scholarly journals Effect of colistin and tylosin used as feed additives on the performance, diarrhea incidence, and immune response of nursery pigs

2016 ◽  
Vol 37 (4) ◽  
pp. 1947 ◽  
Author(s):  
Kelly Mazutti ◽  
Leandro Batista Costa ◽  
Lígia Valéria Nascimento ◽  
Tobias Fernandes Filho ◽  
Breno Castello Branco Beirão ◽  
...  
Keyword(s):  
Immune Response ◽  
Feed Intake ◽  
Immune Cell ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Feed Additives ◽  
Control Group ◽  
Feed Conversion ◽  
Nursery Pigs ◽  
Diarrhea Incidence

For the last several decades, antimicrobial compounds have been used as feed additives to promote piglet growth at weaning, through the prevention of subclinical and clinical disease. However, few studies have assessed the influence of these antibiotics on the immune response of nursery pigs, as well as the relation between performance, health, and immunity of animals that receive feed additives. Therefore, the present study aimed to evaluate the effects of colistin and tylosin when used as feed additives on the performance, incidence of diarrhea, and immune response of nursery pigs. In this study, 72 weaned pigs (average age, 28 days) were allotted into one of three treatment groups: a control group (feed with no antibiotics), tylosin group (feed containing 22 ppm tylosin), and colistin group (feed containing 20 ppm colistin). Weekly, during a five week period, the average daily feed intake, average daily gain, and feed conversion ratio of the pigs were evaluated. Stools were scored daily, in accordance with a fecal texture scale. Blood samples were collected on the day of housing (d0) and on d7, d21, d28, and d35 for immune cell phenotyping. The results of this study showed that piglets in both the colistin and tylosin groups exhibited a significantly higher average daily feed intake, resulting in a higher body weight at the end of the experimental period (d35) when compared with piglets from the control group. Colistin and tylosin also significantly reduced the incidence of diarrhea. Colistin and tylosin modulated the piglets’ immune responses, particularly on d28, by changing the percentage of circulating B lymphocytes, CD4+CD8+ T cells, and the CD4:CD8 ratio.

scholarly journals Influence of phytogenic feed additives and prebiotic in vegetable protein based diet on broiler performance

2018 ◽  
Vol 28 (4) ◽  
pp. 323-330 ◽  
Author(s):  
HR Tanzim ◽  
GB Das ◽  
M Ahmad ◽  
M Barua ◽  
K Islam
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Feed Intake ◽  
Vegetable Protein ◽  
Experimental Period ◽  
Feed Additives ◽  
Feed Additive ◽  
Control Group ◽  
Feed Conversion ◽  
Broiler Performance

This study was conducted to determine the effect of phytogenic feed additive and prebiotic on vegetable protein base diet in broiler performance.  A total of 90 chicks (Cobb-500) were weighted and randomly assigned to the three treatment groups (To, T1 and T2) and supplemented with either phytogenic feed additives or prebiotic and reared for 28 days. Data on live body weight, body weight gain, feed intake and feed conversion (FC) were taken at weekly interval. Results revealed that significant (P<0.05) increase in live body weight of broilers was evident in both phytogenic feed additive and prebiotic supplemented groups comparing to the control group at 4th weeks of age. No significant (P>0.05) differences were found in live weight gain among the treatment groups on weekly intervals along the whole experimental period. However, significant differences (P<0.05) were evident on cumulative weight gain at 3rd and 4th weeks of age. In case of feed intake at the age of 3rd and 4th weeks, significant (P<0.05) differences were obtained with decreased feed intake in both phytogenic feed additive and prebiotic supplemented groups comparing to the control group. In case of feed conversion (FC), there were significant (P<0.05) differences among the groups on 1st week and 4th week of age. Best FC was accounted for prebiotic supplemented group along the whole experimental period. The survivability rates were 96.67%, 100% and 100% in control group, phytogenic feed additive and prebiotic supplemented group respectively. Results finally showed that vegetable protein when supplemented with phytogenic prebiotic feed additives and prebiotic c an additive beneficial effect on performance of when compared to non-supplemented control diet. So, ration using vegetable protein mixed with phytogenic feed additives or prebiotic can be recommended for broiler.Progressive Agriculture 28 (4): 323-330, 2017

scholarly journals INFLUENCE OF ARSIL FEED ADDITIVE ON HEMATOLOGICAL INDICES, PRODUCTIVITY AND STRUCTURE OF INTERNAL ORGANS BROILER CHICKENS

