scholarly journals The 2005 Lancet review proved superior quality of homeopathy trials: what's next?

2021 ◽  
Vol 8 (28) ◽  
pp. 110-118
Author(s):  
Lex Rutten

Several former reviews showed positive effects of homeopathy, but in 2005 The Lancet published a review which claimed that homeopathy is a placebo effect. This review was criticised for not revealing essential information. A reconstruction of post-publication data challenges the negative conclusion. The only conclusion that was rectified by the methodology of the 2005 review was that the quality of homeopathy trials, and especially of smaller trials, is better than quality of conventional trials. The comparison of the effect of 110 homeopathy trials with 110 matched conventional trials was flawed by selection bias, different publication bias, different quality, and different safety. Nevertheless, there is no significant difference of effects between both methods. Discussions about proof for homeopathy are in fact discussions about science. The prior assumption that homeopathy cannot work pervades all aspects of this discussion and is not properly evaluated in the introduction of most analyses.

Author(s):  
Mohammad Hassan Dashty Khavidaki ◽  
Mahmood Kamali Zarch ◽  
Naser Mohammadi Ahmadabadi ◽  
Haider Hosseini

Introduction: Numerous important factors such as physical and mental condition affect the quality of life Job stress is one of the key factors in decreasing productivity in organizations. Given the positive effects of physical activity on quality of life, this study aimed to compare the quality of life between active and inactive workers (case study). Methods: This study was a cross-sectional comparative study.190 tile and cement-manufacturing workers who were eligible for the study were selected completely voluntarily, based on a convenience sampling. Of these, according to Beck questionnaire, 88 were selected in inactive and 64 in active groups; Weir and Sherborn questionnaire was used for assessing the quality of life (SF-36). For analysis the data, independent T-test and SPSS 23 software were used for analysis (P≤0.05). Results: The results showed that physical, psychological and quality of life components in the active group of cement factory workers were (p = 0.012) (p = 0.001) (p = 0.005) and tile workers (p = 0.012) (P = 0.005) (p = 0.014) was a significant and more compare to the inactive group, but there was no significant difference between active and inactive workers of the two tile and cement factories. Conclusion: The results of this study showed the positive role of exercise and physical activity on the quality of life of people working in cement and tile factories. It seems easier physical activity and sports are related to the quality of life of workers and have nothing to do with the workplace.  


2020 ◽  
Vol 4 (1) ◽  
pp. 59-67
Author(s):  
Eka Swarnadi Luh ◽  
Ketut Budi Susrusa ◽  
Ida Ayu Listia Dewi

LPDs are non-bank financial institutions that are regulated and approved by the Regional Regulations of the Province of Bali. The management of LPD is fully handed over to the relevant Pakraman village. In line with the rapid development of LPDs, it turns out that on the other hand it shows diverse performance, so that LPDs need to pay attention to the level of product quality and customer interest in the products offered.            The purpose of the study was to determine the comparison of product quality and interest in saving at the Tajun Traditional Village LPD with the Traditional Village of Tegal. The number of samples from Tajun Adat Village LPD was 98 people and the LPD of Tegal Traditional Village was 84 people. The research data were analyzed by the Mann-Whitney Test. The results showed that there was a significant difference between the quality of the products of the Adat Village of Tajun LPD and the Traditional Village of Tegal. This difference is indicated by indicators of physical evidence, reliability, responsiveness and empathy. The product quality of Tajun Adat Village's LPD is better than the traditional village of Tegal. There is a significant difference between the interest in saving the traditional village of Tajun LPD and the traditional village of Tegal. The difference is in the indicator of confidence. Interest in Saving Tajun Indigenous Village LPD is higher than the Traditional Village of Tegal.


