Effectiveness of Intensive Health Education on Tuberculosis Awareness, Attitude and Practice on Pulmonary Tuberculosis among Patients with Pulmonary Tuberculosis

2021 ◽  
pp. 461-466
Author(s):  
T. Nanthini ◽  
Karaline Karunagari
Keyword(s):  
Health Education ◽  
Pulmonary Tuberculosis ◽  
Demographic Variables ◽  
Control Group ◽  
Attitude Score ◽  
Primary Health ◽  
Attitude And Practice ◽  
Primary Health Centres ◽  
The Mean ◽  
Experimental Group

Tuberculosis is an infectious disease which spreads from one person to another which has a devastating impact on the economic well-being of the individual, their families, and the entire community. The effective engagement of all health care providers especially nursing personnel, play an important role to scale up and commensurate to their presence to achieve universal access to tuberculosis care. Majority of times, the nursing personnel were the first person to be contacted, to take care of the patients with tuberculosis. The aim of the study is to evaluate the effectiveness of intensive health education on Pulmonary tuberculosis among patients with newly diagnosed Pulmonary tuberculosis from the four primary health centres as Mettupalayam, Lawspet, Reddiarpalayam and Mudaliarpet under RNTCP (April 2017-February 2018), in Puducherry. The objectives of the study is to assess the tuberculosis awareness, attitude and practice of the subjects among the experimental and control group before and after the intervention, to evaluate the effectiveness of intensive health education and to find out the association between the pretest level of tuberculosis awareness, attitude and practice of the subjects with selected demographic variables. Pre experimental study was adopted. For the purpose of this study, a total of 126 subjects of newly diagnosed pulmonary tuberculosis were under RNTCP(October 2016 to February 2018) selected from the four primary health centres by using cluster stage sampling technique. The investigator explained the purpose of the study to the subjects. The pretest was conducted by using the interview method for all the subjects following that implementation of nursing strategies as intensive health education on health promotion and management of pulmonary tuberculosis, distribution of self-instructional module. Continuous follow up of the subjects every week till 2 months and the posttest-I was conducted by using the same questionnaire after 2 months i.e. end of the intensive phase and again posttest-II was conducted by using the same questionnaire after 6 months i.e. at the end of the continuous phase. The findings of the study as out of 126 subjects, the mean score of tuberculosis awareness score was 9.04±3.65 in the experimental group and 8.32±3.13 of them in the control group. The mean score of attitude towards tuberculosis was 28.38±4.60 and 29.72±5.05 of them in the control group. The mean level of tuberculosis awareness score in the experimental group was 9.04 during pretest and increased to 19.13 in posttest I and further increased to 21.57 in posttest II. But in the control group, the mean tuberculosis awareness score was 8.32 during the pretest and increased to 14.50 in posttest I and 14.84 in posttest II which indicated that there was an increase in the level of tuberculosis awareness score from pretest to posttest II in the experimental group which was significant at p<0.001 level. The mean attitude score in the experimental group was 28.38 during the pretest and increased to 46.80 in posttest I and 57.41 in posttest II and in the control group 29.72 during the pretest and increased to 29.19 in posttest I and 32.24 in posttest II which indicated there was increase in the level of attitude score which was statistically significant at p<0.001 level. The mean practice score in the experimental group was 13.97 during pretest and increased to 20.51 in posttest I and 24.51 in posttest II and in control group 13.51 during the pretest and increased to 18.69 in posttest I and 17.53 in posttest II. The mean values clearly indicated that there was an increase in the practice score which was statistically significant at p<0.001 level. The increased level of Knowledge, attitude and practice score which confirmed that the intervention was much effective in the experimental group when compared to the control group. The Kruskal-Wallis test revealed that there was a significant association between the tuberculosis awareness score of the subjects with selected demographic variables such as the source of information heard about DOTS was statistically significant at p<0.05 level, attitude score of the subjects with selected demographic variable as a marital status which was significant at p<0.05 level than other variables and the practice score of the subjects with gender which was highly significant at p<0.05 level. They concluded that the treatment outcome of the subjects under RNTCP was cured and the cure rate is 100% both in the experimental group and in the control group. Nursing strategies as intensive health education, self-care module along with anti tuberculosis drugs were found to be more effective in improving the tuberculosis awareness, attitude, practice of the subjects in the experimental group than the control group.

