scholarly journals Age-and Gender-Related Differences in Anticoagulant Drugs Use Patterns

Author(s):  
Nehad J. Ahmed

Aim: Drug utilization study is considered a powerful exploratory tool to assess the present trends of drug prescribing and appropriateness of prescription and to analyze the differences in drugs utilization with respect to several factors such as age and gender. This study aims to describe the age-and gender-related differences in anticoagulant drugs use patterns. Methodology: The present study included the review of outpatient electronic prescriptions that include an anticoagulant drug in 2018 in a public hospital in Al-karj, Saudi Arabia. Results: Enoxaparin was prescribed mainly for patients between 20-39 years old (63.48%). Warfarin was prescribed mainly for patient more than 50 years old (59.38%). Enoxaparin was prescribed mainly for female patients (86.09%). Rivaroxaban and warfarin were prescribed mainly for female patients, 64.71% and 59.38% respectively. Conclusion: There are differences in prescribing anticoagulant according to gender and age. It is important to know the differences in prescribing anticoagulants according to age and gender and if the treatment is inappropriate, it is important to identify and address reasons for treatment disparities in anticoagulation prescription.

2020 ◽  
Vol 12 (2) ◽  
pp. 70-79
Author(s):  
FlávioAlberto Oliva ◽  
Maria Lúcia Ribeiro ◽  
Marina Armelin Silva ◽  
Marjori Leiva Camparoto ◽  
Telma Reginato Martins

The goal of this study was to understand the gender and age profile of the users of ambulatory services at public hospital. Gender and age are fundamental elements for the construction of public policies at local and regional level. We performed a 3-year retrospective data collection, regarding age and gender of the population of the outpatient clinic of the public hospital between 2013 and 2015. It is a research with quantitative approach performed through three databases from january 2013 to December 2015 totaling 460.505 consultations. The database of the public hospital was adopted as the primary source, it was also consulted the database of the last two censuses of the Brazilian Institute of Geography and Statistics (IBGE) and the database of the Regional Health Division. The cross-checking of data, through Microsoft Excel and the Online Analytical Processing (OLAP) software, allowed the construction of a graph structured by gender and age according to the standards defined by IBGE on 2010, as well as the comparison between age and gender profile of the total population attended by public hospital and its consultations. The female audience represents 60.5% of the attendances, while the male population accounts for 39.5%. Only in the age groups between 0 and 14 and 85 to 89 years the male audience is larger. The difference in care is accentuated in the middle of the pyramid, in the ranges between 30 and 69 years, during which time women are responsible for 65.5% of the attendances against 34.5% of men. Such gender proportional differences are maintained on the total population, the only significant variation is on the age group from 80 and older where although there is a female majority of users, there is also a larger female majority on the population. Studies show that women make more references to health problems than men, as these represent, according to the male imagination, virility and strength, not representing vulnerability to the disease. Men do not recognize themselves as targets of health care and they are less likely to seek health services for cultural reasons, mainly, opening space for discussion about social inequalities in health between men and women.


Author(s):  
Nehad J. Ahmed ◽  
Menshawy A. Menshawy ◽  
Ziyad S. Almalki ◽  
Mohammed A. Alhajri

Aim: Lipid-lowering drugs are used to decrease low-density lipoprotein cholesterol and as a result, they are used in both secondary and primary prevention of cardiovascular diseases. This study aimed to observe the prescribing trend of lipid-lowering drugs and to describe the gender and age-related differences in the outpatient setting of a public hospital in Alkharj city. Methodology: This is a cross-sectional observational study that was conducted in outpatient setting of a public hospital in Alkharj city and included the review of electronic outpatient prescriptions. The data was collected and analyzed using Excel software; the descriptive data were represented by percentages and numbers.  Results: The most prescribed lipid-lowering drug in the present study was atorvastatin (62.36%) followed by simvastatin (29.34%). The study found that there are several differences in lipid lowering medications use patterns among different gender and age groups. Therefore, frequent reviews of lipid-lowering drugs use and prescribing pattern are important to optimize patients’ treatment. Conclusion: It is important in the future to make stratified guidelines based on patient characteristics such as age and gender.


Electronics ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 835
Author(s):  
Ioannis Tsimperidis ◽  
Cagatay Yucel ◽  
Vasilios Katos

Keystroke dynamics are used to authenticate users, to reveal some of their inherent or acquired characteristics and to assess their mental and physical states. The most common features utilized are the time intervals that the keys remain pressed and the time intervals that are required to use two consecutive keys. This paper examines which of these features are the most important and how utilization of these features can lead to better classification results. To achieve this, an existing dataset consisting of 387 logfiles is used, five classifiers are exploited and users are classified by gender and age. The results, while demonstrating the application of these two characteristics jointly on classifiers with high accuracy, answer the question of which keystroke dynamics features are more appropriate for classification with common classifiers.


