On the Natural Occurrence of Herpetomonads (Leptomonads) in Mice

Parasitology ◽  
1915 ◽  
Vol 8 (1) ◽  
pp. 128-132 ◽  
Author(s):  
H. B. Fantham ◽  
Annie Porter

While engaged in experimental researches on the introduction of insect flagellates, belonging to the genera Herpetomonas and Crithidia, into vertebrates, we have recalled to mind some former observations of ours made in 1909. When examining the blood of mice artificially infected with the spirochaetes of relapsing fever in the Quick Laboratory, Cambridge, we observed flagellates in the peripheral blood of the mice. These flagellates, which were scanty, were studied in fresh preparations by us and drawings of the organism were made with the camera lucida. Some of these drawings are now reproduced, together with others made by us subsequently. The flagellates were also observed by Professor Nuttall and his laboratory assistant, Mr B. G. Clarke, and we were unanimously agreed that the flagellates belonged to the genus Herpetomonas, or Leptomonas as some have since preferred to call it. The significance of the presence of herpetomonads in the blood of mice was very puzzling at the time, and pressure of other work prevented the subject being followed up. During 1911 and 1912, these flagellate organisms have been seen by all of us, but they were always evanescent and could not be found in fixed and stained preparations. The parasites were seen on different occasions in three mice altogether.

1832 ◽  
Vol 122 ◽  
pp. 279-298 ◽  

The splendid discoveries which have lately been made in magnetism and electro-magnetism have so much engaged the attention of philosophers, that the theory and laws of action of voltaic electricity, no longer possessing the charms of novelty, have been entirely neglected. The subject appearing to me full of interest, and lying at the very foundation of a large portion of physical science, induced me to undertake an experimental investigation of some of the most important points connected with it, the result of which I have the honour of laying before the Royal Society.


Think India ◽  
2019 ◽  
Vol 22 (3) ◽  
pp. 72-83
Author(s):  
Tushar Kadian

Actually, basic needs postulates securing of the elementary conditions of existence to every human being. Despite of the practical and theoretical importance of the subject the greatest irony is non- availability of any universal preliminary definition of the concept of basic needs. Moreover, this becomes the reason for unpredictability of various political programmes aiming at providing basic needs to the people. The shift is necessary for development of this or any other conception. No labour reforms could be made in history till labours were treated as objects. Its only after they were started being treating as subjects, labour unions were allowed to represent themselves in strategy formulations that labour reforms could become a reality. The present research paper highlights the basic needs of Human Rights in life.


2018 ◽  
Vol 11 (2) ◽  
pp. 41-51 ◽  
Author(s):  
I. Ya. Lukasevich

The subject of the research is new tools for business financing using the initial coin offering (ICO) in the context of the development of cryptocurrencies and the blockchain technologies as their basis. The purpose of the work was to analyze the advantages and disadvantages of the ICO in comparison with traditional financial tools as well as prospects, limitations and problems of using digital financial tools. Conclusions are made in relation to possibilities, limitations and application areas of digital business financing tools, particularly in the real sector, taking into account the specifics of the Russian economy and legislation. It is shown that the main problems of using the digital financial tools are related to the economic sphere and caused by the lack of adequate approaches to evaluation of assets as well as the shortage of objective information. The problems and new tasks of corporate finance in the digital economy are defined.


1983 ◽  
Vol 22 (1) ◽  
pp. 57-61
Author(s):  
Shahrukh Rafi Khan

The book under review is a compilation of the author's articles and lectures that highlight the prominent developments in the literature on the subject of Islamic banking and inform the reader of the current state of debate on it. One of the earliest and main contributors to this topic is the author himself. The focus of this review will mainly be on "Economics of Profit-Sharing", which is the title of the fourth chapter of the book and is among his latest contributions. This chapter is a significant contribution as it is the first attempt to formalise the concept of profit sharing into an analytical model and, therefore, demands closer scrutiny. However, in the remaining chapters of the book, the author has drawn attention to some of the fine points made in the literature on this topic. Since some of these points appear to be controversial to me, I will briefly discuss them before moving on to the analytical chapter of the book.


