scholarly journals Moderate coffee consumption is inversely associated with the metabolic syndrome in the Korean adult population

2018 ◽  
Vol 120 (11) ◽  
pp. 1279-1287 ◽  
Author(s):  
Youngyo Kim ◽  
Youjin Je
Keyword(s):  
Metabolic Syndrome ◽  
Linear Trend ◽  
Adult Population ◽  
Coffee Consumption ◽  
Obese People ◽  
Coffee Intake ◽  
Significant Positive Association ◽  
Significant Linear Trend ◽  
The Metabolic Syndrome ◽  
Obesity Status

AbstractResults from studies investigating the association between coffee consumption and the metabolic syndrome in Koreans have been inconsistent and remain controversial. We examined coffee intake in relation to the metabolic syndrome using data from the Korea National Health and Nutrition Examination Survey 2012–2015, with 8387 adults aged 19–64 years. Furthermore, we conducted a stratified analysis by obesity status (BMI <25 v. ≥25 kg/m2) to examine whether the association varied by obesity status. A 112-item FFQ was used to assess diet. Multivariable logistic regression models were used to determine the association of coffee consumption (<1, 1–2, 3–4 and ≥5 times/d) and the metabolic syndrome. Compared to people who consumed <1 time/d of coffee, the OR for the metabolic syndrome in those who consumed 3–4 times/d of coffee was 0·75 (95 % CI 0·58, 0·97). However, ≥5 times/d of coffee consumption was not significantly associated with the metabolic syndrome. By obesity status, in non-obese people, those consuming more coffee had lower odds of the metabolic syndrome, showing a significant linear trend (P-trend=0·0248). In obese people, the OR for the metabolic syndrome in people with 3–4 times/d of coffee consumption v. <1 time/d was 0·68 (95 % CI 0·50, 0·93), but ≥5 times/d of coffee consumption showed a non-significant positive association. Our findings suggest that moderate coffee consumption of 3–4 times/d is inversely associated with the metabolic syndrome in Korean adults. The association between heavy coffee consumption of ≥5 times/d and the metabolic syndrome varied by obesity status.

scholarly journals Risk factors associated with the metabolic syndrome in Cali, Colombia (2013): A case-control study

Biomédica ◽  
2019 ◽  
Vol 39 (1) ◽  
pp. 46-54 ◽  
Author(s):  
Sayda Milena Pico ◽  
Gustavo Bergonzoli ◽  
Adolfo Contreras
Keyword(s):  
Metabolic Syndrome ◽  
Linear Trend ◽  
Adult Population ◽  
World Health ◽  
Diabetes Mellitus Type Ii ◽  
Factors Associated ◽  
The Metabolic Syndrome ◽  
Total Prevalence ◽  
Low Hdl ◽  
Health Organization

Introduction: In 2016, the World Health Organization reported that more than 2 billion adults were overweight, of whom 600 million were obese, 347 million had diabetes mellitus type II, and people with hypertension had increased from 600 million in 1980 to 1 billion in 2010. Additionally, 20% of the world’s adult population will develop metabolic syndrome during their lifespan with tremendous effects for their wellbeing and the health systems. Objective: To identify social, biological, and behavioral factors associated with the metabolic syndrome in adults to help in the design of health policies in urban environments.Materials and methods: We included 300 cases and 675 controls. For cases, the waist circumference (abdominal obesity) in men was ≥94 cm and ≥88 cm in women, and other two factors should be present including hypertension, high glycated hemoglobin, high triglycerides, and low HDL levels. Controls presented only one or none of these risk factors.Results: The total prevalence of metabolic syndrome was 30.2%, 33.6% in females, and 25.6% in males. Therefore, females had a higher risk of developing a metabolic syndrome (OR=1.70; 95% CI 1.17-2.47). Being a mestizo also increased the risk of having metabolic syndrome (OR=1.55; 95% CI 1.10-2.19). In contrast, frequent fruit consumption and being a housekeeper were protective factors: OR=0.83; 95% CI 0.69-1.00, and OR=0.58; 95% CI 0.36-0.92, respectively. Logistic regression showed that obesity had the strongest association with metabolic syndrome (OR=7.52; 95% CI 4.79-11.80). Increasing age yielded a linear trend with regard to metabolic syndrome: the OR for the 40 to 49-year-old group was 4.24 (95% CI 2.20-8.16), for the 50 to 59-year-old group, 4.63 (95% CI 2.40-8.93), and for those over 80 years of age, 5.32 (95% CI 1.92-14.71).Conclusion: Obesity was the main risk factor associated with the metabolic syndrome. Our findings can help health policy makers to design interventions for metabolic syndrome control in urban populations in Colombia.

