scholarly journals Standardization of Arka Kalpana- A Review.

Author(s):  
Swaranjali R. Kaswa

India have a rich heritage of traditional medicinal system from centuries. Ayurveda is a boon for us given by this rich cultured heritage. We use various forms of medicine either traditional ayurvedic formulations (Panchavidhakashay kalpana, asava , arishta, pottali kalpana etc) or modern formulations (syrups, capsules, soft gel capsules, drop formulations etc) in day to day practice. Some formulations explained in Ayurvedic texts lag behind either due to lack of appropriate study or these formulations are not used widely. One of such formulation is Arka kalpana. ‘Arka kalpana’ is explained in details by author Ravana in the text ‘Arkaprakash’. Here it will be explored in details and its standardization techniques will be elaborated . Drug standardization means to confirm its identity, quality and purity throughout all phases like drug collection, processing, storage, distribution etc. Standardization of Arka kalpana can be done in three stages – Raw material standaridization, process standardization and finished product standardization. The outcome of Standardization of Arka kalpana is that a quality, potent, effective formulation of medicine will be available in market with better patient compliance which is need of the hour.

2020 ◽  
Vol 11 (4) ◽  
pp. 6663-6667
Author(s):  
Kamath Madhusudhan ◽  
Bhavana B. Bhat

Traditional medicines have been used since the beginning of human life on earth. Traditional medicines form a part of the household not only in India but also in western countries. According to WHO, traditional medicines are those extracts from plants which are of medicinal value. Around 80% of the world's population relies on traditional medicines for medicinal purposes or as neutraceuticals. There is a well-established procedure for conducting clinical trials of western medicine, but when in the case of traditional medicines, there are several obstacles in the path. Where traditional medicines are the oldest form of medicines used by human's specific issues like lack of infrastructure, lack of sponsors and lack of skilled manpower hinders the clinical trial process for traditional medicines. The articles focus on various issues for conducting clinical trials and the steps taken by the government to address these issues. Centres like the National Center for Complementary and Alternative Medicine, All India Institute of Medical Sciences are working rigorously to research traditional medicine to establish safety and efficacious data at par with modern medicines. Standardization of the collected raw material, in-process standardization and quality control check of the final product will further help in reducing the harmful adverse effects.


2019 ◽  
Vol 18 (7) ◽  
pp. 74-86
Author(s):  
Pavel V. Volkov ◽  
Oleg A. Mitko ◽  
Yuliy S. Gubar ◽  
Roman V. Davydov ◽  
Ivan S. Polovnikov

Purpose. The article presents results of studying the elemental composition and manufacturing technology of turquoise jewelry found in barrow 1 of the Ak-Dag I burial ground of the early Scythian time. Scanning electron microscopy and energy dispersive X-ray spectroscopy were used to determine the elemental composition of the mineral. The presence and ratio of the number of elements in the table indicates that the items are made of turquoise. The basic elements of the mineral include oxides of copper, phosphorus, aluminum and iron. A relatively large amount of iron oxide gives turquoise minerals a more saturated green color. The composition of the samples under study is extremely rich in zirconium, which allows us to identify the field where the raw material was obtained. Results. A traceological study of the artifacts considered was based on the proven methodology of experimental-traceological analysis. As a result of experimental and technological research, we conclude that the process of manufacturing occurred in three stages. Initially, the formation of the main planes of the workpieces and grinding of the ends took place. At the second stage the artifacts were drilled, the starting points of drilling were located at the narrow ends of the items. The traces of work that are visible on the artifacts indicate the use of easel, high-speed drilling. At the third stage the artifacts were processed with a fine-grained abrasive, as a result of which the final products were given a smoothed shape. Conclusion. In general, the production technology of the artifacts considered can be described as relatively perfect. There were closest analogues of the products from the Ak-Dag I site found in the same region. A similar method of inclined drilling was also used by the Scythians of Altai on their stone products.


2020 ◽  
Vol 13 (02) ◽  
pp. 131
Author(s):  
Denny Anggara ◽  
Meassy Shawitry Harianja ◽  
Alvika Musfitasari ◽  
Martha Marselinha ◽  
Fransiskus Xaverius Arif Wahyudianto ◽  
...  

