A research on anxiety disorder prevalence and severity among vestibuler migraine and migraine patients

2016 ◽  
Vol 33 (S1) ◽  
pp. S324-S324
Author(s):  
Ö. Kutay Yüksel ◽  
G. Akdal ◽  
T. Alkın ◽  
B. Dönmez Balcı
Keyword(s):  
Psychiatric Disorders ◽  
Trait Anxiety ◽  
Rating Scale ◽  
Separation Anxiety ◽  
Anxiety Symptoms ◽  
Depression Symptoms ◽  
Healthy Controls ◽  
Significant Difference ◽  
History Of ◽  
State Worry

In this research, anxiety, depression symptoms and severity were compared between healthy controls (HC), vestibuler migraine (VM) and migraine patients without history of vertigo (MO).MethodThirty-five definite vestibuler migraine patients (according to Neuhauser criteria), 35 MO patients and 32 healthy controls were included. All patients were evaluated for their lifetime psychiatric disorders with Structured Clinical Interview for DSM–IV/Clinical version (SCID-I/CV). All three groups evaluated by:– Hamilton Anxiety Rating Scale (HARS);– State-Trait Anxiety Inventory (STAI), (STAI-X1) and the other trait anxiety STAI-X2);– Beck depression inventory (BDI);– Lifetime Panic Agoraphobic Spectrum Scale (PAS-SR);– Penn State Worry Questionnaire (PENN);– Separation Anxiety Symptoms Inventory (SASI);– Adult Separation Anxiety Questionnaire (ASA).Psychiatric diagnosis history (SCID-I); comparison of VM and MO did not indicate a significant difference (P < 0.05). VM and MO patients were significantly different than HC in terms of anxiety symptoms in “HAM-A, PENN, ASA, PAS-SR and PAS-SR subscales (P < 0.05)”. VM was significantly different than MO patients in BDE and PAS-SR (overall; separation anxiety, agoraphobia, reassurance seeking) (P < 0.05). The longer the history of migraine the higher was the anxiety points in both in VM and MO patients (P < 0.05). Headache and vertigo severity in VM patients were significantly correlated with the elevated anxiety and depression points (P < 0.05).ConclusionVM and MO patients significantly different in anxiety and mood disorder when compared with healthy controls. Our findings showed that VM patients were more vulnerable to psychiatric disorders. For that reason, multidisciplinary approach for the treatment of VM may facilitate the treatment process.Disclosure of interestThe authors have not supplied their declaration of competing interest.

scholarly journals Comparison of nitric oxide and adrenomedullin levels of children with attention deficit hyperactivity disorder and anxiety disorder

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Yüksel Sümeyra Karagöz ◽  
Özlem Doğan ◽  
Serenay Elgün ◽  
Birim Günay Kılıç
Keyword(s):  
Nitric Oxide ◽  
Trait Anxiety ◽  
Rating Scale ◽  
Anxiety Symptoms ◽  
Control Group ◽  
Healthy Children ◽  
Children With Adhd ◽  
Significant Difference ◽  
Healthy Control ◽  
And Control

Abstract Objectives Many studies show that adrenomedullin (ADM) is associated with nitric oxide (NO) and various mechanisms and is involved in the etiopathogenesis of schizophrenia, bipolar disorder and autism by oxidative stress and HPA axis dsyregulation. The aim of this study comparison of nitric oxide and adrenomedullin levels in children with ADHD, AD and healthy control included in our study, especially due to their effect mechanisms as they may predict anxiety symptom, was to investigate the relationship between nitric oxide and adrenomedullin levels and anxiety symptoms in children with ADHD, AD and healthy control. Methods The study included 27 ADHD, 27 AD and 23 healthy children without any previous drug use, without comorbid disease. The semi-structured interview was conducted by the researcher in all the children attending the study. Sociodemographic information form, Conner’s Parent and Teacher Rating scale and State-Trait Anxiety Inventory (STAI) were evaluated. NO level measured by spectrophotometer, ADM levels were measured by ELISA. Results There was no statistically significant difference in the serum NO and ADM levels of the children included in the sampling group according to age and sex. There was no statistically significant difference between NO and ADM levels between ADHD, AD and control groups. There was no statistically significant relationship between serum NO and ADM levels and ADHD, AD and control group children of state-trait anxiety scores. Conclusions These findings may suggest that NO and ADM levels in children with ADHD, AD do not show these diseases and that these parameters are not associated with anxiety symptoms.