2020 ◽  
pp. 089198872091552
Author(s):  
Marcela Moreira Lima Nogueira ◽  
Jose Pedro Simões Neto ◽  
Marcia Cristina Nascimento Dourado

The quality of life (QoL) of people with Alzheimer disease (PwAD) may be influenced by the type of relationship between carer and the PwAD. Dyads of 98 PwAD/carers (N = 49 spouse-carers; N = 49 nonspouses carers) were measured about QoL, cognition, dementia severity, awareness of disease, functionality, depression, anxiety, and burden of care. Univariate and multivariate regression analyses were conducted to identify the factors that influenced the spouse and nonspouse self-report PwAD QoL (PQOL) and to compare carers’ ratings of PwAD QoL (C-PQOL). The total score of QoL for spouse and nonspouse PwAD showed no significant difference ( P = .29). The linear regression demonstrated that higher awareness of disease was significantly related to spouse PQOL ( P = .001). Nonspouse PQOL was negatively related to lower depression ( P = .007). The total score of QoL for spouse and nonspouse C-PQOL showed no significant difference ( P = .14). The linear regression demonstrated that depression of spouse-PwAD ( P < .001) and burden of care ( P = .001) were negatively related to spouse-dyads’ C-PQOL. The nonspouse-dyads C-PQOL was negatively related to depression of nonspouse-PwAD ( P < .001), awareness of disease ( P = .001), and the mood of the carer ( P = .01). Spouse and nonspouse PwAD evaluate PQOL better than carers (C-PQOL). No significant difference was found in the total PQOL and C-PQOL of spouse and nonspouse, but dyads evaluated differently about what is important to assess QoL.


2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Jin Li ◽  
Sihua Li

Under two situations of static empty gun preview and simulated competition, the validity of self-suggestion language “preloading compaction,” which suggests attentional withdrawal, was verified, respectively. Methods. The experiments in the two parts were designed in a single factor group. The participants (Chinese disabled biathletes) fired 20 times (4 groups in total, 5 times in each group) both in pretest and posttest, and they used self-suggestion before each group of firing in posttest. Optoelectronic shooting device based on wireless laser transceiver technology was selected to collect the shooting technical indicators, scores, and other information. The operation evaluation form reflected the subjective feelings of the participants, and the heart rate was measured by the chest band. Results. By the method of big data analysis, under the condition of static empty gun preview, the results showed that there was an extremely significant difference between shooting score and quality of triggering. All the marks on the operation evaluation form improved after the intervention. In the mock competition situation, shooting score has highly significant differences with quality of triggering and relative triggering value and significant difference with aiming ability. The marks of the operation evaluation form have been improved; the heart rate of firing all decreased in different degrees. Conclusions. The attentional withdrawal has positive effects on the shooting scores, technical indicators of optoelectronic shooting device, subjective feelings, and heart rate of disabled biathletes under the two conditions. TIRE (the timing of firing) is the most sensitive indicator and can be used as the focus of future training and scientific research.


2018 ◽  
Vol 36 (4) ◽  
pp. 630-643
Author(s):  
Janice N Killian ◽  
Lawrence Branco Sekalegga

To examine the quality of rhythmic improvisations after learning Ugandan folksongs via notated or aural/oral means, we asked university music majors ( N = 32) to practice two Ugandan folksongs via Western notation or while viewing a prerecorded video of an expert Ugandan performer singing the same song to mimic aural/oral tradition conditions. Subsequently participants heard an authentic performance of the song they had just learned and were asked to create a rhythmic accompaniment to that song. All conditions were counterbalanced by treatment and by song. Resulting improvisations were judged regarding whether the first was better than the second. Results indicated no significant difference between improvisations on the basis of how the song was learned ( p = 0.2617), differences between the songs themselves ( p = 0.1261) or the order of the songs ( p = 0.7518). Participants improvised better when the song was learned under notation conditions (differences not significant), but 70.1% of participants preferred to learn the song via aural/oral means ( p = 0.0041). Results are discussed in terms of challenges in assessment of improvisations and pedagogical implications for future research.


2014 ◽  
Vol 37 (2) ◽  
pp. 121-128 ◽  
Author(s):  
Martin Nikolovski ◽  
Ljupco Mickov ◽  
Monika Dovenska ◽  
Vladimir Petkov ◽  
Branko Atanasov ◽  
...  