THE IMPACT OF EDUCATION ON KNOWLEDGE, ATTITUDE AND PRACTICE OF FOOD VENDORS IN ABIA STATE NIGERIA

2021 ◽  
Vol 8 (1) ◽  
pp. 124-141
Author(s):  
Dora Akinboye ◽  
◽  
Ndu-Agomuo Lois ◽  
Keyword(s):  
Knowledge Score ◽  
Developed Countries ◽  
Control Group ◽  
Attitude Score ◽  
Attitude And Practice ◽  
The Mean ◽  
The Difference ◽  
The Impact ◽  
Experimental Group ◽  
Knowledge Attitude And Practice

Educational intervention on food industry personnel on hygiene has been recommended as a means of improving food handling practices and food safety. This is because human handling errors are responsible for the major outbreaks of food poisoning and food-borne illnesses in developing and developed countries. The study aim toassess the impact of education on knowledge, attitude and practice of food vendors in study Areas in Abia State Nigeria. This study adopted a quasi-experimental study research design which involved one experimental group and one control group for the selection of the 52 food handlers in the five selected Local Government Areas in Abia State. Data were collected using a pretested semi-structured interviewer administered questionnaire and an observational checklist. Descriptive analysis was done with frequencies and summary statistics, T-test and independent sample test was computed to determine the mean difference and significant relationship of variables. Level of significance was set at 0.05 significant levels.Themean knowledge score of the control group was 4.02 ± 1.55 while the mean knowledge score of the experimental group was 7.92 ± 2.50 before the intervention. The difference between the means of the two groups was statistically significant (t=9.28; p=0.000). Also, the mean attitude score was 37.58 ± 3.31 in the control while mean attitude score was 37.79 ± 5.10 in the subjects. The difference between the groups was not statistically significant (t=0.24; p=0.813). The mean practice score was 8.21 ± 2.69 in the control group while the mean practice score was 8.73 ± 4.76 in the experimental group. The difference between the groups was not statistically significant (t=0.67; p=0.506).After the intervention, the mean knowledge score for the experimental group was 9.02 ± 1.58 while that of the control group was 5.55 ± 1.54. The difference between the group was statistically significant (t= 11.03; p=0.000). The mean attitude score for the experimental group was 40.33 ± 4.10 while that of the control group was 41.81 ± 1.963. The difference between the groups was statistically significant (t=2.26; p=0.026). Educational and training programs should be implemented to influence the food vendors’ knowledge, attitude, and practice positively.

Effectiveness of social media for weight reduction on overweight undergraduate students in Thailand

2019 ◽  
Vol 34 (2) ◽  
pp. 90-99
Author(s):  
Tummatida Pattanapongsa ◽  
Wiroj Jiamjarasrangsi ◽  
Piya Hanvoravongchai ◽  
Dumrongsak Pekthong
Keyword(s):  
Social Media ◽  
Weight Loss ◽  
Health Education ◽  
Undergraduate Students ◽  
Support Services ◽  
Control Group ◽  
Content Type ◽  
Online Social Media ◽  
The Mean ◽  
Experimental Group

