Formulasi Sabun Cair Dengan Kombinasi Minyak Kelapa Murni (VCO) dan Ekstrak Daun Miana (Coleus atropurpureus)

Saponification between alkaline salt and virgin coconut oil (VCO) will produce liquid soap. This is because the use of virgin coconut oil (VCO) in saponification is known to be very good because of the presence of lauric acid which has clean power and functions as an antimicrobial. The addition of miana leaf extract (Coleus atropurpureus) in the manufacture of liquid soap because it contains flavonoids, tannins, saponins, essential oils which also function as moisturizers and antioxidants. The purpose of this study was to determine the effectiveness of the best combination of pure coconut oil (VCO) liquid soap with variations in the concentration of miana leaf extract (Coleus atropurpureus) in reducing free radicals in the form of bacteria. In this study, a laboratory experimental method was used with the addition of miana leaf extract. A= 0% (w/w), B= 10% (w/w), C= 15% (w/w),) in 100 mL total virgin coconut oil (VCO) three times. The test parameters were in the form of a bacteriological test using the Total Plate Number (ALT) method. From the results of the study, it was found that the formulation of pure coconut oil (VCO) liquid soap with various concentrations of miana leaf extract (Coleus atropurpureus) could reduce free radicals such as bacteria.

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PEMBUATAN VIRGIN COCONUT OIL DENGAN PENAMBAHAN ENZIM PAPAIN DARI EKSRAK DAUN PEPAYA (Carica papaya)

Jurnal Kimia ◽

10.24843/jchem.2020.v14.i02.p14 ◽

2020 ◽

pp. 192

Author(s):

I W. Suirta ◽

I. A. R. Astitiasih

Keyword(s):

Fatty Acids ◽

Diethyl Ether ◽

Lauric Acid ◽

Leaf Extract ◽

Saturated Fatty Acids ◽

Coconut Oil ◽

Capric Acid ◽

Ethanol Extract ◽

Negative Control ◽

Virgin Coconut Oil

Virgin coconut oil has been made by using papaya leaf extract as a source of the papain enzyme. Papaya leaf extraction with maceration used ethanol 95% as solvent. The crude ethanol extract was purified by means of gradient column chromatography using hexane, diethyl ether and ethanol as solvents. The results showed that using papaya leaf extract could significantly increase the quantity of VCO. Coconut milk cream without treatment (negative control) obtained 3.0042 ± 0.046g of VCO, while treatment with papaya leaf extract gained 6,039 ± 0.049 - 7,952 ± 0.031g of VCO, an increase of about 97.5% - 161%. Based on the medium chain saturated fatty acids (MCFA) and long chain saturated fatty acids (LCFA) in VCO, it indicated that the quality of VCO obtained was not good. VCO in diethyl ether fraction and crude extract etanol produced yellow VCO, indicating chlorophyll was still there. Etanol fraction of VCO provided the best quality with the most of lauric acid content and clear color. The VCO components identified using GCMS analysis obtained several fatty acids such as capric acid, lauric acid, myristic acid, palmitic acid, oleic acid, stearic acid, and stearic epoxy. Keywords: virgin coconut oil, papain enzyme, papaya leaf extract Telah dilakukan pembuatan virgin coconut oil dengan ekstrak daun pepaya sebagai sumber enzim papain. Proses ekstraksi daun pepaya dengan cara maserasi menggunakan pelarut etanol 95%. Ekstrak kasar etanol hasil maserasi dimurnikan dengan cara kromatografi kolom elusi gradient menggunakan pelarut heksana, dietil eter, dan etanol. Hasil penelitian menunjukkan bahwa ekstrak daun pepaya secara signifikan dapat meningkatkan kuantitas VCO. Krim santan tanpa perlakuan (kontrol negatip) didapatkan berat VCO 3.0042±0,046g, sedangkan dengan ekstrak daun pepaya diperoleh berat VCO 6.039±0,049g – 7.952±0,031g, terjadi kenaikan sekitar 97,5% - 161%. Berdasarkan kandungan asam lemak rantai medium dan asam lemak rantai panjang pada VCO, menunjukkan bahwa kualitas VCO yang diperoleh masih kurang baik. Krim santan dengan daun pepaya fraksi dietil eter dan ekstrak kasar etanol menghasilkan VCO berwarna kuning yang mengindikasikan masih terdapat klorofil. VCO fraksi etanol yang memberikan kualitas paling baik dengan kandungan asam laurat paling banyak dan berwarna bening. Komponen VCO yang teridentifikasi dari analisis GCMS diperoleh beberapa asam lemak seperti: asam kaprat, asam laurat, asam miristat, asam palmitat, asam oleat, asam stearat, dan epoksi stearat. Kata kunci: virgin coconut oil, enzim papain, ekstrak daun pepaya

