scholarly journals Clinico-mycological Evaluation of Dermatophytes in a Tertiary Care Hospital of Saurashtra, Gujarat, India

2020 ◽  
Author(s):  
Gopee E Makwana ◽  
Manish Mathur
Keyword(s):  
Fungal Infections ◽  
Tertiary Care ◽  
Fungal Growth ◽  
Trichophyton Mentagrophytes ◽  
Personal Hygiene ◽  
Care Hospital ◽  
Humid Climate ◽  
Cross Sectional ◽  
Opportunistic Fungi ◽  
Systemic Involvement

Introduction: Dermatophytes and opportunistic fungi are common skin infection mainly affecting superficial layers of integument with rare systemic involvement. The higher prevalence in India is supposedly due to the hot and humid climatic condition, occupation and low socio-economic status. Recent upsurge in fungal infections are due to increased incidence of immunosuppressive state. Aim: To study the clinical manifestation and mycological evaluation of dermatophytosis. Materials and Methods: The present cross-sectional observational study was conducted during December 2007 to October 2009 in MP Shah Medical College and GG Hospital, Jamnagar, Gujarat, India. Samples were taken from 200 patients with clinically diagnosed dermatophytosis. Depending on the site of lesion, samples from skin, hair or nail were taken. These samples were than examined directly under microscope and cultured on Sabouraud’s Dextrose Agar (SDA) and Cornmeal Agar (CMA). Descriptive statistics like mean and percentages were used to infer results. Results: Out of 200 patients, 177 (88.5%) samples were positive by Potassium Hydroxide (KOH) mount while 127 (63.5%) samples were positive by culture. Most common species of dermatophytes identified was Trichophyton rubrum followed by Trichophyton mentagrophytes. Agricultural workers were found to be more prone to dermatophytic infection and males (61%) were more commonly affected than females (39%). Conclusion: Dermatophytosis is a common superficial mycotic infection in Saurashtra region where hot and humid climate, poor socio-economic condition and compromised personal hygiene play an important role in fungal growth. In the present study, tinea corporis was found to be the most common clinical type with T. rubrum being the commonest isolated species.

Pattern of Dermatoses in a tertiary care hospital in Konkan Region, Maharashtra

2021 ◽  
Vol 7 (4) ◽  
pp. 311-314
Author(s):  
U Ketan Raju ◽  
Hanamant G Bobade ◽  
Anil Mishra
Keyword(s):  
Skin Diseases ◽  
Fungal Infections ◽  
Systemic Disease ◽  
Tertiary Care ◽  
Holistic Approach ◽  
Extensive Study ◽  
Care Hospital ◽  
Age Group ◽  
Humid Climate ◽  
Cross Sectional

Skin diseases can manifest in various ways. Sometimes it can be secondary to underlying systemic disease. In developing countries including India skin diseases are very common but they are being neglected with the thought that they are always benign.Our study is a cross sectional one done to determine the pattern and magnitude of skin diseases. All newly registered patients reporting to Skin OPD of B.K.L.Walawalkar Rural Medical College, Dervan during the period from 1 January 2018 to 31 December 2019 were enlisted in the study. Out of 5090 patients included in our study, ­­52.62% were female patients and 47.38% were males with female to male ratio of 1.11:1. Majority of the patients (21.47%) was from the age group 21-30 years followed by the age group of 11-20 years (19.58%), followed by the age group of 31-40 years (18.52%). Fungal infections constituted the maximum number of the cases (51.53%), followed by Eczema (17.44%). The Acne comprised of (7.19%). Fungal infections comprised majority of cases followed by eczema and allergic disorders in Konkan region of Maharashtra which has a tropical and humid climate. Thus an extensive study may be needed to have a holistic approach to the problem establish a correlation between the variables.

scholarly journals Epidemiological characterization of dermatophytes at a tertiary care hospital in Eastern Uttar Pradesh, India

2019 ◽  
Author(s):  
Ankur Kumar ◽  
Vandana Upadhyay ◽  
Amresh K. Singh ◽  
Jayesh Pandey
Keyword(s):  
Low Socioeconomic Status ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Uttar Pradesh ◽  
Common Species ◽  
Personal Hygiene ◽  
Clinical Samples ◽  
Care Hospital ◽  
Direct Microscopic Examination ◽  
Superficial Mycosis

