Clinical Manifestation and Epidemiological Impacts of Pandemic Zoonotic Disease of the Novel Corona Virus (COVID-19)

2020 ◽  
pp. 1-6
Author(s):  
Firew Admasu Hailu ◽  
◽  
Tsion Admasu Hailu ◽  
Rodas Firew Admasu ◽  
◽  
...  

This study used to address the most organized information about clinical demonstration and epidemiological impacts and the new pandemic zoonotic disease called corona virus. Background: The new respiratory virus known as corona (COVID-19) first originated in China at Wuhan, and rapidly spreading to all worldwide continents. The common cold, SARS, MERS and COVID-19 are types of corona viruses, and most people get infected with one or more of these viruses at some point in their lives. COVID-19 is viruses known for containing strains of lethal diseases in mammals and birds, its infections rate is doubling at every six days, infecting large number of people, its name is given from the protrude spikes surfaces, infect the respiratory tract of animals and human, transmit via droplets and contact. Objectives: The objectives of this study is to address scientific information’s about zoonotic disease called COVID-19, its clinical display like symptoms, ways of transmission, prevention methods, epidemiology and complications. Methods: Observing what is happening in the world, and collecting epidemiological data from WHO about COVID-19, organizing and rewrite in scientific methods. Results and Conclusion: Zoonotic diseases are diseases first transmit from infected animal to humans, animals such as bat, rat, pig, insects, fish, etc. The novel COVID-19 have been first originated in Wuhan from seafood sale market of sells fish, bats, snakes and pangolins and highly spreading globally. It is a pandemic zoonotic disease, infecting every individual of human being at any age, sex, race, religions, lifestyle, educational level, etc. Its similar symptoms with other corona viruses type such as strong fever, high elevated body temperature, dry cough, muscle fatigue, breathing difficulties, etc and also less common symptoms includes coughing mucus or blood, headaches, diarrhea, and kidney failure. In addition, as the disease progresses, patients approach with pneumonia, inflames the lungs and causes alveoli to fill with fluid and this can be detected by an X-ray. Its primary ways of transmission includes respiratory droplets from coughing and sneezing of fluid produced by infected individuals, touching contaminated surfaces, hands and objects with our hands then our mouth, nose and eye. Based on worldwide epidemiological data, more than 2.8 million people were infected, of which about 200,000 were died within 100 days, whereas, about 25 million people were infected, of which more than 846,000 were died within 220 days and also it creates negative economic impacts especially in developing countries. However, till now there is no recognized therapeutic against corona viruses, therefore advisable prevention methods are washing our hands regularly with soap, use hand sanitizer properly, during coughing and sneezing use inside of our elbow, stop handshaking with anyone, stay at home to limit social co

2021 ◽  
Vol 12 (1) ◽  
pp. 118-123
Author(s):  
Onkar Doke ◽  
Anagha Kaldhone ◽  
Rupali Karkar ◽  
Raisa Shaikh ◽  
Salani Sahani

A respiratory infection owing to a novel corona virus was first identified in Wuhan, China in December 2019. World health organization declared name for this novel corona virus as “COVID-19” is now a worldwide pandemic and has been recognized in more than 200 countries. Corona viruses are virus that is known to cause infection varying from the common cold to more critical diseases like Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). It is known to transmit by respiratory droplets released when corona virus patient coughs, sneezes or talks and if another person inhales the droplets or touches these surfaces and further touches his face, eyes or mouth can get an infection. Currently there are no specific vaccines or medicines for Corona virus disease and treatment given based on symptoms. But many vaccines are under investigation.


Author(s):  
Santosh Kumar Singh

Corona viruses are a big family of different viruses. Some of them cause the common cold in people and other infect from animals, like bats, camels and cattle, Corona virus enters in human cells through membrane ACE-2 receptor. WHO and ECDC advised – Avoid public place, follow social distancing and close contact to infected persons and animals. COVID- 19 is a corona series of viruses but it has changed all human life.


2020 ◽  
Vol 6 (2) ◽  
pp. 82-89
Author(s):  
Bhairav Prasad ◽  
Neha Prasad

Coronaviruses are large group of enveloped viruses with unsegmented, single-stranded, positive-sense RNA as genetic material. These are collection related RNA viruses that cause diseases of economically important vertebrate viz. mammals and birds. In humans, these viruses cause respiratory tract infections that can range from asymptomatic to life threatening. The asymptomatic disease include very similar to some cases of the common cold, while other deadly varieties can cause SARS, MERS, and COVID-19. The SARS-CoV (severe acute respiratory syndrome coronavirus) and MERS-CoV (Middle East respiratory syndrome coronavirus) are zoonotic origin and extremely pathogenic coronaviruses that can cause localized and worldwide outbreak. The novel Coronaviruses, COVID-19 posses a unique morphology.  The outer surface of the virus bearing surface spike and reveled like crown hence being named corona virus. The mode of replication of the virus is very unique as it replicate through the generation of nested set of viral mRNA. The HCoV (Human coronavirus) cause respiratory complication with asymptomatic to life threatening outcomes. From the past 15 years we have witnessed appearance of two zoonotic, extremely pathogenic human corona viruses the:  SARS-CoV and MERS-CoV.