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PEMBUATAN SABUN CAIR BERBASIS VIRGIN COCONUT OIL (VCO) DENGAN PENAMBAHAN MINYAK LAVENDER SEBAGAI ESSENTIAL OIL PENCEGAHAN PENYEBARAN COVID-19”

Jurnal Abdimas Saintika ◽

10.30633/jas.v3i1.1013 ◽

2021 ◽

Vol 3 (1) ◽

pp. 52

Author(s):

Niken ., ◽

Annita ., ◽

Rahmi Novita Yusuf

Keyword(s):

Essential Oil ◽

Lauric Acid ◽

Ph Value ◽

Chemical Properties ◽

Coconut Oil ◽

The Body ◽

Raw Material ◽

Virgin Coconut Oil ◽

Liquid Soap ◽

Lavender Oil

ABSTRAK Pandemi virus corona (Covid 19) saat ini telah melanda berbagai negara di belahan dunia.Upaya yang bisa dilakukan adalah melakukan berbagai upaya pencegahan, salah satunya adalah mencuci tangan menggunakan sabun atau yang sering kita dengar dengan istilah CTPS (Cuci Tangan Pakai Sabun). Program ini meliputi materi penyuluhan tentang pencegahan penularan covid-19, dengan menjaga kebersihan tangan bisa memutus rantai penyebaran covid-19 karena tangan bagian tubuh yang sangat rentan dan dapat dengan mudah menjadi tempat bersarangnya virus dan bakteri. Virgin coconut oil (VCO) merupakan minyak dengan kandungan asam laurat yang tinggi. Asam laurat ini berfungsi untuk menghaluskan dan melembabkan kulit. Sehingga VCO cocok dijadikan sebagai bahan baku pembuatan sabun. Sabun yang dibuat dalam penelitian ini menggunakan penambahan minyak lavender sebagai esensial oil yang mampu meningkatkan kualitas pada sabun cair. Kegiatan ini bertujuan untuk membuat sabun cair, mencari penambahan konsentrasi minyak lavender yang tepat dalam pembuatan sabun cair dan mengetahui pengaruh penambahan minyak lavender terhadap karakteristik sabun cair. Perlakuan pada kegiatan ini konsentrasi minyak lavender adalah dengan penambahan sebesar A = 0% (b/v), B = 1% (b/v), C = 1,5% (b/v), dan D = 2% (b/v) dari 300 gram basis sabun. Parameter pengamatan meliputi sifat kimia, sifat fisik sabun dan uji organoleptik. Hasil analisis menunjukan bahwa semua formula sabun cair memenuhi persyaratan berdasarkan SNI sabun padat 06-4085-1996. Formula sabun cair dengan perlakuan D merupakan produk terbaik dengan hasil uji organoleptik kesukaan secara umum adalah 50%. Hasil analisis sabun transparan pada perlakuan D adalah kadar alkali bebas bebas 0,0079%, nilai pH 8,93, bobot jenis 1,0509 dan angka lempeng total 0. Sehingga teknologi proses pembuatan sabun cair dengan penambahan minyak lavender selanjutnya dapat dikembangkan dan diaplikasikan pada skala industri. Kata kunci : sabun cair, Covid-19, virgin coconut oil (VCO), produksi. ABSTRACT The corona virus pandemic (Covid 19) has currently hit various countries around the world. Efforts that can be done are to make various prevention efforts, one of which is washing hands using soap or what we often hear as CTPS (Washing Hands with Soap). This program includes counseling material on the prevention of covid-19 transmission, by maintaining hand hygiene, it can break the chain of the spread of covid-19 because the hands are very vulnerable parts of the body and can easily become a breeding ground for viruses and bacteria. Virgin coconut oil (VCO) is an oil with a high content of lauric acid. Lauric acid functions to smooth and moisturize the skin. So that VCO is suitable as a raw material for making soap. The soap made in this study uses the addition of lavender oil as an essential oil which can improve the quality of liquid soap. This activity aims to make liquid soap, look for the addition of the right concentration of lavender oil in making liquid soap and determine the effect of adding lavender oil on the characteristics of liquid soap. The treatment in this activity is the concentration of lavender oil with the addition of A = 0% (w / v), B = 1% (w / v), C = 1.5% (w / v), and D = 2% (b / v) of 300 grams of soap base. Observation parameters include chemical properties, soap physical properties and organoleptic tests. The results of the analysis show that all liquid soap formulas meet the requirements based on SNI for solid soap 06-4085-1996. Liquid soap formula with treatment D is the best product with the result of the favorite organoleptic test in general is 50%. The results of the analysis of transparent soap in treatment D were free alkaline content of 0.0079%, pH value of 8.93, specific gravity of 1.0509 and a total plate number of 0. So that the technology for making liquid soap with the addition of lavender oil can then be developed and applied to industrial scale. Keywords: liquid soap, Covid-19, virgin coconut oil (VCO), production.