Rambutan production in Indonesia in 2017 is 523,699 tons. Consuming rambutan fruit will affect rambutan peel as a waste. Although rambutan peel has the potential to be made into herbal brew drinks products. The research aims were to determine the productivity of rambutan peel as a raw material for herbal beverage and estimate the benefits to be obtained. The study used local rambutan fruit raw material. The research was carried out in the Forest Product Laboratory of Dipterocarps Research Center. The research aimed to determine the processing technology of rambutan peel as raw material for herbal beverage and estimated benefits to be gained. The research was conducted in three stages of activity, i.e. calculation of the potential of rambutan peel as raw material for herbal beverage, making of rambutan herbal beverage and estimated its profit. Rambutan peel can be processed into herbal brew drinks using simple technology, by making the rambutan peel into a dry powder and put it into a brewed beverage bag. The brewed beverage packaged in 1 box about 3 bags and each bag containing @ 1.5 g herbal beverage. The estimated profit of 1 box of herbal beverage was about 30.4% of the selling price. Keywords: herbal brew drinks, home industry, marine tea, rambutan peel


Author(s):  
Sudirman Kimi ◽  
Abdullah Abuzar Alghafari

In the development of concrete technology (Concrete Technology) today which is increasingly unceasingly, along with the development of the era hence the quality of concrete selection as the main raw material of building construction is very important. This research writer take silica fume and glenium sky as added concrete mixture to know the influence of the addition of silica fume and glenium sky to the compressive strength of concrete. The research is divided into three stages : material testing, test object making and test object. This research uses cube-shaped specimen with size 15x15x15 cm, with 5 variations, they are normal concrete, silica fume 5%, silica fume 5% + glenium sky 2%, silica fume 5% + glenium sky 4%, and silica fume 5% + glenium sky 6%, which every variations has 3 test specimens with 3 days, 7 days, and 28 days. From laboratorium testing, the characteristics of compressive strength of concrete at age 28 days of normal concrete is 407,2 Kg/Cm2, normal concrete with silica fume 5% is 418,5 Kg/Cm2, normal concrete with silica fume 5% + glenium sky 2% is 435,9 Kg/Cm2, normal concrete with silica fume 5% + glenium sky 4% is 451,9 Kg/Cm2, normal concrete with silica fume 5% + glenium sky 6% is 484,1 Kg/Cm2.


Konversi ◽  
2012 ◽  
Vol 1 (1) ◽  
pp. 34
Author(s):  
Rinna Juwita ◽  
Lailan Rizki Syarif ◽  
Abubakar Tuhuloula

