Nutritional Content, Phytochemical Evaluation and Antipyretic Effect of Methanol Leaf Extract of Senna siamea (Kassod tree)

Red spinach (Alternanthera amoena) is one of the vegetable commodities that many people in demand for consumption because of its high nutritional content. Efforts to increase the production of red spinach often experience various obstacles. The main obstacle that limits the productivity of red spinach in the tropics is the number of Plant Disturbing Organisms in the form of pests and potential diseases that can attack and decrease the production of spinach. One of the pests that often attack spinach is the existence of army worm (Spodoptera litura F.). Therefore, farmers need a way to eradicate the pest. This research is experimental using Random Complete Group. The data obtained were analyzed with variant analysis (ANOVA) in one direction and continued with LSD (Least Significant Different) test. Provision of botanical insecticide done by spraying the extract of leaves and seeds mimba with concentration dose 0%, 5%, 10% and 15%. In the final analysis of mortality data of army worm (Spodoptera litura F.) treated with mimba leaf extract obtained significant value of 76.263 at a significant level of 0.05 so it can be concluded that there is influence of mimba leaf extract on mortality of army worm. In the final analysis of mortality data of army worm (Spodoptera litura F.) treated with mimba seed extract obtained significant value of 78.625 at a significant level of 0.05 so it can be concluded that there is an effect of mimba seeds extract on mortality army worm. Keywords: mimba leaf extract, mimba seed extract, red spinach (Alternanthera amoena), army worm (Spodoptera litura F.), botanical insecticide

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EVALUATION OF ANTI-INFLAMMATORY, ANALGESIC, ANTIPYRETIC EFFECT OF EICOSANE, PENTADECANE, OCTACOSANE, AND HENEICOSANE

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2020.v13i4.36196 ◽

2020 ◽

pp. 29-35

Author(s):

PATRICK NWABUEZE OKECHUKWU

Keyword(s):

Acetic Acid ◽

Bioactive Compounds ◽

Leaf Extract ◽

Morphological Changes ◽

Gas Chromatography Mass Spectrometry ◽

Brewer’S Yeast ◽

Antipyretic Effect ◽

Brewer's Yeast ◽

Dependent Inhibition ◽

Anti Inflammatory

Objective: Marantodes pumilum (MP) is a plant widely used in traditional medicine in the Southeast Asian region and been reported to possess anti-inflammatory, analgesic, antipyretic, and antiulcer properties. The aim of the study is to identify the bioactive phytochemicals present in the purified leaf extract of MP using gas chromatography mass spectrometry (GC-MS), and to determine their anti-inflammatory, analgesic, and antipyretic effect in a rat model. Methods: A dichloromethane crude extract of MP was partially purified using column chromatography, and the bioactive compounds were identified using GC-MS. The anti-inflammatory, analgesic, and antipyretic activities of the identified bioactive compounds were evaluated using formalin, carrageenan, acetic acid, and brewer’s yeast to induce the rats. Results: Eicosane, pentadecane, octacosane, and heneicosane were identified as bioactive compounds in purified leaf extract of MP. These bioactive compounds did not show any toxicity on the rats at 1000 mg/kg. There was no mortality, and no apparent behavioral, physiological, and morphological changes of the internal organs occurred. They exhibited a very significant (p<0.05) dose-dependent inhibition of acetic acid-induced writhing, formalin-induced paw licking, carrageenan-induced paw edema, and brewer’s yeast-induced pyrexia. Conclusions: Eicosane and pentadecane were able to show very strong anti-inflammatory, analgesic, and antipyretic effects. The observed effects of the bioactive compounds are similar to previous reports on crude and partially purified leaf extract of MP. The finding suggests that eicosane and pentadecane maybe the major bioactive compounds present in the purified leaf extract of MP.

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Antipyretic effect of key lime (Citrus aurantiifolium) leaf extract on white rats

Biofarmasi Journal of Natural Product Biochemistry ◽

10.13057/biofar/f100201 ◽

2012 ◽

Vol 10 (2) ◽

pp. 35-39

Author(s):

AMELIA KARTIKA WIDOWATI ◽

NUR HAFIDHA HIKMAYANI ◽

ETI PONCORINI PAMUNGKASARI

Keyword(s):

Body Weight ◽

Leaf Extract ◽

Negative Control Group ◽

Positive Control ◽

Negative Control ◽

Control Group ◽

Antipyretic Effect ◽

White Rats ◽

Key Lime ◽

One Way Anova

Widowati AK, Hikmayani NH, Pamungkasari EP. 2012. Antipyretic effect of key lime (Citrus aurantifolia) leaf extract on white rats. Biofarmasi 10: 35-39. The objective of this study was to evaluate the antipyretic effect of key lime (Citrus aurantifolia L.) leaf extract on white rats (Rattus norvegicus) induced fever by using DPT vaccine. Thirty male white rats with the body weight of Â±200 grams and the age of 2-3 months old were used in this study. Those rats were grouped equally into five groups, consisted of a negative control group (2 mL aquabidest), a positive control group (acetaminophen 6.3 mg/100 g of body weight), the first dose of key lime leaf extract (1.26 mg/100 g of body weight), the second dose (2.52 mg/100 g of body weight) and the third dose (5.04 mg/100 g of body weight). The measurement of rat temperature was conducted before and 2 hours after getting DPT vaccine, and every 30 minutes posttreatment until 120 minutes. Data at the 120th minute were analyzed by using One-Way Anova test. The results of One-Way Anova test showed that there were significant differences (p<0.05) among treatment groups. The results of post-hoc test analysis showed that the significant differences (p<0.05) were found between a negative control group and four other groups. There was no significant difference (p>0.05) between a positive control group and three groups of key lime leaf extract. It concluded that the key lime leaf extract has an antipyretic effect on white male rats.

