Parameters Identification for Three Groups of Squirrel Induction Motor

This paper presents a developed method to calculate the parameters for thirty-three squirrel cage induction motors operating at three-phase ac voltage of 380 volts. These motors are the total product of an Egyptian factory holding a license from SIEMENS international company to fabricate all parts of these motors. The parameters of all mentioned motors are computed based on the proposed method. Then, the performance characteristics of these motors are investigated at full-load using the conventional equivalent circuit in order to validate the proposed method. The obtained curves achieve significant convergence with the full-load values provided by the data sheets of investigated motors. This confirms the validity of the proposed method.

Bridging the Gap: The Critical Role of Regulatory Affairs and Clinical Affairs in the Total Product Life Cycle of Pathology Imaging Devices and Software

Manufacturers of pathology imaging devices and associated software engage regulatory affairs and clinical affairs (RACA) throughout the Total Product Life Cycle (TPLC) of regulated products. A number of manufacturers, pathologists, and end users are not familiar with how RACA involvement benefits each stage of the TPLC. RACA professionals are important contributors to product development and deployment strategies because these professionals maintain an understanding of the scientific, technical, and clinical aspects of biomedical product regulation, as well as the relevant knowledge of regulatory requirements, policies, and market trends for both local and global regulations and standards. Defining a regulatory and clinical strategy at the beginning of product design enables early evaluation of risks and provides assurance that the collected evidence supports the product's clinical claims (e.g., in a marketing application), its safe and effective use, and potential reimbursement strategies. It is recommended to involve RACA early and throughout the TPLC to assist with navigating changes in the regulatory environment and dynamic diagnostic market. Here we outline how various stakeholders can utilize RACA to navigate the nuanced landscape behind the development and use of clinical diagnostic products. Collectively, this work emphasizes the critical importance of RACA as an integral part of product development and, thereby, sustained innovation.

AI/ML Models to Aid in the Diagnosis of COVID-19 Illness from Forced Cough Vocalizations: Results and Challenges of a Systematic Review of the Relevant Literature

From a comprehensive and systematic search of the relevant literature on signal data signature (SDS)-based artificial intelligence/machine learning (AI/ML) systems designed to aid in the diagnosis of COVID-19 illness, we aimed to reproduce the reported systems and to derive a performance goal for comparison to our own medical device with the same intended use. These objectives were in line with a pathway to regulatory approval of such devices, as well as to acceptance of this unfamiliar technology by disaster/pandemic decision makers and clinicians. To our surprise, none of the peer-reviewed articles or pre-print server records contained details sufficient to meet the planned objectives. Information amassed from the full review of more than 60 publications, however, did underscore discrete impediments to bringing AI/ML diagnostic solutions to the bedside during a pandemic. These challenges then were explored by the authors via a gap analysis and specific remedies were proposed for bringing AI/ML technologies in closer alignment with the needs of a Total Product Life Cycle (TPLC) regulatory approach.

Neglected Theories of Business Cycle—Alternative Ways of Explaining Economic Fluctuations

The business cycle is a frequent topic in economic research; however, the approach based on individual strategies often remains neglected. The aspiration of this study is to prove that the behavior of individuals can originate and fuel an economic cycle. For this purpose, we are using an algorithm based on a repeated dove–hawk game. The results reveal that the sum of output in a society is affected by the ratio of individual strategies. Cyclical changes in this ratio will be translated into fluctuations of the total product of society. We present game theory modelling of a strategic behavioral approach as a valid theoretical foundation for explaining economic fluctuations. This article offers an unusual insight into the business cycle’s causes and growth theories.

E-Commerce Business Strategy Creative Clothing Industry In Kuta Region In The New Normal Era

The purpose of this study is to determine Huck's business strategy in the marketplace to face the new normal era in preparing and implementing the strategy. The type of data used in this study is data collection through interviews and observation. The data That have been collected analyzed using an triangulation model data analysis. The results of data analysis obtained by Huck's business strategy to build an online store in the marketplace using an e-marketing strategy which is divided into product and service, price, placement and distribution, promotion, and people. The purpose of using this strategy is to find out the accuracy in choosing strategies in online marketplace stores and get sales targets through online stores in the midst of the Covid-19 pandemic. The strategy that has been implemented for a year has resulted in 100 total product sales and received the star seller title in marketplace also getting chat performance of 44%.

Gene Therapy: Development, Design of Studies, and Approval Process

Genome editing can be applied to various areas of medical diagnosis and treatments. Gene therapy pre-market applications comprise of systematically assessing a product’s design controls, manufacturing process controls, and proposed protocols for post-marketing surveillance. Quality risk management principles have been described in various FDA regulatory guidances for several aspects of good manufacturing practices (GMPs) such as several stages of process validation and verification in the genome product’s life cycle including critical quality attributes (CQAs) and monitoring critical process parameters (CPPs). A CPP is defined as a process parameter whose variability has an impact on a CQA of genome product and, therefore, should be monitored or controlled to ensure that the manufacturing process produces an end product of the desired quality. FDA’s mission is to facilitate the premarket review and evaluation of new genomic products for clinical use. The FDA guidances emphasize a quality management approach to the design of studies by providing oversight and objective review based on risk-benefit analysis of new genomic products. FDA reviews, evaluates, verifies and validates the implementation of the regulatory design-control requirements which are applied to the control genomic product’s quality throughout the total product life cycle (TPLC) [1-5].

