Bacteriology and Outcome of Neonatal Septicaemia: Experience from a Mission Hospital in Nigeria

2021 ◽  
Author(s):  
Martynas Jakulis

In 1695, Jan Teofil Plater and his wife Aleksandra founded a hospital for six impoverished nobles in Vilnius. Situated near the newly built church of the Ascension and the convent of the Congregation of Mission in the Subocz suburb beyond the city walls, this hospital was the first and, until the end of the eighteenth century, the only charitable institution providing care for individuals of particular social status. The article, based on the hospital’s registry book and other sources, examines the quantitative, as well as qualitative characteristics of the institution’s clientele, such as its fluctuations in size, its social composition, and the causes of its inmates’ impoverishment. The research revealed that, despite the demand for care, the overseers managed to maintain a stable number of inmates, rarely admitting more than one or two persons every year, and thus ensuring a steady operation of the hospital (see table 1). However, in contrast with other charitable institutions in Vilnius, the clientele of the Congregation of Mission hospital changed frequently because of expulsions (39.6 percent of all cases) and inmates leaving the hospital on their own initiative (20.1 percent) already in the first year of their stay. The mortality of inmates (27.8 percent) affected the size and turnover of the clientele to a much lesser extent than observed in other hospitals. Although there are no reliable data on the inmates’ age and health, such statistics show that they probably were younger and healthier than the clients of other charitable institutions in Vilnius. Moreover, the Congregation of Mission hospital’s inmates differed from the clients of other institutions in respect of social composition. Impoverished petty nobles, originating mainly from the districts of Lida and Oszmiana, constituted the majority (56.25 percent) of the hospital’s inmates whose social status is noted in the registry book (62.5 percent). The nobles became clients of the Congregation of Mission hospital either because of old age, disability, as well as other accidental causes, or because of increased social vulnerability outside mutual aid networks, comprised of family members, kin or neighbours. The article argues that the foundation of a hospital designated to provide care primarily for impoverished nobles shows that the poverty of nobles was recognized by contemporaries as a social problem that should be tackled. Keywords: poverty, charity, hospital, the Congregation of Mission, Vilnius, nobles, eighteenth century.


2019 ◽  
Author(s):  
Lloyd Sampa

BACKGROUND Anemia is a worldwide major problem known to affect people throughout the world. It has an adverse effect on both the social and economic development. The worldwide prevalence of anemia is 9% in developed nations. The global estimate indicates that 293.1 million of children under five years, approximately 43%, are anaemic worldwide and 28.5% of these children are found in sub Saharan Africa. In Zambia specifically Kasempa, no documented studies on prevalence have been done. Despite iron supplementation being given to pregnant women and the availability of blood transfusion. The burden of the disease remains high as determined by high mortality and morbidity. This study aims at determining the prevalence of anemia and the associated risk factors among under-five children at Mukinge Mission Hospital in Kasempa District. Knowledge of prevalence and the associated risk factors of anaemia will enhance early detection and timely management. OBJECTIVE 1.To determine the hemoglobin status of anaemia by its severity among anaemic under-five children admitted at Mukinge Mission Hospital. 2.To assess the association of anaemia with Malaria among under-five children admitted at Mukinge Mission Hospital. METHODS This was a retrospective study review of under-five children that were diagnosed and managed of Anemia at Mukinge Missions Hospital, over the period of period of 2015, 2017 and 2018. .Data of the variables of interest was extracted and analyzed using SPSS. RESULTS A sample population of 52 children was included in our study. The majority of the children were females 28 (53.8 %) and 24 (46.2 %) were Males. It was found that moderate and severe anaemia was 17.3% and 82.7 % respectively. Additionally, Majority of the anaemic children (75%) had Normocytic anaemia. The Pearson Chi square test revealed no statistical relationship between the variables; Malaria (p=0.58), Age (P=0.82), Gender (P=0.91). CONCLUSIONS According to our study, 39 (75%) had normal mean corpuscular volume which could suggest chronic diseases and sickle cell anemia. 11 (21.2%) had a low mean corpuscular volume indicating Microcytic anemia which could suggest diseases such as iron deficiency and thalassemia among many other causes. However, we were unable to determine the specific cause of anemia.


2018 ◽  
Vol 3 (1) ◽  
pp. 86-93
Author(s):  
Dharma Prasad Khanal

The historical event of the development of pharmacy was started during ancient Lichchhavi ruler Amshu Berma date back to 605-620 AD when a Ayurvedic hospital was established. In 1641-1674 AD, King Pratap Malla started ayurvedic medicine production unit in the royal place. Modern allopathic medicines were introduced in Nepal in 1816 AD after Suguali Treaty and establishment of British residency in Nepal. Allopathic medicine manufacturing was started in 1969 in private sector and a government undertaking Royal Drug Limited was established in 1972.  Department of Drug Administration (DDA), a drug regulating Agency of the country was established according to the Drug Act in 1979. The pharmaceutical education was started in Nepal with the commencement of the Proficiency Certificate Level, a two and half year program (Intermediate in Pharmacy that is similar to Diploma of Pharmacy) at the Institute of Medicine, Tribhuban University in 1972. Santabhavan Hospital (present patan Hospital that was established in 1956) is pioneer to start hospital Pharmacy service in Nepal followed by Tansen Mission hospital Palpa that was started operation in 1959.Journal of Manmohan Memorial Institute of Health SciencesVol. 3, No. 1, 2017, page: 86-93 


