scholarly journals Evaluation of Antifungal Activity of Methacrylic Acid incorporated in Conventional Heat-activated Resins

2017 ◽  
Vol 8 (2) ◽  
pp. 129-133
Author(s):  
Lokendra Gupta ◽  
IN Aparna ◽  
B Dhanasekar ◽  
Sujatha Bhat ◽  
Priyanka Agarwal

ABSTRACT Aim The aim of this study was to evaluate the antifungal activity of heat-activated denture base resins modified with different concentrations of methacrylic acid (MAA). Materials and methods Methyl methacrylate (MMA) monomer of heat-activated resins was modified with different concentrations of MAA (0, 15, 20, and 25%) for the preparation of specimens to evaluate antifungal activity of heat-activated resins. Prepared specimens were stored in distilled water at 37°C for 1 day and 1 week before the evaluation of microbial adhesion. Microbial adhesion of Candida albicans cells to acrylic samples was examined under light microscopy after Gram staining of all the acrylic samples. Data were subjected to one-way analysis of variance followed by post-hoc Tukey's honest significant difference test. A value of p < 0.05 was considered to be statistically significant Results Addition of MAA to the MMA monomer was found to significantly reduce the adhesion of C. albicans for all the groups. Reduction of C. albicans cell adherence was found significant for all three groups (I, II, and III) as compared to control, both at 1 day (p < 0.001) and 1 week (p < 0.001) after storage in distilled water Conclusion Addition of MAA to conventional denture base formulations reduced the adhesion of C. albicans. This method of incorporating antifungal property to denture base resins can effectively be used to reduce denture stomatitis in elderly and immunocompromised patients. How to cite this article Gupta L, Aparna IN, Dhanasekar B, Bhat S, Ginjupalli K, Agarwal P. Evaluation of Antifungal Activity of Methacrylic Acid incorporated in Conventional Heat-activated Resins. World J Dent 2017;8(2):129-133.

Author(s):  
Kubra Degirmenci ◽  
Mustafa Hayati Atala ◽  
Canan Sabak

Avoiding biofilm formation on dentures is associated with maintaining the surface properties of acrylic-based dentures. The aim of the study is to investigate the effects of two different cleaning agents (Corega and Klorhex 0.2% chlorhexidine gluconate) on surface roughness of the denture regarding efficacy of curing procedures. A total of sixty disc-shaped specimens were prepared with two different methods as long and short curing processes. The specimens were divided into subgroups according to the immersion solutions (distilled water, Corega tablet group and Klorhex 0.2% chlorhexidine gluconate group) (n=10). The samples were kept in a solution for 8 hours per day during a month. The average Ra1 (before exposure to the cleanser agent) and Ra2 (after exposure to the cleanser agent) of each sample was measured. A two-way ANOVA and post hoc Tukey test was used for statistical analysis. The solutions significantly increased the Ra values in both acrylic groups (p<0.001). While the effect of the distilled water group was significantly lower than Corega and Klorhex in the long-term curing group (p<0.05), no significant difference was found in the short-term curing group (p>0.05). The long-term curing time is highly effective in decreasing the surface roughness of the acrylic base material.


2021 ◽  
Vol 17 (1) ◽  
pp. 22-26
Author(s):  
Kadek Ayu Wirayuni ◽  
◽  
I Made Hendri Dwi Saputra ◽  

Introduction: The denture base is the part of the removable denture that is supported by good adaptation to the underlying oral tissue. Most of the denture bases are made of acrylic or polymethyl methacrylate resin, better known as PMMA. However, the acrylic resin also has disadvantages such as easily broken and absorbs liquids both water and chemicals. The chemical absorption like alcohol, ethanol, and some drinks that contain acidic materials will chemically be induced with acrylic resin and settle in the pores of the acrylic resin. The chemical damage or defect creates roughness on the surface of the acrylic resin which can cause cracking or crazing and a decrease in surface strength and hardness. Materials and Methods: The method used in this research was a laboratory experimental design with a post-test-only control group using 12 samples consisting of 2 different types of samples by measuring the surface roughness of the acrylic resin after immersing the sample with a predetermined time. Results and Discussions: One-way ANOVA test results showed a significant difference in surface roughness after the samples immersion with a value of p = 0.006 (p <0.05). Conclusions: Based on this research, can be concluded that there is an increase in the surface roughness of the heated polymerized acrylic resin for 3 hours and 4 hours of immersion. The longer the heated polymerized acrylic resin is soaked in arak hence the level of surface roughness increases.