Author(s):  
Lora I. Dimitrova ◽  
Eline M. Vissia ◽  
Hanneke Geugies ◽  
Hedwig Hofstetter ◽  
Sima Chalavi ◽  
...  

AbstractIt is unknown how self-relevance is dependent on emotional salience. Emotional salience encompasses an individual's degree of attraction or aversion to emotionally-valenced information. The current study investigated the interconnection between self and salience through the evaluation of emotional valence and self-relevance. 56 native Dutch participants completed a questionnaire assessing valence, intensity, and self-relevance of 552 Dutch nouns and verbs. One-way repeated-measures ANCOVA investigated the relationship between valence and self, age and gender. Repeated-measures ANCOVA also tested the relationship between valence and self with intensity ratings and effects of gender and age. Results showed a significant main effect of valence for self-relevant words. Intensity analyses showed a main effect of valence but not of self-relevance. There were no significant effects of gender and age. The most important finding presents that self-relevance is dependent on valence. These findings concerning the relationship between self and salience opens avenues to study an individual's self-definition.


Author(s):  
Pierluigi Carcagnì ◽  
Dario Cazzato ◽  
Marco Del Coco ◽  
Pier Luigi Mazzeo ◽  
Marco Leo ◽  
...  

AbstractIn thiswork, a real-time system able to automatically recognize soft-biometric traits is introduced and used to improve the capability of a humanoid robot to interact with humans. In particular the proposed system is able to estimate gender and age of humans in images acquired from the embedded camera of the robot. This knowledge allows the robot to properly react with customized behaviors related to the gender/age of the interacting individuals. The system is able to handle multiple persons in the same acquired image, recognizing the age and gender of each person in the robot’s field of view. These features make the robot particularly suitable to be used in socially assistive applications.


Author(s):  
Igor Linskiy ◽  
Valerii Kuzminov ◽  
Oleksandr Minko ◽  
Hanna Kozhyna ◽  
Yevheniia Grynevych ◽  
...  

The purpose of the work is to determine in the Ukrainian society the scale of harm inflicted by drinkers to other persons, as well as the gender and age characteristics of this harm. In four regions of Ukraine (Kharkiv, Lugansk and Zaporizhzhia regions, Kyiv), during 2018-2020, 1,742 people were examined from three qualitatively different comparison groups: patients with alcohol dependence (393 people); their healthy relatives (274 people) and representatives of the general population (1075 people). The main research tool was the questionnaire of the international research consortium GENAHTO (Gender, Alcohol, and Harms to Others). It was shown that, in general, drinkers are present in the microsocial environment of 27.62 % of the surveyed healthy respondents. Extrapolation of this indicator to the entire population of Ukraine suggests that the total number of people who suffer in one way or another due to the drinkers in their environment is about 11.6 million people. In addition, the drinkers frequency in the environment of respondents can be used to determine the real number of people with alcohol problems in our country. Preliminary calculations indicate that this number is from 1.5 to 2.2 million people. The drinkers frequency in the environment of the respondents significantly depends on the age of the latter. The highest values of this indicator are characteristic of the respondents in the age category 40—59 years old” (31.43 % for men and 41.27 % for women). The subjective perception of harm from drinkers in the environment grows steadily with increasing age of the respondents, while this growth is most pronounced in women.


2002 ◽  
Vol 41 (03) ◽  
pp. 202-208 ◽  
Author(s):  
I. Yamasawa ◽  
S. Kamohara ◽  
M. Shiota ◽  
T. Komori ◽  
Y. Watanabe ◽  
...  

Summary Objectives: To improve insight into age and gender related distributions of serum lipids and their correlation with body mass index (BMI). Methods: Serum lipids embracing atherogenic index (AI) and BMI were analyzed from the results obtained in 19,823 men and 14,788 women undergoing a health examination between 1986 and 1996. Results: The changes in total cholesterol (TC), triglyceride (TG), AI and BMI differed regarding gender. Although high-density lipoprotein-cholesterol (HDL-C) showed a flat pattern for all ages in both genders, its level in women was higher than in men. The ratio of the number in the unsuitable range to those in the suitable range increased with age as to TC in both sexes, then more than half of the population have an unsuitable level in the sixth decade. As for the correlation between serum lipids and BMI: TC, TG and AI correlated positively, but HDL-C correlated negatively. There were significant gaps between both age and gender. Conclusions: We suggest that the normal range of values of serum lipids needs to be revised according to gender and age to evaluate the risk status for a cardio-cerebrovascular disease more precisely in the field of preventive medicine. Simpler guidelines are preferable in specialized care as well as in general practice, particularly since computer technology is not yet universally adapted. In the near future, when computed information technology will be as common as the electricity and the telephone are current on the whole earth, all guidelines will have to be computed on the spot and personally.