Apmis ◽  
1999 ◽  
Vol 107 (1-6) ◽  
pp. 593-600 ◽  
Author(s):  
A. RØNNESTAD ◽  
T. G. ABRAHAMSEN ◽  
P. GAUSTAD ◽  
P. H. FINNE

2003 ◽  
Vol 52 (9) ◽  
pp. 835-837 ◽  
Author(s):  
Mehmet Yalaz ◽  
Suleyha Hilmioglu ◽  
Dilek Metin ◽  
Mete Akisu ◽  
Deniz Nart ◽  
...  

BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e017665 ◽  
Author(s):  
Charles Ampong Adjei ◽  
Florence Naab ◽  
Ernestina S Donkor

ObjectiveThis study explored the experiences of people with hepatitis B in the Accra metropolis.DesignThe study employed qualitative exploratory descriptive design with purposive sampling technique. Data were collected through face-to-face interview and transcribed verbatim. The data were analysed using content analysis.SettingsParticipants were recruited from one government and one mission hospital in Ghana.ParticipantsFourteen individuals aged between 26 and 45 years with hepatitis B infection were interviewed.ResultsThe findings of the study showed that people with hepatitis B in the Accra metropolis were unclear about the impact of their infection. Furthermore, they experienced psychological and social problems especially when they were initially informed about their hepatitis B status. Sadness, fear, shock, shame and disbelief were some of the experiences reported by participants. Coping strategies adopted include religiosity, denial and lifestyle modification.ConclusionsIt is, therefore, necessary as a country to integrate hepatitis B counselling into the already existing HIV structures in the health delivery system to offer support for individuals diagnosed with hepatitis B. Furthermore, it is important to draw lessons from the process used in the diagnosis of HIV, particularly in ensuring that people provide consent for being tested.


2021 ◽  
Vol 8 (14) ◽  
pp. 854-860
Author(s):  
Nandita Pal ◽  
Sanat Kumar Dolui ◽  
Bhuban Majhi ◽  
Manisha Das

BACKGROUND Septicaemia is a leading cause of morbidity and mortality in neonates. Antimicrobial prescription for neonatal septicaemia (NS) should be wisely used depending on the regional spectra of infecting microbes and their antimicrobial resistance (AMR) patterns which vary over time, place and host factors. METHODS This was a descriptive cross-sectional study conducted from January 2017 to June 2017 among 102 cases of NS admitted in neonatal intensive care units (NICU). Demographic data of the concerned neonates was collected through a predesigned checklist. Blood collected from neonates was processed for culture and sepsis screen. Antimicrobial susceptibility testing was performed for the cultured isolates and phenotypic AMR patterns were observed. RESULTS Most of the studied neonates had subnormal birth weight (86). Blood culture showed predominance of gram-negative bacilli (GNB) among which Klebsiella pneumoniae was the most common followed by Burkholderia cepacia complex. Coagulase negative staphylococcus species (CoNS) was most numerous among the cultured gram-positive cocci (GPC). Candidemia of late onset was confirmed in 25 neonates. Early onset sepsis was predominantly caused by GNB (29 / 31) predominated by Klebsiella pneumoniae. Multi drug resistant (MDR) pathogens viz., extended spectrum beta-lactamase (ESBL) producing GNB, carbapenem resistant-GNB (CR-GNB) and methicillin resistant staphylococcus (MRS) phenotypes were notably prevalent. CONCLUSIONS Multidrug resistant microorganisms are notably prevalent in neonatal septicaemia. In clinically suspected very sick septicaemic neonates not showing much improvement with guideline-led empirical antimicrobial therapy, an early antibiogram guided change over to meropenem and amikacin or even to colistin in case of reported carbapenem resistance, is highly recommended. KEYWORDS Antimicrobial Resistance, Blood Culture, Multi Drug Resistance, Neonatal Septicaemia


2016 ◽  
Vol 17 (2) ◽  
pp. 110
Author(s):  
S Pius ◽  
M Bello ◽  
Y Mava ◽  
BA Ibrahim ◽  
AG Faruk ◽  
...  

1989 ◽  
Vol 19 (1) ◽  
pp. 21-24 ◽  
Author(s):  
R N Villar ◽  
V K Solomon ◽  
J Rangam

The pattern of knee pathology seen in an Indian mission hospital following the introduction of knee clinics is described. This paper reports the results of the first 200 consecutive patients seen at these clinics, relating the findings to anticipated treatments. The occurrence of degenerative disease was high. The importance of knee flexion, in order to be able to squat, is highlighted. The necessity to adopt this position materially alters the types of treatment that can be offered to this group of people. It is concluded that treatments common to the West are not always suitable for patients in the Third World.


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