Abstrak-Indonesia merupakan negara agraris dengan produksi padi yang besar, dimana seiring tingginya produksi padi maka semakin tinggi pula potensi limbah padi yang dihasilkan, salah satunya berupa sekam padi yang dapat dimanfaatkan sebagai bahan baku pembuatan furfural. Penelitian ini bertujuan untuk menganalisa pengaruh jenis dan konsentrasi katalisator asam terhadap perolehan furfural, menentukan kadar furfural yang diperoleh dengan menggunakan kedua jenis katalisator asam dalam berbagai variasi konsentrasi serta menentukan jenis dan konsentrasi katalisator asam yang dapat menghasilkan kadar furfural terbesar. Penelitian ini berlangsung dalam tiga tahapan, yaitu tahap persiapan bahan baku, proses hidrolisa dan distilasi. Persiapan bahan baku dilakukan dengan menghaluskan sekam padi hingga 80 mesh kemudian dikeringkan menggunakan oven. Proses hidrolisa menggunakan katalisator asam dilakukan selama 4 jam dengan suhu 85oC, hidrolisat disaring untuk selanjutnya dilakukan pemurnian dengan distilasi. Penelitian dilakukan dengan memvariasikan katalisator asam berupa asam sulfat dan asam klorida dengan konsentrasi 1%, 3%, 5%, 7% dan 9%. Hasil penelitian menunjukkan bahwa sintesis furfural dari sekam padi dapat menghasilkan furfural tertinggi pada katalisator asam sulfat dengan konsentrasi 1%. Adapun kadar furfural yang diperoleh pada katalisator asam sulfat dengan konsentrasi 1%, 3%, 5%, 7% dan 9% berturut-turut sebesar 1,815%; 1,256%;  0,933%; 0,733% dan 0,730%, sedangkan kadar furfural yang diperoleh pada katalisator asam klorida sebesar 1,659%; 1,126%; 0,848%; 0,737% dan 0,726%. Keywords:hidrolisa, distilasi, katalisator asam, furfural Abstract-Indonesia is an agrarian country with a large rice production, where rice production is often high, the potential of rice waste will be higher, one of the waste is rice hull that can be used as raw material for the manufacture of furfural. This research aims to determine the type and concentration of acid catalyst in the manufacture of furfural, and analyze the effect of acid catalyst type and concentration to furfural obtained. This research was done by three stages, namely preparation of raw materials, hydrolysis and distillation process. Preparation of raw materials was started by reducing the rice hull’s size up to 80 mesh and then drying. Acid catalyst hydrolysis carried out for four hours with the operating temperature of 85 oC, then filtered hydrolyzate was purified by distillation. Research was done by varying the acid catalyst in the form of sulfuric acid and hidrochloric acid with the concentration of 1%, 3%, 5%, 7% and 9%. The results showed that the synthesis of furfural from rice hull obtained the highest furfural concentration on the sulfuric acidcatalyst at 1% concentration. The furfural obtained with concentration of 1%, 3%, 5%, 7% and 9% on a sulfuric acidcatalyst respectively at 1.815%; 1.256%; 0.933%; 0.733% and 0.730%, while the furfural obtained on the hydrochloric acid catalyst respectively at 1.659%; 1.126%; 0.848%; 0.737% and 0.726%. Keywords:hydrolysis, distillation, acid catalyst, furfural


2021 ◽  
Vol 1 (9) ◽  
pp. 351-356
Author(s):  
Reni Putri ◽  
Robert Junaidi ◽  
Mustain Mustain

Dengan kadar selulosa yang tinggi, fiber cake kelapa sawit dapat digunakan sebagai bahan baku pembuatan nitroselulosa. Percobaan ini bertujuan untuk menghasilkan nitroselulosa dari ?-Selulosa fiber cake kelapa sawit yang memiliki yield produk dan kadar nitrogen yang tinggi dengan waktu yang singkat. Percobaan dilakukan melalui tiga tahapan yaitu tahap pre-treatment bahan baku, tahap pembuatan nitroselulosa melalui proses nitrasi dan tahap analisis produk nitroselulosa. Konversi ?-selulosa fiber cake kelapa sawit menjadi nitroselulosa dilakukan dengan variasi asam penitrasi dengan perbandingan H2SO4 98% dengan HNO3 70% sebesar 1:1, 1:2, 1:3, 1:4 dan 1:5, waktu reaksi pada proses nitrasi selama 30 dan 40 menit serta variasi.suhu proses nitrasi 10-15oC dan 15-20oC. Dari hasil penelitian diketahui bahwa kondisi optimal proses pembuatan nitroselulosa dari fiber cake kelapa sawit dicapai pada rasio asam penitrasi sebesar 1:1 dengan suhu nitrasi 15-20oC dan waktu nitrasi selama 40 menit. Pada kondisi ini diperoleh yield sebesar 95,0% dengan kadar nitrogen sebesar 9,9%.    With high cellulose content, fiber cake palm oil can be used as a raw material for the manufacture of nitrocellulose. This experiment aims to produce nitrocellulose from fiber cake palm oil which has high yield product and high nitrogen content. The experiment was carried out in three stages, namely the pre-treatment of raw materials, the stage of making nitrocellulose through the nitration process and the analysis stage of the nitrocellulose product. The conversion of ?-cellulose fiber cake into nitrocellulose was carried out by varying the acid nitrate with a ratio of H2SO4 98% with HNO3 70% at 1:1, 1:2, 1:3, 1:4 and 1:5, The reaction is in the nitration process for 30 and 40 minutes and the variation of the nitration process temperature is 10-15oC and 15-20oC. From the results of the study it is known that the optimal conditions for the process of making nitrocellulose from fiber cake palm oil are achieved at a nitrating acid ratio of 1 :1 with a nitration temperature of 15-20oC and a nitration time of 40 minutes. In this condition, yield of 95,0% was obtained with nitrogen content of 9,9%.


