Biosimilars in Brazil: developments in 2015 and business perspectives

2015 ◽  
Vol 21 (4) ◽  
Author(s):  
Denise Golgher ◽  
Roberto Rodrigues ◽  
Rodrigo Couto Massafera

Brazil is looking into foreign technology to foster innovation in the country’s industrial health complex. Biological plants are being built and partnerships with multinationals have been established with the goal to in license technology, manufacture and supply the population with biosimilars made in Brazil. This article brings up-to-date information on the biosimilar market in the country, with information on the public-private partnerships and regulatory approvals. With two biosimilars approved in 2015 and the ongoing development regarding the local pharmaceutical companies, there is a good window of opportunity to create new businesses in the soon to be 4th pharmaceutical spender in the world. 

2021 ◽  
Author(s):  
◽  
Amy Hill

<p>This paper explores one very important issue in the regulatory regime for medicines in New Zealand and around the world- the deficit of information about medicines available to doctors, patients and independent researchers. Much of the information about safety, efficacy and quality of drugs is held and controlled by pharmaceutical companies and regulators. The public is entitled to this information in full.</p>


Author(s):  
Britta Ricker ◽  
Menno-Jan Kraak ◽  
Yuri Engelhardt

Maps are representations of the world. They offer summaries or simplifications of data that are collected, attempt to reveal unknowns, to simplify and communicate complex spatial phenomena. Numerous decisions are made in the process of creating a map. Seemingly inconsequential variations of cartographic design decisions offer many ways to illustrate this process. We use an open dataset related to the United Nations Gender Inequality Index to demonstrate design decision points and their output. As governments are increasingly making data open to the public, and map-making tools and software are now more accessible online, these considerations are important both for those making and reading maps online.


Water Policy ◽  
2018 ◽  
Vol 20 (6) ◽  
pp. 1145-1160 ◽  
Author(s):  
Thomas Edson Espíndola Gonçalo ◽  
Danielle Costa Morais

AbstractThe world is facing a growing water scarcity problem in the most diverse regions. The Rio Grande do Norte (RN), a Brazilian semi-arid region, is facing its severest drought in the last 100 years. Given this context, managing water resources and combating the effects of the drought have become even more important. Decisions made in this context may involve multiple criteria established by more than one decision-maker. To tackle this issue, a multicriteria model for group decisions is proposed in order to rank the municipalities of the region and thus guide the public administration's efforts in tackling the drought and mitigating its effects. The applicability of the model is exemplified by studying the Apodi-Mossoró river basin, for which the PROMETHEE GDSS method was selected and the preferences of three decision-makers were calculated.


2021 ◽  
Vol 9 (1) ◽  
pp. 41
Author(s):  
George Nwangwu

Nigeria, like most countries around the world, has turned to Public-Private Partnerships (PPPs) to finance its infrastructure deficit. However, it appears that the government of Nigeria looks towards PPPs as the major solution to the country’s infrastructure crisis. In a sense PPPs are being sold to the public as if they were free, that the private sector would come in with its funds, provide the desired services and that the problem with the country’s infrastructure would automatically cease. This paper argues that this supposition is a myth and that the role of PPPs in the provision of public infrastructure is more nuanced than is being bandied around. PPPs are not the panacea to all of the country’s infrastructure problems and also are far from being completely free. It is however the case that if appropriately deployed, in most cases PPPs provide some advantages over conventional public sector procurements. This paper explores the different advantages and disadvantages of PPPs and suggests ways in which PPPs may be effectively used to improve the country’s infrastructure with reduced fiscal exposure to government.


