scholarly journals Treatment Motivation in Lung Tuberculosis Patients at Public Health Centres in Denpasar City during COVID-19 Pandemic

2022 ◽  
Vol 9 (1) ◽  
pp. 45-50
Author(s):  
Jonathan Setiawan ◽  
Ida Ayu Alit Widhiartini ◽  
I Gusti Made Aman

Treatment motivation among patients were heavily influenced by duration of therapy and existing side effects. TB supervisors motivated patients in their therapy. Limited communication from TB supervisors due to COVID-19 pandemic risked lowering treatment motivation in TB patients. Objective: get a general description of treatment motivation in TB patients from PHC in Denpasar. Method: descriptive observational with cross-sectional design in March – August 2021 at five PHC in Denpasar area. This study was done online using questionnaire with Google Forms application. Motivation is grouped into low, moderate, and high based on scores from internal factors, external factors, confidence in treatment, and interpersonal help seeking. Results: 86% of patients (43 people) had high treatment motivation, 12% of patients (6 people) have moderate treatment motivation, and two percent of patients (1 people) had low treatment motivation. Summary: Most of TB patients had high treatment motivation (86%). Communication between TB supervisors and patients are highly advised to motivate patients and increase success rate of therapy. Keywords: [Anti tuberculosis drugs, Lung tuberculosis, Treatment motivation].

Author(s):  
Safarianti Safarianti ◽  
Rolan Ronaldo ◽  
Rina Suryani Oktari

Pulmonary Tuberculosis (TB) is a lung infection caused by bacillus bacteria called Mycobacterium tuberculosis. MTB generally attacks the lungs and carries a very high risk of transmission. Patients with TB are potentially non-adherent totake anti-tuberculosis drugs (OAT) regularly as directed due to a long period of medication. Factors affecting ATD taking compliance include knowledge and attitudes of pulmonary TB patients. This study aimed to determine the relationship of knowledge and attitude of tuberculosis patients with compliance of ATD drinking in RSUD dr. Husni Thamrin Natal Regency Mandailing Natal. The research was conducted in dr. Husni Thamrin Natal. This research is an observational analytic by cross sectional design which involved 57 participants taken with consecutive sampling method. Data were processed into Spearman ' s correlation test. The result showed that knowledge (p value = 0,000) and attitude (p value = 0,000) related to OAT drinking compliance. This research had proven that the knowledge and attitudes affected OAT drinking compliance of the TB outpatient in RSUD dr. Husni Thamrin Natal, Mandailing Natal Regency.


Author(s):  
Joko Susanto ◽  
Jusak Nugraha ◽  
Soedarsono Soedarsono

Tuberculosis remains a global health burden. Mycobacterium tuberculosis infection causes humoral and cellularresponses. Macrophages of patients with pulmonary tuberculosis evolve M1 polarization that blocks infection orimmunosuppressive M2, promoting tissue repair mediated by IL-4, IL-10, and IL-13. Previous research showed a decrease ofIL-4R and IL-10 expression in lung macrophages of anti-TB drug resistance. A molecular test can detectrifampicin- resistance. There has been no study, which showed the difference in serum IL-4 levels in rifampicin-sensitive andrifampicin-resistant tuberculosis patients. This study aimed to determine the difference between circulating IL-4 levels inrifampicin-sensitive and rifampicin-resistant pulmonary tuberculosis patients. This cross-sectional observational studyconsecutively recruited subjects based on positive molecular and acid-fast bacilli microscopic examination from MDR-TBClinic of the Dr. Soetomo Hospital between December 2018 to March 2019. Subjects were classified into arifampicin-sensitive and rifampicin-resistant group. On ELISA measurement, IL-4 data were analyzed with SPSS version 17.Mann-Whitney U test and ROC analysis tests were performed, and p < 0.05 was significant for α=0.05 (95% CI). There wassignificant difference between rifampicin-sensitive group (420±281 pg/mL) and rifampicin-resistant group(253±279 pg/mL) (p=0.014). Receiver operating characteristics analysis showed AUC 0.70, the sensitivity of 81.5%, thespecificity of 63.6%, and the cut-off value of 235.6 pg/mL. There was a significantly higher level of circulating IL-4 in therifampicin-sensitive group than the rifampicin-resistant group. IL-4 level in healthy subjects should be measured as thenormal value in the population. Immunology and metabolic parameters should be performed to increase samplehomogeneity. Further study was also needed to understand the IL-4 role in rifampicin resistance of lung tuberculosispatients in the Indonesia population.