Background and Purpose: Superficial mycosis is more prevalent in tropical and subtropical countries, such as India. Regarding this, the present study was conducted to determine the epidemiology of superficial mycosis and identify the most common dermatophytic species in this region. Materials and Methods: For the purpose of the study, a total of 220 skin scraping, nail, and hair root specimens were collected. Direct microscopic examination was performed using potassium hydroxide mount. Additionally, the samples were inoculated onto Sabouraud dextrose agar (SDA) and dermatophyte test medium (DTM). The fungal colony of each isolates was stained with lactophenol cotton blue mount, and observed under microscope for species identification. Results: Out of 220 isolates, 172 samples, obtained from 108 males 64 females, were positive for skin fungal infections by either KOH mount or culture. Furthermore, 113 isolates were identified as dermatophytes, while 59 samples were found to be non-dermatophytes. Among the dermatophytes isolated from different clinical samples, Trichophyton verrucosum (42/113, 38%) was the most common species, and Tinea corporis was the most common infection (36.2%). Conclusion: As the findings indicated, dermatophytes had an isolation rate of 78%, which is higher than normal. This can be due to the fact that the majority of the patients were from a rural background (71.7%) with a low socioeconomic status and poor personal hygiene who were exposed to climatic changes.

scholarly journals Clinicomycological evaluation of dermatophytosis at tertiary care hospital in central India

2018 ◽  
Vol 4 (3) ◽  
pp. 409
Author(s):  
Shyam Govind Rathoriya ◽  
Ankit Kumar Jain ◽  
Kavita A. Shinde
Keyword(s):  
Fungal Infections ◽  
Tertiary Care ◽  
Age Groups ◽  
Central India ◽  
Common Species ◽  
Tinea Corporis ◽  
Valuable Insight ◽  
Care Hospital ◽  
Cross Sectional ◽  
Tinea Cruris

<p class="abstract"><strong>Background:</strong> Dermatophytoses are the infection of keratinized tissues such as the epidermis, hair, and nails caused by a group of closely related filamentous fungi known as dermatophytes.</p><p class="abstract"><strong>Methods:</strong> It was a hospital based cross-sectional study. A total number of 150 clinically diagnosed cases of skin, hair and nail infections were randomly selected from all the age groups and of both the sexes, attending Dermatology Outpatient department of CMCH, Bhopal from January 2016-December 2017.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of total 150 subjects, most common clinical type of dermatophytosis, identified in our study, was tinea corporis in 53 (35.3%) subjects followed by tinea cruris in 34 (22.6%) subjects. 134 (89.3%) subjects were tested positive by direct microscopy (KOH mount) and 69 (46.0%) by culture. Highest KOH mount positivity was seen in patient suffering from tinea corporis (94.3%) followed by tinea cruris (94.1%). Culture positivity was highest with tinea corporis (54.7%) followed by tinea lesions on more than one site (47.3%) and tinea cruris (47.0%). In our study, total 69 culture positive samples were isolated and the most common species isolated was T. rubrum in 41 (59.42%) cases.</p><p><strong>Conclusions:</strong> The present study gives valuable insight regarding clinical and mycological pattern of superficial fungal infections in this region as well as shows the importance of mycological examination of dermatophytosis samples for planning effective management. </p>

CLINICO-MYCOLOGICAL PROFILE OF DERMATOPHYTOSIS AND DERMATOMYCOSIS AMONG PATIENTS ATTENDING OUTPATIENT DEPARTMENT IN A TERTIARY CARE HOSPITAL.

2021 ◽  
pp. 1-3
Author(s):  
Kapaganty V Chakradhar ◽  
Dilruba Begum ◽  
Ruby Devi N ◽  
Raya Roja
Keyword(s):  
Tertiary Care ◽  
Fungal Growth ◽  
Trichophyton Mentagrophytes ◽  
Skin Lesions ◽  
Microsporum Gypseum ◽  
Care Hospital ◽  
Female Ratio ◽  
Hair Samples ◽  
Mycological Examination ◽  
Male To Female