2020 ◽  
Vol 21 (1) ◽  
pp. 65-72
Author(s):  
M. I. Zhyla ◽  
G. M. Mykhalus ◽  
O. A. Maksymovych ◽  
O. V. Lapin ◽  
O. V. Mykhalyuk ◽  
...  
Keyword(s):  
Broiler Chicken ◽  
Average Daily Gain ◽  
Feed Additives ◽  
Biologically Active ◽  
Feed Additive ◽  
Control Group ◽  
Feed Conversion ◽  
Internal Organs ◽  
Hematological Indices ◽  
Group I

Poultry farming using modern technologies requires the employment of veterinary preparation for the prevention of infectious diseases and also feed additives for the improvement of metabolic functions and correction of body resistance. The article presents the results of clinical trials of feed additives in the form of an ionic solution concentrate of the biologically active nanosilicon "Arsil". The clinical study was performed on healthy ten-day-old broiler chicken, cross "Cobb-500", organized into three groups of 20 heads each: Group I received a feed additive at a dose of 0.5 ml per 1 liter of water, group II – at a dose of 1.0 ml per 1 liter of water and group III was the control group (on a regular diet, without feed additives). The use of the studied feed additive was carried out by watering with water for 30 days. Poultry of all groups were fed with identical feeds in accordance with regulatory requirements taking into account the age of the bird. The clinical condition of the bird was monitored daily, control weightings were performed once a week and blood samples were taken for laboratory tests on days 15 and 35 of the experiment. At the end of the experiment, a diagnostic slaughter of birds of all groups and a complete pathological autopsy with selection of material for histological examination were performed. Studies have shown that the use of the feed additive "Arsil" contributed to weight gain and average daily gain, improved the feed conversion and the tendency for the growth of the concentration of hemoglobin, hematocrit and erythrocytes in broiler chicken from the experimental groups compared with the control group at the end of fattening. The structure of the internal organs of birds of all studied groups is preserved, macroscopic changes in organs and tissues are not detected. An increase in the coefficients of mass of immune-competent organs in broiler chicken fed the feed additive "Arsil" compared with the control group was found.

scholarly journals Growth performance and antioxidant status of growing rabbits fed on diets supplemented with Eucommia ulmoides leaves

2018 ◽  
Vol 26 (1) ◽  
pp. 35 ◽  
Author(s):  
Song Li ◽  
Miaoqing Zhao ◽  
Tingting Jiang ◽  
Wenwen Lv ◽  
Shujuan Gao ◽  
...  
Keyword(s):  
Growth Performance ◽  
Feed Intake ◽  
Antioxidant Status ◽  
Basal Diet ◽  
Experimental Period ◽  
Control Group ◽  
Eucommia Ulmoides ◽  
Feed Conversion ◽  
Diet Control ◽  
And Control

<p>The present study evaluated the effect of dietary <em>Eucommia ulmoides leaves</em> (EUL) on growth performance and antioxidant status of growing rabbits under heat stress condition. Four hundred and fifty weaned New Zealand male rabbits (6 wk old) were randomly divided into 3 equal groups (150 rabbits/group) and fed with a basal diet (control, digestible energy (DE): 15.92 MJ/kg and crude protein (CP): 19.24%) or the basal diet supplemented with 1 or 5 g of EUL/kg of diet (EUL1 and EUL5), in which the same quantity of barley meal was replaced. During the 21 d of experiment (43 to 63 d of age), the temperature and relative humidity of the rabbit house ranged from 27.5 to 32.5°C and from 65 to 73%, respectively. We analysed feed intake, growth performance and antioxidant status of growing rabbits. Compared with the control group, at the end of the experimental period, EUL supplementation significantly reduced the average daily feed intake (92.0, 92.8 and 100.7 g/d for EUL1, EUL5 and control, respectively; P&lt;0.05), improved the feed conversion ratio (3.80, 3.81 and 4.59 for EUL1, EUL5 and control, respectively; P&lt;0.05), increased the activities of glutathione peroxidase (+35.5 and +35.0% in plasma and liver of rabbits in EUL5 vs. control group, respectively; P&lt;0.05) and reduced those of malondialdehyde (–12.0 and –46.0% in plasma and liver of rabbits in EUL5 vs. control group, respectively; P&lt;0.05). These results suggest that inclusion of EUL in the diet of growing rabbits improved the growth performance and antioxidant status in growing rabbits.</p>