Purpose Addressing overweight in the population is an important public health challenge. Use of social media such as Facebook has been proposed as a platform to deliver weight loss interventions to influence behavior change to tackle obesity. The purpose of this paper is to compare the effectiveness of weight loss education and support interventions delivered through online social media (experimental group) vs conventional method (control group). Design/methodology/approach The six-month experimental study comprised of a four-month intervention and a two-month follow up from May 2016 to October 2016. All faculties in a university were randomly selected into the experimental or control group. Then, undergraduate students (n=66) were randomly recruited from each faculty into the corresponding groups (experimental group=33 and control group=33). Both groups received health education and support services through either Facebook or the offline support system. The mean differences of main outcomes including body mass index (BMI) and waist to height ratio (WHtR) between groups at baseline and fourth month and baseline and sixth month were compared using t-test. Findings The results show those in the experimental group had significantly better outcomes in term of BMI and WHtR at the end of four-month intervention with the mean difference (95% CI) at 0.7 (0.1, 1.3) and 0.01 (0.00, 0.01), respectively. The differences at the end of the study, however, became insignificant. Originality/value The health education and support services through Facebook can be used in a weight loss promotion program for BMI and WHtR reduction. On a larger scale to replace conventional programs, a long-term continuous measure is needed.

scholarly journals Effect of Ambulation during First Stage of Labor on Labor Pain and Outcome of Labor among the Primigravida Mothers in a Selected Hospital, Mangalore

2013 ◽  
Vol 5 (1) ◽  
pp. 1-3
Author(s):  
V Savitha ◽  
Sabitha Nayak ◽  
Shynee Paul
Keyword(s):  
Demographic Variables ◽  
Labor Pain ◽  
Normal Vaginal Delivery ◽  
Control Group ◽  
Control Groups ◽  
Significant Difference ◽  
The Mean ◽  
And Control ◽  
Experimental Group ◽  
First Stage Of Labor

ABSTRACT Objectives • To assess the intensity of labor pain and outcome of labor among the control group. • To assess the effectiveness of ambulation on intensity of labor pain and outcome of labor among the experimental group. • To assess the usefulness of ambulation by opinionnaire among experimental group. • To compare the effectiveness of ambulation on the intensity of labor pain and outcome of labor among experimental and control groups. • To find an association between the intensity of labor pain with selected demographic variables. Materials and methods An experimental research approach was used for the study. Random sampling technique was used to allocate the subjects into experimental and control groups. Visual analog scale was used to assess the intensity of pain and observational check list was used to assess the outcome of labor. The study comprised of 40 primigravida mothers and they were grouped as experimental and control through randomization. One group received ambulation treatment, the other did not. The researcher then observed the groups to determine the effect of the treatment. Results The collected data was analyzed by descriptive and inferential statistics. The intensity of pain revealed that 40% in the experimental and 55% in the control groups experienced severe pain. The labor augmentation revealed that both oxytocin and cerviprime gel was used for 30% in the experimental and 35% in the control groups. On the mode of delivery, majority of mothers (60%) had normal vaginal delivery both in experimental and control groups. On the duration of the first stage of labor revealed that 50% in the experimental and 20% in the control groups were between 10 to 12 hours. Second stage of labor revealed that majority were between 1 and 2 hours in both the control and experimental groups. The opinion of experimental group mothers on ambulation revealed that half of the mothers (50%) agreed for recommending the ambulation for their neighbors and friends and less than half (35%) of them have agreed for comfort during first stage of labor and 40% of them have agreed for ambulation should be made as a routine in labor room. In the experimental group, mean pain score (6.8) is less than the control group (7.5). The calculated Mann-Whitney Z-value (2.045) is greater than the Z α-value of 1.960 at 0.05 level of significance. In the experimental group, the mean duration of first stage of labor score (3.95) is significantly higher than the control group mean score (3.00). The mean outcome of labor in experimental group (13.95) is greater than the control group. Conclusion There was a significant difference in the duration of first stage of labor between the experimental and control groups. But, there was no significant difference in the overall outcome of labor between experimental and control groups. There was no significant association between intensity of labor pain with selected demographic variables. This may be because of small sample size. How to cite this article Savitha V, Nayak S, Paul S. Effect of Ambulation during First Stage of Labor on Labor Pain and Outcome of Labor among the Primigravida Mothers in a Selected Hospital, Mangalore. J South Asian Feder Obst Gynae 2013;5(1):1-3.

