BIOECOLOGY AND COMPONENT COMPOSITION OF EPHEDRINE ALKALOIDS IN SPECIES IN THE DZUNGARIAN ALATAU

Vestnik ◽  
2021 ◽  
pp. 247-253
Author(s):  
Л.С. Кожамжарова ◽  
Н.Т. Аблайханова ◽  
З.Б. Есимсиитова ◽  
А.М. Мухитдинов ◽  
Е.Т. Аблайханов

Как показывают данные фармакологических исследований, природные алкалоиды обладают более высоким качеством терапевтического эффекта и срок действия их продолжительнее. При полноценном растительном сырье и достаточных его запасах или при успешной культуре растения тот или иной алкалоид, несомненно, удобнее и экономически выгоднее получать из натурального растительного сырья. В связи с этим практический интерес представляют работы по выявлению и пополнению сведений о фитохимическом составе ценных технических растений флоры Казахстана в свете последних достижений биохимии, биоорганической химии. В статье, для выяснения установление закономерностей изменения количественного содержания и качественного состава эфедриновых алкалоидов от экологических факторов были изучены биоэкологические особенности и выявлены популяции с высоким и пониженным содержанием компонентного состава эфедриновых алкалоидов у видов E.Equisetina в Джунгарском Алатау, а также, установлен полный спектр эфедриновых алкалоидов в вегетативных побегах изучаемого вида. Практическое значение результатов работы является основой для использования сырьевой базы вида E.Equisetina рода Ephedra L., в отечественной фармацевтической промышленности. According to pharmacological data, natural alkaloids have better therapeutic quality and longer duration. If the raw material is full and sufficient, or if the plant culture is successful, some alkaloid is certainly more convenient and economically more profitable to obtain from natural plant raw materials. In this connection, work to identify and complete information on the phytochemical composition of valuable technical plants in the flora of Kazakhstan, in the light of recent advances in biochemistry and bioorganic chemistry, is of practical interest. In the article, to determine the main regularities of changes in the quantitative content and qualitative composition of ephedrine alkaloids from environmental factors, bioecological features were studied and populations with high and low content of the component composition of ephedrine alkaloids in E. Equisetina species in the Dzungarian Alatau were identified. Also, was established the full spectrum of ephedrine alkaloids in vegetative shoots of the studied. The practical significance of the results is the basis for using the raw material base of the species E. Equisetina of the genus Ephedra L. in the domestic pharmaceutical industry.

2020 ◽  
Vol 992 ◽  
pp. 253-258
Author(s):  
M.P. Lebedev ◽  
V.N. Tagrov ◽  
E.S. Lukin

The article deals with the manufacture of modern structural ceramic materials from clay and loam deposits of the Republic of Sakha (Yakutia). The importance and relevance of the development of the production of building materials from local raw materials is emphasized, since this will certainly affect the effectiveness of the construction complex as a whole. The successful development of the construction complex is capable of not only stimulating growth in all sectors of the economy, but also contributes to solving the most pressing social problems. Today, Yakutia has huge reserves of mineral raw materials for the production of a wide range of building materials and products. Of practical interest are wall materials made from clay soils. Given the features of the region’s raw material base, this work focuses on additional processing of traditional material. Controlling the complex physicochemical and structural-mechanical transformations that occur during heat treatment, a methodology has been developed for creating a composite material that will allow competitive innovative materials with enhanced strength properties to be produced with a reinforcing element with a glassy phase matrix of mullite crystals. The fabricated samples have a wide range of physical and mechanical properties and allow using it as a high-quality structural building ceramics, as well as industrial floor technical tile.


2021 ◽  
pp. 70-77
Author(s):  
С. А. Козира ◽  
Т. М. Гонтова ◽  
С. І. Степанова ◽  
В. П. Гапоненко ◽  
В. В. Машталер ◽  
...  