scholarly journals EVALUATION OF EFFICIENCY OF APPLICATION OF FEED ADDITIVE ON BROILER CHICKENS

2020 ◽  
Vol 21 (2) ◽  
pp. 90-95
Author(s):  
T. R. Levytskyі
Keyword(s):  
Broiler Chickens ◽  
Hematological Parameters ◽  
Average Daily Gain ◽  
Live Weight ◽  
Feed Additives ◽  
Poultry Meat ◽  
Feed Additive ◽  
Control Group ◽  
Feed Conversion ◽  
Experimental Group

A study of the effectiveness of the use of feed additive Liaform in relation to its effect on the growth and development of broiler chickens. For research, 2 groups of broiler chickens of 55 heads (control and experimental) from 8 days of age were formed on the principle of analogues. Feeding of the control group was carried out with standard complete feed. Feeding of the experimental group was carried out with standard complete feed, in which the feed additive Liaform was added at the rate of 2 g / kg. During the experiment, the general condition of the bird, the safety of the bird, zootechnical and hematological parameters were monitored. It is established that the studied feed additive has a positive effect on the productivity of broiler chickens, improves feed absorption. As a result of the use of feed additive Liaform live weight of broiler chickens in the experimental group was 4.3 % higher compared to the control. The average daily gain of chickens in the experimental group exceeded this figure of chickens in the control group by 4,1 %. The use of feed additives helped to increase feed conversion. The use of Liaform feed increased the protein level in poultry meat

scholarly journals Influence of lecithin emulsifier on the utilisation of nutrients and growth of piglets after weaning

2011 ◽  
Vol 50 (No. 10) ◽  
pp. 459-465 ◽  
Author(s):  
P. Daněk ◽  
A. Paseka ◽  
J. Smola ◽  
J. Ondráček ◽  
R. Bečková ◽  
...  
Keyword(s):  
Crude Protein ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Control Group ◽  
Feed Conversion ◽  
Crude Fibre ◽  
Nitrogen Free Extract ◽  
Daily Gain ◽  
Positive Effect ◽  
Experimental Group

The influence of supplementation of a lecithin emulsifier (0.1%) to the feed mixture for piglets after weaning was studied. 16 piglets in the control group (C &ndash; without lecithin) and 16 piglets in an experimental (E) group were monitored in three replications in a 28-day experimental period. We observed higher digestibility of monitored nutrients in the experimental group (crude fat: C = 66.28 &plusmn; 12.11, E = 69.75 &plusmn; 9.85%, crude protein: C = 78.72 &plusmn; 5.47, E = 82.17 &plusmn; 2.23%, crude fibre: C = 56.70 &plusmn; 12.85, E = 59.10 &plusmn; 12.04%, nitrogen free extract: C&nbsp;=&nbsp;86.67 &plusmn; 3.32, E = 87.75 &plusmn; 3.00%, ash: C = 63.63 &plusmn; 11.59, E = 65.73 &plusmn; 10.35%). Statistically insignificantly higher daily average gain (C = 374.1 &plusmn; 107.0, E = 399.1 &plusmn; 104.7 g) of experimental groups and a lower feed conversion ratio (C = 2.285 &plusmn; 0.416, E = 1.768 &plusmn; 0.048 kg/kg) were found out. It was also confirmed in an additional field experiment (C = 279, E = 312 piglets from birth to 71 days of age) where average daily gain weight was 270 g in control and 290 g in experimental group. The influence of lecithin on the occurrence of haemolytic strains of Escherichia coli was not proved. This experiment confirmed a positive effect of the lecithin emulsifier supplement on the efficiency of piglets. &nbsp;