scholarly journals EFEKTIVITAS INTERVENSI PSIKOEDUKASI TERHADAP KEPATUHAN BEROBAT PASIEN SKIZOFRENIA

2018 ◽  
Vol 1 (1) ◽  
pp. 1
Author(s):  
Neila Sulung ◽  
Nice Foresa
Keyword(s):  
Health Education ◽  
Treatment Compliance ◽  
Control Group ◽  
P Value ◽  
Control Group Design ◽  
Psychosocial Therapy ◽  
Significant Difference ◽  
The Mean ◽  
And Control ◽  
Experimental Group

<p><em>Psychoeducation is one form of intervention, both for families and clients who are part of the psychosocial therapy. Psychoeducation aims to increase knowledge about schizophrenia patients and families and to improve treatment compliance</em><em>. </em><em>This study aims to determine the effectiveness of psychoeducation intervention </em><em>for </em><em>treatment compliance</em><em> of </em><em>schizophrenia patient. </em><em>The kind of this research is q</em><em>uasiexperimen</em><em>tal</em><em>with control group design with </em><em>16 samples that was</em><em> selected by pusposive sampling</em><em>,</em><em> consist of </em><em>8</em><em> people</em><em> was the </em><em>experimental group </em><em>that was given </em><em>psychoeducation intervention and </em><em>8 people was the </em><em>control group </em><em>that was </em><em>given health education. </em><em>The d</em><em>ata</em><em>was </em><em>collected by </em><em>filled the </em><em>observation sheet as much as 12 statement</em><em>s</em><em>. </em><em> The </em><em>Test </em><em>that </em><em>used was T-Test Independent with p </em><em>value </em><em><span style="text-decoration: underline;">&lt;</span></em><em>0.05. </em><em>The result of this research is the mean of treatment compliance on experimental group is 11,00 and control group 6,88. In statistic test showed that there is the significant difference between treatment compliance of schizopheria patient on experimental group and control group with p value 0,0005 (p &lt; 0,05).Based of the result above can be concluded than psychoeducation intervention more effective to increase the treatment compliance of schizophrenia patients than health education. It is recomended to the nurse in health center to implements this psychoeducation regularly in gives nursing care to schizophrenia patients.</em></p><p><em> </em></p><p><em>Keyword</em><em>s         : </em><em>psychoeducation, treatment compliance, schizophrenia</em><em></em></p>

scholarly journals EFFECT OF LAVENDER OIL MASSAGE ON PAIN PERCEPTION DURING FIRST STAGE OF LABOUR AMONG PRIMI PARTURIENTS

2021 ◽  
Vol 9 (5) ◽  
pp. 1294-1302
Author(s):  
Kirti Singh ◽  
◽  
Sonia Agnes Singh ◽  
Keyword(s):  
Pain Perception ◽  
Demographic Variables ◽  
Control Group ◽  
Lavender Oil ◽  
Significant Difference ◽  
Post Test ◽  
The Mean ◽  
And Control ◽  
Experimental Group ◽  
Test Level