The Association Between Uric Acid and Hepatic Function Markers With the Metabolic Syndrome in Middle-aged, Overweight, and Obese People

2010 ◽  
Vol 20 (6) ◽  
pp. 312-315
Author(s):  
Angelos A. Evangelopoulos ◽  
Natalia G. Vallianou ◽  
Demosthenes B. Panagiotakos ◽  
Aikaterini T. Georgiou ◽  
Georgios A. Zacharias ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Hepatic Function ◽  
Middle Aged ◽  
Obese People ◽  
The Metabolic Syndrome

scholarly journals Inflammation, obesity and comorbidities: the role of diet

2007 ◽  
Vol 10 (10A) ◽  
pp. 1164-1172 ◽  
Author(s):  
Mónica Bulló ◽  
Patricia Casas-Agustench ◽  
Pilar Amigó-Correig ◽  
Javier Aranceta ◽  
Jordi Salas-Salvadó
Keyword(s):  
Metabolic Syndrome ◽  
Virgin Olive Oil ◽  
Plasminogen Activator Inhibitor ◽  
Overweight And Obesity ◽  
Factor Vii ◽  
Processed Meat ◽  
Obese People ◽  
Metabolic Complications ◽  
The Metabolic Syndrome ◽  
Increased Risk

AbstractThe adipocyte metabolism has been shown to change during the fat enlargement process associated to obesity. Several procoagulant proteins such as plasminogen activator inhibitor type 1, tissue factor or factor VII and also inducible nitric oxide synthase show higher expression in adipose tissue of obese people in comparison to lean. This overexpression could explain at least a part of the atherogenic and cardiovascular risk associated with obesity.In addition to cytokine secretion, many other features have been observed to be common to adipocyte and monocyte/macrophage lines: for example, phagocytic and microbicidal activities, and possibly a cellular plasticity of adipose precursors.Overweight and obesity are associated with an increased risk of such metabolic abnormalities as dyslipidemia, hypertension or type 2 diabetes mellitus and cardiovascular diseases, common features of the metabolic syndrome. Initially, insulin resistance or hyperinsulinemia was suggested as the origin of these abnormalities. More recent studies indicate that adipokynes have an important role in obesity-associated metabolic complications, and suggest that chronically elevated local or systemic concentrations of adipokynes contribute to the development of complications associated with obesity and metabolic syndrome.Considering all the evidence relating to diet and inflammation, the best diet for protecting against the metabolic derangements associated with obesity and metabolic syndrome would be high in fibre-rich cereals, fruit, vegetables, fish, virgin olive oil and nuts; moderate in wine; and low in meat, processed meat foods and trans-fatty acids.

scholarly journals Association of Dietary and Lifestyle Inflammation Score With Metabolic Syndrome in a Sample of Iranian Adults

2021 ◽  
Vol 8 ◽  
Author(s):  
Fatemeh Dehghani Firouzabadi ◽  
Ahmad Jayedi ◽  
Elaheh Asgari ◽  
Zahra Akbarzadeh ◽  
Nasim Janbozorgi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Adult Population ◽  
Positive Association ◽  
Population Based ◽  
Cross Sectional Study ◽  
Significant Positive Association ◽  
Cross Sectional ◽  
General Adult Population ◽  
Education Status ◽  
Inflammation Score

Objective: We aimed to evaluate the association between the dietary and lifestyle inflammation score (DLIS) and metabolic syndrome (MetS) and its components in a sample of Iranian adults.Design: Population-based cross-sectional study.Setting: General adult population living in Tehran, Iran.Subjects: We included 827 adult men and women with an age range of 18–59 years who were referred to health centers in different districts of Tehran, Iran. Dietary intake was assessed by a semiquantitative food frequency questionnaire with 168 items. The DLIS was calculated based on four components, including dietary inflammation score, physical activity, cigarette smoking, and general obesity. Higher DLIS represents a more proinflammatory diet and lifestyle. The odds ratio (OR) and 95% confidence interval (CI) of the MetS across quartiles of the DLIS was calculated by using logistic regression analysis, controlling for age, sex, energy intake, marital status, education status, and occupation.Results: A total of 827 participants (31% men) were included, with a mean age of 44.7 ± 10.7 years. The prevalence of the MetS was 30.5%. The DLIS ranged between −2.35 and +3.19 (mean ± SD: 0.54 ± 1.09). There was a significant positive association between the DLIS and odds of MetS (OR fourthvs.thefirstquartile: 1.57, 95% CI: 1.01–2.45) in the fully adjusted model.Conclusion: Our results showed a significant positive association between the DLIS and odds of MetS. The results of the present crosssectional study suggested that having a more proinflammatory lifestyle can be associated with MetS. More prospective studies are needed to confirm the findings.

scholarly journals Prevalence of Obesity and Metabolic Syndrome in Adult Population of Selected Regions of the Czech Republic. Relation to Eating Habits and Smoking