Abstract Motility patterns of spermatozoa are an indicator of their fertilizing capacity. Reduced glutathione (GSH) has been reported to induce positive effects on the biological quality of the frozen-thawed spermatozoa. The aim of this study was to investigate the effects of GSH addition to semen extender based on the following kinetic parameters: continuous line velocity (VSL), average path velocity (VAP), curvilinear velocity (VCL), amplitude of lateral head displacement (ALH), linearity (LIN), straightness (STR), beat cross frequency (BCF), total motility (tMOT) and progressive motility (pMOT), and to appoint them as indicators of its presence. A soybean-based extender was used for dilution of the semen samples, fractioned in two parts, one containing GSH (5 mMol/ml) and second without GSH. The ejaculates (n=48) were collected from two rams (January - May, 2013) which were classified in two groups according to the used extender: Group 1 (with GSH, n=24) and Group 2 (without GSH, n=24), and then frozen in liquid nitrogen on -196°C degrees in a programmable freezer. Assessment of the samples has been performed post-thawing (30 sec. at 37°C) on CASA equipment, acquiring kinetic parameters. Results showed that only VSL and BCF have a statistically significant difference between group1 and group 2 (102.98±15.13 vs. 88.47±20.63, t=2.77, p<0.01 and 32.01±2.68 vs. 89.47±2.92, t=3.13, p<0.01, respectively). The summary of the investigation concludes that none of the kinetic parameters could be appointed as indicators that confer the positive effect of GSH as an additive to soy-bean semen extender.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Bomi Ahn ◽  
Yoo-Sook Joung ◽  
Jeong-Yi Kwon ◽  
Dong Ik Lee ◽  
Soohwan Oh ◽  
...  

Abstract Background Attention problems and decreased quality of life are frequently accompanied in Cerebral Palsy (CP), which can negatively affect rehabilitation of physical disability. However, the majority of affected children remain untreated in the aspects of attention or psychosocial factors. Equine-Assisted Activities and Therapies (EAAT) use horse as a therapeutic modality including grooming as well as mounted riding activities in which patients exercise and experience mounted stimulation. It is known to help improve attention in children with ADHD, so that it can be an exercise therapy that is expected to improvement of attention as well as rehabilitating effects in CP patients. EAA may be a promising strategy to address the unmet need for CP patients. This study aims to investigate the efficacy of EAA for children with CP, those with both CP and ADHD and confirm the comorbidity between CP and ADHD. Methods Forty-six children with cerebral palsy participated in this study. For the exercise group, they participated in a 40-min session twice a week for a 16-week period, while the control group engaged in daily life without any special treatments. Each children individually were assessed on attention and psychological wellbeing at baseline and post-treatment. Comorbidity were identified based on the Diagnostic and Statistical Manual of Mental Disorder 5th edition (DSM-5) and confirmed by Korean Kiddie-Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version (K-SADS-PL). Results Perseveration rated using the Conner’s Performance Test (CPT) showed a significant decrease only in the exercise group (p < .024). However, no significant improvement in children’s quality of life was observed after EAA program compared with control group. Among the total participants, fifteen children (31.91%) were diagnosed with ADHD. When conducting an additional analysis with the subsample of CP patients diagnosed with ADHD, the d’, commission error and perseveration showed a significant decrease only in the exercise group. Children with CP and ADHD reported an improvement in quality of life both in exercise and control group, but only in the exercise group social functioning exhibited a significant difference. Conclusion The positive effects of the EAA on attention and quality of life were confirmed. Children with CP in the exercise group were more capable to sustain their attention longer. Those with CP and ADHD showed an increase in attention and perceived to have better social skills after receiving 16 weeks of EAA compared to those in the control group. Considering high comorbidity of CP and ADHD, it seems that the EAA program could be the better alternative treatment for CP with attentional problem. The results of this study will contribute to growing evidence for the efficacy of EAA in children especially with CP and ADHD. Trial registration This trial was registered on ClinicalTrials.gov (NCT03870893). Registered 26 July 2017.