2021 ◽  
Vol 6 (2) ◽  
pp. 71
Author(s):  
Rudy S ◽  
Titik Ismiyati ◽  
Endang Wahyuningtyas

Heat cured acrylic resin is the most commonly used denture base materials.  Zirconium dioxide (ZrO2) nanoparticles can be applied as additional filler to increase mechanical strength and to reduce the amount of residual monomer. The aim of this research is to analyze the effect of ZrO2 nanoparticles concentrations as filler on heat cured acrylic resin denture base toward viability of fibroblast cells. Twenty four disc-shaped heat cured acrylic resin plate (diameter 5 mm; width 2 mm), were divided into 4 groups (n=6), they were consisted of group I control (acrylic resin), group II acrylic resin with 2.5% ZrO2, group III acrylic resin with 5% ZrO2, and group IV acrylic resin with 7.5% ZrO2. Cell viability was obtained using MTT assay and ELISA plate reader. The result is examined with one way ANOVA followed by LSD post hoc assessment. The result showed highest cell viability percentage on experimental group of 2.5% ZrO2 with value as high as 97.49%. One way ANOVA test and LSD post hoc test showed a significant difference between groups (p<0.05). The conclusion of this research is ZrO2 nanoparticles concentration utilized as filler on heat cured acrylic resin denture base is effect to viability of fibroblast cells, and ZrO2 nanoparticles 2.5% shows the highest viability of fibroblast cell compared to 5% and 7.5% ZrO2 nanoparticles concentrations  


2013 ◽  
Vol 24 (4) ◽  
pp. 357-361 ◽  
Author(s):  
Newton Sesma ◽  
Alessandra Lima Rocha ◽  
Dalva Cruz Lagana ◽  
Bruno Costa ◽  
Susana Morimoto

Complete dentures acts as a reservoir for microbial colonization, which may lead to systemic infections. Microwave irradiation has been used as an efficient method of denture disinfection. Even though current methods eliminate denture-base microorganisms, a recurrence rate of denture stomatitis (DS) is still observed among denture-wearing patients. It was hypothesized that microwave disinfection kills microorganisms but do not remove dead bacteria from the denture surface. To test this hypothesis, the biofilm found in the dentures of 10 patients with DS was evaluated. In addition, the effects of microwave irradiation plus brushing (MW+B) on the denture biofilm and the combination of denture cleanser with microwave irradiation and brushing (MW+DC+B) for the removal of denture-accumulating microorganisms were investigated. Microbiological data were analyzed statistically by nonparametric analysis (Friedman/Wilcoxon, α=0.05). MW+B and MW+DC+B were effective in reducing the rate of microorganisms (99.2% and 99.5% respectively), but without significant difference between them (p=0.553). However, it was observed that the complete removal of microorganisms from denture surface was only possible when all regimens were combined (MW+DC+B). Microwave irradiation in combination with soaking in denture cleanser and brushing effectively disinfected the dentures and removed denture biofilm.


2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Mohammed Gad ◽  
Aws S. ArRejaie ◽  
Mohamed Saber Abdel-Halim ◽  
Ahmed Rahoma

Objective.The aim of this study was to evaluate the effect of incorporation of glass fiber, zirconia, and nano-zirconia on the transverse strength of repaired denture base.Materials and Methods.Eighty specimens of heat polymerized acrylic resin were prepared and randomly divided into eight groups (n=10): one intact group (control) and seven repaired groups. One group was repaired with autopolymerized resin while the other six groups were repaired using autopolymerized resin reinforced with 2 wt% or 5 wt% glass fiber, zirconia, or nano-zirconia particles. A three-point bending test was used to measure the transverse strength. The results were analyzed using SPSS and repeated measure ANOVA and post hoc least significance (LSD) test (P≤0.05).Results.Among repaired groups it was found that autopolymerized resin reinforced with 2 or 5 wt% nano-zirconia showed the highest transverse strength (P≤0.05). Repairs with autopolymerized acrylic resin reinforced with 5 wt% zirconia showed the lowest transverse strength value. There was no significant difference between the groups repaired with repair resin without reinforcement, 2 wt% zirconia, and glass fiber reinforced resin.Conclusion.Reinforcing of repair material with nano-zirconia may significantly improve the transverse strength of some fractured denture base polymers.