2019 ◽  
Vol 1 (2) ◽  
pp. 176-185
Author(s):  
Christine Vita Gloria ◽  
Zulmeliza Rasyid ◽  
Sherly Vermita W ◽  
Elmia Kursani ◽  
Bizanti Umayyah

This study aims to see whether the determinants are related to treatment compliance for pulmonary tuberculosis patients at the 2019 health center. This type of research is a quantitative observational cross-sectional design. The results showed that with a P value of 0.05, there was a significant relationship between knowledge (P value = 0.005 and POR = 14.276), attitudes (P value = 0.506 and POR = 1.615), family support (P value = 0.038 and POR = 1,961), the role of health workers (P values = 0.026 and POR = 4.440), with medication adherence for pulmonary tuberculosis patients. Conclusions, of the 4 variables there are 3 variables related to adherence to taking pulmonary TB drugs in the Work Area of the Siak Hulu II Health Center, namely knowledge, family support, and the role of health workers and 1 unrelated variable, attitude.   Keywords: Obedience, Medicine, Lung Tuberculosis


2013 ◽  
Vol 3 (3) ◽  
Author(s):  
Jahja Teguh Widjaja

AbstrakUntuk dapat bekerja dengan efektif menghadapi M. tuberculosis, sistim imunitas seluler memerlukan kadar IFN-γ dan reseptor IFN-γ di sel-sel mononuklear yang bekerja optimal. Tujuan penelitian ini adalah menganalisis korelasi antara kadar serum IFN-, ekspresi dan fungsi reseptor IFN-γ, dengan kejadian penyakit Tuberkulosis Paru. Observasi analitik dengan rancangan potong silang yang membandingkan kadar serum IFN-γ, fungsi dan ekspresi reseptor IFN-γ, pada pasien TB Paru dengan pasangannya yang sehat, serta menganalisis korelasi antara variabel-variabel tersebut dengan kejadian penyakit TB Paru. Penelitian dilakukan pada Juli 2009 sampai September 2010, di RS Immanuel Bandung dan laboratorium Stem Cell & Cancer Institute, Jakarta. Dibandingkan pasangan hidupnya, kadar serum IFN-γ pasien TB tidak berbeda bermakna, ekspresi reseptor IFN-γ pasien TB lebih tinggi (p=0,041), sedangkan fungsi reseptor IFN-γ pasien TB lebih rendah (p=0,011). Analisis korelasi mendapatkan satusatunya variabel yang mempunyai korelasi bermakna dengan kejadian tuberkulosis paru adalah fungsi reseptor IFN-γ yang rendah (p=0,026, OR 5,56). Pada pasien TB Paru ekspresi reseptor IFN-γ lebih tinggi, tetapi fungsi reseptor IFN-γ lebih rendah dari pasangan hidup sehat. Fungsi reseptor IFN-γ yang rendah ini mempunyai korelasi bermakna dengan kejadian tuberkulosis paru.Kata kunci: tuberkulosis, kadar serum IFN-γ, ekspresi dan fungsi reseptor IFN-γ.AbstractIn order to work effectively against M. tuberculosis, the cell mediated immune system needs serum level of IFN-γ and its receptors in the surface of mononuclear cells to function optimally. The objective of this study is to analyze the correlation of IFNγ serum level, expression and function of IFN-γ receptor, with pulmonary tuberculosis. Analytical descriptive method with cross sectional design that compared the serum level of IFN-γ, function and expression of IFN-γ receptor in pulmonary tuberculosis patients with their healthy spouses, and analyzing the correlation between these variables with pulmonary tuberculosis. Study was done from July 2009 until September 2010, in Immanuel hospital Bandung and Stem Cell & Cancer Institute Jakarta. Compared with their healthy spouses the IFN-γ serum level in TB patients was not different statistically, the IFN-γ receptor expression in TB patients was higher (p=0,041), however, the IFN-γ receptor function of TB patients was lower (p=0,011). Correlation analysis showed that the only variable had correlation significantly with pulmonary tuberculosis was low function of IFN-γ receptor (p=0,026,OR 5,56). The expression of IFN-γ receptor in pulmonary tuberculosis patients was higher, while the function of IFN-γ receptor was lower than their healthy spouses. The low function of IFN-γ receptor had significantly correlation with pulmonary tuberculosis. Key Words: Tuberculosis, IFN-γ serum level, IFN-γ receptor expression and function.