Among the relevant for the modern pharmacy problems, there is a need for the rational complex use of known medicinal plants, as well as the search for new sources of natural biologically active compounds in order to expand the list of official medicinal plants and raw material base. Species of genus Geum L. contain a number of biological active substances and are promising sources of raw materials for the production of antimicrobial, astringent, anti-inflammatory, and hemostatic medicines. Pharmacological activity of these plants results from their multi-component chemical composition, including tannins, flavonoids, macro- and microelements and other compounds. The aim of thе study was to compare the elemental composition of herb and rhizomes with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. of Ukrainian flora. The objects of the study were the samples of herb and rhizome with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. (dried raw materials) which were collected in the Kharkiv region, Ruski Tishki village, in June-August 2018–2019. The determination of the qualitative composition and quantitative content of elements was carried out by atomic absorption spectroscopy with atomization in an air-acetylene flame using a spectrometer CAS 120 («Selmi», Sumy, Ukraine). In the studied samples, 19 elements were determined, including 5 macroelements and 14 microelements. The data about accumulation of elements in investigated herb of G. urbanum L., G. aleppicum Jacq., G. rivale L. can be arranged in descending order as follows: K > Ca > Si > Mg > P > Fe > Al > Na > Sr > Zn, and in rhizomes with roots as follows – K > Si > Ca > Mg > Fe > P > Al > Na > Sr > Zn. The content of toxic elements such as cobalt, cadmium, arsenic, and mercury was within the permissible limits for plant raw materials and food. For the first time, a comparative study of the macro- and microelement composition in herb and rhizomes with roots of G. urbanum L., G. aleppicum Jacq. and G. rivale L. has been carried out. Using the method of atomic absorption spectral analysis, 19 elements have been identified and their content has been determined, among which К, Ca, Mg, Si, P, Fe, Al, Na, Mn, Zn predominantly accumulate.


Author(s):  
Nesterov G.V. ◽  
Litvinova T.M. ◽  
Vasalatiy L.A.

To expand the raw material base of medicinal plant raw materials, a promising area of research is the study of additional types of raw materials that can be harvested from already used medicinal and food plants. Given the complexity of harvesting alder seeds, researchers are interested in the leaves of this plant, a wide range of biologically active substances that cause anti-inflammatory, astringent and antioxidant effects. The first stage of standardization of raw materials is the definition of morphologically significant features, based on the generalization of which the section "External features" is developed. The analysis of morphological features of freshly harvested, dried and frozen leaves of gray alder (Alnus incana Moench) and black alder (A. glutinosa Gaerth) harvested from wild plants in mixed forests of the Moscow region revealed diagnostically significant features and found that the method of conservation does not affect the occurrence of the identified features. Since it is planned to use both types of alder for the preparation of a new type of raw material "Alder leaves", a generalized formulation is proposed for raw materials that are a mixture of species.


Author(s):  
Aitkazinova Sh.A., ◽  
◽  
Bek А.А., ◽  
Derbisov K.T., ◽  
Donenbayeva N.S., ◽  
...  

Results of longstanding researches of Satbayev University scientists on the development of modified building materials to strengthen cracked mountain structures based on industrial waste are considered. Industrial processing of technogenic raw materials (enrichment and processing waste, overburden and enclosing rocks), which is similar in composition to natural and used in conventional trend, scarcely different from industrial processing of mineral raw materials. Creation of effective technologies for the processing of technogenic raw materials is an urgent task, which make it possible to obtain competitive products from it for various industries. Various methods of preparing solutions for strengthening of fractured rocks and building structures are analyzed. Research results of tailings of the Balkhash Mining and Metallurgical Combine and preparing solutions for strengthening fractured rocks and underground mining structures are presented. Rock mass strengthening in cracked areas is achieved by adding substances into the cracks, which after hardening and solidification with rocks, increase its shearing resistance characteristics. The most widespread hardening methods were cementation during mine workings (underground structures) in fractured rocks. Significance of obtained results for construction industry is in expansion and reproduction of raw material base of building materials industry through the use of Mining and metallurgical complex waste (tailings) and development of resource-saving technologies. Practical significance of work is in the detailed development of modified method for the production of building materials and products.