2020 ◽  
Vol 6 (2) ◽  
pp. 43-43
Author(s):  
S. Kalimuthu ◽  

Corona viruses are a large family of viruses that are known to cause illness ranging from the common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). A novel corona virus (Co V) is a new strain of corona virus that has not been previously identified in humans. Corona viruses can be transmitted from person to person, usually after close contact with an infected patient. There is no specific treatment for disease caused by a novel corona virus. In this Hypothesis, the author proposes an alternative herbal inhaler, syrup, drug and a vaccine for curing Covid-19.


2021 ◽  
Vol 8 (9) ◽  
pp. 1615
Author(s):  
Sushil Singla ◽  
Mohitesh Kumar ◽  
Yaswanth C. Raavi

The novel corona virus disease (COVID-19) caused by the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) is a global public health concern, primarily transmitted through respiratory droplets; though other routes of transmission are documented but not been fully demonstrated. At risk included all age groups, somehow for reasons unknown infants and children appears to be at a lower risk of severe infection, but recently children with hyper inflammatory syndrome and multi-organ dysfunction associated with COVID-19 have been increasingly reported. We report a case of 31-week neonate of 1.292 kg confirmed with SARS-CoV-2 infection, at birth, born to a COVID positive mother, initially developed respiratory distress at birth and abrupt progression to severe distress and later developed pneumothorax and hyper-inflammation (MIS-N). Respiratory support, corticosteroids, enoxaparin, antimicrobials, and other preterm care were given, and finally recovered and discharged after 30 days (1.812 kg). This case highlights the severe presentation of COVID-19 in a pre-term neonate. To the best of our knowledge this is apparently the youngest covid survivor till date reported in world. Clinical data on COVID-19 in new-born is extremely limited, so it is important to understand that these conclusions are based on limited data and our understanding will continue to evolve. 


Coronaviruses ◽  
2020 ◽  
Vol 01 ◽  
Author(s):  
Tinsae Kebede ◽  
Dharmendra Kumar ◽  
Pramod Kumar Sharma

: Corona viruses belong to the largest group of viruses that elicits acute respiratory, enteric and systemic infections in an extensive range of hosts. A few corona viruses from animals can progress into a new human corona virus that can spread from person to person. On February 12, 2020, WHO officially termed the disease as Corona Virus Disease 2019 (COVID-19) and declared as a pandemic on March 11, 2020. COVID-19 is a new emerging viral disease that has an effect on lower respiratory tract and shows as pneumonia. Although laborious worldwide lockdown and quarantine efforts, the occurrence of COVID-19 continues to increase. Proper and well-designed strategies are needed to reduce social and economic consequences arisen due to this pandemic disease. Presently, there is no effective specific vaccine and anti-viral drug supported by great-level confirmation, but dexamethasone is approved in UK for treatment of critically ill COVID-19 patients (patients on ventilators and patients requiring only oxygen) on June 16, 2020. Further research is required to clarify the factors that affect virus pathogenesis and lethal infections.


Author(s):  
Kamla Pathak ◽  
Devender Pathak ◽  
Ramakant Yadav ◽  
Raj Kumar

Corona viruses are a large family of viruses that cause illness ranging from the common cold to more severe diseases. A novel coronavirus (nCoV) is a new strain that has not been previously identified in humans. On 30 January 2020, the WHO Director-General declared the novel corona virus (COVID-19) outbreak a public health emergency of international concern. Many fatalities have occurred and continue to happen. Despite staggering research efforts for therapeutics, complete cure is still a distant dream. The write up updates the treatment approaches utilized in clinical settings across the globe and the clinical trials registered in the Federal register and WHO register for drugs and vaccines to combat the pandemic.


2021 ◽  
Vol 71 ◽  
pp. 484-485
Author(s):  
Matthew R. Smeds ◽  
Faisal Aziz ◽  
Jonathan Bath

PMLA ◽  
1966 ◽  
Vol 81 (5) ◽  
pp. 381-388
Author(s):  
William Park

But the Discovery [of when to laugh and when to cry] was reserved for this Age, and there are two Authors now living in this Metropolis, who have found out the Art, and both brother Biographers, the one of Tom Jones, and the other of Clarissa.author of Charlotte SummersRather than discuss the differences which separate Fielding and Richardson, I propose to survey the common ground which they share with each other and with other novelists of the 1740's and 50's. In other words I am suggesting that these two masters, their contemporaries, and followers have made use of the same materials and that as a result the English novels of the mid-eighteenth century may be regarded as a distinct historic version of a general type of literature. Most readers, it seems to me, do not make this distinction. They either think that the novel is always the same, or they believe that one particular group of novels, such as those written in the early twentieth century, is the form itself. In my opinion, however, we should think of the novel as we do of the drama. No one kind of drama, such as Elizabethan comedy or Restoration comedy, is the drama itself; instead, each is a particular manifestation of the general type. Each kind bears some relationship to the others, but at the same time each has its own identity, which we usually call its conventions. By conventions I mean not only stock characters, situations, and themes, but also notions and assumptions about the novel, human nature, society, and the cosmos itself. If we compare one kind of novel to another without first considering the conventions of each, we are likely to make the same mistake that Thomas Rymer did when he blamed Shakespeare for not conforming to the canons of classical French drama.


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