100 Hybrid Rye May Replace Corn in Diets for Nursery Pigs Without Negatively Affecting Average Daily Gain, but gain:feed May Be Reduced

2021 ◽  
Vol 99 (Supplement_1) ◽  
pp. 51-52
Author(s):  
Molly L McGhee ◽  
Hans H Stein
Keyword(s):  
Feed Intake ◽  
Phase 1 ◽  
Average Daily Gain ◽  
Phase 2 ◽  
Phase 3 ◽  
Nursery Pigs ◽  
Body Weights ◽  
Diarrhea Incidence ◽  
Hybrid Rye ◽  
Daily Gain

Abstract Two experiments were conducted to test the hypothesis that replacing corn with hybrid rye in diets for weanling pig diets will not influence growth performance. In experiment 1, 160 pigs (6.0 ± 0.7 kg) were allotted to 40 pens and 5 treatments (Phase 1 (day 1–7): 0, 3, 6, 9, or 12% hybrid rye; Phase 2 (day 8–21): 0, 5, 11, 16, or 21% hybrid rye; Phase 3 (day 22–34): 0, 15, 30, 45, or 60% hybrid rye). In experiment 2, 128 pigs (5.6 ± 0.5 kg) were allotted to 32 pens and 4 treatments (Phase 1: 0, 8, 16, or 24% hybrid rye; Phase 2: 0, 16, 32, or 48% hybrid rye; Phase 3: 0, 20, 40, or 60% hybrid rye). Individual body weights were recorded at the start and end of each phase, and diarrhea incidence was recorded every other day. Diarrhea incidence was analyzed using proportions with SAS Proc Glimmix, whereas other data were analyzed in SAS Proc Mixed using linear and quadratic contrast statements. In experiment 1, body weights and average daily gain (ADG) did not differ among treatments (Table 1), but in experiment 2, ADG in phase 1 increased (linear, P &lt; 0.05) as rye inclusion increased. In both experiments, overall average daily feed intake increased (experiment 1, quadratic, P &lt; 0.05; experiment 2, linear, P &lt; 0.05) with greater rye inclusion and in both experiments overall gain:feed decreased (quadratic, P &lt; 0.05) as rye replaced corn in diets. Diarrhea incidence decreased (quadratic, P &lt; 0.05) with 6 or 9% rye inclusion in phase 1 of experiment 1, but not experiment 2. To conclude, hybrid rye may replace the majority of corn in diets for nursery pigs without impacting ADG, but gain:feed will be reduced due to greater feed intake.

scholarly journals Evaluation of Sweet Basil Powder Plant (Ocimum basilicum L.) as a Feed Additives, on the Performance of broilerChicks

2013 ◽  
Vol 37 (1) ◽  
pp. 52-58
Author(s):  
Thair Jawad Kadhim Al-Kelabi
Keyword(s):  
Body Weight ◽  
Weight Gain ◽  
Feed Intake ◽  
Basal Diet ◽  
Conversion Ratio ◽  
Feed Additives ◽  
Feed Conversion Ratio ◽  
Control Group ◽  
Feed Conversion ◽  
Sweet Basil

The present study was carried out at the Poultry Farm, College of Veterinary Medicine -Baghdad University, for powder sweet basil plant evaluation as feed additives, and its effect on the performance and health of broiler. Three hundred one day old Hubbard broiler chicks were used in this study. Chicks were weighed and randomly divided into 10 treatments groups, with 2 replicates (15chicks each).These groups were fed with the following rations: The 1st group was fed the basal diet (control group).The 2nd,3rd and 4th groups were fed the basal diet+0.3, 0.4 and 0.5 % basil powder for the first 3 weeks only respectively. At the 5th, 6th and 7th groups were fed the same basal diet +0.3, 0.4 and 0.5 % basil powder for the second 3 weeks respectively. While the 8th, 9th and 10th were fed the same basal diet with 0.3, 0.4 and 0.5 % basil powder along the whole six weeks. The experiment was terminated when birds were 6 weeks old. Weight gain, feed intake and feed conversion ratio were measured at the end of first three weeks and also at the end of the experiment. The results revealed that adding sweet basil powder significantly (P< 0.05) increased live body weight, body weight gain and feed conversion ratio as compared with the control, especially on the level 3%, 4%, 5% of Sweet basil powder addition along the whole period of the experiment and There was a significant (P< 0.05) decrease in total feed intake compared with the control group.