2020 ◽  
Vol 2 (2) ◽  
pp. 1
Author(s):  
Jufri Hidayat ◽  
Mei-Chen Lee ◽  
Ming-Der Lee ◽  
Chen-Hsiu Chen

Tuberculosis (TB) remains the highest priority among infectious diseases in the world today with increasing morbidity and mortality every year. Adherence to treatment plays an important role in the success of therapy among TB patients. This study aims to explore the relationship between demographic characteristics, knowledge, and medication compliance behavior among patients with tuberculosis in Indonesia. This study was descriptive correlational and cross-sectional design with the total sample was 150 tuberculosis confirmed in Medan Pulmonary Hospital, Indonesia. In this study found that there is a significant relationship between ethnicity and medication adherence (continues variable) with p = 0.01. Meanwhile when medication compliance behavior was treated as categorical variables, a significant relationship was found between medication compliance behavior and medical history (p = 0.03), smoking (p = 0.005), and alcohol (p = 0.03) among tuberculosis patients in Indonesia. In the multivariate analysis, multiple linear regression was performed which surprisingly shows that education was significantly associated with knowledge of TB (p = 0,02), and ethnicity (0.04).


2021 ◽  
Vol 2 (1) ◽  
pp. 60-70
Author(s):  
Erfan AR. Lainjong

Pulmonary Tuberculosis (pulmonary TB) is an infectious airborne disease caused by the bacterium Mycobacterium tuberculosis, which affect the lower respiratory tract. Education level, smoking, income, and family history were known as risk factors for pulmonary TB. The purpose of this study was to determine the determinants associated with pulmonary TB in the outpatient department of Anutapura General Hospital, Palu. This research was an analytical study with a cross-sectional design. The independent variables in this study were the level of education, smoking status, income, and family contact history, while the dependent variable was pulmonary TB. We enrolled 43 respondents with accidental sampling method. Data analysis using univariate and bivariate analysis. The results showed that there was a relationship between education level and pulmonary TB (p = 0.024), smoking status and pulmonary TB (p = 0.004), income and pulmonary TB (p = 0.001), and family contact history with pulmonary TB (p = 0.001).There is a relationship between education level, smoking status, income, and family contact history with pulmonary TB. It is suggested to the health workers of RSU Anutapura Palu to increase understanding and knowledge of patients regarding the prevention and transmission of pulmonary TB disease.


2020 ◽  
Vol 12 (2) ◽  
pp. 280
Author(s):  
Devi Ristian Octavia ◽  
Primanitha Ria Utami

Treatment non-adherence in tuberculosis (TB) patients is a challenge in TB treatment. This research was an observational analysis study with a cross-sectional design. The population of this study were all tuberculosis patients at Karanggeneng Community Health Center, Lamongan from January to September 2018 who were still undergoing treatment process. Total sampling technique was utilized which obtained 40 patients. The data were collected through a closed questionnaire sheet of the method applied by the MMAS (Morisky Medication Adherence Scale). Then, the data were analyzed by editing, coding, scoring and tabulating. The results showed that 92% of patients adhered to Tuberculosis treatment and their influential perceptions included patients’ belief, family support, and motivation from health personnel. Treatment supporter is very influential on the success of Tuberculosis therapy.