Clinical and demographic characteristics of psychiatric patients seropositive for Borrelia burgdorferi

2006 ◽  
Vol 21 (2) ◽  
pp. 118-122 ◽  
Author(s):  
T. Hájek ◽  
J. Libiger ◽  
D. Janovská ◽  
P. Hájek ◽  
M. Alda ◽  
...  
Keyword(s):  
Borrelia Burgdorferi ◽  
Psychiatric Disorders ◽  
Psychiatric Patients ◽  
Psychiatric Morbidity ◽  
Demographic Variables ◽  
Healthy Controls ◽  
Diagnostic Categories ◽  
Potential Association ◽  
History Of ◽  
The Central Nervous System

AbstractPurpose.Borrelia burgdorferi (Bb) infection can affect the central nervous system and possibly lead to psychiatric disorders. We compared clinical and demographic variables in Bb seropositive and seronegative psychiatric patients and healthy controls.Method.Nine hundred and twenty-six consecutive psychiatric patients were screened for antibodies to Bb and compared with 884 simultaneously recruited healthy subjects.Results.Contrary to healthy controls, seropositive psychiatric patients were significantly younger than seronegative ones. None of the studied psychiatric diagnostic categories exhibited stronger association with seropositivity. There were no differences between seropositive and seronegative psychiatric patients in hospitalization length, proportion of previously hospitalized patients and proportion of subjects with family history of psychiatric disorders.Conclusion.These findings elaborate on potential association between Bb infection and psychiatric morbidity, but fail to identify any specific clinical ‘signature’ of Bb infection.

Anxiety symptoms and suicidal feelings in a population sample of 70-year-olds without dementia

2012 ◽  
Vol 24 (11) ◽  
pp. 1865-1871 ◽  
Author(s):  
Mattias Jonson ◽  
Ingmar Skoog ◽  
Thomas Marlow ◽  
Madeleine Mellqvist Fässberg ◽  
Margda Waern
Keyword(s):  
Suicidal Behavior ◽  
Anxiety Symptom ◽  
Rating Scale ◽  
Population Sample ◽  
Symptom Burden ◽  
Late Life ◽  
Anxiety Symptoms ◽  
Psychiatric Nurses ◽  
Depression Symptoms

ABSTRACTBackground: The role of anxiety in late-life suicidal behavior has received relatively little attention. The aim was to explore the association between anxiety symptoms and suicidal feelings in a population sample of 70-year-olds without dementia, and to test whether associations would be independent of depression.Methods: Face-to-face interviews (N = 560) were carried out by psychiatric nurses and past month symptoms were rated with the Comprehensive Psychopathological Rating Scale (CPRS). The Brief Scale for Anxiety (BSA) was derived from the CPRS to quantify anxiety symptom burden. Past month suicidal feelings were evaluated with the Paykel questions.Results: Anxiety symptom burden was associated with suicidal feelings and the association remained after adjusting for major depression. One individual BSA item (Inner tension) was independently associated with suicidal feelings in a multivariate regression model. The association did not remain, however, in a final model in which depression symptoms replaced depression diagnosis.Conclusions: Results from this population study suggest an association between anxiety and suicidal feelings in older adults. The role of anxiety and depression symptoms needs further clarification in the study of suicidal behavior in late life.

scholarly journals Acupuncture Treatments for Post-stroke Depression: A Systematic Review and Network Meta-analysis