scholarly journals Effects of Weaning Age at 21 and 28 Days on Growth Performance, Intestinal Morphology and Redox Status in Piglets

Animals ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 2169
Author(s):  
Dongxu Ming ◽  
Wenhui Wang ◽  
Caiyun Huang ◽  
Zijie Wang ◽  
Chenyu Shi ◽  
...  
Keyword(s):  
Growth Performance ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Redox Status ◽  
Intestinal Morphology ◽  
Feed Conversion ◽  
Study Objective ◽  
Entire Experimental Period ◽  
Diarrhea Incidence ◽  
Better Than

The study objective was to assess effects of different weaning ages on growth performance, intestinal morphology and redox status in Duroc × Landrace × Large White piglets (n = 96) fed diets without antibiotic growth promoters. Piglets were selected from 24 litters based on similar body weight at 14 d of age. All piglets were allocated to two groups in a completely random design with six replicates and eight pigs per replicate (four barrows and four gilts), which were weaned at 21 (n = 48; BW = 6.87 ± 0.33 kg) and 28 (n = 48; BW = 8.49 ± 0.41 kg) days of age. After weaning, pigs were fed a corn–soybean meal-based diet. Average daily gain (ADG), average daily feed intake (ADFI), feed conversion (F:G), diarrhea incidence, gastrointestinal pH, intestinal morphology and redox status were determined. Pigs weaned at 28 d displayed increased ADG from d 8 to 14 (p < 0.01) compared with pigs weaned at 21 d. Pigs weaned at 28 d had a higher ADFI from d 0 to 7 (p < 0.01), d 8 to 14 (p < 0.01), d 15 to 28 (p < 0.05) and during the entire experimental period (p < 0.01) compared with pigs weaned at 21 d. Pigs weaned at 21 d had an improved F:G from d 15 to 28 (p < 0.05) compared with pigs weaned at 28 d. Pigs weaned at 28 d had decreased diarrhea incidence from d 8 to 14 (p < 0.01) and the entire experimental period (p < 0.01) compared with pigs weaned at 21 d. On d 28, the pH of the stomach contents in pigs weaned at 21 d was significantly higher compared with pigs weaned at 28 d (p < 0.01). On d 14, the morphology of the duodenum, jejunum and ileum in pigs weaned at 28 d was improved compared with pigs weaned at 21 d. During the experiment period, the antioxidant abilities of pigs weaned at 28 d of the heart, liver, kidney, intestinal and serum were better than pigs weaned at 21 d. In conclusion, intestinal morphology, pH of the stomach and antioxidant status of pigs weaned at 28 d were better than pigs weaned at 21 d. These factors supported better growth performance and decreased diarrhea incidence.

EFFECTS OF SODIUM BARBITAL ADMINISTRATION ON PERFORMANCE AND RATION DIGESTIBILITY OF YOUNG RUMINANTS

1988 ◽  
Vol 68 (4) ◽  
pp. 1187-1194
Author(s):  
J. R. SEOANE ◽  
J. VIRCHEZ ◽  
A.-M. CHRISTEN
Keyword(s):  
Oral Administration ◽  
Feed Intake ◽  
Dry Matter ◽  
Average Daily Gain ◽  
Feed Additives ◽  
Feed Conversion ◽  
Direct Stimulation ◽  
Sodium Barbital ◽  
Daily Gain ◽  
Better Than

