Abstract
Aims: To assess the clinical outcomes of patients with endophthalmitis.We also aimed the effect of comorbidities on hospitalization time, treatment management and vision gain.Metods: This retrospective study includes 40 eyes of 40 patients.Endophthalmitis was divided into as exogenous and endogenous groups.We investigated that culture results, comorbidities, hospitalization times, treatment management and vision gain.Patients with diabetes mellitus(DM) and/or hypertension(HT) were placed under comorbidity group 1.Patients with chronic distant organ inflammation in addition to DM and/or HT were placed under comorbidity group 2.Results: Endophthalmitis were exogenous origin in 25 eyes, endogenous origin in 15 eyes.Culture positivity rate,pars plana vitrectomy(PPV) rate,Intravitreal injection(IVI) rate,rePPV rate,two IVIs rate,more than two IVIs rate in exogenous and endogenous groups were 16%, 20%, respectively(culture positivity); 56%, 86.7%, respectively(PPV); 44%, 13.3%, respectively(IVI); 4%, 20%, respectively(rePPV); 52%, 6.7%, respectively(two IVIs); 20%, 66.7%, respectively(more than two IVIs).In exogenous group, mean hospitalization time in comorbidity group 1 and comorbidity group 2 was 7.3 ± 2.5, 10.5 ± 2.8 days, respectively.Mean number of IVIs in comorbidity group 2 was 28% more than comorbidity group 1.In endogenous group, mean hospitalization time in comorbidity group 1 and comorbidity group 2 was 14.3 ± 10.1, 22.0 ± 6.79 days, respectively.Mean number of IVIs in comorbidity group 2 was 86% more than comorbidity group 1.Conclusions: Because our culture and antibiogram findings were low, we had to increase surgical procedures and repeat IVI.This study showed that patients with chronic distant organ inflammation in addition to DM and/or HT encountered increased hospitalization times and IVI requirements.