THE INVESTIGATION OF LEAN MODELS ADOPTION IN SMEs OF SINDH PROVINCE

Small and Medium Enterprises (SMEs) are the foundation of every major economy in the world. The majority of these industries are fighting for survival in a hostile climate. In the SMEs sector, the Lean models have been implemented with an emphasis on economic efficiency. The various Lean Models are used in SMEs as well as in large Industries. The Lean Models are considered for the improvement of company performance which includes production, productivity, inventory, raw material, quality, and customer satisfaction. therefore, in this research work which lean models are being implemented in SMEs of Sindh was investigated. The survey questionnaires were distributed amongst 70 SMEs of Sindh based on Six Sigma, 5S, Green Manufacturing, Kaizen, Poka Yoke, TPM, TQM, SCM, Standardize of Work lean models. The results conclude that 5’s and Standardize of work are mostly implemented about 87.5% & 72.9% as compared to the other models. whereas PokaYoke Model and Total Product Management Model are considered as least implemented the model in SMEs with 18.6% and 10%. Moreover, in terms of location, Hyderabad seems highly impacted region in Lean Model Implementation

Quamtum Mechanical Approach to Gas Phase Reaction of Isopropanol with Sulfanyl Radical

i-C3H7OH (IPA) is one of the potential fuel additives. The reaction mechanism of isopropanol with sulfanyl radical was investigated at the CCSD(T)//B3LYP/6-311+G(3df,2p) level of theory. Ten possible reaction pathways giving PR1-PR10 including three H-abstraction reactions and seven substitution reactions were considered. Based on the determined potential energy surface and molecular parameters, the rate constants and branching ratios of each reaction pathway were calculated at the temperature range of 298K - 2000K by using the transition state theory considering the Eckart tunnel effect. The kinetics results showed that at 298K, the reaction products were mainly PR2 ((CH3)2COH + H2S) (~ 100%). However, at 2000K, the contribution of PR2 decreased to 77.8% of the total product, while, PR3 (CH3CH(CH2)OH + H2S) and PR1 ((CH3)2CHO + H2S) accounted for 16.7% and 5.5% of the total product, respectively.

Marketable dan Merketed Surplus Beras di Kabupaten Banyumas

Efforts to increase rice production must be integrated from the upstream sub-system, the farming sub-system, the downstream sub-system and the support sub-system. Upstream sub-system development is very important and cannot be ignored. Ownership of land by farmers is very small with an area of less than 0.5 hectares, most farmers are actually only landless farm laborers who depend on their work as agricultural laborers. Rice farmers in Banyumas Regency cannot be clearly defined as a producer when looking at the consumption side of the farmer. This study aims to determine the performance of rice farming, determine the magnitude of marketable surpluses and marketed surpluses of rice and analyze the factors that influence the marketed surpluses of rice in Banyumas Regency. Data analysis uses marketable analysis and marketed rice surplus, multiple linear analysis. The results showed an average area of land owned by 0.21 ha, with a productivity of 4,823.69 kg / Ha (GKP), 4,149.34 kg / Ha (GKG), 2,603.30 kg / Ha (Rice). The marketable value of rice surplus is 22,624.20 kg / MT or 85.67 percent of the total product and the marketed value of rice surplus is 13,422.83 kg / MT or 59.33 percent of the marketable surplus value. Product allocation is more used to pay for harvest labor and family food consumption. The results of multiple linear regression analysis with the model obtained Y = -146.89 + 0.87X1-1.94X2 + 4.94X3 + 1X4-83.80X5-0.009X6 + 2.95X7-7.23X8-1.6X9 + 34 , 3X10-0.007X11 + e. Marketed rice surpluses in Banyumas Regency are influenced by the variable amount of products and farming costs in nature.

Perspectives on the pharmacist’s “product”: a narrative review

Clarity about the pharmacist’s “product” is fundamental to developing and communicating the value of pharmacy offerings. It is clear within the profession that pharmacists use their scope of knowledge and technical skills to address medication-related needs of individuals and populations. However, confusion still remains in the professional and public literature about what a pharmacist precisely produces for society. Is it a drug, service, program, solution, or something else? As the profession evolves from one that focuses on dispensing drugs to a profession that seeks to achieve positive patient health outcomes, pharmacists need to better conceptualize and articulate what they produce. This narrative review explores ideas from the marketing, business strategy, and entrepreneurship literature to discuss diverse perspectives on the pharmacist’s product. The four perspectives are the product as (1) a tangible product, (2) an intangible service, (3) a “smart, connected” good or service, and (4) a solution to a customer problem in whatever form provided. Based upon these perspectives, the pharmacist’s product can be any combination of tangible or intangible, face-to-face or virtual offering produced by pharmacists that seeks to satisfy medication-related needs and wants of pharmacy patients and customers. Ideas discussed in this review include the total product concept, classification schemes from the services marketing literature, the theory of service-dominant logic, the concepts of “smart, connected” products and industrialized intimacy, and the jobs-to-be-done framework. These various perspectives offer lessons for pharmacists on how to innovate when serving patients and customers and to communicate the pharmacist’s value proposition to the people they serve.