In a first experiment, nine lambs and nine kids newly born were used to study the effect of oral administration of sodium barbital (SB) on performance during weaning. All animals received three doses of SB (0,30 and 60 mg d−1) during weaning and 3 wk postweaning. During the 7-day weaning period, total dry matter intake (TDMI), in terms of percentage of body weight, was higher for animals receiving 30 or 60 mg of SB as compared to controls (P < 0.01). Average daily gain (ADG) of animals receiving SB was twice that of controls (P < 0.01), lambs performing better than kids (228 vs. 119 g, respectively, P < 0.01). Average feed conversion (FC) was also better for lambs than for kids (0.98 vs. 1.54 respectively, P < 0.01). After weaning, TDMI was higher in animals receiving SB (P < 0.03), with no differences observed between doses and species; however, treatment effects were apparent mainly during the first week and disappeared gradually afterwards. During the first week postweaning, ADG and FC were superior for animals receiving SB (P < 0.01 and P < 0.05, respectively). During this period, ADG of lambs was 78% higher than that of kids (P < 0.01). Apparent digestibilities of dry matter, crude protein and lipids were similar for all treatments and species. In a second experiment, eight lambs and eight kids were used to determine if oral administration of SB stimulates feed intake of growing ruminants. Lambs (30–45 kg) received 0, 120 or 160 mg of SB and kids (20–28 kg) were given 0, 80 or 100 mg of SB daily. Feed intake of lambs was not affected by administration of SB. Kids, however, ingested higher amounts of concentrate during the first 3 h after administration of 80 mg of SB. Daily feed intake was not affected. It appears that polyphagic-type drugs can be used effectively as feed additives during weaning to improve animal performance. The effect seems to be by a direct stimulation of feed intake without affecting ration digestibility. Key words: Barbiturate feeding, lambs, kids, polyphagia.

scholarly journals PSVI-18 The use of Spirulina in piglet’s diets: effects on growth performance, selected biochemical blood parameters and small intestine mucosa morphology and metabolomics profiles

2019 ◽  
Vol 97 (Supplement_3) ◽  
pp. 469-470
Author(s):  
Cátia F Martins ◽  
Manolis Matzapetakis ◽  
David D Ribeiro ◽  
Mário Pinho ◽  
João Pedro Bengala Freire ◽  
...  
Keyword(s):  
Small Intestine ◽  
Plasma Cholesterol ◽  
Energy Levels ◽  
Average Daily Gain ◽  
Experimental Period ◽  
Intestinal Morphology ◽  
Control Group ◽  
Feed Conversion ◽  
Plasma Parameters ◽  
Metabolomics Data

Abstract Pig production relies on expensive imported protein feedstuffs namely soybean meal. It is very important to use less conventional feedstuffs such as microalgae. Spirulina has been used in pig feeds as an additive (inclusion levels below 1%). Recently, its use as a protein feedstuff has been proposed. In order to study the effect of Spirulina on growth, intestinal mucosa morphology microscopy, plasma profiles and small intestine and liver metabolomics (1H NMR) of weaned 12 kg piglets, an experiment with 40 male animals was carried out. Animals were divided into 4 groups of 10 animals (Control, 10% Spirulina, 10% Spirulina + Rovabio® and 10% Spirulina + Lysozyme). Piglets were fed ad libitum. All diets had the same protein and energy levels. Piglets were weighed weekly; experimental period was 4 weeks. Animals were sacrificed and blood, liver and small intestine sampled. Variance analysis was used to test diet effect on growth, intestinal morphology and plasma parameters. Metabolomics data were analysed using PCA and PLS-DA. For the same feed intake, the average daily gain was reduced by 14% and feed-conversion ratio increased by 10% in the three diets with Spirulina in comparison to Control. No significant differences (P &gt; 0.05) were found for microvilli height and width or crypt depth. Plasma cholesterol, total lipids and liver aminotransferases (ALT, AST) and alkaline phosphatase (ALP) concentrations were higher in animals fed on Spirulina diets. Metabolic profiles for the two tissues were similar for the four groups, although PLS-DA analysis showed a tendency for the three Spirulina diets to cluster together, separately from the control group. Betaine and glycerol-3-phosphocholine were the most discriminant metabolites. In conclusion, although Spirulina had no significant effects on small intestinal morphology and metabolomics profiles, its use for piglet feeding in incorporation levels of 10% leads to losses in growth performances.

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