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Pengaruh Konsentrasi Ekstrak Daun Sirsak Terhadap Penurunan Kualitas Telur Ayam Ras Selama Penyimpanan

Jurnal Mutu Pangan : Indonesian Journal of Food Quality ◽

10.29244/jmpi.2020.7.2.85 ◽

2020 ◽

Vol 7 (2) ◽

pp. 85-89

Author(s):

Isye Jean Liur

Keyword(s):

Leaf Extract ◽

Egg Quality ◽

Egg Yolk ◽

Nutritional Content ◽

Randomized Design ◽

Two Factors ◽

Completely Randomized Design ◽

Chicken Eggs ◽

Haugh Unit

Hen egg is easy to get and affordable. Besides having a complete nutritional content, chicken eggs are also easily damaged due to microbial activity during storage so that it can reduce egg quality. Therefore, a preservation process is needed to maintain egg quality. This study aims to determine the effect of soursop leaf extract concentrations on decreasing the quality of eggs. This research used a completely randomized design with two factors, the first factor was the concentration of soursop leaf extract (20, 30, 40%) and the second was the shelf life (0, 7, 14, 21 and 28 days). Observation included egg white index, egg yolk index, haugh unit, and weights of eggs. The results indicate that eggs with soursop leaf extract immersion treatment can maintain egg quality. The concentration of soursop leaf extract as much as 40% gives better results in maintaining the quality of eggs.

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PENAMBAHAN EKSTRAK DAUN KEMANGI DAN LAMA PERENDAMAN TERHADAP MUTU DAN DAYA AWET IKAN NILA (Oreachromis niloticus) SEGAR

Biopendix: Jurnal Biologi, Pendidikan dan Terapan ◽

10.30598/biopendixvol6issue1page7-11 ◽

2020 ◽

Vol 6 (1) ◽

pp. 7-11

Author(s):

Enjel Souhoka ◽

Alwi Smith ◽

Ine Airini

Keyword(s):

Antibacterial Activity ◽

Shallow Water ◽

Freshwater Fish ◽

Leaf Extract ◽

Room Temperature ◽

Chemical Activity ◽

Tropical Fish ◽

Nutritional Content ◽

Sensory Test ◽

Pharmacological Testing

Background: Nila is a tropical fish that likes shallow water. Nila has better nutritional content compared to other freshwater fish, but Nila is also a food that is quickly damaged and spoiled. Pharmacological testing shows that basil has antibacterial activity. Basil leaves contain saponins, flavonoids and tannins which have many benefits besides being a spice in cooking it is also beneficial for bodily health. Method: This study immersed Nila in basil leaf extract (30 ml, 60 ml, 90 ml) dissolved in water to a volume of 0.5 liters for 30 minutes. After that it is stored at room temperature for 0 hours, 4 hours and 6 hours. Results: The results of the study using the ANOVA test showed that with the addition of basil leaf extract T1 (30ml), T2 (60 ml) and T3 (90 ml) there was no change in texture, color, odor and eyes on the 4 hour immersion while in the 6 hour immersion there was a change in texture and color. Conclusion: Based on the results and discussion above, it can be concluded that the addition of basil leaf extract to the freshness of Nila can be seen in 4 hours of immersion because, the results obtained are good, there is no change in the texture, color, odor and eye categories based on 4 sensory test scales. This happens because there is no enzyme, microorganism and chemical activity so that the freshness of the fish is maintained.

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The antipyretic effect of basil leaf extract (Ocimi sancti folium) in rats

Biofarmasi Journal of Natural Product Biochemistry ◽

10.13057/biofar/f040204 ◽

2006 ◽

Vol 4 (2) ◽

pp. 65-71

Author(s):

ANDINA WIDIASTUTI ◽

YUL MARIYAH ◽

SUHARSONO SUHARSONO

Keyword(s):

Temperature Measurement ◽

Analysis Of Variance ◽

Rectal Temperature ◽

Leaf Extract ◽

Dose Group ◽

Univariate Analysis ◽

Time Range ◽

Antipyretic Effect ◽

Significant Difference ◽

Post Hoc

Basil leaves are believed by community to reduce the fever. This study aimed to determine the effect of antipyretic and the effectiveness of basil leaf extract (Ocimi sancti folium) in rats. This research was a laboratory experimental research by using a random sampling technique. The experimental animal used was Wistar rats aged less than 2 months, as much as 20 rats divided into 4 groups. Group 1 as a negative control group was given aquadest of 2.5 ml, while groups 2, 3 and 4 as test groups were each given basil extract by 3.15 mg/100 gr BB, 6.30 mg mg/100 gr BB and 12.60 mg/100 gr BB, respectively, dissolved in 2.5 ml of aquadest. To increase the temperature, it was injected vaccine DPT 0.2 cc intra-muscular. The temperature measurement is conducted by using a digital thermometer. The data obtained were analyzed by using Statistical Package for Social Sciences 11.5 (SPSS 11.5) with Univariate Analysis of Variance method followed by Post Hoc test. The result of one factor analysis from Univariate Analysis of Variance test showed that the average of rats rectal temperature was significantly different for each test group and for each time range of temperature measurement, each of them was 0.034 and 0.005 with a significant level (Î±) = 0.05. From the result of analysis by using Post Hoc Test, there was a significant difference between dose group of 3.15 mg/100 gr BB with a dose group of 12.60 mg/100 gr BB and between the time of temperature measurements of 120 minutes and 180 minutes. At first dose and 180th minute, it was obtained a lowest rectal rats temperature. The results showed that the basil leaf extract had an antipyretic effect on rats. The optimal effectiveness evidenced by a lowest average rectal temperature was achieved by a dose of 3.15 mg/100 gr BB at 180th minute.

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