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The Utilization of VCO (Virgin Coconut Oil) in Manufacturing of Solid Soap with Red Betel Leaf Extract Addition (Paper Crotum Ruiz &Pav)

IOP Conference Series Materials Science and Engineering ◽

10.1088/1757-899x/335/1/012038 ◽

2018 ◽

Vol 335 ◽

pp. 012038

Author(s):

M Sari

Keyword(s):

Leaf Extract ◽

Coconut Oil ◽

Virgin Coconut Oil ◽

Betel Leaf

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Antibacterial Effect of Carvacrol and Coconut Oil on Selected Pathogenic Bacteria

Scientia Agriculturae Bohemica ◽

10.2478/sab-2018-0008 ◽

2018 ◽

Vol 49 (1) ◽

pp. 46-52 ◽

Cited By ~ 1

Author(s):

M. Božik ◽

P. Hovorková ◽

P. Klouček

Keyword(s):

Essential Oils ◽

Lauric Acid ◽

Pathogenic Bacteria ◽

Antimicrobial Agents ◽

Antibacterial Effect ◽

Cocos Nucifera ◽

Coconut Oil ◽

High Concentration ◽

Enterococcus Cecorum ◽

Antibacterial Potential

AbstractEssential oils play a prominent role as flavouring agents and fragrances in the food and perfume industries. Carvacrol is a major component of various essential oils, such as oregano and thyme oils, and is responsible for their antimicrobial activity. Lauric acid is a medium-chain fatty acid (MCFA) with a high antibacterial potential. Both carvacrol and MCFAs have been used empirically as antimicrobial agents. Here, we tested the inhibitory properties of carvacrol and coconut (Cocos nuciferaL.) oil containing a high percentage of MCFAs against 5 harmful bacterial pathogens:Escherichia coli, SalmonellaEnteritidis,Staphylococcus aureus, Listeria monocytogenes, andEnterococcus cecorum. Gas chromatography (GC-FID) analysis of coconut oil showed a high concentration of lauric acid (41%). Microdilution antimicrobial assays showed that the combination of carvacrol and coconut oil had a stronger antibacterial effect against all tested bacteria than both agents separately. We conclude that carvacrol could significantly improve the antibacterial effect of coconut oil.

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Should virgin coconut oil be used in the adjunctive treatment of COVID-19?

Acta Medica Philippina ◽

10.47895/amp.v54i0.1606 ◽

2020 ◽

Vol 54 ◽

Author(s):

Carol Stephanie C. Tan-Lim ◽

Corinna Victoria Martinez

Keyword(s):