This study was conducted to determine the common isolates causing dermatophytosis and other fungi causing dermatomycosis in patients presenting with skin lesions with or without involvement of hair and nails. A total of 75 patients were included in the study with 86 distinctive clinical lesions, of which Tinea corporis (46.7%,) was the most predominant followed by T. cruris (22.7%), T. unguium (14.7%) with a male to female ratio of 1.3:1. KOH mounts were made from samples and examined for fungal elements and samples were sent to Microbiology laboratory for culture, and identication among them 77.3% were skin scrapings alone and 14.7% were nail clippings along with skin scrapings and 8% were hair samples along with skin scrapings. Most common isolate was Trichophyton rubrum (40%) followed by Trichophyton mentagrophytes (17.3%), Trichophyton tonsurans (9.3%), Microsporum gypseum (4%) and no fungal growth was found in 17.3% of the samples. The study signies the importance of mycological examination in the diagnosis of dermatophytosis.

scholarly journals Antifungal susceptibility pattern of dermatomycosis in a tertiary care hospital of North India

2018 ◽  
Vol 4 (2) ◽  
pp. 240
Author(s):  
Ravika K. Budhiraja ◽  
Saurabh Sharma ◽  
Sarbjeet Sharma ◽  
Jasleen Kaur ◽  
Roopam Bassi
Keyword(s):  
Antifungal Agents ◽  
Fungal Infections ◽  
Treatment Options ◽  
Antifungal Susceptibility ◽  
Tertiary Care ◽  
Public Health Problem ◽  
Trichophyton Mentagrophytes ◽  
North India ◽  
Care Hospital ◽  
Microbroth Dilution

<p class="abstract"><strong>Background:</strong> Dermatomycoses affect the outer layers of the skin, nails and hair without tissue invasion and are often caused by dermatophytic molds, candida &amp; non dermatophytic molds. Although not dangerous, they are important as a public health problem particularly in the immunocompromised. There are limited studies on the efficacy of antifungal agents against dermatophytes in North India.</p><p class="abstract"><strong>Methods:</strong> This study was conducted to test the efficacy of 5 systemic antifungal agents viz. voriconazole, itraconazole, terbinafine, fluconazole &amp; griseofulvin using Microbroth dilution technique.<strong></strong></p><p class="abstract"><strong>Results:</strong> Three different species of dermatophytes which were isolated from the clinically suspected cases were <em>Trichophyton mentagrophytes</em>, <em>T. rubrum</em> and <em>M. gypseum</em>. According to the obtained results, Itraconazole and Voriconazole showed the lowest MIC range while Fluconazole and Griseofulvin had the highest MIC range for most fungi tested.</p><p class="abstract"><strong>Conclusions:</strong> Despite several treatment options being available for cutaneous fungal infections, due to an inappropriate response, there is an increasing need for determining an antifungal susceptibility profile for specific fungal strains. This will enable the clinician to select an appropriate antifungal agent with minimal side effects to avoid antifungal resistance and treatment failure.</p>

scholarly journals Status of pulmonary fungal infections among individuals with clinical signs of pulmonary tuberculosis at a University Teaching Hospital in Southwestern Uganda.

2021 ◽  
Author(s):  
Israel Kiiza Njovu ◽  
Benson Musinguzi ◽  
James Mwesigye ◽  
Kennedy Kassaza ◽  
Joseph Turigurwa ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Fungal Infections ◽  
Clinical Signs ◽  
Study Participant ◽  
Fungal Growth ◽  
University Teaching ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Opportunistic Fungi ◽  
Pulmonary Fungal Infections

Abstract Background: Pulmonary mycoses are very important diseases of the respiratory tract and are responsible for significant morbidity and mortality rates worldwide. However less attention has been paid to them. In this study we determined the prevalence of pulmonary mycoses and their aetiological agents among individuals with clinical signs of pulmonary tuberculosis at Mbarara Regional Referral Hospital (MRRH). Method: This was a Laboratory based cross sectional survey in which 113 participants were recruited. Sputum samples were corrected from each study participant. To each sample the following tests were done; Sabouraud Dextrose Agar (SDA) Culture, GeneXpert and Potassium hydroxide (KOH). Fungal growth of filamentous fungi and yeasts were further examined with LPCB and Germ tube respectively. Generated data was analysed using R studio. Results: Out of 113 participants, 80 (70.8%) had pulmonary mycoses whilst those with pulmonary tuberculosis were 5 (4.4%). C. albicans 22.58% and Aspergillus species 17.20%) were the most aetiological agents for pulmonary mycoses identified among others. Of those who were TB GeneXpert positive, 2 (1.77%) of them were co-infected with pulmonary mycoses. We established a prevalence of 57 (71.3%) for PFI, 3 (60.0%) for MTB in HIV sero positive patients and 18 (22.5%) for PFI, 0 (0.00%) for MTB in HIV sero negative patients. On the other hand, 2 (100%) sero positive patients were co-infected with both PFI and MTB.Conclusion: Our findings highlight the medical importance of pulmonary fungal infections among patients suspected for TB. Importantly, the aetiological diversity established here is rich enough to suggest precise examination using different methods. Established scope of aetiological agents is predominated by opportunistic fungi which when superimposed on to certain underlying conditions such as TB, their effects can be fatal. Therefore this possibility presents a need to employ appropriate strategies for prevention, diagnosis, and management in TB suspects.