2021 ◽  
Author(s):  
Sheng Guo ◽  
Changming Xiao ◽  
Chenglong Wang ◽  
Sen Li

Abstract Background: The prior objective of this study is to discuss individualized puncture path of percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) in the treatment of the elderly with severe osteoporotic vertebral compression fractures (OVCFs).Previous studys have compared the clinical efficacy and safety of PVP and PKP. Based on their research results, we will make a further investigation about this two main operations in treating OVCFs and propose a set of original and feasible puncture plan in clinical work, which will improve efficiency and safety of PKP and PVP.Methods: We searched all the articles related to PVP and PKP in treating OVCFs on medicine database. Issues of the selected journals published from 1999 to 2020 were hand-searched by us, including experimental or review articles. Combining conclusions of these researches and clinical cases of our department, we are forged to find more common and preferred treatments for patients with OVCFs under different situations.Results: Most of thees studies revealed that there was no significant difference in relieving the back pain and improving the quality of patients’ life between PVP and PKP surgeries, which generally based on the VAS scores and Oswestry disability index(ODI) scores. However, PKP has a lower rate of bone cement leakage and incidence of adjacent vertebrae fracture than the PVP. Restoring the vertebral height and local kyphotic angle corrections of PKP are much better than that of PVP. On the other hand, more operation time, higher cost and rate of re-surgery of PKP should also be taken into consideration when we make better choice for patients. Therefore, we are forged to find individual methods for patients who are diagnosed as OVCFs.Conclusions: Both the two types of operation can significantly relieve the pain of the patients ,reduce the risk of occurring complication and mortality after OVCFs. There is no so-called best treatment for patients between PVP and PKP. We should take the comprehensive actual conditions into account when choosing surgical methods for patients with OVCFs, which is absolutely vital to us. However, individual puncture path is beneficial for us to make operations including both PKP and PVP.


2014 ◽  
Vol 2 (11_suppl3) ◽  
pp. 2325967114S0017
Author(s):  
Mehtap Kaçmaz Şilil ◽  
Serdar Sargın ◽  
Aziz Atik ◽  
Gökhan Meriç ◽  
Muhammet Özer ◽  
...  

Objectives: Visual sense and proprioception have a big role in motion control. Visual communication ensures the data in proprioceptive period. The other senses of blind people are improved because of the lack of the visual ability but there are not enough data for the proprioceptive quality. The purpose of this study is to compare the knee joint proprioception of the blind and normal sportsmen and figure out the prorioceptive quality. Methods: 16 visually-challenged sportsmen (12 males and 4 females) with an average age 23.6 ±3.1(ranging from 20 to 30), and 16 healthy sportsmen (12 males and 4 females) with an average age 23.5 ±3.5 (ranging from 20 to 29) from the same sport branches were included in the study. Knee joint proprioception of the subjects in the target angle was measured. Angle repeating test was used via digital goniometer which was sensitive to 1 degree. For the statistical analyses of the data Mann-Whitney U, Wilcoxon Signed Ranks tests were used. Results: There were no differences between knee proprioceptions of dominant and non-dominant extremities in both groups. When dominant extremities were compared, blind athletes got less wrong in 15 degrees measurements statistically (p<0.05). All other comparisons revealed no statisticaly significant difference in both groups. Conclusion: It has been determined that the knee joint proprioception of the visually-challenged sportsmen are better than the normal sportsmen. If the normal sportsmen do the training with their eyes closed, the quality of their knee joint proprioception may improve.


2017 ◽  
Vol 11 (1) ◽  
pp. 31
Author(s):  
Mona Iswandari ◽  
Edy Anan

This study aimed to compare the financial performance of The Conventional Rural Bank (BPR) andIslamic Rural Bank (BPRS) in special region Yogyakarta region. The sample is gotten use purposivesampling method is choosing sample that has been fulfill inclusi citeria. Study sample is gotten 70with the case study in special region Yogyakarta region in period 2012-2014. Methods of dataanalysis using Independent Samples T-Test. Test results show that there is no significant differencewhen viewed from the ratio LDR/FDR between BPR and BPRS. Second, there is significant differencewhen viewed from the ratio ROA between BPR and BPRS. Third, there is significant difference whenviewed from the ratio ROE between BPR and BPRS. Fourth, there is significant difference whenviewed from the ratio NPL/NPF between BPR and BPRS. Generally, on the aspec of likuidity,rentibilty, capital ratio and the asset quality of the Conventional Rural Bank (BPR) showed thatfinancial performance is better than the IslamicRural Bank (BPRS).Keywords: Comparison financial performance, the Conventional Rural Bank (BPR), the IslamicRural Bank, Likuidity, Rentibility, Capital Ratio, Asset quality


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