Deciphering the effects of genetic characteristics and environmental factors on pharmacological active ingredients of Eucommia ulmoides

2022 ◽  
Vol 175 ◽  
pp. 114293
Author(s):  
Chunbo Dong ◽  
Zhiyuan Zhang ◽  
Qiuyu Shao ◽  
Ting Yao ◽  
Haiyan Hu ◽  
...  
Keyword(s):  
Environmental Factors ◽  
Eucommia Ulmoides ◽  
Active Ingredients ◽  
Genetic Characteristics

REACTION OF SPRING WHEAT LINES WITH FOREIGN GENETIC MATERIAL TO THE IMPACT OF ARTIFICIALLY CREATED STRESSES

2021 ◽  
Author(s):  
O. V. Pavlova ◽  
◽  
L. A. Marchenkova ◽  
R. F. Chavdar ◽  
T. G. Orlova ◽  
...  
Keyword(s):  
Sodium Chloride ◽  
Environmental Factors ◽  
Spring Wheat ◽  
Genetic Material ◽  
Growth Processes ◽  
Genetic Characteristics ◽  
Early Stages ◽  
Inhibition Of Growth ◽  
Wheat Lines ◽  
The Impact

The adaptive properties of spring wheat lines with foreign genetic material at the early stages of ontogenesis on the backgrounds of salinization with sodium chloride and prolonged flooding of seeds in water were evaluated. In the course of the work, different degrees of inhibition of growth processes were revealed, depending on the factor used and the genetic characteristics of the studied forms, a comprehensive (summary) assessment of the index of stability characterizing adaptability to adverse environmental factors was shown.

Mitochondrial haplogroups in Basque multiple sclerosis patients

2004 ◽  
Vol 10 (5) ◽  
pp. 532-535 ◽  
Author(s):  
D Otaegui ◽  
A Sáenz ◽  
M Martínez-Zabaleta ◽  
P Villoslada ◽  
I Fernández-Manchola ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Mitochondrial Dna ◽  
Risk Factor ◽  
Environmental Factors ◽  
Optic Neuritis ◽  
Basque Country ◽  
Mitochondrial Haplogroups ◽  
Genetic Characteristics ◽  
Mitochondrial Haplogroup ◽  
Multiple Sclerosis Patients

Previous studies have suggested that mitochondrial metabolism and/or mitochondrial DNA (mtDNA) could be, in conjunction with other genetic or environmental factors, a risk factor for the development of multiple sclerosis (MS). One of these studies establishes that mitochondrial haplogroup JT is a risk factor for developing the disease, in particular the visual manifestations [optic neuritis (ON)]. Nevertheless, as distribution of these haplogroups varies between populations, the observed association may be due to a slanted sample with no physiopathological value. This hypothesis was checked with MS patients, originals from Basque country (this population has peculiar genetic characteristics) and from other Spanish regions. We concluded that such an association does not exist. By contrast, a decrease could be seen in the frequency of the JT haplogroup in the ON group and in the MS-Basque group. That trend could be a protective effect, which needs to be verified in further investigations.

Screening of anti-complement active ingredients from Eucommia ulmoides Oliv. branches and their metabolism in vivo based on UHPLC-Q-TOF/MS/MS

2019 ◽  
Vol 1124 ◽  
pp. 26-36 ◽  
Author(s):  
Jia Jia ◽  
Mi Liu ◽  
Quan Wen ◽  
Mingzhen He ◽  
Hui Ouyang ◽  
...  
Keyword(s):  
Eucommia Ulmoides ◽  
Active Ingredients ◽  
Tof Ms

The Role of Traffic-Related Air Pollution on Neurodegenerative Diseases in Older People: An Epidemiological Perspective

2020 ◽  
pp. 1-11
Author(s):  
Rachel Tham ◽  
Tamara Schikowski
Keyword(s):  
At Risk ◽  
Air Pollution ◽  
Environmental Factors ◽  
Neurodegenerative Diseases ◽  
Risk Groups ◽  
Air Pollutant ◽  
The Body ◽  
Design Assessment ◽  
Genetic Characteristics