scholarly journals A clinical study of diabetic dermatological manifestations at a tertiary care hospital in South India

2018 ◽  
Vol 4 (3) ◽  
pp. 293
Author(s):  
Vani G. ◽  
L. Venkat Narsimha Reddy
Keyword(s):  
Bacterial Infections ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Skin Lesions ◽  
Cross Sectional Study ◽  
Diabetic Patients ◽  
Care Hospital ◽  
Cross Sectional ◽  
Cutaneous Infections ◽  
One Year

<p class="abstract"><strong>Background:</strong> The data on studies like lesions of the skin due to diabetes are scarce. Hence there is a need to conduct more studies on this topic of importance. The objective of the study was to study diabetic dermatological manifestations.</p><p class="abstract"><strong>Methods:</strong> A hospital based cross sectional study was carried out among 100 randomly selected patients during the study period of one year who were having diabetes as well as skin lesions due to diabetes. All diabetic patients were screened for presence of skin lesions. They were further differentiated based on the diagnosis.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of 73 patients having cutaneous infections 71.2% were having fungal infections. Out of 18 having bacterial infections 38.9% were having furuncles. Out of 52 having fungal infections 63.5% were having dermatophytosis. Out of 14 cases of candidal infections, the most common was intertrigo in 35.7%. Out of 33 cases of dermatophytosis, T. cruris was the most common in 54.5%. Out of 82 patients in whom we suspected dermatoses strongly associated with diabetes the most common condition was pruritus in 36.6% of the cases.</p><p class="abstract"><strong>Conclusions:</strong> Bacterial skin infections and dermatophytosis were the most common diabetic dermatological lesions in the present study.</p>

scholarly journals Ophthalmic manifestations of SARS-CoV-2 (COVID-19)

2021 ◽  
Vol 7 (2) ◽  
pp. 293-301
Author(s):  
Aastha Garg ◽  
Sandhya Ramachandra
Keyword(s):  
Cavernous Sinus ◽  
Sinus Thrombosis ◽  
Tertiary Care ◽  
Orbital Cellulitis ◽  
Care Hospital ◽  
Cavernous Sinus Thrombosis ◽  
Cross Sectional ◽  
Systemic Involvement ◽  
Ocular Manifestations ◽  
Ophthalmic Manifestations

The world has been dealing with the pandemic of COVID-19 since December 2019. The systemic manifestations of the disease are well known. Our study aims to evaluate the ocular manifestations of SARS-CoV-2 (COVID-19). This cross-sectional observational study comprised of 60 subjects that tested positive for COVID-19 by RT-PCR, and admitted to the general wards of a tertiary care hospital of South India. Relevant medical history, ocular history, symptoms, signs and blood investigations data were obtained by communicating directly with the subjects and patient files. Ocular examination was done using diffuse torch light.15% patients presented with conjunctivitis in association with increased conjunctival secretion, tearing and burning sensation. 3.33% patients presented with dry eye disease and orbital cellulitis each. 1.67% patients developed epiphora, cavernous sinus thrombosis and orbital cellulitis with retinal detachment each. A statistically significant correlation was found between the provisional diagnosis and C-reactive protein (CRP) values.Conjunctival congestion can be one of the ocular symptoms of COVID-19. Asymptomatic COVID-19 patients may primarily present to an ophthalmologist with red eye, thus universal precautions must be taken while examining such cases. Evaluation of symptomatic patients with orbital cellulitis and cavernous sinus thrombosis can further aid in understanding the ophthalmic implications, pathogenesis and systemic involvement of this disease.