STATEMENTA study to assess the effect of lavender oil massage on pain perception during first stage of labour among primi parturients admitted in selected hospital, Lucknow. Introduction: Pain in labor is a nearly universal experience for child bearing women. Labor pain is a challenging issue for nurses designing intervention protocols. Pain during labor is caused primarily by uterine muscle contractions and somewhat by pressure on the cervix. This pain manifests itself as cramping in the abdomen, groin, and back. Other causes of pain during labor include pressure on the bladder and bowels by the babys head and stretching of the birth canal and vagina. Labor events have got great psychological, emotional, and social impact to the women and her family. She experiences stress, physical pain, and fear of dangers. The care giver should be tactful, sensitive and respectful to her. Throughout labor she is given continued encouragement and emotional support and assurance are given to keep up the morale.Lavender oil used for aromatherapy is a very versatile essential oil that can be used throughout labour to promote relaxation. It provides a sedation effect to the central nervous system and relieves headache, nervous tension and balances mood swings. According to the American Pregnancy Association, lavender can help create a tranquil, relaxing atmosphere which can reduce pain and stimulate contraction of uterus Objectives Of The Study: 1. Assess the effect of lavender oil massage on pain perception during first stage of labour among primi parturients of experimental group. 2. Compare the post test level of pain perception between primi parturient of experimental group and control group. 3. Associate the level of pain during first stage of labour among primi parturients of experimental group with selected demographic variables. Research Methodology: This study was conducted using Quantitative approach at Integral Hospital, Lucknow. Quasi experimental research design (post test with control group design) was used in the study. The conceptual framework used in this study was Callista Roys Adaptation Model (1991). The total sample size was 30 (15 in experimental group and 15 in control group) selected by convenience sampling technique. Demographic variables were obtained by structured interview and the level of pain was assessed by modified visual analogue scale Reults: The data obtained are tabulated and analyzed using descriptive and inferential statistics. The statistical analysis of the data showed that the mean post test level of pain perception in control group is higher than the mean post test level of pain perception in experimental group. The mean score of experimental group is 2.2(68%) with SD0.41and mean score of control group is 2.8(88%) with SD 0.35 the mean difference is 0.4. The calculated t value is 4.31 at p<0.05 which is more than the table value at 0<0.05. Therefore the null hypothesis H01 is rejected. So the research hypothesis H1 was accepted Conclusion: The findings revealed that there was a significant difference between the level of pain perception among experimental group and control group. It also showed that there was no association of the level of pain during first stage of labour among primi parturients of experimental group with selected demographic variables.

Rorschach Characteristics in Adolescents with Systemic Lupus Erythematosus

2006 ◽  
Vol 28 (1) ◽  
pp. 100-118 ◽  
Author(s):  
J. Santoantonio ◽  
L. Yazigi ◽  
E. I. Sato
Keyword(s):  
Lupus Erythematosus ◽  
Case Control Study ◽  
Activity Index ◽  
Disease Activity Index ◽  
Female Adolescents ◽  
Control Group ◽  
Intelligence Scale ◽  
The Mean ◽  
Experimental Group ◽  
Control Study

The purpose of this study was to investigate the personality characteristics in adolescents with SLE. The research design is a case-control study by means of the Rorschach Method and the Wechsler Intelligence Scale. Study group: 30 female adolescents with lupus, 12–17 years of age. The SLE Disease Activity Index was administered during the period of psychological evaluation. Control group: 32 nonpatient adolescents were matched for age, sex, and socioeconomic level. In the Wechsler Intelligence Scale the mean IQ of the experimental group was significantly lower than that of the control group (77 and 98, respectively, p < .001). In the Rorschach, the lupus patients showed greater difficulty in interpersonal interactions, although they displayed the resources to process affect and to cope with stressful situations. A positive moderate correlation (p = .069) between the activity index of the disease and the affect constriction proportion of the Rorschach was observed: the higher the SLEDAI score, the lower the capacity to process affect. There is a negative correlation between the activity index of the disease and the IQ (p = .001): with a higher activity index of the disease, less intellectual resources are available.

