed with malnutrition. Logistic regression on malnutrition status, sarcoma, age, and hypoalbuminemia showed a significant association on global test (3, 2433, P-value = 0.013). Hypoalbuminemia (&lt; 3.9 g/dL lower-limit) was significantly associated with malnutrition (X2 1, 2433 P-value = 0.0156). Sarcoma diagnosis was not significantly associated with malnutrition (X2 1, 2433 P-value = 0.267). Age is not significantly related to malnutrition status (X2 1, 2433 p-value = 0.449). A t-test was also performed malnutrition vs no malnutrition on age, resulting in a marginally significant association for malnutrition group (M = 65.33, SD = 15.50) vs no malnutrition group (M = 67.32, SD = 17.55) (t(1) = 3.7212, P = 0.0537). Conclusions Sarcoma is not significantly associated with an increased risk of malnutrition. Cancer patients with hypoalbuminemia have a higher risk for malnutrition compared to the patients with normal albumin level. Additionally, age may be a predictor for cancer patients’ risk of in-hospital malnutrition. Funding Sources None.


2019 ◽  
Vol 37 (15_suppl) ◽  
pp. e17020-e17020
Author(s):  
Shelby Corman ◽  
Chizoba Nwankwo ◽  
Youngmin Kwon ◽  
Ruchit Shah

e17020 Background: Treatment options for cervical cancer include surgery, radiation therapy, chemotherapy, and immunotherapy depending upon the disease stage. There is limited real-world evidence providing us with a clinical profile for a treated cervical cancer patient. The objective of this study was to compare cervical cancer patients who were currently receiving treatment versus those not receiving treatment. Methods: This was a retrospective, cross-sectional analysis of Medical Expenditure Panel Survey (MEPS) data (2006-2015). Cervical cancer cases were identified using ICD-9 CM code 180 or clinical classification software code 26. Patients receiving only chemotherapy, radiation therapy, undergoing surgery, or a combination of these treatments in a given year were regarded as “currently receiving treatment”. The comparator cohort included patients “not currently receiving treatment”. The two cohorts were compared in terms of patient clinical characteristics using bivariate analyses. Results: The analytic cohort consisted of 275,246 cervical cancer cases (mean age: 42 years, Caucasian: 88.0%, having private insurance: 55.3%) of which 115,639 (42.01%) were “currently receiving treatment”. The most common treatment option was undergoing surgery only (88.21%), followed by combination therapy (6.82%), chemotherapy only (3.84%), and radiation therapy only (1.12%). The “currently receiving treatment” cohort had a significantly higher proportion of patients having a history of myocardial infarction (4.21% vs 3.50%), congestive heart failure (2.73% vs 1.42%), chronic obstructive pulmonary disorder (29.5% vs 23.2%), connective tissue disease (20.5% vs 11.6%), renal disease (2.49% vs 0.48%), and diabetes (17.7% vs 11.7%) compared to those “not currently receiving treatment”. The latter cohort had a higher proportion of patients with moderate/severe liver disease (0.46% vs 5.32%). Conclusions: The observed real-world patient characteristics and treatment patterns were indicative of a cohort of largely early stage cervical cancer patients. Patients receiving treatment appeared to have a higher comorbidity burden which may subsequently result in poorer quality of life and activity limitations.


Author(s):  
Elsa Barber ◽  
Silvia Pisano ◽  
Sandra Romagnoli ◽  
Verónica Parsiale ◽  
Gabriela de Pedro ◽  
...  

This chapter studies user interfaces of Web Online Public Access Catalogs (OPACs) and presents their principal difficulties in facing the man-machine interaction and the contributions of Web 2.0 to overcome these limitations. Methodologies used to study OPACs interfaces are examined. A quantitative approach is used to analyze Web OPACs in academic, special, national, and public libraries through the conclusive use of several tests: chi-square or test of independence, logistic regression, odds ratio, analysis of variance, and discriminant analysis. The situation of Latin American Web OPACs is verified in relation to the use of Integrated Library Systems (ILS) and Database Management Systems (DBMS). This methodology is proposed to study the 2.0 functionalities in these catalogs.


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