Traffic-related air pollution is ubiquitous and almost impossible to avoid. It is important to understand the role that traffic-related air pollution may play in neurodegenerative diseases, such as dementia, Alzheimer’s disease, and Parkinson’s disease, particularly among older populations and at-risk groups. There is a growing interest in this area among the environmental epidemiology literature and the body of evidence identifying this role is emerging and strengthening. This review focuses on the principal components of traffic-related air pollutants (particulate matter and nitrogen oxides) and the epidemiological evidence of their contribution to common neurodegenerative diseases. All studies reported are currently observational in nature and there are mixed findings depending on the study design, assessment of traffic-related air pollutant levels, assessment of the neurodegenerative disease outcome, time period of assessment, and the role of confounding environmental factors and at-risk genetic characteristics. All current studies have been conducted in income-rich countries where traffic-related air pollution levels are relatively low. Additional longer-term studies are needed to confirm the levels of risk, consider other contributing environmental factors and to be conducted in settings where air pollution exposures are higher and at-risk populations reside and work. Better understanding of these relationships will help inform the development of preventive measures and reduce chronic cognitive and physical health burdens (cost, quality of life) at personal and societal levels.

scholarly journals Insights Into the Environmental Impact on Genetic Structure and Larval Dispersal of Crown-of-Thorns Starfish in the South China Sea

2021 ◽  
Vol 8 ◽  
Author(s):  
Biao Chen ◽  
Kefu Yu ◽  
Qiucui Yao ◽  
Zhiheng Liao ◽  
Zhenjun Qin ◽  
...  
Keyword(s):  
Genetic Diversity ◽  
Genetic Structure ◽  
Environmental Factors ◽  
South China Sea ◽  
Larval Dispersal ◽  
Population Expansion ◽  
Convergence Region ◽  
Genetic Characteristics ◽  
The Pacific ◽  
The Pacific Ocean

The coral-eating crown-of-thorns starfish (COTS; Acanthaster spp.) play a major role in coral reef degradation in the Indo-Pacific region. However, the impacts of environmental factors on the phylogenetic and genetic characteristics of COTS in the northern Indo-Pacific convergence region remains unclear. We used mitochondrial DNA (mtDNA) and microsatellite markers to analyze the phylogenetic relationship, demographic history, genetic diversity and genetic structure of COTS in the South China Sea (SCS) and explored the impact of environmental factors on historical population expansion, genetic differentiation and larval dispersal. There was a clear signature of a population expansion in the SCS using the mtDNA marker. According to microsatellite loci analysis, COTS have high genetic diversity in the SCS. STRUCTURE analysis indicated that COTS in the Pacific Ocean can be divided into four subgroups: the SCS, Western Pacific, Pacific equatorial current affected zone, and Pacific insular atolls populations in the Pacific Ocean. Fst-statistical analysis revealed positive correlations between the Fst values and geographic isolation for all sampling sites. Additionally, there were no clear associations between the Fst values and chlorophyll a concentrations among coral reefs in the SCS; however, there were significant positive associations between the Fst values and particulate organic carbon (POC) concentrations within small geographic distances. These results suggest that COTS underwent historical population expansion after the Last Glacial Maximum, possibly followed by coral population expansion. The genetic structure of COTS populations may have been shaped by distinct nutrient concentrations, particularly those of POC, over small geographic distances. Moreover, ocean currents provide a potential dispersal mechanism for COTS larvae in the SCS. This study demonstrates that environmental and oceanographic factors play important roles in shaping the genetic characteristics and larval dispersal of COTS populations in the northern Indo-Pacific convergence region.

scholarly journals Modern understanding of the pathogenesis of basal cell skin cancer

2021 ◽  
Vol 97 (5) ◽  
pp. 38-51
Author(s):  
R. R. Saytburkhanov ◽  
A. A. Kubanov ◽  
I. N. Kondrakhina ◽  
X. I. Plakhova
Keyword(s):  
Skin Cancer ◽  
Environmental Factors ◽  
Basal Cell ◽  
Hedgehog Signaling ◽  
Web Of Science ◽  
Morphological Structure ◽  
Response To Treatment ◽  
Hedgehog Signaling Pathway ◽  
Tumor Resistance ◽  
Genetic Characteristics