2019 ◽  
Vol 7 (5) ◽  
pp. 862-868
Author(s):  
Eman Mostafa Ahmed Ibraheem ◽  
Hoda Gaafar Hassan Hammad

BACKGROUND: Various clinical cases of thermopress denture base materials necessitate the use of denture adhesives to achieve proper retention and stability of the removable prosthesis. Therefore; the microhardness of these flexible materials as surface property and its’ alterations due to the application of various denture adhesives are still crucial issues to be discussed. AIM: This study aimed to investigate the impact of two commercially available denture adhesives (DAs) on microhardness of a flexible denture base material. METHODS: A total of 30 duplicate disc specimens (DS) were fabricated from a thermoplastic injection moulded resin (TR). The obtained 30-disc specimens (DS) were stored in distilled water for seven days, and then their microhardness was measured using Knoop Hardness Test (KHN) under a 10 g load for 10 seconds. The denture adhesives were prepared, and 15 DS were immersed in Corega Super Cream, while the other 15 DS were soaked in Fitty Dent Cream. All DS were stored in distilled water at 37°C. After 30 days of immersion in DAs, microhardness of DS was again measured. T-test for paired observation was used to investigate any alterations in microhardness between the baseline and after 30 days of immersion in the DAs. Statistical analysis was performed with SPSS 20®, Graph Pad Prism® and Microsoft Excel 2016 with a significant level set at P ≤ 0.05. RESULTS: Student`s t-test had revealed a significant difference between both groups after application of denture adhesive as a P value < 0.05. The obtained results showed that DA material type, flexible denture base material and their surface interaction provoke a statistically significant outcome on the mean microhardness. CONCLUSIONS: DAs were found to affect the microhardness of thermoplastic injection moulded resin (TR); which may jeopardise the durability and serviceability of complete denture and patients’ acceptance and comfortability.


Author(s):  
Ayşe Tuğba Ertürk-Avunduk ◽  
Seçkin Aksu ◽  
Ebru Delikan

Objective: This study investigated the effects of three types of mouthwash on the color stability of three resin-based restorative materials (nanohybrid resin composite, sonic-activated bulk-fill material, and compomer). Materials and Methods: To this end, 120 cylindrical disc specimens were prepared and polished, after which they were incubated in distilled water for 24 hours for post-polymerization. The baseline color values of each specimen were measured with a spectrophotometer, then the specimens were randomly divided into four groups. Following immersion in the mouthwashes for 24 hours, the specimens were rinsed with distilled water and dried before the color measurement was repeated. The values of color change (∆E₀₀) were subsequently calculated. A two-way analysis of variance and Duncan’s post hoc multiple comparison tests were conducted to determine statistically significant differences among the restorative materials. Results: All samples showed discoloration after immersion, albeit some instances of discoloration were imperceptible. In this respect, a statistically significant difference was found among the restorative materials and mouthwashes (p<0.05). Imperceptible ∆E₀₀ values were derived on the nanohybrid resin composite and compomer, but perceptible and acceptable ∆E₀₀ values were detected on the sonic-activated bulk-fill materials (p<0.05). The clinically unacceptable discoloration was observed on the sonic-activated bulk-fill composite immersed in Listerine®. Conclusions: Clinicians should make recommendations based on the potential staining capacity of mouthwashes prescribed for daily use in restorative materials. In this way, the need for renewal of restorations due to discoloration could be avoided.