Author(s):  
Р. І. Черьопкіна ◽  
І. В. Трембус ◽  
І. М. Дейкун

The main objectives of scientific work is to study the technological parameters of the sodium hydroxide method  of  delignification  of  non-wood  raw  materials  and  production  of  fibrous  first  stuff   for  the  manufacturing  of packaging types of paper. Methodology. For the research, rapeseed stalks, sodium hydroxide cooking, anthraquinone catalyst were used. The  brews  were  cooked  in  steel  autoclaves,  which  were  lowered  into  a  glycerin  bath.  Standard  methods  for  the determination of the quality indicators (yield and residual lignin content) of non-wood fiber first stuff  were used. As a mathematical  data  processing  method,  the  generalized  reduced  gradient  method  was  used.  Laboratory  samples  of castings of fibrous first stuff  and paper were made on a LA-2 sheet-making apparatus, the mechanical parameters of the outturn sheet were determined according to the standard methods using appropriate instruments. Results. The expediency of using rapeseed stalks for processing of fibrous first stuff  under alkaline conditions has been proven. It was found that the greatest influence on the delignification of raw materials has the raise of cooking temperature from 80 to 120 ° C and the use of the anthraquinone catalyst. It has been shown that the obtained rapeseed first stuff  have sufficient paper-forming properties and are suitable for use in the production of MS 5B brand paper for the use in the production of fluting paper or board of B-3 grade. The scientific novelty of the work is due to the environmental friendliness of the agrowaste processing as an alternative raw material for the production of fibrous first stuff  at low cooking temperatures. Using rapeseed stalks as an example, the influence of technological parameters on the quality indicators of first stuff  was studied. Using the mathematical methods of the processing of experiment data, the optimal ratio of fibrous first stuff /waste paper at which the strength indicators of fluting paper or board will meet the standards was determined. Practical significance. Research results has shown the expediency of using oilseed wastes for processing of fibrous first stuff , with the aim of expanding the raw material base of cardboard and paper production.


Author(s):  
I. A. Ilina ◽  
I. A. Machneva ◽  
E. S. Bakun

  The article is devoted to the study of the chemical composition, physical and thermal-pfysical characteristics of damp apple pomaces and the identifying patterns of influence of drying temperature the functional composition and gel-forming ability of pectin. The research is aimed at obtaining initial data for the subsequent calculation of the main technological, hydro-mechanical, thermal, structural and economic characteristics of devices for drying the plant raw materials, ensuring the environmental safety and high quality of pectin-containing raw materials, the reducing heat and energy costs. As a result of the study of the thermal characteristics of apple pomaces, the critical points (temperature conductivity – 16.5 x 10-8 m2/s, thermal conductivity – 0.28 W/m K, heat capacity – 1627 j/(kg K)) at a humidity of 56 % are determined, which characterizing the transition from the extraction of weakly bound moisture to the extraction of moisture with strong bonds (colloidal, adsorption). It was found that the pomaces obtained from apples of late ripening have a higher content of solids (21-23 %), soluble pectin and protopectin (2.5-4.5 %). Dried pomaces obtained from apple varieties of late ripening contain up to 25 % pectin, which allow us to recommend them as a source of raw materials for the production of pectin. The optimum modes of preliminary washing of raw materials are offered, allowing to the remove the ballast substances as much as possible. It is established that when the drying temperature increases, the destructive processes are catalyzed: the strength of the pectin jelly and the uronide component and the degree of pectin esterification are reduced. The optimum drying temperature of damp apple pomaces is 80 0C, at which the quality of pectin extracted from the dried raw materials is maintained as much as possible. It is shown that the most effective for the pectin production is a fraction with a particle size of 3-5 mm, which allow us to extract up to 71 % of pectin from raw materials.


2021 ◽  
pp. 87-90
Author(s):  
М.Ж. Кизатова ◽  
Д.А. Абдуллаева

Статья посвящена важности пектиновых веществ, а также расширению сферы использования лекарственного растительного сырья. В качестве лекарственного растительного сырья представлены технологии получения пектинового экстракта из плодов шиповника, которые встречаются на территории Казахстана 25 видов. Применение пектина в медицине. The article is devoted to the importance of pectin substances, as well as to the expansion of the use of medicinal plant raw materials. As a medicinal plant raw material, technologies for obtaining pectin extract from rosehip fruits, which are found in 25 species on the territory of Kazakhstan, are presented. The use of pectin in medicine


Author(s):  
I. F. Iskakov ◽  
G. A. Kunitsyn ◽  
D. V. Lazarev ◽  
А. А. Red`kin ◽  
S. A. Trubitsyn ◽  
...  