The incidence of basal cell skin cancer is increasing worldwide. The initiation and progression of basal cell skin cancer is due to the interaction of environmental factors and the patient's genetic characteristics. Aberrant activation of the transmission of the Hedgehog signaling pathway is the main pathogenetic pathway of carcinogenesis. Since basal cell skin cancer is manifested by significant variability of morphological structure, aggressiveness and response to treatment, the disclosure of the molecular genetics of pathogenesis will become the basis for developing new approaches and increasing the effectiveness of treatment, as well as overcoming tumor resistance to treatment. To search for the necessary literature, the PubMed, MedLine, Web of Science and RSCI databases were used.

scholarly journals Effect of physico-morphic characters and environmental factors on infestation of thrips (Thrips tabaci) on five onion cultivars

2020 ◽  
Vol 4 (1) ◽  
Author(s):  
Ajmal Hussain ◽  
Humayun Javed ◽  
Khadija Javed ◽  
Muhammad Hanif
Keyword(s):  
Environmental Factors ◽  
Adult Population ◽  
Maximum Yield ◽  
Thrips Tabaci ◽  
Economic Returns ◽  
Genetic Characteristics ◽  
Average Temperature ◽  
Average Relative Humidity ◽  
Positive Correlations ◽  
Thrips Population

Resistance to plants is frequently associated with physical, morphological, physiological, biochemical, molecular and genetic characteristics of the plants. As very little information is available on the effects of physico-morphic characteristics and environmental factors on thrips (Thrips tabaci) infestation, therefore, in the present study such effects were evaluated on the infestation of thrips on five onion cultivars. Maximum number of adults and infestation of thrips was recorded on Marvi followed by Golden Orb while the adults and infestation was the minimum on Red Orb. Significant variations were observed in plant heights and girths among five onion varieties after 40, 70 and 100 days. Similarly, maximum yield was observed in case of Red Orb followed by F1 Mustang while the minimum yield was obtained with cultivar Marvi. The low temperature, high temperature and average temperature showed significant and positive correlations among all the cultivars. However, the average relative humidity showed negative and non-significant correlation for all the varieties. The correlation between physico-morphic characteristics and adult population was found significant for plant girth after 40 days while the correlations were non-significant for all the other factors. It is concluded from the present studies that Red Orb is comparatively resistant cultivar harboring the minimum thrips population. The highest yield was also recorded in case of Red Orb as compared to other tested cultivars and recommended for cultivation to enhance economic returns of farmers.

scholarly journals Fatty Acids Variation in Seed of Eucommia ulmoides Populations Collected from Different Regions in China

Forests ◽  
2018 ◽  
Vol 9 (9) ◽  
pp. 505 ◽  
Author(s):  
Qingxin Du ◽  
Lu Wang ◽  
Panfeng Liu ◽  
Jun Qing ◽  
Caowen Sun ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Environmental Factors ◽  
Linolenic Acid ◽  
Oil Content ◽  
Seed Oil ◽  
Principal Component ◽  
Mass Spectrometry Analysis ◽  
Gas Chromatography Mass Spectrometry ◽  
Eucommia Ulmoides ◽  
Geographical Regions

Fruits of 240 Eucommia ulmoides Oliver individuals were collected from 12 different geographical regions across a wide area of China. The seed oil content ranged from 28.54% in Guilin and Lueyang to 31.35% in Chaoyang. Gas chromatography–mass spectrometry analysis of the seed oil revealed that linolenic acid (56.68–60.70%), oleic acid (16.31–17.80%), and linoleic acid (11.02–13.32%) were the major components, and the oil showed good potential for the food and health care industries. Three levels (high, medium, and low) of linolenic acid and oil content were observed among the 12 populations according to principal component analysis. Canonical correspondence analysis showed that environmental factors had a large influence on oil content and fatty acids composition and explained 89.33% of the total variance. Latitude and precipitation were key environmental factors and were significantly correlated with the fatty acid composition of E. ulmoides seeds.

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