2008 ◽  
Vol 19 (1) ◽  
pp. 46-50 ◽  
Author(s):  
Vinicius Humberto Nunes ◽  
Ricardo Gariba Silva ◽  
Edson Alfredo ◽  
Manoel D. Sousa-Neto ◽  
Yara T. C. Silva-Sousa

This study evaluated comparatively the adhesion of Epiphany and AH Plus endodontic sealers to human root dentin treated with 1% NaOCl and 1% NaOCl+17% EDTA, using the push-out test. Sixty root cylinders obtained from maxillary canines had the canals prepared and were randomly assigned to 3 groups (n=20), according to root dentin treatment: GI - distilled water (control), GII - 1% NaOCl and GIII - 1% NaOCl+17% EDTA. Each group was divided into 2 subgroups (n=10) filled with either Epiphany or AH Plus. Bond strength push-out test data (kN) were obtained and analyzed statistically by ANOVA and Tukey's post-hoc test. There was statistically significant difference between sealers (AH Plus: 0.78 ± 0.13; Epiphany: 0.61 ± 0.19; p<0.01) and among root dentin treatments (distilled water: 0.58 ± 0.19; 1% NaOCl: 0.71 ± 0.12; 1% NaOCl+17% EDTA: 0.80 ± 0.17; p<0.05). In conclusion, AH Plus sealer presented greater adhesion to dentin than Epiphany, regardless of the treatment of root canal walls.


2011 ◽  
Vol 10 (3) ◽  
pp. 135
Author(s):  
Rini Defika Putri ◽  
Viona Diansari ◽  
Iin Sundari

The hardness of denture base is influenced with the habit of most commonly consumed. Ulee Kareng Aceh coffeewas atype of robusta coffee which is acidic. The purpose of this study was to determine the change of surfacehardness of acrylic denture base after being immersed in ulee kareng coffee for 3 days. Twelve specimens (5 mmdiameter and 2 mm thickness)were randomly distributed in two groups: control (immersion in distilled water) andexperimental (immersion in Ulee Kareng Aceh coffee). Hardness was measured before and after immersion usingKnoop Microhardness tester (Shimadzu). Data were statistically analyzed by Mann Whitney and Wilcoxon test (α =0.05). The results of the study showed a significant difference between the groups P < 0.05. The surface hardness ofacrylic denture base decreased after immersion for both group P < 0.05.


2018 ◽  
Vol 1 (1) ◽  
Author(s):  
Dwi Tjahyaning Putranti ◽  
Afrina Fadilla

  Introduction: Heat-polymerized acrylic resin is used to manufacture almost all denture bases. One of the disadvantages of acrylic resin is its porosity and surface roughness; food scraps attach easily. If the dentures are not cleaned, they become a place for microbial species development and cause denture stomatitis, with Staphylococcus aureus and Candida albicans as the major etiologic agents. Adding nanoparticles of titanium dioxide to heat-polymerized acrylic resin may provide antimicrobial activity to the acrylic resin base.   Objectives: This study aimed to determine whether adding TiO2 nanoparticles to heat-polymerized acrylic resin denture base materials affected the amounts of Staphylococcus aureus and Candida albicans.   Methods: The samples in this study used heat-polymerized acrylic resin without the addition of TiO2 nanoparticles and with the addition of 2%, 3%, and 4% TiO2 nanoparticles on test bar sizes of 10 mm × 10 mm × 1 mm. There were 48 total test samples: 24 of Staphylococcus aureus and 24 of Candida albicans. The obtained data were analyzed by a one-way ANOVA test.   Results: The results showed that adding TiO2 nanoparticles influenced the amount of Staphylococcus aureus (p<0.05) and Candida albicans (p<0.05). A least significant difference test showed differences of effect in the amounts of Staphylococcus aureus when TiO2 concentrations of 2%, 3%, and 4% were added to heat-polymerized acrylic resin denture base and there were differences in effect to amounts of Candida albicans when TiO2 concentrations of 2%, 3%, and 4% were added to heat-polymerized acrylic resin denture base.   Conclusion: Adding TiO2 nanoparticles to heat-polymerized acrylic resin denture base material affects the amounts of Staphylococcus aureus and Candida albicans.


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