scholarly journals Clinico-Mycological Profile of Dermatophytosis in a Tertiary Care Hospital of Eastern Nepal

2021 ◽  
Vol 10 (2) ◽  
pp. 3-6
Author(s):  
Kewal Shrestha ◽  
Sujit Kumar Bhattacharjee ◽  
Kumari Ragani Yadav
Keyword(s):  
Clinical Presentation ◽  
Tertiary Care ◽  
Trichophyton Mentagrophytes ◽  
Tinea Corporis ◽  
Etiological Agent ◽  
Care Hospital ◽  
Biochemical Tests ◽  
Isolation And Identification ◽  
Cross Sectional ◽  
Delay In Diagnosis

Background: Dermatophytes are keratinophilic and keratinolytic fungi which are responsible for dermatophytosis. There are three genera of dermatophytes; Trichophyton, Microsporum and Epidermophyton. As they have affinity to keratin rich tissue, they produce dermal inflammatory response, intense itching and cosmetically poor appearance. The varied clinical presentation of tinea results in delay in diagnosis, poor compliance in follow up of cases, and consequently spread of infection in the community has rekindled interest in rapid identification of species. Materials and Methods: A hospital based cross sectional study was carried out in the department of Microbiology, Nobel medical college from January 2019 to December 2019. Clinically suspected 200 cases of dermatophytosis attending Out Patient Department were studied. Isolation and identification was done by various tests like macroscopic, microscopic and biochemical tests. Results: Out of 200 specimens, 138 (69%) were skin scraping, 42 (21%) were nail clipping and 20 (10%) were hair stubs. Highest incidence was seen in the age group 21-40 years with 115 (57.5%) cases followed by 41-60 years 46 (23%) cases. In our study male preponderance of 158 (79%) and female of 42 (21%) were seen. Tinea corporis was found to be the commonest clinical type with 96 (48%) cases followed by tinea unguinum, 42 (21%), Tinea cruris 10 (11.36%), Tinea capitis 5 (5.68%), Tinea faciei 4 (4.54%), Tinea pedis 2 (2.27%). Among the fungal isolates Trichophyton rubrum (67.04%) was the most common etiological agent followed by Trichophyton mentagrophytes (13.63%), Epidermophyton 10 (11.36%), Trichophyton violaceum 4 (4.54%) and Epidermophyton floccosum 3 (3.4%). Conclusion: The most common clinical presentation was tinea corporis followed by tinea unguinum. T. rubrum was the most common etiological agent of dermatophytosis

scholarly journals Fungal Infections among Teledermatology Consultations in Dermatology Department of a Tertiary Care Hospital: A Descriptive Cross-sectional Study

2021 ◽  
Vol 59 (243) ◽  
pp. 1094-1097
Author(s):  
Sagar Mani Jha ◽  
Anil Kumar Singh Dangol ◽  
Bhabendra Suwal ◽  
Jyotshna Yadav
Keyword(s):  
Confidence Interval ◽  
Binary Data ◽  
Tertiary Care Hospital ◽  
Fungal Infections ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Sectional Study ◽  
Cross Sectional ◽  
Dermatology Department

Introduction: Teledermatology provides virtual consultation to patients using telecommunication technology. Using this method dermatologists can diagnose a condition with the help of pictures of the lesions and short history. During the COVID-19 pandemic, practicing this method has become more relevant. Providing teleconsultations to patients with fungal skin infections can prevent inadvertent use of topical corticosteroids. The objective of this study was to find the prevalence of fungal infections among teledermatology consultations done in a tertiary care hospital. Methods: It was a descriptive cross-sectional study where the store and forward and real-time methods were used between February 2020 to July 2020. Ethical clearance was taken from the institutional review board (reference number: 245). Data of those patients who wanted consultations from this department were sent by medical officers deployed in military hospitals that are under the central army hospital located in Kathmandu. Convenient sampling was used. The collected data was entered and analyzed in the Statistical Package of Social Sciences version 20. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data. Results: A total of 451 (33.45%) (30.93-35.97 at 95% Confidence Interval) were diagnosed with fungal infections out of 1348 patients who were enrolled for the study. About 361 (80%) of the patients suffering from fungal infections belonged to the Terai region and 90 (20%) belonged to mountainous areas. Conclusions: The prevalence of fungal infection among teledermatology consultation was lower than the findings from a similar international study.

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