Fabrication of aerosol-based nanoparticles and their applications in biomedical fields

: Nanobiotechnology has huge potential in the field of regenerative medicine. One of the main drivers has been the development of novel nanomaterials. One developing class of materials is graphene and its derivatives recognized for their novel properties present on the nanoscale. In particular, graphene and graphene-based nanomaterials have been shown to have excellent electrical, mechanical, optical and thermal properties. Due to these unique properties coupled with the ability to tune their biocompatibility, these nanomaterials have been propelled for various applications. Most recently, these two-dimensional nanomaterials have been widely recognized for their utility in biomedical research. In this review, a brief overview of the strategies to synthesize graphene and its derivatives are discussed. Next, the biocompatibility profile of these nanomaterials as a precursor to their biomedical application is reviewed. Finally, recent applications of graphene-based nanomaterials in various biomedical fields including tissue engineering, drug and gene delivery, biosensing and bioimaging as well as other biorelated studies are highlighted.

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Graphene Integrated Hydrogels Based Biomaterials in Photothermal Biomedicine

Nanomaterials ◽

10.3390/nano11040906 ◽

2021 ◽

Vol 11 (4) ◽

pp. 906

Author(s):

Le Minh Tu Phan ◽

Thuy Anh Thu Vo ◽

Thi Xoan Hoang ◽

Sungbo Cho

Keyword(s):

Photothermal Therapy ◽

Biomedical Applications ◽

High Light ◽

Conversion Materials ◽

Potential Applications ◽

Good Biocompatibility ◽

Biomedical Field ◽

Hydrogel Composites ◽

Material Fabrication ◽

Biomedical Fields

Recently, photothermal therapy (PTT) has emerged as one of the most promising biomedical strategies for different areas in the biomedical field owing to its superior advantages, such as being noninvasive, target-specific and having fewer side effects. Graphene-based hydrogels (GGels), which have excellent mechanical and optical properties, high light-to-heat conversion efficiency and good biocompatibility, have been intensively exploited as potential photothermal conversion materials. This comprehensive review summarizes the current development of graphene-integrated hydrogel composites and their application in photothermal biomedicine. The latest advances in the synthesis strategies, unique properties and potential applications of photothermal-responsive GGel nanocomposites in biomedical fields are introduced in detail. This review aims to provide a better understanding of the current progress in GGel material fabrication, photothermal properties and potential PTT-based biomedical applications, thereby aiding in more research efforts to facilitate the further advancement of photothermal biomedicine.

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A critical review on human serum Paraoxonase-1 in the literature: truths and misconceptions

Turkish Journal of Biochemistry ◽

10.1515/tjb-2020-0186 ◽

2020 ◽

Vol 0 (0) ◽

Author(s):

Michael Mackness ◽

Eser Yildirim Sozmen

Keyword(s):

Heart Disease ◽

Experimental Design ◽

Human Serum ◽

Critical Review ◽

Neurological Diseases ◽

Rapid Expansion ◽

Paraoxonase 1 ◽

Serum Paraoxonase ◽

Inflammatory Component ◽

Biomedical Fields

AbstractHuman serum paraoxonase 1 (PON1) appears to play an important role in the development of a large variety of diseases with an inflammatory component including heart disease, diabetes, rheumatic diseases, neurological diseases and cancer. As such PON1 research is rapidly expanding into new biomedical fields. Unfortunately, this rapid expansion has resulted in a number of problems due to poor experimental design and the spreading of misconceptions in the literature. This review seeks to describe the basic properties of PON1 and the problems and misconceptions that have arisen.

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Near-Field Communication in Biomedical Applications

Sensors ◽

10.3390/s21030703 ◽

2021 ◽

Vol 21 (3) ◽

pp. 703

Author(s):

Sung-Gu Kang ◽

Min-Su Song ◽

Joon-Woo Kim ◽

Jung Woo Lee ◽

Jeonghyun Kim

Keyword(s):

Blood Flow ◽

Communication Technology ◽

Biomedical Applications ◽

Daily Life ◽

Near Field ◽

Near Field Communication ◽

Disease Monitoring ◽

Payment Methods ◽

New Sensors ◽

Biomedical Fields

Near-field communication (NFC) is a low-power wireless communication technology used in contemporary daily life. This technology contributes not only to user identification and payment methods, but also to various biomedical fields such as healthcare and disease monitoring. This paper focuses on biomedical applications among the diverse applications of NFC. It addresses the benefits of combining traditional and new sensors (temperature, pressure, electrophysiology, blood flow, sweat, etc.) with NFC technology. Specifically, this report describes how NFC technology, which is simply applied in everyday life, can be combined with sensors to present vision and opportunities to modern people.