2020 ◽  
Vol 22 (2) ◽  
pp. 1-27
Author(s):  
João Carlos Brum Torres

O artigo tem por objeto o exame de três registros de gritantes e distintos paradoxos na Doutrina do Direito de Kant. Registros feitos em tempos e contextos históricos diferentes por Friedrich Bouterwek, Marcus Willaschek e Balthazar Barbosa Filho. Bouterwek atribuiu a Kant a mais paradoxal das proposições jamais enunciadas por qualquer autor, a de que a mera ideia de soberania deve obrigar-nos a obedecer como a nosso inquestionável senhor a quem quer que se haja estabelecido como tal, sem que caiba indagar quem lhe deu o direito de comandar-nos. Willaschek aponta a incompatibilidade de duas teses centrais da doutrina kantiana: a do caráter externo dos vínculos jurídicos e a da incondicionalidade obrigacional do direito positivo, pois não é possível entender como é possível termo-nos como obrigados por imperativos jurídicos e, ao mesmo, vermo-nos internamente isentados do dever de obedecê-los. O ponto crítico de Balthazar é alegar que não pode haver na filosofia kantiana uma crítica da razão político e jurídica, simplesmente porque o conceito de imputação, base da normatividade própria dessas esferas, pressupõe uma pluralidade de agentes livres que, justamente, só pode ser uma pressuposição, pois nosso acesso à normatividade prática só pode ter lugar em primeira pessoa. No exame a que o artigo submete essas alegações, o artigo argumenta, em objeção à tese de Balthazar, que o caráter universal e categórico da força que vincula o sujeito quando confrontado com a lei moral em primeira pessoa necessariamente se desvaneceria se, ao mesmo tempo, ele não fosse tomado pela evidência de que a realidade objetiva dos princípios morais é não só instanciável, mas assegurada pela múltipla instanciação. Com relação às dificuldades levantadas por Willaschek e Bouterwek, o artigo argumenta que o princípio exeundum e statu naturali, enquanto norma metapositiva, anterior à divisão do domínio prático entre doutrina do direito e doutrina da virtude, permite ao mesmo tempo compreender a exigência de obediência ao poder constituído e a restrição das obrigações jurídico-políticas exclusivamente ao foro externo.AbstractThe object of the article is to examine three claims about three distinct and allegedly blatant paradoxes in Kant's Doctrine of Right. These three critical points had been made in distinct times and contexts by Friedrich Bouterwek, Marcus Willaschek e Balthazar Barbosa Filho. Bouterwek attributed to Kant the most paradoxical of all paradoxical propositions, the statement that by the mere idea of sovereignty we are obliged to obey as our lord who has imposed himself upon us, without questioning from where he got such right. Willaschek points out the incompatibility of two main theses of Kantian doctrine of right: the claims that the legal bounds are of external character and that they are the source of unconditional obligations, since it seems impossible to understand how it would be possible to be obliged by juridical norms and decisions and at the same time to be exempted of the internal duty of compliance. The radical objection of Professor Balthazar is the claim that in the context of Kantian Philosophy it is impossible to admit a critique of the juridical and political reason because the concept of imputation, ground of the normativity in these domains, requires not only the presupposition of free agents, but a true and secure epistemic access to them, which is, according to him, impossible considering that the moral law and the other practical principles are accessible for us only in the first person. In the course of the appraisal of such claims, the article contest that objection arguing that the universal and categorical force of the normative bound experienced by the subject when confronted with the moral law in the first person would ineluctably vanish if, at the same time, he had not been taken by the evidence that the objective reality of the moral principles is secured by multiple instancing. Regarding the difficulties raised by Willaschek and Bouterwek, the article argues that the principle exeundum e statu naturali, as a norm of meta-positive character, prior to the division of practical domains between the doctrine of right and the doctrine of virtue, is the cue both to the understanding of the requirement of unquestioning obedience to the constituted power and to the restriction of the validity of this requirement only in foro externo.


Author(s):  
Steven J. R. Ellis

This chapter examines the socio-economic motivations behind the shaping of retail landscapes in Roman cities. It is about who opened retail outlets, as well as why and where. After critiquing some of the normal methods for illustrating the locations of shops and bars, including the conventional distribution plan itself, as well as questioning the economic rationality of operating tabernae, this chapter argues for the value in complicating our otherwise basic understanding of why urban investments were made in the places we find them. Rather than accepting profit as the single motivation to urban investment, a range of social, economic, and political motivations are considered as an explanation for the ultimate shape of Roman retail landscapes. Thus beyond discussions of space and urban topography, the subject of this chapter is investment.


Sensors ◽  
2021 ◽  
Vol 21 (14) ◽  
pp. 4901
Author(s):  
Lucjan Setlak ◽  
Rafał Kowalik

Sometimes, it is impossible to conduct tests with the use of the GNSS system, or the obtained results of the measurements made differ significantly from the predicted accuracy. The most common cause of the problems (external factors, faulty results) are interference disturbances from other radio telecommunication systems. The subject of this paper is to conduct research, the essence of which is an in-depth analysis in the field of elimination of LTE interference signals of the GNSS receiver, that is based on the developed effective methods on counteracting the phenomenon of interference signals coming from this system and transmitted on the same frequency. Interference signals are signals transmitted in the GNSS operating band, and unwanted signals may cause incorrect processing of the information provided to the end-user about his position, speed, and current time. This article presents methods of identifying and detecting interference signals, with particular emphasis on methods based on spatial processing of signals transmitted by the LTE system. A comparative analysis of the methods of detecting an unwanted signal was made in terms of their effectiveness and complexity of their implementation. Moreover, the concept of a new comprehensive anti-interference solution was proposed. It includes, among others, information on the various stages of GNSS signal processing in the proposed system, in relation to the algorithms used in traditional GNSS receivers. The final part of the article presents the obtained research results and the resulting significant observations and practical conclusions.