2021 ◽  
Author(s):  
Lam Wai Ching ◽  
Hui Juan Li ◽  
Jianwen Guo ◽  
Liang Yao ◽  
Janita Chau ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Rating Scale ◽  
Meta Analysis ◽  
Cochrane Library ◽  
Depression Symptoms ◽  
Post Stroke ◽  
Significant Difference ◽  
Post Stroke Depression ◽  
The Impact

Abstract Background: Depression is one of the most common complications after stroke, with a prevalence of 30-33%. Patients with post-stroke depression (PSD) usually experience anxiety, hopelessness, and insomnia, which have a negative impact on their daily activities and post-stroke rehabilitation. In this review, we aimed to explore the impact of acupuncture in alleviating symptoms of PSD and to evaluate the difference in effectiveness between acupuncture combined with pharmacotherapies and various non-pharmacotherapies in order to provide guides and advice for clinical personnel. Methods: Six databases (Cochrane Library, PubMed, EMBASE, China National Knowledge Infrastructure, Wanfang Database, Chongqing VIP Database) and two clinical trials registration platforms were searched from inception to May 2021. Randomized clinical trials (RCTs) comparing needle-based acupuncture with pharmacotherapy, and other non-pharmacotherapy or invalid group were included. Two independent reviewers identified eligible studies. Two reviewers independently abstracted and recorded data into a pre-made form. A Bayesian network meta-analysis (NMA) was conducted to assess and compare different techniques using RStudio 3.6.0. The primary outcome was the change in scores of scales measuring depressive symptoms. The secondary outcomes were changes in serotonin levels and in quality of life. Results: Fifty-nine RCTs were included. The results of this NMA showed that compared with western medicine (WM), acupuncture alone or with repetitive transcranial magnetic stimulation (RTMS), Traditional Chinese medicine (TCM) alone or with WM, were superior for alleviating depression symptoms. Compared to Usual Care, acupuncture alone or plus other therapies could significantly decrease scores of the Hamilton Depression Rating scale. However, there was no significant difference found among acupuncture, WM, TCM with AC plus any of other treatment.Conclusions: The results of this study indicate that acupuncture alone or combined with other therapies appear to be effective in improving depression symptoms of stroke survivors. Moreover, in comparison with WM, acupuncture alone or plus RTMS, TCM, TCM with WM, or WM, were more effective in improving depression symptoms. Also, acupuncture with RTMS seems to be the most effective with the highest probability.

scholarly journals Evaluation of the Fun FRIENDS program with a sample of Mexican children

2020 ◽  
Vol 16 (1) ◽  
pp. 1-21
Author(s):  
Julia Gallegos-Guajardo ◽  
Norma A. Ruvalcalba-Romero ◽  
Ania Chávez-Amavizca ◽  
Paula Barrett
Keyword(s):  
Intervention Program ◽  
Protective Factor ◽  
Rating Scale ◽  
Separation Anxiety ◽  
First Grade ◽  
Anxiety Symptoms ◽  
Negative Consequences ◽  
Mexican Children ◽  
Quasi Experimental ◽  
Children’S Anxiety Symptoms

Introduction: Anxiety symptoms in young children can have negative consequences such as the deterioration of family and interpersonal functioning, and may lead to the development of an anxiety disorder; therefore, the importance of prevention. Objective: The aim of this study was to evaluate the effectiveness of the Fun FRIENDS program in the reduction of children’s anxiety symptoms and the promotion of emotional and behavioral competences as a protective factor in a sample of Mexican children. Methodology: The participants included 49 children from the first grade at elementary school along with their teachers. The program was implemented by teachers as twelve consecutive one-week sessions conducted in the classroom. The outcome was measured with a pretest-posttest quasi-experimental design. Measures included the Preschool Anxiety Scale (PAS), for parents, Behavioral and Emotional Rating Scale (BERS-2), for parents, and Strengths and Difficulties Questionnaire (SDQ), for parents and teachers. Results: Findings showed a decrease in the subscale of separation anxiety of the PAS, an increase in the interpersonal, intrapersonal and affective strengths subscales of the BERS-2, and an increase in prosocial behavior as measured by the SDQ. Conclusions: Results indicate promise for the effectiveness of the Fun FRIENDS program as an early intervention program based on the promotion of resilience for Mexican children.