2019 ◽  
Vol 114 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Jackson K Mukonzo ◽  
Allan Kengo ◽  
Bisaso Kutesa ◽  
Sarah Nanzigu ◽  
Anton Pohanka ◽  
...  

Abstract Background Suboptimal anti-TB drugs exposure may cause multidrug-resistant TB. The role of African predominant SLCO1B1 variant alleles on rifampicin pharmacokinetics and the subsequent effect on the occurrence of Mycobacterium tuberculosis–rifampicin sensitivity needs to be defined. We describe the rifampicin population pharmacokinetics profile and investigate the relevance of SLCO1B1 genotypes to rifampicin pharmacokinetics and rifampicin-TB sensitivity status. Methods Fifty patients with TB (n=25 with rifampicin-resistant TB and n=25 with rifampicin-susceptible TB) were genotyped for SLOC1B1 rs4149032 (g.38664C>T), SLOC1B1*1B (c.388A>G) and SLOC1B1*5 (c.521 T>C). Steady state plasma rifampicin levels were determined among patients infected with rifampicin-sensitive TB. Data were analysed using NONMEM to estimate population rifampicin pharmacokinetics as well as the effect of SLOC1B1 genotypes on rifampicin pharmacokinetics and on rifampicin-TB sensitivity status. Results Overall allele frequencies of SLOC1B1 rs4149032, *1B and *5 were 0.66, 0.90 and 0.01, respectively. Median (IQR) Cmax and Tmax were 10.2 (8.1–12.5) mg/L and 1.7 (1.125–2.218) h, respectively. Twenty-four percent of patients exhibited Cmax below the recommended 8–24 mg/L range. SLOC1B1 genotypes, gender and age did not influence rifampicin pharmacokinetics or TB-rifampicin sensitivity. Conclusions Although SLOC1B1 genotype, age and gender do not influence either rifampicin pharmacokinetics or rifampicin-TB sensitivity status, one in every four Ugandan TB patients achieve subtherapeutic plasma rifampicin concentrations.


2020 ◽  
Vol 10 (17) ◽  
pp. 5957 ◽  
Author(s):  
Roberto Garcia-Guzman ◽  
Yair A. Andrade-Ambriz ◽  
Mario-Alberto Ibarra-Manzano ◽  
Sergio Ledesma ◽  
Juan Carlos Gomez ◽  
...  

Category suggestions or recommendations for customers or users have become an essential feature for commerce or leisure websites. This is a growing topic that follows users’ activity in social networks generating a huge quantity of information about their interests, contacts, among many others. These data are usually collected to analyze people’s behavior, trends, and integrate a complete user profile. In this sense, we analyze a dataset collected from Pinterest to predict the gender and age by processing input images using a Convolutional Neural Network. Our method is based on the meaning of the image rather than the visual content. Additionally, we propose a heuristic-based approach for text analysis to predict users’ age and gender from Twitter. Both of the classifiers are based on text and images and they are compared with various similar approaches in the state of the art. Suggested categories are based on association rules conformed by the activity of thousands of users in order to estimate trends. Computer simulations showed that our approach can recommend interesting categories for a user analyzing his current interest and comparing this interest with similar users’ profiles or trends and, therefore, achieve an improved user profile. The proposed method is capable of predicting the user’s age with high accuracy, and at the same time, it is able to predict gender and category information from the user. The certainty that one or more suggested categories be interesting to people is higher for those users with a large number of publications.


2014 ◽  
Vol 17 ◽  
Author(s):  
Elena Felipe-Castaño ◽  
Benito León-del-Barco ◽  
José Antonio López-Pina

AbstractTo provide questionnaires for clinical assessment with scales adapted for adolescents would benefit clinical practice as well as research. The aim of this paper is to report normative data for adolescents on the SCL-90-R using a probability sample from the community. The participants were 1,663 adolescents, 845 girls and 818 boys, with an average age of 14.26 (SD = 1.36). They were selected through stratified cluster sampling with groups randomly selected from schools. Sampling error was estimated at 4% with a 95.5% confidence level. Cohen´s d effect sizes are reported for age-group. We found significant differences across participants according to gender and age on SCL-90-R Global Scores and Symptom Dimensions. Thus, we provide normative data, divided according to age and gender.


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