2002 ◽  
Vol os9 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Raman Bedi ◽  
Jackie A Champion ◽  
Roger Davies

Introduction In order to promote training and education in special-needs dentistry an attempt was made to introduce problem-based learning (PBL) as a method of postgraduate dental education. The aim of this paper was to review the principles of PBL and report on a case study using this methodology. Method The case study was of a PBL session, on the subject of ‘problems of obtaining appropriate dental care for people with epilepsy’, undertaken at a national conference. Delegates were asked to complete a pre- and post-session questionnaire on PBL and their attitudes to the session. Results The session received a mixed response. Only 33 (35%) thought the session was valuable and only 20 (31%) thought it was better than conventional teaching methods and yet over half (55%) said they would like to attend more PBL in special-needs dentistry. Professionals complementary to dentistry were more likely to find the PBL session of value and to prefer the method to a more conventional format than dentists were (chi-square=5.5, df=1, p<0.05 and chi-square=5.9, df=1, p<0.05 respectively). Conclusion Valuable feedback was received from delegates. This will enable improvements to be made in future courses so that the effectiveness of PBL can be optimised.


1867 ◽  
Vol 157 ◽  
pp. 89-107 ◽  

1. The principle of the conservation of force, as I apprehend it, is the definite quantitative relation existing between all the phenomena of the universe whatsoever, both in direction and amount, whether such phenomena be considered in the relation of cause and effect, or as antecedent and consequent events. 2. In the particular application of this principle to the advancement of physical science, and also to the invention of new engines and machinery to meet the progressive requirements of society, problems not unfrequently present themselves which involve the consideration of static and dynamic force, from several different aspects; and the solution of these problems often brings out results which are as surprising as they are paradoxical. Of such cases, in which the idea of paradox alluded to is involved, may be mentioned the one contained in the 36th Proposition of Newton’s 'Principia' (Book 2, Cor. 2), and in D. Bernoulli’s 'Hydrodynamica,' p. 279; in which the repulsive force of a jet of Water issuing from a hole in the bottom or side of a vessel with a velocity which a body would acquire in falling freely from the surface, is equal to the weight of a column of water of which the base is equal to the section of the contracted vein and about twice the height of the column which produces the flowing pressure; the static force of reaction being thus double that which, without experiment, had been predicted. An instance in which the quantity of dynamic force is increased paradoxically may be seen in that curious and useful piece of apparatus the injector, by means of which a boiler containing steam of high pressure is able to feed itself with water through a hole in its shell, though this hole is open to the atmosphere; or the steam from a low-pressure boiler is enabled to drive the feed-water through a hole (also open to the atmosphere) into a high-pressure boiler. Although, when rightly interpreted, these examples of paradox, as well as many others of a similar character, are in strict accordance with the principle of conservation, yet they are at the same time contrary to the inferences which are generally drawn from analogical reasonings, and to some of those maxims of science which are framed for the instruction of the unlearned. As the examples cited are only adduced for the purpose of illustrating some analogous phenomena observed in connexion with certain combinations of static and dynamic force in molecular mechanics which form the subject of the present research, it is not my intention to enter into the rationale of either of them, but to direct attention to some new and paradoxical phenomena arising out of Faraday’s important discovery of magneto-electric induction, the close consideration of which has resulted in the discovery of a means of producing dynamic electricity in quantities unattainable by any apparatus hitherto constructed.


The stage which the question of the function of the pelvic filaments of the male Lepidosiren had reached before the researches described in this paper can be seen by reference to the paper by Carter and Beadle (1930) and that by Cunningham in the previous year. The researches of Carter and Beadle as well as those previously carried out by Graham Kerr were made in the Gran Chaco of Paraguay, in the swamps of which region Lepidosiren is rather abundant. But when direct experiments on the function of the filaments were contemplated the political conditions made it inadvisable to attempt to visit this region, and it was suggested that Lepidosiren would be found in sufficient abundance on the island of Marajó at the mouth of the River Amazon. No evidence was obtained that the fish had recently been taken in that island, but three specimens, all from the same locality, namely a “papyrus meadow” near Fazenda Dunas on the north coast of the island, were recorded in 1896 and 1898 by Dr. Goeldi, Director and founder of the Muséu Goeldi at Belem. It was therefore decided to organise and carry out an expedition to Marajó. The equipment was prepared in the Physiological Department of the London Hospital Medical College and consisted of large glass tubes from 18 inches to 30 inches in length and 1½ inches to 3 inches in diameter; and weighed quantities in hermetically sealed tubes or bottles of the reagents required for the estimation of dissolved oxygen in water, together with the necessary accessories, and a special pump for obtaining water from below the surface of swamp pools.


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