scholarly journals 156 Improvement in Disease Severity in Patients With Treatment-Resistant Depression Following Treatment With Intranasal Esketamine

CNS Spectrums ◽  
2018 ◽  
Vol 23 (1) ◽  
pp. 95-96
Author(s):  
Abigail Nash ◽  
May Shawi ◽  
Jaskaran Singh ◽  
Ella Daly ◽  
Kimberly Copper ◽  
...  
Keyword(s):  
Large Scale ◽  
Rating Scale ◽  
Depression Symptoms ◽  
Inadequate Response ◽  
P Values ◽  
Weekly Treatment ◽  
Patient Reported ◽  
History Of ◽  
Reported Data ◽  
Psychotic Features

AbstractBackgroundRecognizing the importance not only of the clinician’s opinion but also of the patient’s experience and perspective, Sequenced Treatment Alternatives to Relieve Depression (STAR*D) utilized both clinician-reported and patient-reported outcomes in a large-scale multi-step study on antidepressant effectiveness in real-world settings. Both approaches indicate that <17% of Major Depressive Disorder (MDD) patients respond to novel oral treatments after two prior antidepressant failures. To address this low response rate and continue to investigate the use of patient-rated outcomes in clinical trials, an antidepressant with a new mechanism of action is being investigated for efficacy and safety utilizing both clinician-rated and patient-reported scales.MethodsThis is a post-hoc analysis of a Janssen R&D Phase 2a clinical trial (ESKETINTRD2003). Subjects aged 20-64 withMDD without psychotic features (DSM IV) and a history of inadequate response to ≥2 antidepressants were randomized [3:1:1:1] to 1 week of twice-weekly treatment with intranasal placebo (n=33), esketamine 28 mg (n=11), 56 mg (n=11), or 84 mg (n=12). Participants taking oral antidepressants at study entry continued treatment during the study. Changes in depression severitywere measured using the Clinical Global Impression Severity (CGI-S) and the Patient Global Impression Severity (PGI-S) scales.ResultsAt all esketamine doses (28 mg, 56 mg, 84 mg), subjects reported a one-point mean change in PGI-S from baseline to week one compared to no change on placebo (p-values 0.005, 0.001, 0.032 respectively). Similarly, mean CGI-S scores improved for subjects receiving esketamine at all doses (p-values 0.028, 0.004, 0.049 respectively) compared to no change inplacebo subjects. These data are consistent with previously reported data based on the Montgomery Åsberg Depression Rating Scale (MADRS) and support positive correlation between patient-reported and clinician-reported outcomes.DiscussionInitial results from this Phase 2a study suggest clinically relevant improvement in depression symptoms in as early as one week when treated with twice-weekly intranasal esketamine as reported by both clinicians and patients. This work will help guide future investigations of esketamine in larger populations to provide better therapeutic options for treatment resistantMDD patients.Funding AcknowledgementsJanssen

Screening for Anxiety Symptoms in Parkinson Disease

2013 ◽  
Vol 26 (1) ◽  
pp. 34-40 ◽  
Author(s):  
Elka Stefanova ◽  
Ljubomir Ziropadja ◽  
Mirjana Petrović ◽  
Tanja Stojković ◽  
Vladimir Kostić
Keyword(s):  
Parkinson Disease ◽  
Convergent Validity ◽  
Rating Scales ◽  
Rating Scale ◽  
Anxiety Symptoms ◽  
Depression Symptoms ◽  
Consecutive Series ◽  
Clinical Markers ◽  
Cognitive Screening ◽  
Levodopa Dose