2020 ◽  
Vol 10 (1) ◽  
pp. 27
Author(s):  
I Nyoman Suka Ardiyasa

The island of Bali is an island very vulnerable to disaster, it is proven with historical records that Bali has experienced a major earthquake better known as <em>Gejer Bali</em>. Various efforts have been made by the community from the past until now in the effort of mitigation done in <em>sekala </em>and <em>niskala</em>.   In the community, people believe that if they want to avoid the disaster then the community must implement the <em>tri hita karana</em>, while <em>niskala </em>(theologically) done with various <em>upakara</em>. <em>Upakara </em>sources and the types of disasters that occur in this world are believed to be contained in the <em>Lontar Roga Sanghara Bhumi </em>manuscript. But the existence of the manuscript is not much to know so it is necessary to conduct a more in-depth review so that it can be disseminated to the public. To focus on these reviews, we focused on three problem formulas: analyzing the summary of the <em>Roga Sanghara Bhumi lontar </em>manuscripts, the types of disasters mentioned in the <em>Roga Sanghara Bhumi lontar</em>, <p>and the theological attempts made in dealing with the disasters mentioned in <em>lontar Roga Sanghara Bhumi</em>.</p>From the results of the study conducted it is briefly known that the <em>lontar Roga Sanghara Bhumi </em>contains about the causes of catastrophe or disaster occurred in the world, the types of catastrophes or disasters that can occur in the world and some characteristics of the coming disaster or disaster, while the types The disaster mentioned in the lontar of <em>Roga Sanghara Bhumi </em>is a type of disaster that repeats every <em>sasih </em>it and the kind of disaster that occurs which is seen from the bad gesture, in the concept of <em>Lontar Roga Sanghara Bhumi </em>called <em>Durmanggala</em>. The theological efforts undertaken in tackling the disasters mentioned in the <em>lontar </em>of <em>Roga Sanghara Bhumi </em>are performing ceremonies that are shown to <em>Ida Sang Hyang Widhi Wasa </em>with the aim of pleading for salvation such as <em>Prayascita </em>Ceremony, Master <em>Piduka</em>, <em>Labuh Gentuh, Jagat, Pamahayu Bumi </em>and <em>Nangluk Mrana. </em>All these ceremonies are theological (mitigation) efforts in reducing disaster risks that occur on earth.


2005 ◽  
Vol 25 (2) ◽  
pp. 219-240 ◽  
Author(s):  
CHRIS LONSDALE

This article discusses the concept of contractual uncertainty and assesses its impact upon the ability of public sector bodies to obtain value for money from their suppliers. Particularly in the realm of public private partnerships, governments around the world are increasingly developing specifications that are likely to be subject to contractual uncertainty. Contractual uncertainty is not necessarily a problem in itself, but can be if the public body cannot avoid an unfavourable power relation in its dealings with the supplier, because it is in a poor position to undertake the inevitable post-contractual negotiations. The argument is illustrated with two cases from the UK public sector that highlight the fact that British public bodies are often seeking to manage contractual uncertainty from a position of weakness.


2004 ◽  
Vol 70 (2) ◽  
pp. 199-215 ◽  
Author(s):  
Tony Bovaird

This article explores the current state of knowledge in relation to public–private partnerships (PPPs), taken to mean working arrangements based on a mutual commitment (over and above that implied in any contract) between a public sector organization with any organization outside of the public sector. Since it originally became fashionable over 25 years ago, the concept of PPPs has been strongly contested. However, PPPs are now to be found in the public domain in many countries around the world and their number has been increasing in recent years. This article looks at how this has happened, what have been the strengths and weaknesses of this development and what the future may hold for PPPs. It argues that we are still at an early stage of learning which types of PPP are appropriate for which tasks and at managing PPPs to increase public value. It will be essential to apply principles of good governance to the future development of PPPs — but it will also be necessary to ensure that these principles are genuinely appropriate to the context in which these PPPs are working.


2021 ◽  
Vol 5 (1) ◽  
pp. 34
Author(s):  
Siti Khurriyatunnisa Rahayu ◽  
Katiah Katiah