Lauric Acid ◽

Animal Studies ◽

Coconut Oil ◽

The Philippines ◽

Adjunctive Treatment ◽

Virgin Coconut Oil ◽

Ssrna Virus ◽

Immunodeficiency Virus ◽

Pharmacologically Active

KEY FINDINGS There is currently no evidence to support the use of virgin coconut oil in the adjunctive treatment of COVID-19. • Virgin coconut oil is naturally extracted from fresh coconut kernel and is rich in medium chain triglycerides, with lauric acid as the predominant fatty acid.• Virgin coconut oil is currently explored as an adjunctive treatment for patients with COVID-19 due to its antiviral and immunomodulatory properties.• In vitro studies show that lauric acid or its derivative exert inhibitory activities against viruses with similar structure to coronavirus (enveloped ssRNA virus) such as Junin virus, vesicular stomatitis virus, human immunodeficiency virus type 1 (HIV-1), and Semliki Forest virus.• Animal studies demonstrate antiviral activity of monolaurin, the pharmacologically active metabolite of lauric acid, on avian influenza virus and Simean immunodeficiency virus, which are both enveloped ssRNA viruses.• Clinical trials among patients with HIV report that virgin coconut oil can increase CD4+ T lymphocyte counts and reduce viral load.• In vitro and animal studies demonstrate anti-inflammatory properties of virgin coconut oil.• At present, there are no studies that investigate the effectiveness of virgin coconut oil in the adjunctive treatment of COVID-19 infection.• There is currently one ongoing clinical trial in the Philippines evaluating the use of virgin coconut oil in the adjunctive treatment of COVID-19.• Nausea, vomiting, mild diarrhea, and abdominal pain have been reported, but no serious adverse events have been identified with the use of virgin coconut oil.• To date, there are no guidelines that mention virgin coconut oil as an option for the adjunctive treatment of COVID-19.

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Effect of virgin coconut oil (VCO) on the physical stability of sweet potato leaf extract (Ipomoea batatas (L.) Lam) creams and antibacterial activity test against Staphylococcus aureus ATCC 25923

Pharmaciana ◽

10.12928/pharmaciana.v11i1.18575 ◽

2021 ◽

Vol 11 (1) ◽

pp. 109

Author(s):

Mauritz Pandapotan Marpaung ◽

Dani Prasetyo

Keyword(s):

Staphylococcus Aureus ◽

Antibacterial Activity ◽

Sweet Potato ◽

Ipomoea Batatas ◽

Leaf Extract ◽

Physical Stability ◽

Coconut Oil ◽

Virgin Coconut Oil ◽

Potato Leaf ◽

Activity Test

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The Effect of Giving Virgin Coconut Oil (VCO) to Changes in Lauric Acid Levels in Breast Milk

JOURNAL OBGIN EMAS ◽

10.25077/aoj.5.2.233-243.2021 ◽

2021 ◽

Vol 5 (2) ◽

pp. 233-243

Author(s):

Ismul Sadly Putra ◽

Joserizal Serudji

Keyword(s):

Fatty Acids ◽

Breast Milk ◽

Lauric Acid ◽

Metabolic Pathways ◽

Saturated Fatty Acids ◽

Coconut Oil ◽

The Body ◽

Virgin Coconut Oil ◽

Nutritional Components ◽

Anti Fungal

Breastmilk (ASI) is the best food produced by the breast glands, containing all the nutritional elements needed by infants aged 0-6 months. Apart from nutrients, breast milk also has other non-nutritional components that act as immune factors for babies. Babies who are not exclusively breastfed will be more susceptible to chronic diseases, such as heart disease, hypertension, and diabetes as adults and can suffer from malnutrition and obesity. Dietary intake significantly affects milk production. The mother's diet can affect the composition of her milk through several metabolic pathways, especially the concentration of fatty acids and vitamins that are soluble in fat and water, including vitamins A, C, B6, and B12. Lauric acid contained in breast milk can help your minor fight infection and increase immunity to protect from various diseases. Not only for the baby, but virgin coconut oil is also starting to be commonly used by dieters. Virgin coconut oil contains lauric acid CH3 (CH2) 10COOH 50% and caprylic acid CH3 (CH2) 6COOH 7%. Both of these acids are medium-chain saturated fatty acids that are quickly metabolized and have anti-microbial properties. The benefits of virgin coconut oil (VCO) are that it is beneficial for the health of the body, including being antibacterial, antiviral, anti-fungal, and natural anti-protozoa; helps relieve symptoms and reduces health risks associated with diabetes, helps protect against osteoporosis, helps prevent high blood pressure, helps prevent liver disease, keeps the heart and blood vessels healthy, helps prevent cancer, helps you lose weight, maintain stamina, maintain healthy skin and hair.Keywords: Breastmilk, Lauric Acid, VCO