2017 ◽  
Vol 17 (2) ◽  
pp. 158-179 ◽  
Author(s):  
Sanjay Choudhari ◽  
Amit Tindwani

Purpose This study aims to assist the project manager in minimising the material logistics cost of road project by planning the optimal movement of aggregate across three stages of supply chain: sourcing, processing and distribution. Design/methodology/approach The paper conceptualises the raw material consumption in a road project as a logistics network distribution problem. A linear programming (LP) formulation is constructed with appropriate decision variables by integrating the three stages of material movement. The series of LP scenarios are solved using an LP solver to decide the optimal movement of the aggregate to be consumed in different layers of road segments. Findings The results obtained from the model show that planning material logistics of an entire road project using optimisation provides substantial saving in logistics costs than using common sense. Further, the magnitude of cost saving improves as the complexity of the model increases in term of enormous feasible options. Practical implications The model shown in this paper may serve as a basis for planning the logistics of raw materials consumed in the road projects. The small improvement in material flows by optimising supply chain shows sensible cost benefit to the project manager and hence control and monitor the overall cost and activities of the project. The output of the model is also expected to help the project team as an input in the decision-making processes such as appropriate material sourcing contract, capacity assessment of material processing facility and transportation planning. Originality/value While the optimisation models are widely used and popular among the many industrial applications, this research shows distinct application of such a model in managing the logistics of the road construction project.


Author(s):  
K. Tsuno ◽  
T. Honda ◽  
Y. Harada ◽  
M. Naruse

Developement of computer technology provides much improvements on electron microscopy, such as simulation of images, reconstruction of images and automatic controll of microscopes (auto-focussing and auto-correction of astigmatism) and design of electron microscope lenses by using a finite element method (FEM). In this investigation, procedures for simulating the optical properties of objective lenses of HREM and the characteristics of the new lens for HREM at 200 kV are described.The process for designing the objective lens is divided into three stages. Stage 1 is the process for estimating the optical properties of the lens. Firstly, calculation by FEM is made for simulating the axial magnetic field distributions Bzc of the lens. Secondly, electron ray trajectory is numerically calculated by using Bzc. And lastly, using Bzc and ray trajectory, spherical and chromatic aberration coefficients Cs and Cc are numerically calculated. Above calculations are repeated by changing the shape of lens until! to find an optimum aberration coefficients.


Author(s):  
S. Mahajan

The evolution of dislocation channels in irradiated metals during deformation can be envisaged to occur in three stages: (i) formation of embryonic cluster free regions, (ii) growth of these regions into microscopically observable channels and (iii) termination of their growth due to the accumulation of dislocation damage. The first two stages are particularly intriguing, and we have attempted to follow the early stages of channel formation in polycrystalline molybdenum, irradiated to 5×1019 n. cm−2 (E > 1 Mev) at the reactor ambient temperature (∼ 60°C), using transmission electron microscopy. The irradiated samples were strained, at room temperature, up to the macroscopic yield point.Figure 1 illustrates the early stages of channel formation. The observations suggest that the cluster free regions, such as A, B and C, form in isolated packets, which could subsequently link-up to evolve a channel.


2001 ◽  
Vol 60 (1) ◽  
pp. 11-14 ◽  
Author(s):  
Lucia Savadori ◽  
Eraldo Nicotra ◽  
Rino Rumiati ◽  
Roberto Tamborini

The content and structure of mental representation of economic crises were studied and the flexibility of the structure in different social contexts was tested. Italian and Swiss samples (Total N = 98) were compared with respect to their judgments as to how a series of concrete examples of events representing abstract indicators were relevant symptoms of economic crisis. Mental representations were derived using a cluster procedure. Results showed that the relevance of the indicators varied as a function of national context. The growth of unemployment was judged to be by far the most important symptom of an economic crisis but the Swiss sample judged bankruptcies as more symptomatic than Italians who considered inflation, raw material prices and external accounts to be more relevant. A different clustering structure was found for the two samples: the locations of unemployment and gross domestic production indicators were the main differences in representations.


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