2012 ◽  
Vol 113 (3) ◽  
pp. 206-216 ◽  
Author(s):  
Michala Vosátková ◽  
J. Čeřovská ◽  
H. Zamrazilová ◽  
P. Hoskovcová ◽  
M. Dvořáková ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Body Mass Index ◽  
Czech Republic ◽  
Body Mass ◽  
Eating Habits ◽  
Adult Population ◽  
Total Sample ◽  
Female Group ◽  
The Czech Republic ◽  
The Metabolic Syndrome

Prevalence of the metabolic syndrome is around 25% in Europe but its occurrence grows in both genders with increasing age and weight. Lifestyle factors may contribute to the risk of developing metabolic syndrome. The objective of this study was to determine the relationship between metabolic syndrome and eating habits as well as length of sleep and smoking. Participants (519 women and 286 men aged 18–65 years) were chosen by random selection and questioned about their eating habits, sleep length and smoking. This information was combined with anthropometric and clinical parameters of metabolic syndrome. The female group was divided into two subgroups depending on climacteric stage (before and after menopause). Metabolic syndrome prevalence does not differ between regions in neither female (29.9%) nor male (32.5%) group. Body mass index ≥25 was detected in 50.4% of all women and 65.7% of men; 23.5% of all women and 21.7% men had body mass index ≥30. In conclusion, metabolic syndrome prevalence was proved to depend on eating habits and family heredity. Positive correlation between the above mentioned factors demonstrated itself in the total sample but not in individual regions. Metabolic syndrome prevalence in Czech adults is comparable with neighbouring countries. No significant interregional differences in metabolic syndrome prevalence within the Czech Republic were detected. In conclusion, relationship between eating habits and metabolic syndrome was confirmed.

Hypertension in Metabolic Syndrome: Novel Insights

2020 ◽  
Vol 16 (1) ◽  
pp. 12-18 ◽  
Author(s):  
Alexandra Katsimardou ◽  
Konstantinos Imprialos ◽  
Konstantinos Stavropoulos ◽  
Alexandros Sachinidis ◽  
Michalis Doumas ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Adult Population ◽  
Renin Angiotensin System ◽  
Channel Blockers ◽  
Cvd Risk ◽  
The Metabolic Syndrome ◽  
Drug Classes ◽  
High Prevalence ◽  
Metabolic Properties ◽  
Obesity Hypertension

Background: Metabolic syndrome (MetS) is characterized by the simultaneous presence of obesity, hypertension, dyslipidemia and hyperglycemia in an individual, leading to increased cardiovascular disease (CVD) risk. It affects almost 35% of the US adult population, while its prevalence increases with age. Elevated blood pressure is the most frequent component of the syndrome; however, until now, the optimal antihypertensive regiment has not been defined. Objective: The purpose of this review is to present the proposed definitions for the metabolic syndrome, as well as the prevalence of hypertension in this condition. Moreover, evidence regarding the metabolic properties of the different antihypertensive drug classes and their effect on MetS will be displayed. Method: A comprehensive review of the literature was performed to identify data from clinical studies for the prevalence, pathophysiology and treatment of hypertension in the metabolic syndrome. Results: Hypertension is present in almost 80% of patients with metabolic syndrome. The use of thiazide diuretics and b-blockers has been discouraged in this population; however, new evidence suggests their use under specific conditions. Calcium channel blockers seem to exert a neutral effect on MetS, while renin-angiotensin system inhibitors are believed to be of the most benefit, although differences exist between the different agents of this category. Conclusion: Controversy still exists regarding the optimal antihypertensive treatment for hypertension in MetS. Due to the high prevalence of hypertension in this population, more data from clinical trials are needed in the future.

From the metabolic syndrome to the concept of global cardiometabolic risk

2009 ◽  
Vol 150 (18) ◽  
pp. 821-829 ◽  
Author(s):  
Judit Nádas ◽  
György Jermendy
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Central Obesity ◽  
Cardiometabolic Risk ◽  
Adult Population ◽  
Continuous Treatment ◽  
The Metabolic Syndrome ◽  
Cardiovascular Morbidity And Mortality