Determination some Immunological Aspects in Pulmonary Tuberculosis Patients in Qadisiyah Province

2018 ◽  
Vol 9 (2) ◽  
Author(s):  
Syoof Khowman Alramahy ◽  
Akram Hadi Hamza
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Pulmonary Tuberculosis ◽  
Statistical Difference ◽  
Positive Culture ◽  
Control Group ◽  
Tuberculosis Patients ◽  
Significant Difference ◽  
Lowenstein Jensen ◽  
The Mean ◽  
Igg Level

This study was carried out to study of some immunological aspects among the pulmonary Tuberculosis patients infected with causative agent, Mycobacterium tuberculosis. A Total of 200 sputum samples were collected from patients attending the consultant Clinic for Chest and Respiratory disease center, Diwaniya. Control group (No=15) also included. According to acid fast stain of sputum, the patients were classified as positive (No=91,45.5%) and negative (No=109,54.5, Lowenstein Jensen medium used for the cultivation of samples, on which 70% of sputum samples where positive culture for this microorganism. The grown microorganism were identified as M. tuberculosis, based on positive A.F.B, Niacin producers ,negative for catlase at 68c. The mean IgG level was l184.053±76.684 mg/100 ml in tuberculosis group compared with 1016.533 ± 44.882 mg/100ml in control group, rendering the statistical difference significant. For IgA and IgM levels, they were at mean of 315.880±38.552 mg/100 ml and 119.527±8.464 mg/100 ml in control group compared with 396.358±38.776 mg/100 ml and 134.207±11.696 mg/100 ml in patients group respectively with significant difference

scholarly journals The Impact of Game-Based, Modeling, and Collaborative Learning Methods on the Achievements, Motivations, and Visual Mathematical Literacy Perceptions

SAGE Open ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 215824402110035
Author(s):  
Aziz İlhan
Keyword(s):  
Collaborative Learning ◽  
Control Group ◽  
Conventional Instruction ◽  
Game Based Learning ◽  
Mathematical Literacy ◽  
Learning Methods ◽  
Learning Groups ◽  
The Mean ◽  
The Impact ◽  
Experimental Group

The present study aimed to investigate the effects of geometry instruction activities conducted in nature based on modeling, game-based, and cooperative learning methods on achievement, mathematical motivation, and visual mathematical literacy perceptions of third-grade elementary school students. The present study is a quantitative study conducted with a pre-test/post-test experimental design with a control group. The study was conducted with 61 students (35 students in the experimental group and 26 students in the control group). Modeling-, game-, and collaborative learning-based activities were conducted with the students in the experimental group. It was determined that the achievements of students who were instructed with modeling-based activities in geometry were high when compared to that of the students instructed with collaborative learning- and game-based methods, and those in the control group where no intervention was applied. This group was followed by the game-based and collaborative learning groups. Based on the variable of motivation, the mean motivation of the students in the modeling group was higher when compared to that of the students in the collaborative learning, game-based, and conventional instruction groups. This group was followed by the collaborative and game-based learning groups. Also, based on the visual mathematical literacy perception variable, the mean visual mathematics literacy perception of the students in the collaborative learning group was higher when compared to that of the students in the groups where the modeling, game-based, and conventional instruction methods were used. This group was followed by the modeling and game-based learning groups.

Attitudes of primary health care physician managers toward research: a pre-experimental study

2013 ◽  
Vol 19 (2) ◽  
pp. 171 ◽  
Author(s):  
Saulat Jahan ◽  
Basem Henary
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Training Program ◽  
Research Training ◽  
Attitude Score ◽  
Primary Health ◽  
Study Results ◽  
Post Test ◽  
The Mean ◽  
Conducting Research