Author(s):  
Citra Dewi Ayu Trisnawati

<em>The compliance control of Lung Tuberculosis patients to Poli Paru is influenced by several factors one of which is the Hospital environmental factors (doctors, nurses, midwives, and other health teams). Nurses are a profession very close to patients, one of the approaches used by nurses is the role of the nurse as an Educator. The purpose of this study was to know the relationship between the role of the Nurse Educator with the compliance control of pulmonary tuberculosis patients in Medika Mulia Hospital, Tuban. The method used in this research was the correlation analytic method with a cross-sectional research design. The research in this study involved 66 pulmonary TB patients in Pulmonary Medika Mulia Hospital of Tuban with the determination of the sample using a systematic random sampling method. Data collection was carried out by questionnaire using </em>Spearman rho<em> test data analysis. From the results of the analysis obtained data with a significance value of 0.003 (p &lt;0.05) which means there was a positive relationship between the role of Educator nurses with compliance with Lung Tuberculosis patient compliance. Therefore, HI was accepted, namely the close relationship between the role of the Educator nurse and the compliance control of Lung Tuberculosis patients in the Pulmonary Poli Medika Mulia Hospital, Tuban.</em><em> The results of this study provided input to nurses in the development of nursing knowledge, specifically the role of nurses as educators in the Pulmonary Poli Medika Mulia Hospital of Tuban to improve control compliance in pulmonary TB patients.</em>


e-CliniC ◽  
2015 ◽  
Vol 3 (1) ◽  
Author(s):  
Widyanita K. Silo ◽  
M. C. P. Wongkar ◽  
Yuanita A. Langi

Abstract: Lung Tuberculosis is an infectious disease that remains as a public health problem. Several studies suggest a significant relationship between smoking and lung tuberculosis. This study aimed to determine the prevalence of smoking in patients of lung tuberculosis in DOTS Polyclinic Prof. Dr R. D. Kandou Hospital, Manado. This was a descriptive cross - sectional study conducted in October 2014. Samples included 57 people. Total of lung tuberculosis patients who smoked were 33 people; 28 were males (84.8 %). In the age group of 56-65 years there were 9 people (27.3 %). The most frequent of jobs were self-employed (8 people; 24.2 %). The results showed that the incidence of smoking in patients of lung tuberculosis approximately 57.9 %. Keywords: lung tuberculosis, smoking.Abstrak: Penyakit TB paru merupakan penyakit infeksi yang masih menjadi masalah kesehatan dalam masyarakat. Beberapa penelitian menyebutkan adanya hubungan yang signifikan antara merokok dengan TB paru. Penelitian ini bertujuan untuk mengetahui angka kejadian merokok pada pasien TB paru di Poliklinik DOTS RSUP Prof. Dr. R. D. Kandou Manado. Desain penelitian adalah cross-sectional terhadap pasien TB paru yang berobat di Poliklinik DOTS RSUP Prof. Dr. R. D. Kandou Manado pada bulan November 2014. Sampel berjumlah 57 orang. Jumlah pasien TB paru yang merokok adalah 33 orang, dimana jenis kelamin terbanyak laki-laki yaitu 28 orang (84,8%). Kelompok umur 56-65 tahun adalah yang terbanyak yaitu 9 orang (27,3%), dan pekerjaan terbanyak adalah wiraswasta 8 orang (24,2%). Hasil dari penelitian ini didapatkan angka kejadian merokok pada pasien TB paru sekitar 57,9% dari keseluruhan data.Kata kunci: TB paru, merokok


2018 ◽  
Vol 6 (9) ◽  
pp. 1699-1701
Author(s):  
Arlinda Sari Wahyuni ◽  
Noni Novisari Soeroso ◽  
Dian Dwi Wahyuni

AIM: This study aimed to analyse tuberculosis (TB) medication-taking behaviour based on the concept of concordance between health workers and TB patients in Medan, Indonesia. METHODS: This study was an analytical study with a cross-sectional design. A total of 100 patients undergoing TB treatment at several public health centres in Medan City participated in the study. RESULTS: The results showed that there was a relationship between the concordance behaviour of the health workers with the attitude and medication-taking behaviour of the patients (p < 0.05). However, there was no relationship found between concordance and knowledge of the patients (p > 0.05). CONCLUSION: The results showed that most of the concordance behaviour, knowledge, attitude, and behaviour in the sample were good.


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