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Composition of Fatty Acid and Identification of Lauric Acid Position in Coconut and Palm Kernel Oils

Indonesian Journal of Pharmaceutical and Clinical Research ◽

10.32734/idjpcr.v1i2.605 ◽

2018 ◽

Vol 1 (2) ◽

pp. 1-8

Author(s):

Jansen Silalahi ◽

Lida Karo Karo ◽

Siti Morin Sinaga ◽

Yosy Cinthya Eriwaty Silalahi

Keyword(s):

Fatty Acids ◽

Gas Chromatography ◽

Fatty Acid ◽

Lauric Acid ◽

Nutritional Value ◽

Palm Kernel ◽

Coconut Oil ◽

Fatty Acids Composition ◽

Virgin Coconut Oil ◽

Kernel Oil

The nutritional value and biochemical properties of oil are measured by the fatty acids composition in oil and the position of fatty acids (sn-1,2,3) in the triacylglycerol (TAG) molecule. The purpose of this study was to measure the nutritional value based on the fatty acids composition of virgin coconut oil (VCO) and palm kernel oil (PKO), and the position of lauric acid in sn-2. The VCO used was VCO obtained from one of the Pharmacies store in Medan, and PKO from the Oil Processing Plant. The total fatty acid composition was measured by Gas Chromatography. The nutritional value of fat was evaluated by the percentage deviation from 33.33% (ratio: 1: 1: 1) of each group of fatty acid (saturated fatty acids; SFA: monounsaturated fatty acids; MUFA:polyunsaturated fatty acid (PUFA). The distribution of lauric acid in TAG was conducted through hydrolysis by using specific lipase enzymes active at sn-1,3 positions, so that free fatty acids and 2-monoacylglycerol were produced from one TAG molecule. Then free fatty acids were determined by Gas Chromatography. The distribution of lauric acid at sn-2 position was the difference between total lauric acid on TAG before hydrolysis and free lauric acid from sn-1.3 position after hydrolysis. The results showed that PKO nutritional value was better because of the smaller deviation (95.29%) compared with nutritional value of VCO with a greater deviation (118.55%). Lauric acid in sn-2 from VCO and PKO showed that the distribution of lauric acid in sn-2 position was not different,48.33and 48.59%. Keywords: virgin coconut oil, palm kernel oil, composition of fatty acids, sn-2 position, lauric acids

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Formulation of Essential Oils as Mosquito Repellent

Journal Of Tropical Pharmacy And Chemistry ◽

10.25026/jtpc.v5i2.231 ◽

2020 ◽

Vol 5 (2) ◽

pp. 71-79

Author(s):

Dwi Setyaningsih ◽

Fitriana Roselly ◽

Neli Muna

Keyword(s):

Refractive Index ◽

Essential Oil ◽

Essential Oils ◽

Coconut Oil ◽

Insect Repellent ◽

Mosquito Repellent ◽

Virgin Coconut Oil ◽

Chemical Substances ◽

Complex Chemical ◽

Color Density

Essential oil has complex chemical substances with a lot of benefit, one of them is as mosquitoe or insect repellent. This research aims to find out the best essential oil formula for mosquito repellent. Essential oils that used in this research are citronella, lemongrass, cajeput, and lavender oil. Essential oils are characterized by its color, density, refractive index, and solubility in alcohol. The essential oil colors met the SNI which was pale yellow to clear yellow, the density was 0.8125 - 0.9114 g/ml, the refractive index was 1.4568-1.4665 and soluble in alcohol. The essential oil mixture resulted in 7 series of formula, namely series A1-A5, B1-B5, C1-C5, D1-D5, E1-E5, F1-F5, and G1-G5. The organoleptic test performed on all formula showed that the preferred formula was the formula E3, G3, and F3. All preferred formula were carried out repellent tests against mosquitoes to determine the effectiveness of the oil mixture in Virgin Coconut Oil (VCO) carrier. The result showed that E3 was more effective repellent compare to F3 and G3 formulas, because it has protection value more than 90% until fourth-hour.

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