To use effectively internal raw material base, JSC “Ural Steel” accomplished I category major overhaul of the blast furnace No. 2. The main purpose of the overhaul was to design a rational profile which could ensure an ability to operate with a charge containing 95 % of Mikhailovskii GOK (mining and concentrating plant) pellets having basicity of 0.5 by CaO/SiO2. The blast furnace No. 2 having useful volume of 1232 m3, was constructed by design of Danieli Corus, the Netherlands, and was blown in on December 30, 2020. In the process of guarantee tests, step-by-step increase of Mikhailovskii GOK pellets (Fetotal = 60.5 %, CaO/SiO2 = 0.5) content in the charge iron ore part was being accomplished from 55 to 95.1%. Charging of the blend containing pellets in the amount of 55% of iron ore part, was done by charging system 4OOCC + 1COOCC (Ore - Coke) with filling level 1.5 m. Under conditions of pellets part increase in the blend, the charging system was changed to decrease their content at the periphery, to increase it in the ore ridge zone and make it intermediate between periphery and the ore ridge. At the pellets share in the iron ore raw materials 0.75 the charging system was used as the following: 3OOCC + 1COOC + 1COOCC, while at the content 95.1% the following charging system was used: 2COOC + 2COOC + 1COOCC. It was noted that in the period of guarantee tests the furnace running was smooth. The average silicon content in the hot metal was 0.70% at the standard deviation 0.666. Sulfur content in the hot metal did not exceed 0.024%, the blowing and natural gas consumption figures were 2100 m3/min and 11000 m3/min correspondently, oxygen content in the blowing 26.5%, hot blowing and top smoke pressure figures were 226.5 and 109.8 KPa correspondently. The productivity of the furnace was reached as high as 2358 t/day at the specific coke rate 433 kg/t of hot metal. After guarantee tests completion, the pellets content in the iron ore part was decreased gradually from 95 down to 50%. The decreasing was made by 5% in every 6 hours of operation. Application of the mastered technology of the blast furnace No. 2 with the increased share of pellets will enable to stably supply the blast furnaces No. 1, 3 and 4 by iron ore raw materials in the proportion of 30-35% of pellets and 65-70% of sinter.


2021 ◽  
Vol 316 ◽  
pp. 1050-1054
Author(s):  
V.N. Zyryanova ◽  
E.V. Lytkina ◽  
A.P. Ochur-Ool

Increasing water resistance and mechanical strength of hardening magnesian binders’ products can be achieved by introducing microfillings into a hardening dispersed system. It is shown that serpentine provides an increase strength and water resistance in hydration and hardening process, being as a structure-forming component, it intensifies this process. It allows expanding the raw material base for the production of magnesia binders for construction purposes.


2021 ◽  
Vol 9 (16) ◽  
pp. 90-97
Author(s):  
Kateryna Danilova ◽  
◽  
Oksana Zavarzina ◽  

An actual problem of the alcohol industry development is the expansion of the raw material base through the use of new, cheaper types of carbohydrate sources. Recently, glucose-fructose syrup has been of increasing interest to producers of ethanol. Among the producers of craft drinks, in particular rum-based drinks, cane molasses is in increasing demand. The article presents the technological aspects of the fermentation process of nonconventional sugar-containing raw materials on the example of glucose-fructose syrup and cane molasses in ethanol by different yeast strains. It is determined that glucose-fructose syrup and cane molasses are raw materials depleted of nitrogen, phosphorus and growth substances necessary for the yeast activity. To improve the technological properties of raw materials in the molasses, nitrogen, phosphorus nutrition and corn extract as a growth substance shall be added to a mash. Glucose-fructose syrup is of pH 3.68 and of acidity 0.12, which negatively affects the fermentation. It is established that in order to create optimal living conditions for yeast, it is necessary to add substances to the glucose-fructose syrup that will contribute to the safety of development and prevent the pH 3.5. It was determined that the alcohol yield from 1 ton of glucose-fructose syrup is 31.0 dal, from 1 ton of cane molasses is 24.0 dal on the yeast 46ED and 22 dal on the TegaYeast without the use of growth substances and vitamins necessary for the reproduction of yeast biomass. Under conditions of improving the technological properties of the mash from the glucose-fructose syrup and cane molasses by adding biologically active substances promoting the synthesis of yeast biomass, the ethanol content in the fermented mashes increases up to 11.9 12% vol.


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