Research in primary health care (PHC) is underdeveloped and scarce, especially in developing countries. It is important to understand the attitudes and aspirations of PHC physicians for the promotion of research. The aim of this study was to determine the attitudes of PHC physician managers toward research in Qassim province and to identify barriers that impede performing research in the PHC system. The study was based on social cognitive theory framework, and was pre-experimental with a ‘one-group pre-test–post-test’ design. The study participants were physician managers in PHC administration, Qassim. The participants’ attitudes were measured by adapting statements from the Attitude Towards Research scale. The intervention was the 1-day training program ‘Introduction to Research in Primary Health Care’. A total of 23 PHC physicians participated in the study. The mean age of the participants was 45.4 (±1.6) years, and the mean years of work experience was 16.2 (±2.2) years. Only one participant had an article published in a peer-reviewed journal. The results of the study showed that PHC physicians had a baseline positive attitude toward research that was further enhanced after participating in an introductory research-training program. During the pre-test, out of the total score of 63, the mean score on attitude toward research was 48.35 (±6.8) while the mean total attitude score in the post-test was 49.7 (±6.6). However, the difference was not statistically significant at P < 0.05. The item with the highest score regarded the role of research in the improvement of health care services, while the lowest-scoring item was about support from administration to conduct research. The participants recognised lack of skills, lack of training and inadequate resources as major barriers in conducting research. Our study results suggest that the PHC physicians’ positive attitudes toward research can be further improved through in-service training. To promote research in PHC in Qassim, regular research-training programs and incentives for conducting research should be provided to the PHC physicians.

scholarly journals Clinical and imaging outcomes after intrathecal injection of umbilical cord tissue mesenchymal stem cells in cerebral palsy: a randomized double-blind sham-controlled clinical trial

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Man Amanat ◽  
Anahita Majmaa ◽  
Morteza Zarrabi ◽  
Masoumeh Nouri ◽  
Masood Ghahvechi Akbari ◽  
...  
Keyword(s):  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Cerebral Palsy ◽  
Umbilical Cord ◽  
Intrathecal Injection ◽  
Control Group ◽  
Umbilical Cord Tissue ◽  
The Mean ◽  
And Control ◽  
Experimental Group

Abstract Background This study assessed the safety and efficacy of intrathecal injection of umbilical cord tissue mesenchymal stem cells (UCT-MSC) in individuals with cerebral palsy (CP). The diffusion tensor imaging (DTI) was performed to evaluate the alterations in white-matter integrity. Methods Participants (4–14 years old) with spastic CP were assigned in 1:1 ratio to receive either UCT-MSC or sham procedure. Single-dose (2 × 107) cells were administered in the experimental group. Small needle pricks to the lower back were performed in the sham-control arm. All individuals were sedated to prevent awareness. The primary endpoints were the mean changes in gross motor function measure (GMFM)-66 from baseline to 12 months after procedures. The mean changes in the modified Ashworth scale (MAS), pediatric evaluation of disability inventory (PEDI), and CP quality of life (CP-QoL) were also assessed. Secondary endpoints were the mean changes in fractional anisotropy (FA) and mean diffusivity (MD) of corticospinal tract (CST) and posterior thalamic radiation (PTR). Results There were 36 participants in each group. The mean GMFM-66 scores after 12 months of intervention were significantly higher in the UCT-MSC group compared to baseline (10.65; 95%CI 5.39, 15.91) and control (β 8.07; 95%CI 1.62, 14.52; Cohen’s d 0.92). The increase was also seen in total PEDI scores (vs baseline 8.53; 95%CI 4.98, 12.08; vs control: β 6.87; 95%CI 1.52, 12.21; Cohen’s d 0.70). The mean change in MAS scores after 12 months of cell injection reduced compared to baseline (−1.0; 95%CI −1.31, −0.69) and control (β −0.72; 95%CI −1.18, −0.26; Cohen’s d 0.76). Regarding CP-QoL, mean changes in domains including friends and family, participation in activities, and communication were higher than the control group with a large effect size. The DTI analysis in the experimental group showed that mean FA increased (CST 0.032; 95%CI 0.02, 0.03. PTR 0.024; 95%CI 0.020, 0.028) and MD decreased (CST −0.035 × 10-3; 95%CI −0.04 × 10-3, −0.02 × 10-3. PTR −0.045 × 10-3; 95%CI −0.05 × 10-3, −0.03 × 10-3); compared to baseline. The mean changes were significantly higher than the control group. Conclusions The UCT-MSC transplantation was safe and may improve the clinical and imaging outcomes. Trial registration The study was registered with ClinicalTrials.gov (NCT03795974).

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