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Optical Temperature Sensing of Core-Shell Structured NaYF4:Yb3+, Er3+@NaYF4 Nanocrystals with Different Shell Thickness

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.738-739.27 ◽

2015 ◽

Vol 738-739 ◽

pp. 27-30

Author(s):

Dong Dong Li ◽

Qi Yue Shao ◽

Yan Dong ◽

Jian Qing Jiang

Keyword(s):

Shell Thickness ◽

Thermal Sensitivity ◽

Upconversion Luminescence ◽

Temperature Sensing ◽

Upconversion Nanoparticles ◽

Core Shell ◽

Sensing Properties ◽

The Core ◽

Β Phase ◽

Biomedical Fields

Hexagonal (β)-phase NaYF4:Yb3+, Er3+ upconversion nanoparticles (UCNPs) with and without an inert (undoped NaYF4) shell have been successfully synthesized and the effects of shell thickness on the upconversion luminescence (UCL) and temperature sensing properties were systematically investigated. It was found that the NaYF4 shell and its thickness do not affect the RHS values and thermal sensitivity, but can obviously improve the UCL intensity of NaYF4:Yb3+, Er3+ UCNPs. It implies that the core-shell structured NaYF4:Yb3+, Er3+@NaYF4 UCNPs with excellent UCL properties have great potential to be used as temperature sensing probes in biomedical fields, without considering the influences of the shell thickness on their temperature sensing properties.

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Preparation of Silver Nanoparticles and Their Industrial and Biomedical Applications: A Comprehensive Review

Advances in Materials Science and Engineering ◽

10.1155/2015/165257 ◽

2015 ◽

Vol 2015 ◽

pp. 1-16 ◽

Cited By ~ 86

Author(s):

Adnan Haider ◽

Inn-Kyu Kang

Keyword(s):

Silver Nanoparticles ◽

Biomedical Applications ◽

Consumer Products ◽

Ag Nps ◽

New Techniques ◽

Governing Factor ◽

Wide Range ◽

Microbial Proliferation ◽

Synthetic Routes ◽

Biomedical Fields

Silver nanoparticles (Ag-NPs) have diverted the attention of the scientific community and industrialist itself due to their wide range of applications in industry for the preparation of consumer products and highly accepted application in biomedical fields (especially their efficacy against microbes, anti-inflammatory effects, and wound healing ability). The governing factor for their potent efficacy against microbes is considered to be the various mechanisms enabling it to prevent microbial proliferation and their infections. Furthermore a number of new techniques have been developed to synthesize Ag-NPs with controlled size and geometry. In this review, various synthetic routes adapted for the preparation of the Ag-NPs, the mechanisms involved in its antimicrobial activity, its importance/application in commercial as well as biomedical fields, and possible application in future have been discussed in detail.

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Self-assembly of Stimuli Responsive Coiled-coil Fibrous Hydrogels

Soft Matter ◽

10.1039/d1sm00780g ◽

2021 ◽

Author(s):

Michael Meleties ◽

Priya Katyal ◽

Bonnie Lin ◽

Dustin Britton ◽

Jin Kim Montclare

Keyword(s):

Drug Delivery ◽

Tissue Engineering ◽

Self Assembly ◽

Coiled Coil ◽

Stimuli Responsive ◽

Tunable Properties ◽

Stimuli Sensitive ◽

Biomedical Fields

Owing to their tunable properties, hydrogels comprised of stimuli sensitive polymers are one of the most appealing scaffolds with applications in tissue engineering, drug delivery and other biomedical fields. We...

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A Mini Review: Recent Advances in Surface Modification of Porous Silicon

Materials ◽

10.3390/ma11122557 ◽

2018 ◽

Vol 11 (12) ◽

pp. 2557 ◽

Cited By ~ 14

Author(s):

Seo Lee ◽

Jae Kang ◽

Dokyoung Kim

Keyword(s):

Surface Modification ◽

Porous Silicon ◽

Wide Spectrum ◽

Basic Research ◽

Recent Advances ◽

Developed Surface ◽

The Many ◽

Insight Into ◽

Biomedical Fields

Porous silicon has been utilized within a wide spectrum of industries, as well as being used in basic research for engineering and biomedical fields. Recently, surface modification methods have been constantly coming under the spotlight, mostly in regard to maximizing its purpose of use. Within this review, we will introduce porous silicon, the experimentation preparatory methods, the properties of the surface of porous silicon, and both more conventional as well as newly developed surface modification methods that have assisted in attempting to overcome the many drawbacks we see in the existing methods. The main aim of this review is to highlight and give useful insight into improving the properties of porous silicon, and create a focused description of the surface modification methods.

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