Although the clustering of cardiovascular risk factors is unquestionable, the clinical significance of the metabolic syndrome as a distinct entity has been debated in the past years. Recently, the term ‘metabolic syndrome’ has been replaced by ‘global cardiometabolic risk’ which implies cardiovascular risk factors beyond the metabolic syndrome. The metabolic syndrome can be frequently detected among people in western and developing countries affecting 25-30% of adult population, and its prevalence rate is increasing. Prospective studies show that the metabolic syndrome is a significant predictor of incident diabetes but has a weaker association with cardiovascular morbidity and mortality. At the same time the metabolic syndrome is inferior to established predicting models for either type 2 diabetes or cardiovascular disease.The underlying pathomechanism of the metabolic syndrome is still poorly understood. The role of insulin resistance – although not as a single factor – is still considered as a key component. In the last decade the importance of abdominal obesity has received increased attention but some studies, mainly in the Asian population, showed that central obesity is not an essential component of the syndrome. Regardless of the theoretical debates the practical implications are indisputable. The frequent clustering of hypertension, dyslipidaemia and glucose intolerance, that often accompanies central obesity, can not be ignored. Following the detection of one risk factor, the presence of other, traditional and non-traditional factors should be searched for, as the beneficial effect of intensive, target oriented, continuous treatment of metabolic and cardiovascular risk factors has been proven in both the short and long term.

scholarly journals Coffee consumption is associated with a lower risk of prostate cancer: a meta-analysis

2020 ◽  
Author(s):  
Xiaonan Chen ◽  
Yiqiao Zhao ◽  
Zijia Tao ◽  
Kefeng Wang
Keyword(s):  
Prostate Cancer ◽  
Cancer Risk ◽  
Cohort Studies ◽  
Linear Trend ◽  
Meta Analysis ◽  
Prostate Cancer Risk ◽  
Coffee Consumption ◽  
Significant Heterogeneity ◽  
Inverse Association ◽  
Coffee Intake

Abstract Background Although in vitro and in vivo experiments have suggested that coffee may exert inhibitory effects on prostate carcinogenesis, epidemiological studies have reported inconsistent results on the association between coffee consumption and prostate cancer. Methods We conducted a meta-analysis of cohort studies to assess the association between coffee consumption and prostate cancer risk. PubMed and Embase were searched for eligible studies up to Jan 2020. Study-specific risk estimates were combined using fixed or random effects models depending on whether significant heterogeneity was detected. Results Fifteen prospective cohort studies, with 50,200 cases of prostate cancer and 949,752 total cohort members, were included in the meta-analysis. A statistically significant inverse association was detected between coffee consumption and prostate cancer risk. The pooled relative risk (RR) was 0.91 (95% CI: 0.84, 0.98; I 2= 53.2%) for the highest coffee consumption compared with lowest consumption. The association exhibited a linear trend ( P =0.006 for linear trend), and the pooled RR was 0.989 (95% CI: 0.982, 0.997) for an increase of 1 cup of coffee per day. The pooled RRs were 0.93 (95% CI: 0.87, 0.99), 0.88 (95% CI: 0.71, 1.09) and 0.84 (95% CI: 0.66, 1.08) for localized, advanced and fatal prostate cancer, respectively. No publication bias was detected. Conclusions Our findings provide more evidence that increased coffee consumption is associated with lower prostate cancer risk. It implies that men might be encouraged to increase the coffee intake to lower their risk of prostate cancer.

Effects of TNF-α antagonist infliximab on fructose-induced metabolic syndrome in rats

2020 ◽  
pp. 096032712096996
Author(s):  
Yasmine A Abdelhamid ◽  
Mohammed F Elyamany ◽  
Muhammad Y Al-Shorbagy ◽  
Osama A Badary
Keyword(s):  
Metabolic Syndrome ◽  
Body Weight ◽  
Adult Population ◽  
Health Issues ◽  
Serum Triglycerides ◽  
Fructose Intake ◽  
The Metabolic Syndrome ◽  
High Fructose ◽  
Affect Body Weight ◽  
Tnf Α

Public health issues have been raised regarding fructose toxicity and its serious metabolic disorders. Deleterious effects of high fructose intake on insulin sensitivity, body weight, lipid homeostasis have been identified. The new millennium has witnessed the emergence of a modern epidemic, the metabolic syndrome (MS), in approximately 25% of the world’s adult population. The current study aimed to investigate the effect of the TNF-α antagonist infliximab on fructose-induced MS in rats. Rats were administered fructose (10%) in drinking water for 12 weeks to induce the experimental MS model. infliximab (5 mg/kg) was injected once weekly intraperitoneally starting on the 13th week for 4 weeks. Increase in body weight, blood glucose level, serum triglycerides (TGs), adiponectin level and blood pressure were present in MS rats. They also prompted increases in serum of leptin, TNF-α, and malondialdehyde (MDA) levels. Treatment with infliximab did not affect body weight, hyperglycemia or hypertension, but decreased serum TGs and increased serum HDL-c levels. Infliximab also decreased adiponectin levels. Surprisingly, infliximab increased MDA above its value in the MS group. These results reflect the fact that infliximab affects the manifestations of MS in rats. Though infliximab reduced TGs, increased HDL-c levels, reversed adiponectin resistance occurred by fructose, the drug failed to combat MS-mediated hyperglycemia, hypertension, and elevated MDA above the insult.

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