Background: A limited number of studies examined anxiety in Parkinson disease (PD). Questionable validity of the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) defined anxiety disorders in PD population as well as a lack of validated rating scales hampered the investigation in this field. Objective: To screen for prevalence of anxiety symptoms and their associated demographic and clinical features in an outpatient-based cohort with PD. Patients and methods: A consecutive series of 360 patients with PD underwent investigation with the Hamilton Anxiety Rating Scale (HARS), the 17-item Hamilton Depression Rating Scale, Neuropsychiatric Inventory, section E (anxiety), motor scoring with Hoehn and Yahr staging, the Unified Parkinson’s Disease Rating Scale, and cognitive screening with the Mini-Mental State Examination. Results: In all, 136 (37.8%) patients with PD of our cohort had anxiety symptoms, whereas both depression and anxiety were recorded in 5.6% of the patients, while in 56.7% neither anxiety nor depression was present. Female gender, motor disability, and core depression symptoms were the main markers of anxiety in patients with PD. The severity of anxiety symptoms was not associated with asymmetry of motor symptoms. Education, disease duration, and levodopa dose were poor predictors in the model. The HARS had a satisfactory inter-item correlation, convergent validity, and factorial structure. Conclusions: Anxiety may be present as an isolated symptom, with specific demographic and clinical markers, and not only as a feature of depression in PD population. This highlighted the importance of identifying anxiety symptoms when treating patients with PD.

scholarly journals Psychological Status of High School Students 1 Year After the COVID-19 Emergency

2021 ◽  
Vol 12 ◽  
Author(s):  
Cong Zhou ◽  
Rongqin Li ◽  
Mingchuan Yang ◽  
Shanshan Duan ◽  
Chuanming Yang
Keyword(s):  
High School ◽  
High School Students ◽  
Sleep Disturbances ◽  
Rating Scale ◽  
Sleep Problems ◽  
Anxiety Symptoms ◽  
Psychological Status ◽  
Depression Symptoms ◽  
Cross Sectional Survey ◽  
School Students

Background: With the control of the epidemic, adolescents' mental outlook might have improved. However, little evidence existed with regard to the psychological status of adolescents in post-COVID-19 era. This present study aimed to explore the psychological status of high school students after the epidemic getting eased.Methods: A web-based cross-sectional survey was used to obtain data from three high schools, including the demographic information, the Patient Health Questionnaire-9 (PHQ-9), the Generalized Anxiety Disorder-7 (GAD-7), the Self-Rating Scale of Sleep (SRSS), and self-designed general recent-status questionnaire. Correlation analysis was performed to explore potential associations between the depression symptoms, anxiety symptoms, and sleep status. The PHQ-9 and GAD-7 differences between nowadays data and the data enrolled 12 months before were also compared.Result: A total of 1,108 qualified questionnaires were obtained. The prevalence of depressive and anxious symptoms was 27.5 and 21.3%, respectively, from mild to severe in all students, while 11.8% of these high students got sleep disturbances. Both the rate and the severity of depression, anxiety and sleep problems of female students were higher than male students. Grade three students suffered higher prevalence and severer mental disturbances than the other two grades. There were significant correlations between the depression symptoms, anxiety symptoms, and sleep status. The psychological status has been improved in nowadays high school students compared with the sample enrolled 12 months before.Conclusion: As a supplement to our former study, this present research provided a perspective on the psychological status of high school students 1 year after the COVID-19 pandemic being well controlled. We should pay attention to the psychological status of high school students, and should also notice the progresses made by this special group after the epidemic.

scholarly journals Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Fushui Liu ◽  
Ting Fang ◽  
Fanyuan Zhou ◽  
Meimei Zhao ◽  
Mei Chen ◽  
...  
Keyword(s):  
Neck Pain ◽  
Meta Analysis ◽  
Statistical Significance ◽  
Anxiety Symptoms ◽  
Healthy People ◽  
Depression Symptoms ◽  
Controlled Trials ◽  
High Morbidity ◽  
Significant Difference ◽  
Anxiety Depression