Luntur Kasumba (Red-naped Trogon) is a species of bird belonging to the order Trogonidae with the scientific name Harpactes Kasumba which is scattered in the tropical lowland forests of the Great Sunda namely Sumatera, Java, and Kalimantan at an altitude of less than 600 meters above sea level. The source of ideas for making fashion products which are then examined and made in the form of this article comes from the Luntur Kasumba bird which is transformed into a stilation motif and the stylation motif that has been made is applied to textiles using digital printing techniques. The purpose of making articles from the results of the analysis of this fashion product is to elevate the beauty of the Luntur Kasumba bird which is applied to the world of fashion and informed the public in making ready-to-wear clothing, which is further analyzed from the scientific side of the fashion field. The benefit of designing this work is to enhance and develop the writer's creativity in designing fashion by applying the bird stylation of Luntur Kasumba using digital printing techniques and making articles from the analysis of fashion products. The method used in writing the results of the analysis of this fashion product research is Practic-Led Research, which is intended to practice the stapling technique of the Kasunt Luntur bird motif, applying the design of the stylation motif to textiles using digital printing techniques, and is realized in the form of clothing with the addition of fringes as decorative trims. Ready to-Wear clothing made with digital printing techniques with the stylized motif of the Kasumba faded bird is an innovation in preserving the bird species of Indonesia's natural wealth into the world of Fashion. Keywords: Stilation, Luntur Kasumba Bird, Ready to-Wear, Fringes Abstrak Luntur Kasumba (Red-naped Trogon) adalah jenis burung yang tergolong  kedalam ordo Trogonidae dengan nama ilmiah Harpactes Kasumba yang tersebar di hutan dataran rendah tropis Sunda Besar yaitu Sumatera, Jawa, dan Kalimantan pada ketinggian kurang dari 600 meter dari permukaan laut. Sumber ide pembuatan produk busana yang kemudian diteliti dan dibuat dalam bentuk artikel ini berasal dari burung Luntur Kasumba yang diwujudkan menjadi motif stilasi dan motif stilasi yang telah dibuat diaplikasikan pada tekstil menggunakan teknik digital printing. Tujuan pembuatan artikel dari hasil analisis produk busana ini adalah untuk mengangkat keindahan burung Luntur Kasumba yang diterapkan pada dunia fashion dan diinformasikan kepada masyarakat pada pembuatan busana ready to-wear, yang selanjutkan di analisis dari sisi keilmuan bidang busana. Manfaat perancangan karya ini adalah untuk meningkatkan dan mengembangkan kreativitas penulis dalam merancang busana dengan menerapkan stilasi burung Luntur Kasumba mengguanakan teknik digital printing dan membuat artikel dari hasil analisis produk busana. Metode yang digunakan dalam penulisan hasil analisis  dari penelitian produk busana ini yaitu Practic-Led Research, yang dimaksudkan untuk mempraktikan teknik stilasi motif burung Luntur Kasumba, mengaplikasikan desain motif stilasi tersebut pada tekstil menggunakan teknik digital printing, dan diwujudkan dalam bentuk busana dengan penambahan fringes sebagai decorative trims. Busana Ready to-Wear yang dibuat dengan Teknik digital printing dengan motif stilasi burung luntur kasumba merupakan suatu inovasi di dalam melestarikan jenis burung kekayaan alam Indonesia ke dalam dunia Fashion.   Kata Kunci: Stilasi, Burung Luntur Kasumba, Ready to-Wear, Fringes


Philologia ◽  
2021 ◽  
pp. 103-110
Author(s):  
Livia Caruntu-Caraman ◽  

In contemporaneity, the English language successfully fulfills the role of a mediator in international communication, deeply influencing the other languages, including Romanian. Through the realities of the brand made in the Anglo-American space, which are propagating inventively in all four parts of the world, penetrate in the local vocabulary and their names, being assimilated and used in internal daily expression. The given words, called Anglicisms, cause inaccuracies among both users and researchers. In order to solve some of the problems, we propose the design of a small dictionary, in which to collect all the recent Anglicisms from our use in order to be subjected, from scholarly positions, to a regulated interpretation that will become an obligatory norm to follow. The language consumer should consult here spelling and morphological values, pronunciation and stress, decoding of abbreviations and etymology, semantic definitions and practical examples. Finally, the Anglicisms, which have previously confused the speaker, to be scientifically processed, elucidated and returned to the public.


2021 ◽  
Author(s):  
◽  
Amy Hill

<p>This paper explores one very important issue in the regulatory regime for medicines in New Zealand and around the world- the deficit of information about medicines available to doctors, patients and independent researchers. Much of the information about safety, efficacy and quality of drugs is held and controlled by pharmaceutical companies and regulators. The public is entitled to this information in full.</p>


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