Background. Due to its high morbidity and prevalence, the potential relationships of depression/anxiety symptoms in neck pain (NP) are not well demonstrated. Objectives. This study aimed to conduct a comprehensive estimation of controlled trials of psychological problems and to test hypotheses concerning whether NP was statistically relative to anxiety/depression symptoms. Methods. Chinese literature databases such as the China National Knowledge Infrastructure (CNKI), VIP Information (VIP), Chinese Biomedicine (CBM), and Wanfang Data (WANFANG) were scientifically searched for reports published until February 5, 2018. Controlled trials incorporating NP patients with anxiety/depression versus healthy people were contained. Two researchers screened each article and extracted data, respectively, and blinded to the findings of each other. Meta-analysis was conducted by the Cochrane Collaboration’s RevMan 5.3 and Stata 14.0 (Stata Corp LP, USA) software. Results. We identified 13 eligible studies involving 2339 patients and 3290 healthy people. Compared with healthy control participants, the findings indicated that depression/anxiety symptoms were more common or severe in NP patients (respectively, SMD = 0.89; 95% CI = (0.58, 1.20); P<0.01 and SMD = 0.92; 95% CI = (0.65, 1.20); and P<0.01), results from the pooled data demonstrated no statistical significance between depression/anxiety symptoms and gender in NP patients (resp., SMD = 0.16; 95% CI = (−0.18, 0.51); P=0.35 and SMD = −0.08; 95% CI = (−0.42, 0.27); and P=0.67), and the combined data of the incidence of depression or anxiety symptoms revealed significant difference between NP patients and healthy persons (resp., RR = 4.81; 95% CI = (3.30, 7.01); P<0.01 and RR = 3.29; 95% CI = (2.16, 5.00); and P<0.01). In addition, we did not find articles that met the inclusion criteria, which compared NP patients with other physical illnesses in terms of anxiety/depression symptoms. Conclusions. This meta-analysis suggests that anxiety/depression symptoms are associated with high morbidity in NP patients. We consider these reports support the viewpoint that nonspecific mechanisms mediate mental disturbances in NP. This study may have clinical value for NP, offering an underlying target for the prevention and treatment of anxiety/depression.

scholarly journals Influence of Family Environment on Childhood Emotional and Behavioural Disorders

2020 ◽  
Vol 7 (44) ◽  
pp. 2544-2549
Author(s):  
Ganga G. Kaimal ◽  
Varghese P. Punnoose ◽  
Saibunnisa Beevi K
Keyword(s):  
Family History ◽  
Psychiatric Disorders ◽  
Emotional Disorders ◽  
Family Environment ◽  
Psychiatric Illness ◽  
Family Type ◽  
Behavioural Disorders ◽  
Child Psychiatric ◽  
Significant Difference ◽  
History Of

BACKGROUND India has a large proportion of child and adolescent population. Psychiatric disorders are common among children and adolescents, but they are often underdiagnosed. Family environment influences psychopathology in young children. Identification of risk factors for child psychiatric disorders can lead to early identification of children at risk and facilitation of preventive interventions. METHODS The study was conducted among 103 children attending the Child Guidance Clinic (CGC) in a tertiary care institute in Kerala. A specially prepared proforma was used to obtain the sociodemographic profile and clinical variables. Global Family Environment Scale was used to assess the quality of family environment. ICD 10 classification of mental and behavioural disorders was used for making diagnosis, and Ravens Coloured Progressive Matrices was used for assessing intelligence. RESULTS Emotional disorders were seen more commonly in girls, and in older age group. Children with behavioural disorders were below average in academics and the difference between the groups was statistically significant. No statistically significant difference was found between the groups in socioeconomic status, locality, family type, family history of psychiatric illness, and in family environment. CONCLUSIONS Though there was no statistically significant difference, family history of psychiatric illness and poor and moderately unsatisfactory family environment was observed in a large proportion of children. This finding may have implication in management of childhood psychiatric disorders. KEYWORDS Family Environment, Children, Emotional Disorders, Behavioural Disorders

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